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In the 16th century someone decided that Da Vinci’s notebooks had to be dismembered. It took us 400 years to solve their mistake.

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Upon his death, in 1519, Leonardo da Vinci He left more than just paintings and frescoes that crown him as one of the great references of Renaissance painting. Just as (or even more) important to understanding the depth of his genius are his personal notebooks, full of notesillustrations, graphics… come from his own handwriting and sprinkled with his characteristic mirror writing. By chance of history, in the 16th century this bibliographical treasure suffered a ‘act of editorial vandalism’ that has conditioned the way we understand Leonardo. Until now. An unfortunate legacy. The name of Francesco Melzi Maybe it doesn’t tell you much. And it’s normal. Melzi was an Italian painter of the 16th century whose memory has been eclipsed for posterity by geniuses of the stature of Michelangelo, Raphael Sanzio and Leonardo Da Vinci, of whom he was a disciple. However, Melzi does stand out for something, a role that has conditioned our way of understanding the author of ‘La Mona Lisa’: upon Leonardo’s death, Melzi became his executor, responsible for looking after his manuscripts. That enormous legacy made up of hundreds and hundreds of manuscript sheets ended up in the hands of Pompeo Leoni (1533-1608), a sculptor from Arezzo, in Tuscany, who one day decided to dismember Leonardo’s notebooks. The result was disastrous, although to be honest Leoni’s objective was not to destroy the notebooks, but to ‘reorganize’ them following an arbitrary criterion. And what was the result? Basically Leoni dedicated himself to separating, classifying and putting together sheets of Leonardo’s notebooks and loose pages in a whimsical way. Based on what he considered best. The result was that many of the annotations that Da Vinci had recorded in the same set of manuscripts between the mid-1470s and his death in 1519 were divided into two different codices. In one, the largest, Leoni included all material (drawings and writings) of a technical or scientific nature. The second, smaller codex was reserved for material that in his opinion had an artistic and figurative character. From Italy to England. Leoni’s ‘attack’ did not end there. At the beginning of the 17th century his son-in-law, Polidoro Calchi, decided to get rid of the material he had inherited from the sculptor, which caused Da Vinci’s old notebooks to end up scattered around the world, separated by hundreds of kilometers. The first codex, that of technical annotations, today known as Codex Atlanticusended up in the hands of Count Galeazzo Arconati, who in turn donated it in 1637 to the Veneranda Biblioteca Ambrosiana. The second codex traveled even further. Around 1620 he ended up in England and half a century later was integrated in the Royal Collection at Windsor. Righted the wrong. More than four centuries later that capricious dismemberment of Da Vinci’s annotations has been amended at last. At least in part. A few days ago the Italian embassy in the United Kingdom, the Ministry of Culture and representatives of the Galileo Museum, the Veneranda Biblioteca Ambrosiana and the Royal Collection Trust presented in London a new tool named ‘Leonardotheka 2.0’. The name gives a clue to its approach: it is nothing more nor less than an immense ‘library’ digital of Da Vinci’s legacy, a resource that allows many of the manuscripts of the Renaissance genius to be consulted in an accessible and agile way. The Galileo Museum slide that from now on, whoever wishes will be able to explore the material by accessing the archives independently or with cross searches, in addition to “the results of more than 200 years of research” on Da Vinci’s career and work. 3,500 pages. Beyond that advantage, what is really important about Leonardotheka 2.0. is that, as remember The authorities of Florence have gathered around 3,500 manuscript pages by Leonardo that in some cases had been separated since the end of the 16th century. It is a virtual union, not a physical one, but it is still a milestone and helps to right the mistake made centuries ago by Pompeo Leoni. In total, the digital library brings together the 1,119 folios of the Codex Atlanticus and 550 pages from the Royal Collection of Windsor. Some sources specify that it is about one third of Da Vinci’s entire surviving legacy, which also includes the codices preserved in Madrid. Is it that important? Regardless of what it may mean for researchers, Leonardotheka 2.0 is important for several reasons. The main one is that it has allowed us, in words of the Galileo Museum, “reconstruct the original state of Leonardo’s manuscript legacy before Leoni’s disastrous intervention” in the 16th century. And that is not a minor detail. Although the separation between art and science might make sense to Leoni, the truth is that goes against of the Renaissance mentality that Leonardo embodied. “It offers a new perspective on his thinking, vision and working methods,” they underline from Florence. “The platform highlights the connection between scientific studies and the figurative drawings of the Tuscan genius.” Beyond Leonardo. “This project not only helps to recover the complexity of Leonardo’s work in its original form, but also contributes to the new interpretation, in development for several years, of this crucial period in European history. Using digital tools designed to analyze the original texts, Leonardotheka 2.0 will make this challenge possible,” highlights Michele Ciliberto, from the National Institute of Renaissance Studies. Filling gaps. The second reason why the project is so important is that it has allowed us to recover pieces that had been damaged when the notebooks were dismembered in the 16th century. To be more precise, those responsible for the Leonardotheka they assure who have been able to “reconstruct” 50 manuscripts “thanks to the insertion of fragments preserved in Windsor within the pages of Codex Atlanticus, restoring their original context.” One of the reconstructions carried out by the experts has made it possible to “reconcile” the drawing of a horse preserved in the British collection with a note on an equestrian monument preserved in the Codex Atlanticus. “The restored folio probably … Read more

