Predicting Alzheimer’s 10 years in advance is now a scientific reality. The challenge now is to prevent healthcare from collapsing

Alzheimer’s is a devastating disease that is undoubtedly a true ghost, since it only It becomes visible when the damage is already irreparable and that, despite trying to stop it, it is becoming difficult to control it. And historically, the medical diagnosis comes when memory begins to fail, but by then the brain has been suffering in silence for years, even decades. Now science focuses on the need for early diagnosis so that treatments can work. A new analysis. One of the ways to detect this disease before it begins to show the classic symptoms such as memory loss is through a blood test. This is the milestone that has been collected in The Lancet magazine recently thanks to research from the University of California, and that could generate a large population screening that is not free of controversy. What they did. The researchers followed 1,350 people aged between 56 and 69, without any type of dementia, for more than 35 years. And here the key was to look for specific proteins circulating in the blood that increased in the earliest phases of Alzheimer’s, as occurs with others marked in other diseases such as PSA in prostate cancer. And they found two biomarkers. The first of them is Aβ42/40, which is an early indicator that warns of the accumulation of hateful beta-amyloid plaques in the brain. But they also found the protein p-tau217, which is considered today the most precise marker for the pathology. The results. The 6% of participants who tested positive for these biomarkers showed a four-fold increased risk of developing verbal memory problems and a decline in their cognitive speed a decade later. But science has been trying to refine this tool for years, looking for markers such as GFAP, which rises about ten years before symptoms appear. See the invisible. The blood test does not walk alone in this diagnostic revolution, since on the same day, The Lancet published a second study based on nearly 800 participants from the US and Canada that tests a new and sophisticated neuroimaging technology: the MK6240 PET plotter. Until now, visualizing the tau protein, which is one of those responsible for Alzheimer’s by accumulating in neurons, was a great challenge. But this new tracer promises to be much more sensitive, detecting twice as many positive cases in healthy people with amyloid accumulation compared to the standard used today. You have to wait. Before throwing the bells in the air, it should be noted that experts point out that this test not ready to be used as general population screening. The reason lies in mathematics, since the prevalence of asymptomatic Alzheimer’s in healthy middle-aged people remains low in absolute terms, so applying this test to everyone would generate a very high volume of false positives. That is, an increase in this protein that is not actually related to early Alzheimer’s. But logically, the fear, anxiety and the resulting cascade of confirmatory tests would collapse the health services that are already stressed, and furthermore, the drugs we have, despite the fact that they stop the effects of the disease in its earliest phases, are not yet definitive. That is why we must remain on the right path, but there is still a long way to go to get this disease under control. Images | Robina Weermeijer Testalize.me In Xataka | Alzheimer’s no longer seems irreversible: science allows brains with advanced damage to recover for the first time in animals

