Pancreatic cancer was almost invincible. A new targeted therapy just doubled survival

Pancreatic cancer has been, for decades, one of the biggest challenges of modern oncology. Its diagnosis usually arrives late and therapeutic options in advanced stages have historically been limited, accompanying a mortality very high. But a new experimental drug has hit the table by promising to double survival in patients who have the most severe forms of the disease. The protagonist of this revolution is called daraxonrasib and has come to light together with the data recently presented at the American Society of Clinical Oncology congress that has shaken the medical community, confirming that we are facing a possible paradigm shift for a disease that had not received good news for too long. More months. To understand the magnitude of the advance, you have to look at the results of the phase 3 trial, called RASolute 302. This study has focused on patients with metastatic pancreatic ductal adenocarcinoma who had already received previous treatments without success. Until now, the standard therapy, which is the well-known chemotherapy, in this second line of treatment offered a median overall survival of just 6.7 months. But it has been seen that, when administering daraxonrasibthe median overall survival shot up to 13.2 months. That is, practically double. And there is more. The trial, considered the first large phase three study of a drug of this type in this context, not only demonstrated an improvement in lifespan, but also in disease progression-free survival and in the objective response rate of tumors. The endorsement Although it may seem very promising and fanciful, we are seeing that this therapy is based on a scientific basis that had already been audited and published at the highest level. By this we refer to the published results of the previous phases of this trial that were public in The New England analyzing 168 previously treated patients, and a powerful antitumor activity was seen. But it is not without problems, since the NEJM article detailed that about a third of patients experienced significant adverse effects. However, in the context of metastatic pancreatic cancer, the risk-benefit balance is considered extraordinarily promising. An invincible enemy. The real technical triumph of daraxonrasib is its mechanism of action, since pancreatic cancer is known to be largely driven by mutations in the RAS gene family, and especially KRAS. And for more than 30 years, the scientific community considered that proteins mutated by KRAS were impossible to medicate. But now daraxonrasib is a multi-RAS inhibitor that acts on the mutations of this very specific protein that were the gateway to pancreatic cancer. This makes it the first pancreatic targeted therapy capable of offering sustained responses over time. The Spanish accent. The arrival at phase 3 does not mean that the research ends here, but rather that the scientific community is already looking for a way to enhance this drug with other drugs to prevent the tumor from ‘learning’ to endure it. In this field of preclinical biology, the work of Spanish researchers stands out. The group of the prestigious scientist Mariano Barbacid has already documented work in animal models using a triple combination that includes daraxonrasib along with other drugs that have been on many people’s lips recently. Images | MedinePlus CDC In Xataka | The Chinese company Alibaba has an AI to detect pancreatic cancer. It is so good that the US has accelerated its approval