Spain had been using the cutter in pharmacies for half a century. Until you decided to digitize it

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Entering the pharmacy in 2026 and that the method to mark the traceability of the medicine was to cut a small tape with a cutter did not seem like the most technological method in a European country. Finally, it is something that will change forever. what has happened. The Council of Ministers yesterday approved the modification of Royal Decree 1345/2007which updates the regulation of the Spanish Medicines Verification System. Until now, upon arriving at the pharmacy the pharmacist would peel off or cut the seal from the box, paste it on a sheet of paper and this documentation would demonstrate to the administration that a prescription medication had been dispensed and that it would be reimbursed. This is about to end. The new. The Minister of Health, Mónica García, has celebrated the modernization of the new identification system. This relies on the national drug repositoryin operation since 2019 and which allows each medication to be identified using a unique code. “We’re talking about the sealed coupon. That’s what pharmacists did when you came to the pharmacy to pick up a drug and they had to cut out a piece of cardboard and paste it on a sheet of paper. Well, we’re going to eliminate all of that.” Monica Garcia. The difficulty of the process is that it is not enough to make the first identification: it is necessary to justify that this container cannot be re-introduced onto the market. To solve this problem, as advanced by the pilot test that was carried out in the Valencian Communitythe medication will be linked to the prescription, the buyer’s data and registered in the system. Nothing prevents the medication from circulating again through unofficial channels, but it is impossible for it to go through official channels again as new. Now each box will have a unique identity. The batch, expiration date and route of the medication are known. If a problem appears with a batch, you can know: which patients received it, in which pharmacy, how many containers were dispensed. not so fast. Palace things are going slowlyand more in Spain. The full transition has not been marked, and what we know to date is that the new system will coexist with the old. Once the integration of the systems in all the autonomous communities is completed, the traditional sealed coupon will disappear forever, in favor of a 100% digitalized model. In Xataka | After years of debate and 1,000 “medicines” withdrawn, Spain finally has a verdict on homeopathy: it is useless

We have turned probiotics into the miracle pill of the 21st century. Science has something to say about it

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They are in pharmacies, along with vitamins C and multivitamin complexes. They are on the shelves of organic supermarkets, between adaptogens and turmeric shots. They occupy the reels of TikTok with the same enthusiasm with which before detox juices populated. Probiotics – supplements with live microorganisms that supposedly strengthen the intestinal flora – have become the health amulet of the 21st century. The promise is simple and seductive: take these “good” bacteria in a capsule and your gut, your brain, your immune system, and your skin will function better. The business accompanies the promise. According to different estimates from the sectorthe global probiotics market was valued at around $114 billion in 2025 and is projected to continue growing at a sustained rate over the next decade. However, there is a problem that science has been contemplating for years: taken massively and indiscriminately, probiotic supplements not only do not improve the microbiome in the majority of healthy people. In some cases, they can actively block it. A forgotten organ that regulates almost everything. The human intestine is home to trillions of microorganisms—bacteria, fungi, viruses—that form an ecosystem as complex and personal as a fingerprint. According to gastroenterologist Chris Dammanfrom the University of Washington, who has been studying the microbiome for 20 years, this ecosystem acts as “the gateway to the body’s overall health.” Diets with more fiber, fruit and vegetables are those that generate the greatest variety and richness of bacteria in the intestine, and healthy bacteria produce short-chain fatty acids that support the health of the intestinal lining, according to the clinical documents of the Whole Health from the US Veterans Administration. The microbiota is not just digestion. A review published in the journal Nutrients by researchers at the University of Cassino in Italy, details how the gut microbiota modulates neurochemical pathways involving serotonin, dopamine, GABA and glutamate, as well as the immune and endocrine axes. Microbial imbalance—what scientists call dysbiosis—contributes to low-grade systemic inflammation, impaired neuroplasticity, and altered stress responses, all of which are linked to mood disorders and cognitive decline. However, the most striking fact is that Approximately 95% of the body’s serotonin is synthesized in the intestinenot in the brain. Whether the intestine is good or bad is no small matter. Take care of the microbiota is key to healthbut to make good use of probiotics it is important to first understand their real mechanism. And that’s where things get complicated. Years of warning. The problem with probiotics is not that they never work. The thing is that we have turned them into a general use resource, something that is taken preventively and continuously, without diagnosis, without medical indication and without understanding what is really happening in each person’s intestine. A product with real and very specific benefits that social networks have turned into a universal solution. Dammam explains it clearly: Probiotic supplements purchased without a prescription are not sufficiently regulated. You don’t really know what you’re taking. Products vary greatly in labeling accuracy, presence of adulterants, and legitimacy of their claims, according to VA Program documents. Prescribing probiotics is difficult even for doctors: there are thousands of products on the market, each claiming superiority over the other. Many have “special recipes,” proprietary strains or combinations of multiple organisms that the VA wryly describes as “a microbiological shotgun approach.” The problem, ultimately, is not just the lack of regulation. It’s that we start from a wrong premise. The science behind. Dr. De la Puerta, an expert in microbiota, sums it up with a phrase that does not leave much room for interpretation: “If you want a healthy microbiota, you probably don’t need to live taking probiotics.” He said it in podcast by Dr. José Abellán in one of the most shared analyzes of intestinal health in recent weeks. Her central argument is not that probiotics are useless—in fact, she herself admits that she uses and prescribes them frequently—but that they are becoming a permanent habit when they are designed to be a one-time tool. “You have to take them to get you out of a place,” he explains. And he gives his own case as an example: “My microbiota is fairly good, but I have a lot of stress. So I take probiotics from time to time.” The key is in those two words: seasons. Deeper investigations. The latest science backs up exactly this nuance. A review published in Trends in Microbiology concludes that the composition of the microbiome varies greatly depending on geography, age and lifestyle, which directly calls into question the efficacy of universal probiotic treatments and requires that the design of any effective probiotic takes into account microbial diversity and specific adaptation to the context of each host. The Probiota 2025 conference, held in Copenhagen, confirmed this same idea: Geographic and demographic variations reveal microbiome profiles so different among healthy populations that it is impossible to define a universal standard of a “healthy microbiome.” There is another equally serious problem, which Dr. De la Puerta points out precisely: not all probiotics are the same, even if we sell them as if they were. “Take a probiotic, stabilizer, immunomodulator, neuroactive, high load, low load, monostrain, multistrain…”, he lists. Some have more to do with the immune system, others with digestive health, others with mood. The most successful interventions are those informed by a microbial profile prior to treatment, which allows predicting therapeutic efficacy. “That’s why it doesn’t make much sense to buy them at random simply because someone has recommended them on social networks,” the expert details. The garden already planted. There is a conceptual error that lies at the bottom of this entire debate. We take probiotics as if the intestine were empty land waiting to be repopulated. But in the vast majority of healthy adults, the intestinal ecosystem is already established and has its own defenses. According to the VA Programcontinuing to take them once a healthy intestinal ecosystem is formed would be like planting an already planted garden. The real problem, … Read more