Francisco Valencia, CEO of Secure&IT, on the challenge of AI attacks

Yesterday morning I went to a new edition of the cybersecurity conferences of Secure&IT in Madrid with a fairly clear idea: to listen to how companies are using the artificial intelligence to better defend yourself and make life difficult for cybercriminals. It was a reasonable expectation. AI has become one of the great promises of the sector and it seemed logical to think that a good part of the conversation would revolve around its new defensive capabilities. But the day left a much deeper reading. What is moving is not just another technological layer on top of the usual systems. It is the mental framework of cybersecurity itself. The speed of change, the sophistication of attacks, and the entry of new algorithm-based tools are forcing companies to rethink everything from how they patch software to how they anticipate threats. The feeling there, listening to the speakers, was clear: we are not facing a simple update of tools, but rather a change of era. Francisco ValenciaCEO of Secure&IT, who I was able to interview a while agoput that idea on the table as soon as it began with a particularly graphic phrase: “We have always said that in cybersecurity we are one step behind cybercrime and we are now 10 steps behind cybercrime“The statement was surprising for its crudeness, but it also helped to organize the conversation. Looking at this disadvantage head-on, without selling false certainties, may be the first step to understanding what is coming. Cybersecurity was waiting for an ally, but cybercrime has also found one The key is that AI has not only changed the available tools, but also the balance of the game. Valencia put it crudely because, from his point of view, cybercriminals have taken off while many companies are still trying to decide how to use AI in a safe, useful and governed way. This difference in rhythm explains a good part of the diagnosis. Attackers don’t need to resolve every internal debate in an organization, justify every deployment, or wait for a perfect corporate policy. They just need to test, automate and exploit what works. The speaker began by addressing one of the most disturbing pieces of this new scenario: the Dark LLM. LLMs, or large language models, are the technical layer that powers applications such as ChatGPT, Copilot or Gemini: systems capable of interpreting instructions, helping to program or solve complex tasks. The companies that develop them introduce limits, filters and guardrails to prevent harmful uses, both for safety and for the ethical criteria with which they design these systems. The Dark LLM, such as FraudGPT and WormGPTstart from a much more dangerous logic: offer similar capabilities, but without those barriers. The interesting thing is that this logic does not always depend on creating a new model from scratch. Valencia also spoke of jailbreaka way of trying to avoid the limits of conventional AI through carefully constructed instructions. It’s not simply asking a system to do something forbidden, but wrapping that request in a context that pushes it to respond where it should stop. In practice, the result can be similar: capabilities of a powerful model put at the service of uses that large companies try to block. This leap is very well understood when we move from the tool to deception. For years we have associated many fraud campaigns with clumsy, massive and easy-to-detect messages, but AI allows us to change the scale without giving up personalization. The CEO of Secure&IT summed it up with a very clear phrase: “I don’t need to send the Nigerian’s spam to 20 million people saying that I have fallen in love with 20 million people to see who will bite. I send the same email to 20 million, but I tell each one what they want to hear“That’s the difference: the attack can still be massive, but it no longer has to seem generic. The attack may still be massive, but it no longer has to feel generic. During the presentation a term also appeared that caught my attention: malware polymorphic. It may sound very technical, even more typical of a conversation between analysts than an article to understand what is happening, but it helps to land something important. We are no longer just talking about a malicious program that enters a computer and tries to repeat itself on other computers with the same behavior. It is something much more sophisticated: a threat capable of reaching a machine, reading the environment, identifying what defenses are in front of it and generating a version adapted to that specific scenario. The consequence for security teams is obvious: if each machine receives a different variant, detecting patterns, relating signals and reconstructing the attack becomes much more difficult. It is no longer just a matter of finding a malicious file and following its trail across the network. In a scenario where “the virus on each computer is different“, the campaign can have the same objective, but leave different traces on each team. And when the traces change, the analysis is no longer linear. Secure&IT dedicated its cybersecurity days this year to analyzing how AI is changing the sector Valencia’s message about automation was one of the clearest of the day: AI is taking time away from defense. For years, companies have had some margin between detecting a vulnerability, creating an exploit, and actually exploiting it. That margin could be imperfect, but it existed. It allowed you to organize analysis, prioritize patches and update systems every certain number of months. The phrase that best condenses the change is direct: “Until now time was a weapon to defend ourselves and now time is no longer a weapon to defend ourselves.” The consequence is very practical. If before an organization could carry out vulnerability analyzes every several months and plan updates with some calm, that scheme is beginning to fall short. According to experts, an AI tool can search for a vulnerability, identify it, prepare the attack path, and run it … Read more

Zeekr comes with the very complicated challenge of breaking prejudices. You have reason to believe it