It’s a survival strategy

On July 7, the Noto Satoyama airport, in the Ishikawa prefecture in Japan, will open its doors again with a new name and design: The classic corridors and high ceilings of aseptic light colors will give way to a more theme park aesthetic because that day it will be called “Noto Satoyama Pokémon With You Airport” and yes, it will be a Pokémon themed airport. Pokémon airport. This intervention will change the aesthetics of the airport from beginning to end: The main atrium, entrance columns, boarding gates and commercial spaces will have elements of the video game and entertainment franchise that just turned 30 years old. The star element will be a giant Pikachu balloon along with a replica of an aircraft inside the terminal, surrounded by representations of 111 species of Flying-type Pokémon. In the access columns there will be several Pokémon to generate an immersive experience from the beginning. Why is it important. The change of face and name aims to reactivate the flow of visitors to a region that continues to recover from one of the worst natural disasters in its recent history, the earthquake of January 1, 2024. The idea is to use a transportation infrastructure with direct international traffic in a tourist attraction to regenerate the territory’s economy. Pokémon It is the most successful franchise in the world and of all times, with an estimated brand rating in more than 100,000 million dollars and about estimated income of 147,000 million dollars. Associating a public infrastructure with such a successful asset represents an enormous visibility lever. All you have to do is take a look at the stratospheric numbers of the Pokémon GO Fest: in 2024 it generated 200 million dollars in Madrid, New York and Sendai, according to Niantic Labs. Context. The 2024 earthquake affected the Noto peninsula (where the airport is) and had a magnitude of 7.6. The figures of the earthquake are horrifying: 228 deaths, 30,000 buildings destroyed or seriously damaged, transport routes unusable, ports unusable due to the rise of four meters in sea level, as Nippon account. The Japanese government estimated a damage cost of up to $17.6 billion. This transformation is not only a matter of marketing: it is also a matter of connectivity and marketing of the region. Ishikawa’s reconstruction plan was structured in three phases. First came housing and restoring infrastructure, with the aim of returning normality and promoting the economic and cultural development of the prefecture. The Japanese Prime Minister himself explained in 2025 that this “creative” reconstruction of the Noto airport at the February 2025 follow-up meeting, noted that the creative reconstruction of the Noto region should serve as a reference model for the recovery of rural areas throughout the country. In this framework, the themed airport fits as an emblematic project within the official reconstruction strategy. MDPIPrime Minister’s Office of Japan How are they doing it. This reconstruction will be carried out through public-private collaboration between Ishikawa Prefecture and the Pokémon Foundation of Japan. The design of the venue will be based in the 111 Flying-type Pokémon as the thematic common thread, displayed at all contact points for those who step foot in the airport from the first moment: façade, columns, transit area, boarding gates and even the gastronomic proposal, with pancakes and themed drinks served on exclusive placemats. The commercial area will offer limited edition products such as t-shirts, keychains and luggage accessories, so that the airport is more than just a connecting link to reach your destination: the airport itself will also offer its own unique experience, especially interesting for fans of the saga. Yes, but. Converting a critical infrastructure such as an airport into a hybrid between airport and theme park has its B side: it depends enormously on the future of the brand and the cost of maintenance increases, as it requires investment in new content, aesthetic renewal or licenses. And how warns Bloombergdepopulation and reduced tax revenues in Japan are making it difficult to maintain basic infrastructure and recover from disasters in rural areas. If the flow of visitors does not reach the profitability threshold, the initiative can become a heavy burden for a region that is already undergoing a very expensive reconstruction process. In Xataka | In 2016, millions of people went out to hunt Pokémon on the streets. In 2026 there will be autonomous robots guided by this In Xataka | Younger millionaires have found a more profitable investment than the S&P500: Pokémon cards Cover | PR Times

Today the latest from a master of horror arrives on Disney+, a survival show that was about to end up in a drawer

The last time before this year that Sam Raimi directed a horror film was in 2009, with ‘Drag Me to Hell’, a return to his roots after the ‘Spider-Man’ trilogy and which remains, perhaps, his best film along with ‘Darkman’ and the ‘Evil Dead’ trilogy. After extensive work in the ‘Oz’ franchises and Marvel, he returns to the humor, suspense and violence of that marvel with this fantastic ‘Send Help‘you just landed on Disney+. In it we will meet a shy and lonely woman (Rachel McAdams) who travels with her arrogant and insufferable boss on a flight that ends up having an accident and leaving them on a desert island in the Pacific. What begins as a survival story becomes an inversion of the work hierarchy: the person who knows how to survive in nature is not the same person who rules in the office. From there, a strange and hilarious mix of ‘Cast Away’ and ‘Misery’ that doesn’t cut corners either in the intensity of its most violent scenes or in the grotesque humor with which it portrays its protagonists. The original idea for the film dates back to before the pandemic, when Raimi came across this script from the authors of ‘Freddy vs. Jason’. When COVID happened, cuts came to the industry, and the studio tried convince the director to reduce the budget and release it on platforms. Raimi wanted the production to reach theaters, so the project was presented to the former Fox, now owned by Disney. In an especially profitable year for traditional horror films like ‘Sinners’ or ‘Weapons’, and for thrillers with a twist like the hit ‘The assistant‘, ‘Send Help’ is placed, as is usual for Raimi, in an intermediate and unclassifiable terrain. Extremely dark humor, a description of characters between social caricature and classic horror comics and a load of impossible plot twists for the enjoyment of those who think that plot coherence is for the weak when there is emotion and narrative pulse. In Xataka | Netflix premieres today the dystopian series that has risen to the throne of the best in history in six seasons

A survival thriller coming to Netflix tomorrow that pits Charlize Theron against a psychopath in the depths of Australia