In Spain, insurers and venture capital are discovering what the business of the century really is: pets

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It’s nothing new. Statistics have long confirmed a reality that anyone can see walking around their city: in Spain there are more pets than small children. many more. And in view of how they evolve the birth rate and the animal census of company, everything indicates that this gap will widen with the passage of time. It is therefore understandable that insurers are increasingly interested in a business that promises a notable growth in the coming years: policies for dogs and cats. It makes sense if we take into account that in Spain there are not only millions of pets. It is increasingly easier to find families who dedicate hundreds of euros in your care. The number: 20 million. It is not easy to specify how many pets are there in Spain. The figures handled by public organizations, veterinarians and the industry dedicated to their care do not completely coincide, but the general image they offer is the same: we Spaniards like the company of dogs, cats, parrots, ferrets, iguanas and other animals capable of adapting to living in our homes. If we trust Anfaac, the association that represents feed manufacturers, in Spain there are more than 20 million of pets, especially dogs (6.9 million). The Spanish Association of Industry and Commerce of the Pet Sector (Aedpac) raises the number of pets to 28 million“present in 40% of the homes” in the country. Other sources point to some 30 millionwhile REIAC (Spanish Network for the Identification of Pet Animals) had registered three years ago 10.1 million of dogs and 968,000 cats. A question of censuses… and euros. Censuses show us that hundreds of thousands of dogs, cats, ferrets, reptiles, birds live in Spanish homes… but that is only part of the ‘photo’ that interests the sector. Another (equally or even more important) is how much we spend on their care. That question was answered in March by EAE Business School, which published a report on ‘pet-money’ which concludes that pets generate a business of 5,770 million euros annually in Spain, drive an economy that grows at 8.3% and support 75,000 direct jobs in 12,300 companies. These are compelling figures, but they are less surprising when you know another key provided by EAE: 49% of households Spaniards live with at least one pet, on whose care we spend on average between 500 and 1,000 euros per year. “In many cases these disbursements are comparable to spending on leisure or communications,” confirms the studywhich has detected a “cultural change” in the relationship with animals that leads a good part of Generation Z and millennials to affirm that they are an essential part of their lives. “Hundreds of millions a year”. The report from AEA Business School also probed the animal-specific insurance business and discovered two things. First, it is in full expansion. Second, that sector data show that it already moves “several hundred million euros a year.” He is not the only one who paints a promising picture for insurers willing to exploit this business niche. Fortune Business Insights calculate that the size of the global pet insurance market amounted to $25.91 billion last year and, if its forecasts are correct, this year it will rise to $30.74 billion. The organization estimates that the sector is growing at a compound annual rate of 18.63%, meaning that in less than a decade it would be in 120,560 millionwith a prominent weight from North America. A business to exploit. Despite all of the above and the fact that veterinary coverage is basically private, the pet insurance business still has a lot of room to grow in Spain. At least that’s what it suggests a study from Guidewire, which points out that only half of pet owners have a specific policy for themselves. Specifically, after interviewing more than 4,000 people from Spain, France, Germany and the United Kingdom, the firm assures that, although 74% have a pet, only 49.6% have insurance to protect them. Other analyzes on the subject considerably reduce that percentage. “This data draws attention when taking into account the regulations in force in Spain, so, since September 29, 2023, the Animal Welfare Law requires all owners of dogs, the most common pet, to take out civil liability insurance, regardless of their breed,” points out the entity. All in all, Spain is one of the countries “”with the greatest acceptance of pet insurance” and the penetration of this type of services has clearly grown in recent years. Waking up appetite. In view of all the above, it is much better understood that large insurance companies and venture capital is entering in the digital veterinary insurance niche. Their hook: to make healthcare for dogs, cats and other pets easier on the wallet. One of the most recent tests comes from Petolo, linked to Getolo GmBH and the Zurich Group. A few days ago the company announced his landing in Spain after acquiring a portfolio of more than 150,000 dogs and cats insured in Germany and France. “The Spanish market has 15.5 million dogs and cats, mostly without veterinary insurance,” says the firm, which offers several plans that allow you to recover part of the bills (between 60 and 100%, depending on the bread) for animal health care. Is it a unique case? Not at all. As explained recently Five Days There are more examples of insurers and private equity firms that seem interested in the veterinary insurance business. Another recent case is that of Reale, which has decided to reinforce its presence in the pet policy sector. entering the shareholding from Canitas. The business has also attracted entrepreneurs such as those who have promoted the startup Barkibuwhich aims at the same objective: the vein that represents private healthcare for pets. Images | Olga Kononenko (Unsplash) and Karsten Winegeart (Unsplash) In Xataka | We have been looking at Noah’s syndrome as a minority and controlled problem for years. we were wrong