When someone asks me, I am very clear about where I think Chinese brands can hurt Europe: the “cheap” car. I put the latter in quotation marks because it’s not just about cars under 20,000 euros, I also think they have a chance in that type of product that gives a lot for less money than its rivals. Although, in that case, we are already talking about figures close to 50,000 euros. but there are some nuances here. It is clear to me that the bulk of sales of Chinese manufacturers in these first years They will arrive with models with a combustion engine. Either because they can make volume in markets like Spain, with a high rate of sales of low-end vehicles or because, due to the particularities of the tariffs imposed by the European Union, they offer very competitive cars in the triangle formed by price, equipment and electric range. Yes, I have more doubts in the electricity market. First, because these cars are subject to tariffs, which makes it difficult for them to compete on price. Secondly, because European manufacturers are starting to get their act together -heh- and the offer in all types of sizes, range and price is already more than interesting. Third, because the more the price of the car rises, I have the feeling that the customer takes less risk and the more he values ​​staying with the “old-fashioned” brands. Zeekr will play in a very complicated league. And yet, he has reason to think that he can gradually gain ground. We shouldn’t wait an emergence like that of BYD (four of the 10 best-selling electric cars last year in Spain were theirs) or Omoda/Jaecoo, which are building its sales around cars with combustion engines. I think they themselves are aware of them. But they have the muscle and the product to allow themselves a slow landing but with a view to prospering in the future. “We make exclusivity accessible,” said Lothar Schupet, CEO in Europe, in his presentation. A good starting range Zeekr arrives in Spain in the middle of a new expansive wave across Europe. If we have said that our country has been the perfect gateway for manufacturers who fight over price, the case of Zeekr is completely different. The company has been selling its cars for some time in the Nordic countries or the Netherlands, where electric sales are more advanced. Now it is time to make the leap to less consolidated markets, such as Spain. This has an advantage. The company is already rolling in Europe and has waited until sales have started to pick up more strongly. But they also have other incentives. The range already consists of four cars, of which only one of them will arrive in the coming months. The other three can now be purchased. This range also touches several styles. Zeekr He Zeekr It is a very interesting electric compact. During our contact with the company we had the opportunity to briefly ride it. It is a 4.43 meter car that has three versions. The basic one costs 37,137 euros and has a 49 kWh battery with 272 HP of power. Above there is an intermediate version with 340 HP of power and a 61 kWh battery. The most ambitious reaches 496 HP of power that is combined with a 69 kWh battery. The latter already stretches to 46,242 euros. The first two batteries are LFP and the largest is NCM. The last two steps move between 405 and 415 kilometers of autonomy, which allows you to travel with some peace of mind. The access version is limited to the city with its theoretical 330 kilometers of autonomy It is an agile car that does not feel as soft or as artificial as many other Chinese cars. It is complemented by an interior feel in the materials that is pleasant in general lines but above all with rear seats and a trunk that make it a very attractive proposal for families who move in an urban environment and who take one or two long getaways throughout the year. Despite its 400 volt architecture, it can go from 10 to 80% in just 18 minutes. Furthermore, there is something that I really liked about this car and that is its aesthetics. Its design differs from other Chinese cars that may be more similar to each other and this Zeekr X does seem to me to have a clear and defining image by itself. Above, the Zeekr 7 It is the family model. It is an SUV that is committed to interior spaciousness, especially in the rear seats, and that raises the level in terms of the interior appearance of the materials. It is a car that we were not able to test but it comes with 75 kWh LFP and 100 kWh NCM batteries. ITS 800 volt architecture allows it to go from 10 to 80% charge in 13 minutes and promises 615 kilometers of autonomy in its largest version. Inside, the Zeekr 7X is also committed to offering the best image in terms of quality perception. It is a car that will arrive loaded with technology with the latest active infotainment system, similar in format to what we see in Tesla. It is a car that starts at 52,500 euros with its single-engine (421 HP) rear-wheel drive version. Above, it combines this motor with the large battery, which would be the most balanced option or the longest autonomy (615 approved kilometers), costing 54,425 euros. The jump to all-wheel drive (two engines totaling 646 HP) means increasing the price to 62,250 euros. He Zeekr 7GT It is the car that will arrive in a few months. It is a sportier version with a family or style body. shooting brake. However, it will be a car that is slightly lower in price, starting at 45,675 euros in its cheapest option, with a 75 kWh battery and 421 HP of power and reaching 59,235 … Read more

Ozempic’s great challenge is the rebound effect. Science already has two promising solutions to avoid it

The rise of medications such as Ozempic, wegovy o Mounjaru has completely transformed the clinical and social landscape of the weight lossmaking many people do not hesitate to ask their family doctor to prescribe it in order to lose weight and also regulate blood sugar. The results during treatment are undeniable, but the big question it raises about medical consultations is what exactly happens when the medication is stopped. What we know. One of the most feared points of this type of treatment is the ‘rebound effect’ which causes that, at the time of stopping the treatment and if eating habits have not been adjusted, a large weight gain will be seen. This is something that causes many people to see that this treatment only gives a few months of ‘thinness’, but science is now trying to avoid this effect. The rebound. An exhaustive analysis published in The BMJ finally put exact figures on this phenomenon so that you can speak appropriately to patients. And what has been seen after analyzing 9,300 participants is that patients recover an average of 0.4 kilos per month after stopping treatment. At this rate, the return to the initial weight before starting therapy occurs in just 1.7 years. But this is also accompanied by a loss of cardiovascular shield at 1.4 years. The solution. one of them it involves taking a pill daily known as orforglipronwhich is nothing more than a non-peptide GLP-1 receptor agonistwhich means that it can be taken orally and not through subcutaneous injections. The idea here is to use the injectable treatment, which is more powerful, for the first few weeks and then transition to this daily pill to consolidate the results without the rebound effect. This not only greatly improves patient comfort, but facilitates mass production by not relying on problematic ‘pens’ containing semaglutide, and helps maintain satiety signaling at the brain level without the invasive impact of the needle. A bacteria. The second line of research points to the intestinal microbiome, by analyzing supplementation with the bacteria Akkermansia muciniphila MucT pasteurized as a tool to avoid the rebound effect after a low-calorie diet. A bacteria that is long known in the field of nutrition for its role in the integrity of the intestinal barrier. After doing the analysisit was seen that the group of patients who received the bacterial supplement recorded a weight recovery of only 13.6%, compared to 32.9% in the control group. But beyond the scale, it has been seen that this bacteria shows a notable preservation of insulin sensitivity, a crucial factor to avoid the development of type 2 diabetes and keep lipid metabolism under control. The future. We are undoubtedly at the beginning of a paradigm shift, since the medical narrative is moving from the short-term “war against kilos” to chronic and sustainable management. But logically, for this to reach the market, we must wait (and not a little) for better results and above all for it to be tested in humans. Images | stefamerpik in Magnific In Xataka | We thought Ozempic was only for weight loss. Science is seeing that it can end alcoholism

Your real challenge is to make us change our habits.