A murderer chooses his victim carefully. That’s what Ben (Taron Egerton) does when he determines that Sasha (Charlize Theron), an elite climber who has entered the outback Australian to overcome a duel, is his next objective. What Ben doesn’t know is that Icelandic director Baltasar Kormákur has spent twenty years specializing in placing extraordinary actors in devastating environments. The result of this clash receives the poor translation of ‘Dominant predator‘in Spain (the original is the most elegant’Apex‘), premieres on April 24 on Netflix and is pure popcorn party. Shot entirely in real locations, the film put Egerton and Theron, who are joined by Eric Bana, to the limit of their strength. In fact, Theron suffered a broken toe during filming and continued filming without anyone on the crew knowing. A good example of how the film posed a challenge for its performers that went beyond the strong psychological tension that is drawn between the two rivals. In fact, The approach of ‘Apex’ is one of the oldest in action cinema: The short story ‘The Most Dangerous Game’ by Richard Connell, published in 1924, described an aristocrat who hunted humans on his private island, and inspired a total classic of the genre in 1932, ‘The Evil Zaroff’. From there, multiple variants of the “people hunting” trope, and which is often, as here, accentuated by a danger that is added to the relentless hunters: an environment that functions as a gigantic trap. ‘Apex’ director Baltasar Kormákur has spent two decades building a filmography around a single question: what does extreme adversity do to people? His most relevant survival films, ‘Everest’ (inspired by a real catastrophe in 1996), ‘Adrift’ (about a couple trapped in the ocean after a hurricane), and ‘The Beast’ (where Idris Elba confronts a lion in South Africa), have common characteristics: real locations, actors subjected to harsh physical conditions and landscapes that are both scenery and threat. This new Netflix exclusive ‘Apex’ plays in that same league. In Xataka | 16 premieres on Netflix: this week, the new ‘Stranger Things’, a rare British series and the return of Charlize Theron

We believed that procrastination was a time management problem. Neuroscience has shown that it is a survival instinct

Almost all of us have been in the situation of being faced with a task that must be done no matter what, such as studying an exam or handing in an assignment. We know that it is something important, and that we should start addressing it now, but suddenly we are doing something totally different and insignificant like reorganizing the drawer or watching a video on YouTube. What seems so common is what we call procrastinationand we understand more and more why we do it. The context. For decades, popular culture has told us that procrastination is a time management problem or, worse yet, simple laziness. However, neuroscience has a very different message when it points out that procrastination It is not an organizational failure, it is a crisis of emotional regulation. The brain. To understand procrastination, we must first look at the anatomy of our brain, which often functions as a large battlefield divided into two sides. On the one hand we have the limbic system, which is one of the most primitive parts of the brain and whose function is simply to keep us alive, away from pain and seeking immediate pleasure. On the other hand, we have the prefrontal cortex, which is the most evolutionarily ‘modern’ area, located right on the forehead. This is where we have rational thinking, long-term planning and logic. What is known. Already a 2021 review pointed out that these areas are activated when you have to do a task that generates anxiety, boredom or insecurity, such as studying an exam. And it is no wonder, because the limbic system detects this situation as a “threat”, and automatically hijacks the prefrontal cortex to prioritize immediate emotional relief by looking at Instagram over the long-term benefit of starting to study to pass. We know more. Now, this year, a new study has taken a new step to understand this brain system, by identifying in primates a specific neuronal circuit that functions as a “brake” for motivation, and that connects two parts of the brain: the ventral striatum (VS) with the ventral pallidum (VP). The researchers discovered that when we face tasks associated with discomfort or the possibility of failure, this VS-VP circuit is activated, inhibiting the action, as if it were an emotional protection mechanism taken to the extreme. The most striking thing about the study is that, by interrupting this circuit in the laboratory, the subjects immediately restored their motivation, “releasing the brake” and tackling the difficult task. It’s not laziness. This new line of research is consistent with previous research that associated procrastination with stress, fear of failure, and anxiety. In this way, when seeing a blank document or a very complex Excel sheet, the amygdala activates a flight response. In fact, it has been seen that chronic procrastinators tend to have worse connectivity between the amygdala. the anterior cingulate cortex, which makes them less able to filter negative emotions and distractions. In short, the brain will procrastinate to protect itself from the psychological discomfort caused by a task. Hacking. Seeing how complex this all is, blaming yourself or calling yourself “lazy” is of no use. But it is true that you have to follow a strategy to be able to hack our perception of stress and reward, starting to break up the work, making it so that, instead of setting out to “write the entire work”, you should opt for “write only the title and the first paragraph for five minutes” to trick the amygdala. It is also possible to block sources of easy dopamine with a blocking system on your computer or mobile phone that makes it difficult to access Instagram or YouTube to watch a video. This way, if the immediate reward requires an effort like going to the next room for the phone, the prefrontal cortex has time to intervene and put us in concentration mode. Images | Ashkan Forouzani In Xataka | Procrastinating is a death trap for your brain in the form of anxiety. The problem is that we don’t know how to avoid it.