If the question is what is the worst job in history, the answer is in 18th century England: the “sin eaters”

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Have you had a sinful life, full of vices and excesses, but you don’t want that to condemn you to eternal fire? No problem. You just have to make sure that, once you die, your family hires a ‘sin-eater’, a freelance that a small feast will be given on your coffin on the day of your funeral. A term will take with it all the faults you committed in life, no matter how serious or reprehensible they may have been. The ‘sin-eater’ charged for his services, of course, but… How much would you (or your family) pay for eternal life? It sounds strange, but the job of sin-eater It existed centuries ago in some regions of Great Britain. In fact, the newspaper archive allows follow his trail until the 19th. Sin Eaters? Exact. And it’s not a metaphor. Natalie Zarrelli, from Atlas Obscura, calls him “worst freelance job ever” and you’re probably right. The no eater (‘comesins’ or sin-eaters) were just what the word indicates: people who fed on the faults of other people who had died suddenly, without time to expire their guilt. They did not do it out of hobby or because they followed an elaborate (and dismal) medieval diet based on sacrilege, but because that was their job. He no eater He arrived at the wakes, participated in a ritual to free the deceased from his sins, and then left silently with a few coins in his pocket. Where did it exist? There is not much information about them, although references can be found in works such as ‘Brand’s Faiths and Folklore’ either ‘Hill and Valley’an essay published by Catherine Sinclair in the 19th century. In recent years, media articles such as Atlas Obscurathe platform specialized in religion Aleteia or (more recently) the magazine National Geographic. The writer and teacher Megan Campisi He also researched it for his novel The Sin Eater. Thanks to them we can obtain some glimpses of this ancient craft, which took shape centuries ago in Great Britain. And when did they exist? The ‘sin eaters’ worked mainly in certain regions of England, Scotland or Wales and their trade continued with ups and downs since at least the 17th century (some they go back even furtherassociating it with a heritage from the Middle Ages) until the end of the 19th century. In fact there is some reference to a no eater who died already at the beginning of the 20th century and his grave can still be visited today. His figure was based on a mixture of superstitions, paganism and Christianity, all against the backdrop of the religious changes that England experienced starting in the 16th century. In fact there is who slides that its role may have arisen in an attempt to recover popular traditions after the Anglican Reformation. What exactly were they doing? The ‘sin-eaters’ were the central figure of a relatively simple ritual that sought to erase the guilt of the deceased. The family of the deceased placed a piece of bread and a bowl of beer or milk on the chest of the corpse and then called the no eaterwho only had to do one thing: sit before the corpse and eat and drink the food that was supposed to have absorbed the sins of the deceased. A simple gesture with which they made other people’s stains their own. How did they do it? “He would sit facing the door. They would give him a fourpence piece, which he would put in his pocket; a crust of bread, which he would eat; and a bowl full of beer, which he would drink in one gulp. After this, rising from his stool, he would pronounce, with a serene gesture: ‘the peace and rest of the departed soul’, for which he would pawn his own soul.” relates a work published in the 19th century. After the mediation of the ‘sin-eater’, the deceased was supposed to be free of reproaches that could condemn him to hell. Of course, the opposite happened to him: those faults of others ended up weighing on his spiritual record. Was it bad business? It is assumed that the majority of the sin-eaters were humble people, with few resources, for whom a new day of hunger represented a much worse prospect than a supposed eternity of damnation in the flames. Although they only received a few coins in exchange for their work, the job was quite painful. And not only for religious reasons. Some versions They maintain that, by ‘devouring’ the sins of others, the no eater went on to become an outcastsomeone who blurred his soul. Was it that serious? Yes. A ‘sin-eater’ who is not very religious, atheist or even ‘infidel’ might not care too much about participating in the ritual in exchange for a couple of coins, a loaf of bread and a bowl of beer, but he knew that his work would entail an extra sacrifice: the “manifest contempt” from his neighbors, for whom he became a kind of pest, someone to avoid. The families requested his services, invited him to their homes, paid for his service and sometimes the no eater He even listened to the confessions of mourning relatives, but once the ritual was over, no one wanted to have him around. What was its origin? Difficult to specify. In her article, Natalie Zarelli remember that some theories relate the figure of the no eater with pagan traditions, others connect it with the medieval custom of nobles paying the poor to pray for their dead and the salvation of their souls. In a way, the ‘sin eaters’ are also related to other deep-rooted traditionssuch as the belief that living relatives can intercede for their dead, the figure of purgatory or the symbolic value of food. When did they disappear? In the 19th century, when Sinclair wrote his book, ‘sin-eaters’ were already on the decline in England, but that does not mean that they had disappeared. His trail can be followed until … Read more