On May 18, Bizum will activate payment in physical stores via NFC: you bring your mobile phone close to the dataphone and that’s it, just like with Apple Pay or Google Pay. No PIN, no card and no cash. A platform with 31 million users in Spain takes the leap that makes it a direct competitor of Visa and Mastercard at the physical point of sale. The problem is that banks and businesses want to make that leap. The consumer, at the moment, has no compelling reason to move. Why it is important. For ten years, Bizum has only generated costs for banks, which have invested a lot of money in creating and maintaining it. The jump to physical commerce changes that equation: businesses will pay a commission for each transaction, as they already do with cards, but predictably lower as international intermediaries disappear. There is the business that Spanish banks have been waiting for for a decade. And businesses also win: they get paid instantly, compared to 24-48 hours for traditional card settlement. The user, on the other hand, pays exactly the same as before. Just with another environment. In detail. The gesture will be identical to today’s contactless card: you bring your mobile phone close to the dataphone and in seconds it is done. The user can do so from their bank’s app (which will incorporate the functionality) or from Bizum Paya new digital wallet available on Android and iOS that works similarly to Apple Pay or Google Pay. The difference compared to paying with a virtual card in the wallet is that money travels as an instant transfer from account to account. Some details: Businesses will not have to change their dataphone: it will be enough to update the terminal software. Bizum Pay will allow you to add a bank card as a backup method: if the payment fails, the system automatically changes without you having to swipe your mobile again. The big question. Why would someone who already pays without any hassle with their card, or with Apple Pay, or with Google Pay, change their habit? Inertia is the silent enemy of any new payment method. And in this case it is huge. The most logical answer is incentives: cashbackdiscounts in specific establishments, or any mechanism that makes the user feel that the change is worth it. The data of the ecommerce point in that direction: when Bizum eliminated the friction of entering card information in online stores, users quickly adopted it and today it is the second favorite payment method for buying online, with a share of 20-30% (which is not bad, but it is not something to write home about either). The equivalent in the physical world is yet to come. Yes, but. May 18 won’t be the big launch the date suggests. CaixaBank, Sabadell and Bankinter will go in the first wave, Santander will delay its incorporation to the fall. The massive deployment, including a campaign, is expected in September or October. And that Mercadona is already negotiating advantageous commissions before the service starts says a lot about where this battle is really going to be fought. Go deeper. What is at stake goes beyond Spain. Bizum is negotiating with equivalent platforms in Italy, Portugal and the Nordic countries to build a European payments system that could reach more than 130 million citizens. The business model established in Spanish stores this year will be the template on which this continental project is built. In Xataka | The Treasury has its eye on Bizum, Wallapop and Revolut. Don’t panic: it’s your update in the new digital economy Featured image | Xataka with Mockuuups Studio

The US is using an exascale power supercomputer to solve the biggest challenge of nuclear fusion