Someone has put everything they need in a survival flash drive.

The massive arrival of the Internet and connected devices have implemented a half-truth in our daily lives: that there will always be connectivity. And it doesn’t have to be. I discovered it the hard way on April 28, 2025, the day of the blackout: Without cash, something as common as eating out and paying with a card became an impossible mission and involuntary fasting. With information, more of the same: the usual Wikipedia or Google Maps are of little use without the Internet (in fact, download the original is always a good idea). Someone has wondered what would be left on your computer when the Internet goes down and to address that uncomfortable but legitimate question, they have launched a “survival kit” that fits on a USB flash drive. You insert it into your PC, it boots directly from there and it comes with everything. Yes, also an AI assistant. The project. shelters is an open source project created by Spanish Spanish dev Javier Prieto. What it essentially offers is a lightweight variant of Ubuntu preconfigured with a selection of tools designed to work completely offline. The heart of the project is an installation script: you prepare a USB with the base system, you connect it to the Internet once to run that script and you no longer need the Internet. Why is it important. The refugiOS proposal solves a real problem that is often overlooked: the vulnerability of depending on the Internet and its infrastructure. In the event of a serious emergency, such as my blackout, but also natural disasters or conflicts, what the servers offer will be inaccessible. And it will be the time when you need them most. Having that data physically stored without the need for external and foreign infrastructure can make a difference. Emergencies aside, the project evidently also satisfies from a privacy point of view. Everything you consult in refugiOS stays on your machine. There are no servers that record your activity, conversations or routes or share them with the AI. In a context where data and its analysis are increasingly the order of the day, having tools that work without filtering data to the outside provide value beyond being useful in the event of a possible apocalypse. And it offers one more extra: total portability. What does shelter bring?. The available content is grouped into five blocks: Offline library and encyclopedias: Wikipedia, WikiMed and WikiHow thanks to Kiwix. Maps and GPS navigation with offline search and routes using Organic Maps. Artificial intelligence. An AI assistant run locally available in three power levels depending on the RAM of your computer: from the basic Phi-4-mini for any PC with 4 GB of RAM to Qwen3-14B that requires 16GB to Qwen3-8B, which requires 8GB. Encrypted file vault (LUKS standard) to protect sensitive files. General tools like LibreOffice, VLC or Syncthing. There are three AI models depending on the hardware of your computer. GitHub Context. There are a few digital resilience projects, including Kiwix, which has been distributing Wikipedia offline to areas without internet for years; but what refugiOS is about combining several of these options into an all-in-one, ready-to-use system, which is also accessible to someone who doesn’t have too much technical knowledge. And it also comes at the best time. On the one hand, because there has been a real boom in small and efficient language models (something that a couple of years ago was unthinkable) and on the other, because of the current situation: conflicts, the flooding of AI to each and every one of the Internet sectors or the shift of the American technological monopoly of the West towards a more invasive policy. refugiOS takes advantage of that technological window and opportunity to add a layer of comprehensive utility. In detail. The project has deliberately conservative design decisions in that it ensures that the system boots and runs smoothly on basic and/or veteran computers (with 4GB of RAM), being easy to maintain and distribute. In fact, the documentation explains how to copy it to pass it on to your people. Of course, its status is still quite incipient: it is functional, but with room for improvement in the interface, documentation and language coverage. However, its roadmap is ambitious, with thousands of public domain books through Project Gutenberg or support for shortwave radio receivers. In Xataka | Batteries, radio, power bank: the six basic technologies that we recommend for your own “survival kit” in the event of a blackout In Xataka | Someone has passed 12,000 laws and reforms to source code and now searching the BOE is no longer an ordeal Cover | Immo Wegmann and Marcel Eberle