In 1972 Italy wanted to put an entire city in a one kilometer building. Half a century later he is still paying the consequences

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The same year that construction of the Corviale complex began, US authorities began demolition by Pruitt–Igoea gigantic public housing complex that had been presented just two decades earlier as the future of the modern city. The coincidence was almost symbolic: while one country demolished one of its great urban utopias, another began to build a new one. A city within a building. During the 1970s, Italy believed it could solve several urban problems at once. Rome was growing rapidly, peripheral neighborhoods were multiplying and public housing was facing increasing demand. The answer It was the Corvialea gigantic residential structure almost a kilometer long designed to house around 8,500 people. Its architect, Mario Fiorentino, did not simply imagine a block of flats, but a authentic linear city where streets would be corridors, squares would emerge from common spaces and daily services would coexist with homes. That vision was intended to demonstrate that architecture could reorganize urban life from its foundations. A utopia that was never completed. The problem appeared before the project was even finished being built. The company in charge of the works went bankrupt in 1982 and many of the essential elements of the original design never came to fruition. The famous middle floor used for shops, offices, services and community spaces was left empty and ended up being occupied by families looking for a place to live. What was to become the social heart of the complex ended up becoming a housing labyrinth improvised. Many of the planned facilities were also never built, leaving the infrastructure that was to turn the building into a self-sufficient city incomplete. When architecture conditions everyday life. Over the years, Corviale began to demonstrate that buildings are not simple containers where people live. Its long corridors, its few entrances, the complex interior circulation and the enormous scale of the complex began to influence the way in which the residents they were related to each other. The elevators are They broke down constantlyforcing thousands of people to travel long distances to enter or leave their homes. The centralized heating system caused conflicts between residentsirregular occupants and administrations on who should bear the costs. Some researchers even described the building as a small town whose governance problems were directly linked to its physical characteristics. From the symbol of the future to the symbol of failure. As the deterioration progressed, Corviale began to accumulate a reputation increasingly negative. For many he became the perfect example of the excesses of urbanism postwar monumental. Its critics described it as a concrete monster, a residential prison or an example of how certain urban planning ideologies had ignored people’s real needs. Illegal occupations, maintenance problems, the presence of criminal activities and institutional abandonment reinforced this perception. for years proposals arose to tear it down completely and replace it with smaller-scale traditional neighborhoods, connected by streets, squares and buildings closer to human dimensions. Giuditto Miele at the groundbreaking ceremony for the Corviale complex The battle to decide your destiny. However, Corviale was never demolished. Unlike many other large post-war European housing estates, managed to survive to demolition attempts. Part of the explanation lies in its increasing symbolic value. What for some was an urban failure, for others represented an unrepeatable piece of Italian architectural history. The building ended up getting heritage protection and became part of the national debate about what to do with the great utopias of the 20th century. The discussion stopped focusing solely on whether the project had worked or not and became a more complex question: how to transform such a gigantic structure without destroying it. Half a century of reforms to correct an idea. The last decades have been marked by an almost constant succession of regeneration projects. International competitions, neighborhood associations, architects and public administrations have tried adapt the complex to current needs. Some interventions have regularized occupied spaces, others have rehabilitated common areas and several seek to recover the pedestrian scale through new public spaces and green areas. No other residential complex in Rome has received public investment so intense and prolonged. The paradox in this case is more than evident: the building that was born to simplify urban life has become one of the most complex regeneration operations in the city. Consequences of a big bet. The story del Corviale It continues to fascinate because it transcends architecture. It is the story of a time that believed that social problems could be solved through great physical solutions and a city that continues to deal with the consequences of that bet. The building, by the way, still standinginhabited by thousands of people and subjected to continuous transformations. For some it demonstrates the limits of grand urban visions, for others, the ability of a community to adapt to an unfinished project. The truth is that half a century later, Rome continues to dedicate resources, time and energy to managing a structure designed to function as a complete city. And perhaps that is the clearest proof that Corviale never stopped being exactly that: a city enclosed within a building. Image | Wikimedia, Umberto RotundoAlessandro Pace In Xataka | In 1970 Japan built homes of the future where each capsule would be replaceable. Half a century later he discovered that no one knew how to repair them In Xataka | The incredible story of the tallest building on the planet that ended up becoming the largest swimming pool in the Soviet Union

Microscopes had been dependent on human operators for almost a century. China wants to change that with AI