The Frontier supercomputer at the Oak Ridge National Laboratory (ORNL) linked to the US Department of Energy is one of the most powerful on the planet. In fact, it is currently the second most capable exascale supercomputer after El Capitan according to TOP500 ranking. These machines are very valuable tools that are already being used by researchers to try to solve some of the most complex scientific problems that humanity faces. And one of them is the behavior of plasma when it is under the influence of a magnetic field. A group of ORNL researchers is using two of the most powerful tools currently available to humans, the Frontier supercomputer and the artificial intelligence (AI), to understand with the greatest possible precision the chaotic behavior of the plasma of stars. An important note before moving forward: plasma is an extremely hot gas made up of particles endowed with an electrical charge, which is why it can be confined inside a magnetic field. This knowledge can presumably help scientists very accurately simulate the supernovaswhich are nothing more than the explosions that occur when a massive star loses hydrostatic balance by burning most of its fuel. When a supernova is triggered, a good part of the chemical elements that the star has produced through chemical reactions nuclear fusion It shoots towards the stellar medium with a lot of energy. From supernovae to experimental nuclear fusion reactors Dr. Eliu Huerta, a computational scientist at the Argonne National Laboratory (USA) who has had the opportunity to supervise the work of the ORNL researchers, express clearly why this scientific initiative is so important: “This type of capability has long been the dream of astrophysicists and many other scientists. This is the first time that this level of understanding has been achieved through AI for systems of this complexity (…) The more chaotic the system, the more difficult it is to simulate it.” Understanding very precisely how the plasma of stars behaves is important not only to have more information about supernovae; It is also crucial for predict solar flaresor even to simulate the interaction of the Earth’s magnetic field and the high-energy ionized atomic nuclei that constitute the cosmic radiation. Frontier’s role in this research is critical: it provides the computational power required to train the models needed to generate thousands of detailed plasma simulations. Inside nuclear fusion reactors it is still a challenge to keep turbulence under control However, there is another application in which this technology has the ability to make a difference: the development of nuclear fusion reactors. We can intuitively imagine a nuclear fusion reactor as a pressure cooker in which two essential ingredients are cooked: deuterium and tritium. In order for the nuclei of these two hydrogen isotopes to fuse and release the neutron that will ultimately allow us to obtain a large amount of energy, it is necessary to confine them in an extremely hot plasma. In fact, for this process to take place it must reach a temperature of at least 150 million degrees Celsius. Scientists know how to do it, so subjecting deuterium and tritium nuclei to the pressure and temperature necessary to make them fuse is no longer a problem. What still represents a challenge is to achieve keep turbulence under control. Otherwise the plasma will be destabilized, its density in critical regions will be affected and sustaining the fusion reaction over time will not be possible. The mechanisms that govern this process are very complex, but little by little physicists and engineers working on fusion energy are managing to understand them better. The research of ORNL scientists seeks to better understand the behavior of plasma confined inside the vacuum chamber of experimental nuclear fusion reactors with one purpose: to minimize turbulence so that energy loss is minimal. And they are on the right track. In fact, they already have a system ready that is capable of delivering very detailed turbulence predictions in just a few seconds, thus reducing errors by more than half compared to previous methods. Image | Fusion For Energy More information | ORNL | Interesting Engineering In Xataka | ITER has faced one of the great challenges of nuclear fusion: preventing plasma at 150 million ºC from destroying the reactor

As we look to the Middle East, the Arctic has become the hiding place for Russia’s biggest challenge to NATO: Borei and Yasen

One of the greatest fears of Western navies was not a direct attack, but something much more disturbing: not knowing where the opponent was. That feeling became especially evident when, in the middle of the Cold War, a Soviet submarine managed follow a naval group American for days without being detected, demonstrating that in certain scenarios the true power is not in striking first, but in remaining invisible long enough. It is not seen, but it does not stop. They had an extensive report in Bloomberg that, hundreds of meters under a mountain in northern Norway, NATO relentlessly monitors a dashboard that does not appear in the daily headlines, but has never stopped being active. While global attention focuses and rightly so most visible conflictsin the depths of the North Atlantic there is a constant competition to detect, follow and keep track of the adversary’s most sensitive assets. It is, if you will, a silent, technical and permanent surveillance, one where the margin of error is minimal and where the absence of news does not mean, by any means, absence of activity. The Arctic as a strategic epicenter. As we said, although the political and media focus has irremediably shifted to the Middle Eastthe real pulse between Russia and NATO is moving further and further towards the arcticthousands of meters under the sea in an environment that combines isolation, depth and extreme conditions that make any monitoring difficult. This region, which for years was seen as peripheral, has regained its centrality for the opening of new routes, resources and, above all, for its military value as a transit and concealment space. In this scenario, ice and geography, more than obstacles, are natural allies for those who know how to take advantage of them. AND Moscow has the advantage. Welcome ceremony for the Borei K550 class nuclear submarine “Alexander Nevsky” at the permanent base in Vilyuchinsk Borei and Yasen: the Russian challenge. The heart of this strategy is the new generation submarines deployed by Vladimir Putin, especially the classes Borei and Yasendesigned to operate for long periods without being detected and capable of carrying strategic weapons. While they don’t always match their Western counterparts in stealth, they remembered in Bloomberg They compensate with tactics adapted to the Arctic environment, such as operating under the ice sheet or protected by other units, which greatly complicates their location. Perhaps for this reason, for NATO the greatest risk is not their presence, but rather the moment in which they are no longer under control. K-560 Severodvinsk A constant chase. It we have counted before. For decades, the key point to detect these submarines was the well-known GIUK runnerbetween Greenland, Iceland and the United Kingdom, but technological and operational advances have pushed this hunting species towards higher latitudes. Now, the objective is to intercept them before they abandon the relatively shallow waters of the Barents Sea and enter areas where they can disappear more easily. This evolution has forced to strengthen cooperation between allies now deploy surveillance systems increasingly sophisticated. Europe in the shadows. It happens that, in the face of uncertainty Regarding the long-term commitment of the United States, European countries are increasing their involvement in this surveillance, with Norway as a centerpiece and partners such as the United Kingdom, Germany or Canada, strengthening capacities and coordination. The result of this has been translated in new acquisitionsjoint exercises and advanced deployments, all movements that reflect a transition in which Europe tries to assume more responsibility for its own defense, especially in an environment as critical as the Arctic. A new Cold War under the ice. Yes, because the result brings us closer to a scenario that increasingly reminds us of the (il)logic of the Cold War, but this time with the difference that now there are much more advanced tools and a geopolitical context. completely different. The russian northern fleetmodernized and prioritized within its military structure, represents one of the Kremlin’s main deterrence capabilities, especially as its conventional forces show weaknesses on other fronts. And in that unstable balance, the Arctic seems to consolidate itself as a lucky “perfect hiding place”a place where Russia’s greatest challenge to NATO is not announced, it is simply happening under the cold sheet of ice. Image | NDUP, Mil.ru In Xataka | A nuclear giant designed to make way in the Arctic: this is the most modern icebreaker in the Russian fleet In Xataka | Russia and China already had an advantage over the US in the Arctic. After Greenland, it has multiplied