OpenAI swore that ads on ChatGPT were its “last resort.” Now they are your survival plan

a couple of years ago Sam Altman said that placing ads on ChatGPT was “the last resort for our business model.” Well then, ChatGPT ads are here and OpenAI is sure that it will be the business of the century, one that will generate a whopping $100 billion. what has happened. He leaked it Axios; During a presentation with investors, OpenAI has confirmed its forecasts for the newly released advertising model in ChatGPT. During 2026 they expect to generate 2.5 billion dollars and this will increase in the coming years until reaching 100 billion in 2030. This is the progression they project: 2026: 2.5 billion 2027: 11,000 million 2028: 25,000 million 2029: 53,000 million Why it is important. Advertising has gone from being the last resort of its business model to directly being its business model. OpenAI is losing money at an unsustainable rate and has been making profound changes to be more profitable, such as focus more on enterprise customers, but it may be too late. Advertising is your way to profitability. In other words, your survival depends on this going well. butterfly effect. If it works for them and they achieve their goal, it can change the rules of online advertising. 100,000 million is many millions, enough for Google and Meta’s business to end up being affected. Furthermore, advertising within a chatbot like ChatGPT can be much more profitable because the user says in a much more direct and detailed way what they are looking for. On the other hand, advertising on Instagram or Google Ads requires work to collect data to guess the user’s tastes. If it doesn’t work for them, the outlook looks bad for the technology sector. We talk about the most valuable private company in the world and Its possible bankruptcy can cause a domino effect that freezes investments and punctures the expectations placed on AI. Users. To achieve these numbers, OpenAI estimates that it needs its weekly user base to reach 2.75 billion by 2030. Right now ChatGPT has 900 million weekly active usersthat is, they have to triple them in four years. We talked about ChatGPT having to be at the level of WhatsApp or YouTube. There is already 6 billion people with internet accessAs far as there are users, the question is whether it is feasible for OpenAI to attract almost half of them. The mass adoption of AI is already in a more mature phase and, although it is the most used, ChatGPT is no longer the pretty girl; Now it coexists with equally capable competitors and most importantly: The image of the company has been eroding. The double edge of advertising. Advertising can be tremendously lucrative for OpenAI, but it puts user trust at risk, and that is just what they need to fulfill their plans. We have normalized seeing ads everywhere, but having them appear in a conversation with a chatbot threatens to erode their main promise: to be assistants that respond solely to the user’s interest, and not to the commercial priorities of those who pay to advertise. Two things can happen here: that the rest of the AI ​​companies jump on the bandwagon and we normalize that the free versions have ads (the ideal scenario for OpenAI), or that OpenAI is left alone and people end up going to other ad-free chatbots. Anthropic said it would not advertisewe will see if in a few years they continue to maintain it. Image | Xataka In Xataka | Before, advertising was to monetize. Now it is to punish you and YouTube has taken it to the extreme