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A team of Chinese researchers has presented in Beijing which they claim is the first transmission electron microscopy system in the world capable of operating completely autonomously. Dubbed “Aeye-1”, the device has demonstrated in tests its ability to replace a human operator in all phases of the process thanks to AI. What exactly is it. A transmission electron microscope (TEM) is a tool that has been essential for decades to observe matter at the atomic scale. It is used to develop new materials, energy technologies, industrial chemistry, and has been a key instrument for evolution in science. For almost a century, these devices have always depended on manual handling by a technician, something that in the end ends up giving subjective results and entails certain difficulties in performing quantitative analyses. Why it is important. Aeye-1 makes the leap from “manual operation” to “AI-led autonomous operation”. According to they count its researchers, the system carries out the entire work chain by itself, from transferring the sample to capturing the images and analyzing the data without the intervention of any person. According to Deng Dehuiprofessor at the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences and leader of the project, the system works “like an ‘intelligent eye’ that visualizes the atomic world.” In detail. The development was carried out by the team of Deng Dehui and Professor Liu Wei, in collaboration with researchers from the Shenyang Institute of Automation. Together they have designed the algorithms that allow the microscope to perceive, analyze and control the process independently. To achieve this, they had to overcome many technical challenges, including the intelligent transfer of samples in high vacuum, the autonomous optical adjustment of the image, the precise localization of objects at the nanometer scale, the capture and analysis of images in real time and the coordination of all subsystems at the same time. The figures. According to Deng, image analysis It is more than 300 times faster than manual. To understand the magnitude, two weeks of Aeye-1 operation are equivalent to one year of work of a conventional microscope. In tests with molecular sieve catalysts, the system analyzed an average of 168 samples per day, captured more than 4,000 images per day and automatically generated professional reports with detailed statistics on particle size, dispersion or crystal structure. Who supports it. The system surpassed last Sunday an evaluation of scientific and technological achievements held in Beijing and organized by the Chinese Petroleum and Chemical Industry Federation. The evaluation committee unanimously concluded that it is a “highly innovative technology, the first of its kind in the world and an international leader.” And now what. Those responsible for it expect that Aeye-1 will be able to continuously provide large volumes of high-quality structural data in fields such as energy, industrial chemistry, advanced materials and life sciences. The long-term goal is for this new team to drive a paradigm shift in AI-supported scientific research. It really is a process in which automation through AI can be highly beneficial. We will have to wait to find out if it ends up setting a trend in the scientific world. Cover image | China Daily and National Cancer Institute In Xataka | South Korea has just entered the most exclusive club on the planet. And China and North Korea are not exactly calm

In 1967 a war closed the Suez Canal for eight years. Half a century later, the Strait of Hormuz looks into the same abyss

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When war broke out between Egypt and Israel in 1967, fifteen commercial ships were trapped in the Suez Canal. The captains dropped anchor assuming they would only have to wait a few days for the fighting to end. They were right about the duration of hostilities: it was the Six Day War. However, It took eight years for the canal to reopen. When the ships were finally able to set sail in 1975, only two were still seaworthy. The rest had rusted so much under the desert sun that They went down in history as the “Yellow Fleet”. Almost sixty years later, history rhymes in the Persian Gulf. Ninety days after the war between the United States, Israel and Iran blocked the Strait of Hormuz at the end of February, the most important maritime passage in the world remains closed. Dozens of oil tankers wait at anchor, waiting for a diplomatic agreement that always seems imminent but never arrives. The optimism trap on Wall Street The analyst Javier Blas, in your column for Bloombergexposes the dangerous complacency with which the world is facing this closure. The financial industry operates under an adapted version of Stein’s Law: “The Strait cannot be closed forever because it would cause too much economic damage; therefore, it will reopen soon.” The problem with this logic is that the economy has not yet inflicted the pain necessary to force peace. As Blas points out: For Washington: The war is proving politically cheap. The US economy is riding with quarterly growth of more than 4% and the S&P 500 index is close to historical highs, having risen almost 10% since the start of the conflict. For Tehran: Even as the currency plummets and inflation chokes the population, the Iranian regime has demonstrated for decades an almost inexhaustible capacity to absorb economic punishment when it considers it faces an existential threat. While the mediators seek an agreement in Islamabadinertia maintains the illusion of normality. The market has absorbed the disappearance of about 20 million barrels per day thanks to accumulated inventories and massive releases of strategic reserves. Qero the global tank is emptying. June: The end of logistics inertia If we do not see shortages on the streets it is due to pure physics of transportation: a supertanker moves at the speed of a bicycle. The fuel that the West consumed in the spring left the Gulf before the first missile fell. However, the data They already show the cracks in the system. Global demand fell by 5 million barrels per day in April, the largest consumption destruction since the COVID-19 pandemic. And the blow is already felt at home: Funcas warns thatIf the conflict continues, Spanish inflation will exceed 4% and growth will fall to 1.8%. In addition, the multimillion-dollar extra cost of fuel for airlines such as Iberia or Vueling directly threatens the waterline of Spanish tourism. The real precipice has a date: June. With the arrival of summer, the peak driving season and the massive use of air conditioning will collide with inventories at multi-year lows. Furthermore, a diplomatic reopening it would not solve the physical problem: Clearing the mile-wide Hormuz safe lane would require months of complex naval operations. However, the impact of this crisis goes far beyond the gas pump. As the physical shortage of crude oil becomes undeniable, the most serious repercussions are brewing in the bowels of the global financial system: The fracture of the petrodollar: The unwritten agreement of 1974, which guaranteed security in the Gulf in exchange for crude oil being sold in dollars and reinvested in US debt, is breaking down. Countries like India They are selling their US Treasury bonds to obtain liquidity and pay for much more expensive oil. The bond market: The persistence of energy inflation has skyrocketed sovereign bond yields. 30-year Treasury bonds in the US exceeded 5.15%. The cost of real life: If government bonds yield above 5%, 30-year mortgages are inexorably approaching 7%. This translates into more expensive loans, lower business investment and a paralysis of the real estate market. As several analysts warn, undoing the economic damage from Hormuz could require an induced recession to curb borrowing costs. The bypass of the desert While the world waits, some actors have already given up on Hormuz. United Arab Emirates has accelerated urgently the construction of a gigantic pipeline that bypasses the strait, with the goal of exporting 3.5 million barrels a day directly to the Gulf of Oman by 2027. It is “prudent planning for the worst scenario,” and a clear sign that Abu Dhabi believes the waterway could remain threatened for years. Half a century ago, no one imagined that 15 ships would spend a decade rotting in the sun in Suez for a war that lasted less than a week. Today, the world assumes that the Hormuz crisis will be a temporary blip. But as the days go by, the shock absorbers wear out and the financial markets creak. The oil is simply still waiting in the sea. Image | Photo by Jens Rademacher on Unsplash Xataka | The war in the East has reached an unexpected agreement: one where the US does not discuss Iran’s missiles, bombs or uranium