We were going to turn trash into clean energy. Now the biogas sector faces its biggest challenge: convincing neighbors

Spain may be emerging as great power in solar and wind energybut there are other green energies that choke him. The Spanish state is not having a nose for biogas. Or rather: it doesn’t smell good, in the most literal sense of the word. However, the sector has practically gone from zero to one hundred in record time: in just two years there are more than 200 biogas projects on the table in different processing phases. And they bring with them a problem: biogas is the green energy that no one wants close to home. The problem: energy transition vs. social rejection. In the roadmap for Spain’s energy transition (the PNIEC 2030), whose ultimate goal is for the state to achieve emissions neutrality by 2050, biogas has its role. But to make it possible, it is an essential requirement to build and launch plants. And here it collides with a wall of social rejection in the form of citizen platforms, not so much to the technology itself, but to the implementation model. There are no shortage of reasons: from the classic fear of bad smell to the lack of territorial planning, promoter companies that present projects without setting foot on the territory and talking to those who live there, the gigantism of some facilities or the shadow of macro farms as arguments, such as They explain for El País the emeritus professor of Environmental Engineering at the Polytechnic University of Catalonia Xavier Flotats and the biologist and researcher at the National Museum of Natural Sciences Fernando Valladares. Why is it important. That biogas appears in Spain’s energy transition strategy implies that, sooner or later, it will materialize; the key now is in the as. It is also a direct path to energy sovereignty that replaces natural gas. Just take a look at the electricity price map in Europe To understand it: countries that depend on imported fossil fuels suffer from price volatility, while those who have opted for their own alternatives They achieve greater independence and stability. But its value goes beyond energy. These plants generate organic fertilizers that replace chemicals derived from petroleum and offer a real solution to waste management. The slurry or agricultural remains will be produced the same, with or without a plant; The difference is that biogas allows them to be turned into a resource instead of leaving them as an environmental problem. Context. A biogas plant is essentially a stomach where bacteria break down organic waste without oxygen, known as anaerobic digestion. From here two products are obtained: a gas rich in methane and a fertilizer. Depending on the gas obtained, the plant is simply biogas or biomethane: biogas is methane combined with carbon dioxide in almost equal parts, so it is a “weak” fuel that is usually burned on site to generate electricity or local heat. However, biomethane plants add a refining step (removing carbon dioxide) to obtain a gas similar to fossil natural gas. In Europe, the biogas sector is a consolidated industry with more than 19,000 plantsof which almost half are in Germany. A picture says a thousand words: this Europe biomethane plants map of Gas Infrastructure Europe shows the density in states like Germany or Denmark compared to the Spanish desert. The ecological dilemma. For engineer Xavier Flotats, the general rejection is a contradiction: “For some activists, it is better that a landfill is emitting methane into the atmosphere than taking the waste to a biogas plant to do something useful with it.” And he goes deeper by explaining that although this outgoing digestate has 95% of the input composition by weight, its composition changes, it is mineralized and converted into fertilizer. Valladares assures that biogas plants are greenwashing in that the process does not make the waste disappear, they only remove 5%. And that “Biogas plants cannot be understood without the macro farms industrial poultry, pigs and cows.” For the biologist at the National Museum of Natural Sciences, the only viable plants are few, small, safe and expensive. Marina Gros, representative of Ecologistas en Acción recognizes that “There are discrepancies within the organization because there is debate, there are different visions.” And in fact, have published a guide to evaluate case by case. The elephant in the room. Beneath the biogas dilemma inevitably lies the controversy of macro farms: In the event of a possible deployment of plants, the reality would be that part of the biogas produced in the state would depend on its slurry. There are those who see this as taking advantage of an already existing problem, but for other people it represents a facelift to a type of industrial livestock farming designed to maximize productivity at a lower cost compared to animal welfare and the environmental balance of the territory. Separate the wheat from the chaff. Faced with this flood of projects, experts agree on the importance of distinguishing sustainable plans from those that are not. Some signs that indicate that a project is reasonable include choosing a location close to the waste it manages and operating on a regional scale, with a plan to use the digestate as a local fertilizer and a design that guarantees total watertightness. On the contrary, there are signs that are authentic red flag: that the plant is far from the waste but close to gas pipelines, the absence of plans for digestate, the reception of waste in open pits, competition with other plants for raw materials or a logic of an industrial macroplant detached from the territory. In Xataka | A strange source of energy is putting Europe’s energy unity at risk: manure In Xataka | The ace up Spain’s sleeve to grow even more in the renewable energy landscape: biomethane Cover | Spencer DeMera and Eli DeFaria