US and China governments threaten their survival in a crucial market

China is a very important market for Nvidia. During the last fiscal year, which expired on January 26, 2025, this Asian country represented approximately 13% of total income of the company led by Jensen Huang with a figure of some 17,000 million dollars. In Chinese practice it is the third best client of this company only behind the US and Taiwan, but The steps that the Trump administration is taking They threaten their survival in this market. In the middle of last April the US Department of Commerce imposed new restrictions to the export to China of the GPU for artificial intelligence (AI) H20what in practice caused this chip to stop arriving at the Chinese clients of this company. After weeks of negotiations, and even several “face to face” between Donald Trump and Jensen Huang, Nvidia has made the Department of Commerce allow her to re -give her Chinese clients her H20 chip. However, this permission has not left for free: hereinafter will deliver to the US government 15% of income which will obtain in China for the sale of this and other GPU. AMD has run this same luck, so there is no doubt that this Trump administration strategy establishes an unpublished precedent by forcing some US companies to deliver to the State a percentage of their sales income in another country. Nvidia has been dealing with Sale prohibitions in China Of most of his chips for AI, and has now been forced to fit this new blow. The US government ensures that he is protecting his interests and the security of the nation, but along the way he is also promoting that China develop their own technology at a vertigo speed. It is a full -fledged form of Autoboicot. The loss of confidence of the Chinese government has fired Nvidia alarms The future of Nvidia in China is largely in the hands of the administration of the cyberspace of China, known as CAC for its English denomination (Cyberspace Administration of China). This institution is the main Internet regulatory body in China and is thoroughly investigating NVIDIA H20 GPU Because it suspects that this chip could incorporate a back door of difficult location by Chinese experts. If so, the possibility of China to use this GPU could be possible. David reber Jr., Nvidia Security Director, published last week An article in the blog of this company entitled “There are no rear doors in the Nvidia chips. There are no deactivation switches. There are no spy software” in an obvious attempt to defend the company’s reputation and appease the growing distrust to which he faces in China. There is a lot at stake. If the final resolution of the CAC turns out to be unfavorable with all probability NVIDIA will lose a good part of the income currently obtained in this country. If the final resolution of the CAC turns out to be unfavorable with all probability NVIDIA will lose a good part of the income obtained in China However, this is not all. Whatever the CAC verdict is a fact that the Chinese government He is urging Chinese companies that are dedicated to the development of large models of AI to use in their servers integrated circuits of Chinese origin. In this scenario their best bazas are now Huawei and Moore Threads. The first of these companies has lists its own GPU for iathe chips ascend AI, for more than five years. During this period of time it has been refining them and increasing their abilities with the purpose of matching or even overcoming the performance of the chips A100 and H100 of Nvidia. His most ambitious proposal right now is the chip Ascend 910dwhich seeks to overcome the performance of the H100 GPU. However, this Chinese company has also recently presented its chip Ascend 920a solution that is clearly destined to occupy in the Chinese market The H20 GPU space. This proposal will enter large -scale production during the second half of 2025 using 6 NM integration technology that have presumably developed elbow with Huawei elbow and SMIC. On the other hand, Moore Threads He has developed several GPU for AI applications that, on paper, rivaize some of the advanced solutions that have placed in the Nvidia, AMD or Huawei market. The MTT S4000 and MTT S3000 cards are its most interesting proposals right now, although, curiously, in its porpholio the MTT S80 card, a proposal for games and content creation that, according to Moore Threads itself, has a 14.4 TFLOPS calculation capacity also appears in Floating Coma operations of simple precision. It doesn’t impress, but it’s not bad at all. Image | Gage Skidmore | Wikipedia In Xataka | Ten Chinese companies in Chips and IA have allied with a common goal: to put an end to the domain of Nvidia

His survival in China right now hangs from a thread

This time the joy has lasted little to Nvidia. Finally, like We explain to you on July 15the company directed by Jensen Huang has made the Department of Commerce review its regulation and allows you to sell The GPU H20 for artificial intelligence (AI) in China. “The US government has assured us that licenses will be granted. We hope to start deliveries soon,” Nvidia said In a statement. The H20 chip is very important for Nvidia because it has opened the doors of the Chinese market again. The reception that Chinese companies initially gave to this GPU was very good despite the fact that the capacities of this chip are clearly lower than those of the other proposals for this company. In fact, the US Department of Commerce allowed its sale in China because this integrated circuit fulfilled the restrictions that had imposed. And despite its limitations its sales in China 50% quarter to quarter grew Since he arrived in this market in mid -2024. The administration of the cyberspace of China is investigating Nvidia Surprisingly this scenario He has put Nvidia in Añuro. And, once again, the reception of the H20 GPU in China is being so good that this American company has run out of units. According to ReutersNvidia has commissioned TSMC for the manufacture of no less than 300,000 units of this chip to be able to respond to the current demand from China. Blessed problem. However, the company’s engineers have been working on A new GPU with Blackwell microarchitecture The latest generation that is intended to occupy in China the place of the H20 chip. Cyberspace administration is the main Internet regulatory body in China Anyway, everything is not going well for Nvidia. And it is that the administration of the cyberspace of China, usually known as CAC for its denomination in English (Cyberspace Administration of China), he has decided Thoroughly investigate the H20 GPU. This institution is the main Internet regulatory body in China. It is mainly responsible for the censorship and control of the contents published in the Network, the supervision of technology companies and compliance with the Data Security Law and the Personal Information Protection Law. However, this is not at all the first time that the CAC makes noise in the West. And is that on March 31, 2023 launched an investigation as its purpose audit Micron Technologythe largest American memory chips. On this occasion, the CAC has decided to investigate Nvidia because it suspects that the H20 Chip could incorporate a back door of difficult location by Chinese experts. If so, the possibility of China to use this GPU could be possible. At the moment the CAC has limited himself to questioning those responsible for Nvidia in China and ask them to demonstrate that the H20 chip It does not represent a threat to interest and security from the country led by Xi Jinping. At the moment we do not have much more information, but presumably Nvidia will do everything in your hands to guarantee your survival in the Chinese market. After all, during the last fiscal year, which expired on January 26, 2025, China represented approximately 13% of total income of the company led by Jensen Huang with a figure of about 17,000 million dollars. Image | Nvidia More information | Nikkei Asia | SCMP In Xataka | The US gives Huawei a great opportunity: to get its new chip for AI with the Nvidia market in China