A medieval poet and some buried trees have just revealed something very strange to us about the 13th century Sun

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At the beginning of the 13th century, the Sun was passing through a solar cycle much shorter than those that exist today, but extremely intense. Having such specific details is complicated for such a distant time, when scientists did not have instruments to measure this type of activity. However, there is something that today’s scientists do have and that has helped them detect this event: a book of poetry and many trees. Art and science. A team of scientists from Okinawa Institute of Science and Technology has described this event using two types of data. On the one hand, a poem written in 1204 by the Japanese writer Fujiwara no Teika. On the other hand, the observation of the rings of buried tree trunks in northern Japan. The conclusion is clear. While today solar cycles are usually around 11 years, back then there were some 6 or 7 years, but the activity was high enough to lead to the formation of auroras in Japan. A proton explosion. When solar activity is very intense, phenomena such as solar flares or the coronal mass ejections. The first is a sudden release of electromagnetic radiation from the solar surface, while the second consists of the expulsion of matter, normally charged plasma particles, from the Sun’s corona. Associated with these phenomena, proton explosions occur, in which these charged particles move at high speed. rare isotopes. Normally, a good part of these charged particles and cosmic rays fail to pass through the Earth’s magnetic field. However, when they are very intense they can reach our atmosphere in greater quantities and interact with the gases in it. In this reaction, isotopes such as beryllium-10 or carbon-14 can be formed. These are beryllium or carbon atoms with a different number of neutrons in their nuclei than the beryllium and carbon that are most abundant on Earth. Knowing this process is useful, because it can give us clues on two levels. On the one hand, beryllium-10 is deposited in ice sheets, while carbon-14 It oxidizes, transforming into carbon dioxide and becoming part of the carbon cycle. In this cycle, living beings incorporate it into their cells in different ways. For example, plants do this through photosynthesis. And this is where what has been so useful to these scientists begins. Solar dating and meteorology. Carbon-14 is often used to date fossils, since they come from living beings that once incorporated that isotope into their tissues. The moment a living being dies it stops incorporating carbon-14. From that moment on, it begins to disintegrate at a known rate, so it can be estimated approximately when it died. The point is that, beyond that, if carbon-14 levels are unusually high, it can also be determined if there was an extreme solar event. The poem describes a dawn The poem. in his diary Meigetsukithe poet Fujiwara no Teika described the observation of “red lights in the sky over northern Kyoto.” This city is at a latitude too far south for auroras to form, but that is clearly what it describes. The auroras They are the result of a type of interaction between the gases in the atmosphere and the charged particles of the Sun that causes the emission of visible light. They are normally formed at the poles, as they are the points on the Earth where the magnetic field is most vertical, so that it acts as a funnel, so that these particles can pass through it. When they occur far from the poles it is because solar activity has been very intense and the resistance normally opposed by the magnetic field has been exceeded. What the trees tell. The rings of tree trunks are a kind of natural calendar. They are formed from the inside out, so we can count them and calculate how the years have passed. For this reason, the authors of the study that has just been published They wanted to analyze the equivalent buried tree rings at the beginning of the 13th century. In the rings from the period from winter 1200 to spring 1201 they found an increase in carbon-14 levels. This also agrees with the levels of beryllium-10 found in ice deposits from that same period. Everything agrees. Also in China. There are historical records from the time when Chinese astronomers also described red lights in the sky. Therefore, it seems clear that there were auroras at unusual latitudes. A very rare case. The most curious thing about all this is that this phenomenon did not occur at the peak of the solar cycle. It possibly took place around its periodic minimum. If there was less activity, why so much aurora and carbon-14? This is something that, at the moment, scientists have not been able to explain. Perhaps there were also many auroras at the peak, but no poet stopped to write about them. Tree rings would have to be analyzed to see what carbon-14 tells us. What is clear is that the Sun was burning in those medieval times. Image | Masaaki Komori (Unsplash)/Wikimedia Commons | Kush Dwivedi (Unsplash) In Xataka | A sunspot 17 times larger than Earth caused red auroras across half the world. It is a very rare event