China needs to manufacture cutting-edge chips to challenge the US for global supremacy. To achieve this it has two “Manhattan projects”

China is putting everything on the table. You have no choice. Either it develops its own cutting-edge semiconductor manufacturing technology or it will lose its fight for world supremacy with the US. Without 100% Chinese advanced chips its military capacity, the development of its models of artificial intelligence (AI) and the competitiveness of its technology companies will suffer in the medium term. Huawei and SMIC are making advanced integrated circuits, but they use machines from the Dutch company ASML and a technology known as multiple patterning that compromises its competitiveness. This scenario has caused the Chinese Government support with very juicy subsidies to companies that have the capacity to develop cutting-edge photolithography equipment, such as YesCarrierShanghai Yuliangsheng, Shanghai Micro Electronics Equipment (SMEE), Huawei or SMIC. However, its most compelling commitment has taken the form of two extraordinarily ambitious projects that seek to put the capacity to produce cutting-edge semiconductors in China’s hands before the end of the current decade. Shenzhen Hybrid SVU Machine Exactly one year ago, in March 2025, it was leaked that Huawei was testing the first extreme ultraviolet (EUV) photolithography equipment designed and manufactured entirely in China. Over the last twelve months information about this machine has been arriving very slowly, but currently we know enough to take this project very seriously. Its purpose is to place in the hands of Chinese integrated circuit manufacturers the possibility of producing highly integrated chips without using ASML equipment. However, unlike the EUV machines of this company from the Netherlands, the prototype of the project led by Huawei It uses an LDP (laser induced discharge) type ultraviolet light source, and not an LPP (laser generated plasma) class. On paper the LDP source is capable of generating UVE light with a wavelength of 13.5 nmso this Chinese prototype should be able to compete head-to-head with ASML’s UVE photolithography machines. The LDP radiation source is less powerful and simpler to implement than an LPP source, although it has been leaked that the Harbin Institute of Technology, which is located in northeastern China, is testing a 100 watt LPP source. The Changchun Institute of Optics, Mechanics and Physics appears to be able to manufacture the mirrors required for an EUV machine using atomic polishing techniques The most interesting thing about this project is that, if we stick to what we know, it seems to have shaped a hybrid photolithography machine which combines solutions developed by China by reverse engineering ASML’s deep ultraviolet photolithography (UVP) equipment in its possession and innovations devised by Chinese research centers. The Changchun Institute of Optics, Mechanics and Physics appears to be able to manufacture the mirrors required for an EUV machine using atomic polishing techniques with performance close to that of the mirrors produced by ZEISS for ASML. On the other hand, Tsinghua University has recently presented advances in polyteluoxane photoresists designed specifically for interact with the wavelength of 13.5 nm. Furthermore, Xuzhou B&C Chemical, which is one of the leading photoresist materials manufacturers in China, anticipates that in at most five years will have the capacity to produce large-scale advanced KrF photoresists (Krypton Fluoride) and ArF (Argon Fluoride). Be that as it may, the leaks maintain that the first test integrated circuits will be produced by this machine in 2028so that large-scale manufacturing will begin no later than 2030. Tsinghua University’s SSMB-UVE project continues to advance Each of ASML’s UVE machines incorporates its own ultraviolet light source, but Tsinghua University and the Chinese Academy of Sciences seek to generate this radiation, which is so important for produce advanced chips using a synchrotronwhich is nothing more than a circular particle accelerator that is used to analyze the properties of matter at the atomic level, such as various types of materials, or even proteins. It’s called HEPS (High Energy Photon Source o High Energy Photon Source). China’s plan is to place several semiconductor manufacturing plants around the particle accelerator to which the synchrotron will deliver the SVU light. SSMB-UVEwhich is the name of this project, comes from the English name Steady-State Micro-Bunching-UVEwhich we can translate as Microclustering in steady state for the generation of UVE radiation. A priori we may think that a particle accelerator has nothing to do with the manufacturing of integrated circuits, but we would be overlooking something very important: the HEPS synchrotron has the capacity to produce high power UVE light. In fact, it is a source designed to generate a large amount of radiation. China’s plan is to place several semiconductor manufacturing plants around the particle accelerator to which the synchrotron will deliver EUV light in the same way a power plant delivers electricity to its customers. The leaks ensure that this project has already completed the verification phases of the particle beams, although in principle nothing seems to indicate that this synchrotron will be able to be used to produce large-scale integrated circuits in the short term. Presumably the Shenzhen hybrid EUV machine will be ready before the SSMB-UVE project, but the path of the latter, if it finally comes to fruition, it will be much longer because it aspires to put a next-generation UVE radiation source in China’s hands. Image | Generated by Xataka with Gemini In Xataka | TSMC acknowledges that it has considered taking its factories out of Taiwan. It’s impossible for a good reason. In Xataka | The looming bottleneck in AI is neither RAM nor gas: it’s that TSMC’s N3 node is absolutely saturated