There have always been people preparing for the Apocalypse. The difference is that they now include AI in their survival kits

For years there are people preparing for a nuclear war, for the end of the world, or For both. They are called ‘Preppers‘, that at times like the recent Spanish blackout They feel claimed. The movement is mutatingand as Mit Technology Review collects, the needs and possibilities of 2025 leave us people doing and proposing Collect Artificial Intelligence Language Models (AI) to save them in a USB pendrive. A good tool for the end of the world. The engineer Simon Willison, known for being the creator of the Django web development framework, has A plan For a future dystopian: keeping open artificial intelligence models, you can execute them at home if collapse civilization. In this way, even without internet access, it would be possible to continue accessing the enormous human knowledge located in its pesos. To carry out something like that, there is no need for resources beyond the reach of the homes of the homes. Today, there are already AI models that can be executed at home, Even in smartphones. Even something as powerful as Deepseek can work on our PCprovided we use a small version, the ‘distillate’ of 8,000 million parameters. As Share Evan Hahnthe Chinese Qwen 3 model, in its 600,000 parameters version, can occupy the ridiculous amount of 523 MB in our storage. With only 2 GB, we can download call 3.2 in its version of 3,000 million parameters. A powerful but “economical” team like a Mac Mini M4 can run models capable at home. An alternative to something more traditional: all Wikipedia. Download all the wikipedia To read it without connection, it is something possible with different options, and something equally useful in an apocalyptic scenario such as the proposal. Hahn has included what he would occupy with the great open language models, and using little space, enough information can be stored. With 356.9 MB we can access the 50,000 best articles in Wikipedia. And with 57.18 GB, which fit perfectly in a modern pendrive, we can have in our possession all the Wikipedia available in any language. Occupy less than half of the space, we can have QWEN 3 of 32,000 million parameters and Deepseek R1 of the same size. Limitations. Using artificial intelligence at home to have access to the knowledge of the world sounds very good, until not so much. Simon Willison himself told Mit Technology Review to use the local AI models “is like having a strange, condensed and defective version of Wikipedia.” The reason is simple: the models are trained with data available on the Internet, to the point that the AI bots are putting the future of Wikipedia at riskHowever, these models do not faithfully reproduce all the information when we enter Prompts o Indications to ask about a specific topic. The hallucinations problem. Not only are they confirmed by actors such as OpenAi, but for them we know that models such as O3 and O4-mini They hallucinate more than their predecessors. According to Jensen Huang, we need much more powerful hardware So that this phenomenon of AI disappears, and of course, it is not hardware that we have at home. In addition, small models executable at home, being very small versions in size and memory used, toThey look more. And more limitations. In our tests executing local AI models on smartphones, The results are irregularalthough promising. In that sense, Apple itself will open in iOS 26 his AI to any developerso that they can execute it on the device itself. Beyond the quality of small and local models against the gigantic Grok 4, O3-PRO either Claude 4 a ‘prepper’ plan with pendrive has more limitations, and is to trust such a unit for a situation that requires, above all, reliability. These USB units are not designed to last more than 10 years. If they have poor quality NAND chips, they can even stop working without use. And that is why there are companies like Machdyne UG, which has created a pendrive that It lasts 200 yearsor so they promise. Of course, even if I achieve that longevity, it has an 8 kB capacity, which only gives to save some text. If you want to store almost all the knowledge of humanity, it is best to think of a lasting environment in optimal conditions. And then, think about major disasters. Image | Antonio Sabán with Ia In Xataka | AI is one of the most advanced technologies that the human being has built. It also gets distracted with a cat

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