In the 16th century, Spain wanted to control the Strait of Magellan by founding a city. It became a cursed settlement

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A coin is a coin. And a compass, a compass. What seems so obvious changes when we talk about the old (and ephemeral) city ​​of King Don Felipea Spanish settlement founded more than four centuries ago by Pedro Sarmiento de Gamboa on the northern shore of the Strait of Magellan. Its objective was to become a fortress that would reinforce the control of the Spanish Crown in a strategic maritime passage, but the mission became so complicated that the town ended up becoming a death trap for its settlers. Things went so badly that with the passage of time the citadel ended up being renamed ‘Port of Hunger’a name much more in line with what happened there in the 17th century, and its memory it faded in the mists of history. We had to wait until well into the 20th century so that the secrets of King Don Felipe would emerge from oblivion… and the earth. Now the archaeologists have found among its ruins a small piece of silver that in March 1584 Pedro Sarmiento de Gamboa himself deposited there during the founding ceremony of the town. In its day it was a simple currency (a real of eight) that was used for ritual purposes. In 2026 it has become something more: a compassa guide that will help researchers better understand the structure and location of the city of Rey Don Felipe, the cursed citadel in the Strait of Magellan that should never have existed. At the ends of the world Today the world lives pending what happens in the Strait of Hormuz. Almost five centuries ago the eyes of the Spanish Crown were directed towards another maritime strait with important strategic value: that of Magellana navigable strip located south of what is now Chile and that stands out as the natural connection between the Pacific and the Atlantic. Since Ferdinand Magellan crossed it for the first time, in the autumn 1520the pass became an object of desire for the Spanish Empire, especially after other expeditions managed to cross it successfully and the English entered the race for its control through late 1570s from the hand of the corsair Francis Drake. To guarantee Spain’s geopolitical plans and its exclusive control of the transoceanic passage, the authorities had an idea: found permanent settlements in the area. The mission fell to Pedro Sarmiento de Gamboaa hardworking sailor who, among other missions, had participated in a (frustrated) mission of the Viceroyalty of Peru to hunt down Drake. Sarmiento first undertook an expedition with two ships in the autumn of 1579 to reconnoiter the coastline of the strait and explore its coasts and, once back in Spain, in 1580 he played a decisive role in getting the Council of the Indies to decide to build citadels and fortifications in the transoceanic passage to America. The expedition left Sanlúcar at the end of September 1581 with a fleet of 23 boats and around 3,000 men, including sailors and future settlers. Despite his enormous ambition, the adventure started badly. And not only because of the differences between Sarmiento and Diego Flores de Valdeswho had been appointed captain general of the Strait Navy. Before even leaving Cádiz, a storm sank half a dozen ships and killed 800 men. What followed next was a journey marked by disagreements between Sarmiento and Valdés, illnesses, the inclemency of the ocean and storms that caused the expedition to lose ships, crew and supplies. After various incidents and vicissitudes, Sarmiento and his men arrived at the strait at the beginning of 1584 and founded a city that they named ‘Purification of Our Lady’. It didn’t work. The location and climate did not help, so Sarmiento looked for a new enclave, near Cape Vírgenes, and founded a settlement which he called ‘Name of Jesus’. Determined to continue with the mission, the sailor chose part of the 340 people he kept and looked for a third location to create another citadel. On this occasion he baptized it with a nod to the Habsburg court (King Don Felipe) and celebrated the founding ceremony in March 1584. We know that Sarmiento himself participated in the ritual. On March 25, he laid the first stone of the citadel church and, with it, in the foundations, buried a real of eight silver. As they explain from the Bernardo O’Higgins University of Santiago, it was “a symbolic gesture that marked the birth of the city.” If the ritual was intended to promote the settlement’s fortunes, it only half worked. It has served archaeologists of the 21st century, who have just found the coin “in place and position” described by Sarmiento in his writings and now, thanks to that clue, they will have an easier time interpreting a map of the 16th century in which the buildings of the town are represented. The one who certainly had no use for the currency was the colonists who settled in Rey Don Felipe city. Theirs was a tragic story from the beginning. a cursed city Ciudad Rey Don Felipe may have enjoyed a privileged location from a geopolitical and strategic point of view, but the truth is that it soon became hell for its settlers. And not only because the crew of the ill-fated (and diminished) Armada del Estrecho arrived in Magallanes at the limit of their strength. In ‘Port of Hunger. Beyond the legend’a work signed by the historian Soledad González and the archaeologist Simón Urbina, a key piece of information is provided: “On board the ships or on land they saw people die or desert. nine out of ten colleaguesfriends or family. As if that were not enough, after founding the Nombre de Jesús settlement, the crew divided into groups to expand towards the Santa Ana peninsula, precisely to establish Rey Don Felipe. Once there, and despite the fact that Sarmiento de Gamboa was quick to lay the foundations of the new citadel (both in a metaphorical and literal sense), things did not improve. The scene looked so bad … Read more

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