We thought that the great challenge of veganism was vitamin B12. A study suggests that social relationships are

Whatever there is taken the step to veganismfor whatever reasons, knows that the most difficult thing is not to give up cheese or meat, but to face Christmas dinner with the family or the Sunday barbecue with friends, since food is an event with a great social component. In this way, when someone decides to radically change consumption habits in a predominantly omnivorous worldnot only changes the plate, but also social relations. Now science has determined the tactics these people develop in order to survive social frictions. The data. The study, published in September 2025is not limited to conducting a survey among vegan people to analyze the impact on their social relationships. What they did was exhaustive field work between 2017 and 2022, combining in-depth interviews, observation and netnography, which is the analysis of the behavior of online communities. where debates arise about it. The goal here was none other than to understand exactly where and how everyday interactions are “broken.” And above all how they tried to compensate in an almost innate way. Social fractures. The researchers here identified that tensions in a social relationship do not arise from a simple difference of opinion about the most ethical diet, but from what they have called “relational fractures”, which are divided into three very clear areas: Co-execution: The simple act of cooking with another person, such as a partner, or sharing a meal becomes logistically complex. What was once a fluid ritual now requires planning, separate pans, and constant negotiation to arrive at a common dish. Co-learning: Family traditions, like inheriting grandma’s secret meatball recipe, are short-circuited. This means that the exchange of culinary knowledge between omnivores and vegans often comes to a standstill. Activities that may be everyday activities, such as going shopping or choosing a restaurant with other people, become logistical minefields where one has to balance one’s ethical needs with the preferences of others to choose, for example, a restaurant with a menu that suits everyone. Survival kit. So, if relationships fracture, how do vegans avoid becoming isolated? The researchers here discovered that, to maintain social peace and navigate these turbulent waters, vegans develop four specific “relational competencies” that sometimes appear without them realizing it, which we see below. Decoding. This is the ability to “analyze,” meaning vegans learn to anticipate how others will react to their diet and evaluate whether the environment is safe, hostile, or simply curious. Depending on the impression you have, your behavior will adapt to the environment by being more or less open with the topic. Disengagement. The second pillar is to deliberately separate food from social interaction, as it means that one will eat their vegan plate while another eats animal products, prioritizing company and conversation over dietary friction. Chameleon effect. The third adaptation consists of integrating so as not to attract attention in the group. This may mean, for example, bringing food from home to a social gathering or ordering a basic salad at a steakhouse without comment, all to prevent veganism from becoming the central topic of conversation of the evening. Abandonment. The last adaptation that has been detected in some vegans is where they directly give up different shared plans, such as stopping going to certain restaurants or social events. Even, in extreme cases, a distancing has been detected in an interpersonal relationship, since it becomes toxic due to the tensions that are generated. It is not born from nothing. One of the researchers has been exploring “morality in markets” for years and this led her to talk about indigenous and animal consumption practices. In this way, veganism is something that has been scrutinized for a long time in different studiessince it is not just about choosing what to eat, but it is an ethical stance that the omnivorous environment often perceives as a challenge to its own social and cultural customs. The big conclusion that can be drawn from all this is that the transition to a plant-based diet does not only require learning to read nutritional labels or discovering new recipes, but also requires a profound social and emotional re-education.. The long-term success of a vegan lifestyle depends as much on resilience at the supermarket as it does diplomacy at the dining table. Images | Anna Pelzer Xataka | Protein powder has become the star accessory of modern wellness. Nutritionists have something to say

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