confirms

The brutal collection of ‘The Hate’ confirms that the most profitable franchise of the moment is not Marvel or DC: it is Christopher Nolan

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‘The Odyssey’ has raised figures in its first weekend that are a true record for Christopher Nolan. The most significant thing, numbers aside, is that with this achievement he not only reaffirms himself as a prominent director in the league of great authors loved by the public and critics, in the style of Spielberg, but he competes directly in the field of sequels, blockbusters, Marvel and DC adaptations (where he has already made his name) and big-budget animation. Nolan already behaves (financially, at least) like a franchise. The numbers. The Nolan’s adaptation of ‘The Odyssey’ from Homer raised $124.5 million in its three opening days in the United States. On a global scale, the figure amounts to $264.1 million, the best worldwide opening of Nolan’s entire career, ahead of the $249 million achieved by ‘The Dark Knight Rises’ in 2012. Why it happens. Beyond the quality of the production and the expectation it has raised, it must be taken into account to explain the success that the premiere was strongly supported in premium rooms. IMAX screenings contributed close to $22 million to the international collection, 15% of the total, which was added to the $29.6 million domestically, 23.8% of the entire US box office. That is to say: large formats accounted for 53% of national revenue. Of course, critics praised the film, and aggregators like Rotten Tomatoes They give him a 95%, the highest grade of Nolan’s career, and sixth of yours to exceed 90% along with Memento, Insomnia, The Dark Knight, Dunkirk and Oppenheimer. Every three years like clockwork. Since the premiere of ‘Interstellar‘ in 2014, Nolan has taken up a tireless rhythm of one film every three years: ‘Dunkirk’ in 2017, ‘Tenet‘in 2020,’Oppenheimer‘ in 2023 and now ‘The Odyssey’ in 2026. Behind this regularity is an unusual production structure in Hollywood. His wife Emma Thomas has produced all of his feature films. They founded the production company Syncopy in 2001, with which Nolan develops his projects without depending on the usual machinery of a large studio. That autonomy partly explains why it can allow these wide parentheses: it does not need to prime a universe annually to justify million-dollar budgets. Fire test. That independence was put to the test in 2021. Nolan broke up with Warner Bros. after the studio decided to release its entire 2021 catalog simultaneously in theaters and on HBO Max. Nolan said the decision made no economic sense, in a statement in which came to comment that the company had gone from having “the perfect machine” for distributing films to dismantling it itself. He moved his next project, ‘Oppenheimer,’ to Universal, the same studio now backing ‘The Odyssey.’ No rival at the moment. Shawn Robbins, director of analytics at Fandango, summarized the phenomenon with a short phrase: “Death, taxes and Christopher Nolan”, referring, in a well-known Anglo-Saxon phrase, to three totems of life that are completely inevitable. Nolan has already gone in there. Of course, the director’s career seems to be an absolute concatenation of critical and public successes that attracts even non-regulars: of the 7.5 million tickets sold in the US, 43% of those spectators go to the cinema only a few times a year. ‘The Odyssey’ has no direct competition next week. The only threat on the calendar is ‘Spider-Man: Brand New Day’, which arrives in two weeks. On the other hand, ‘The Odyssey’ has not yet been released in China, Japan or South Korea, markets that could continue pushing up a figure that already corroborates that the days of Batman are long behind us and that Nolan does not need superheroes to sweep the box office. He alone is his own franchise. In Xataka | Christopher Nolan responds to Matt Damon’s defeatism about ‘The Odyssey’: “Cinema is vital and essential, and continues to transform”

science confirms the exact dosage of strength training

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For decades, when we thought about exercise for health, the image that came to mind was that of someone running or pedaling. Cardio exercise was the undisputed king of medical recommendations, but now a growing number of sports and medical professionals are raising their voices to give prominence to strength training as something practically mandatory if you want to reach an advanced age with a good quality of life. There is still evidence. It is not a gym exaggeration, but in recent years, scientific literature has taken a spectacular turn, demonstrating that lifting weights, using resistance bands or training with our own body weight is not just an aesthetic issue, but the true protective shield against aging and mortality. The tests. Until recently, we knew that being strong was good for preventing falls in old age, but current data goes much further. Muscle is a living endocrine organ that regulates our metabolism, and exercising it has a direct impact on the main causes of death worldwide. Without going any further, a review published in 2022 associated muscle-strengthening activities with a lower risk of all-cause mortality, but also with specific drops in the incidence of cardiovascular disease, diabetes, and various types of cancer. That same year, the American Journal of Preventive Medicine put precise numbers on the table by pointing out that any amount of strength training is associated with a 15% reduction in all-cause mortality, a 19% lower cardiovascular risk, and a 14% lower cancer risk. The most recent. If we go to this same year, a Harvard megastudy has finished closing the debate after following 147,000 adults for 30 years. Their findings are an instruction manual for longevity, discovering that performing between 90 and 119 minutes of strength training per week was associated with a 13% lower risk of all-cause mortality and a dramatic 27% reduction in mortality from neurological diseases. The quantity. One of the big myths of strength training is believing that to get medical benefits, you have to train like a bodybuilder or lift extreme loads every day. Science shows that the dose-response relationship is not linear, but rather that most of the benefits are concentrated in surprisingly moderate training volumes. Specifically, the optimal range is found in this study between 30 and 120 minutes a week. That is why going from zero to 45 minutes a week represents a brutal improvement in life expectancy. However, doing 5 hours of weight training per week does not multiply those benefits by five; In fact, the data suggests that a plateau occurs where the additional benefit is minor, and even exaggeratedly high volumes may not be optimal for overall longevity. The combination. If strength training is incredible on its own, when combined with aerobic exercise, the results skyrocket. Already in 2019, the European Journal of Preventive Cardiology reported that combining both types of training produced an additive effect, reducing general mortality by up to 40%. But the recent Harvard megastudy has raised that figure and points out that people who combine an aerobic routine with their optimal minutes of strength manage to reduce their risk of mortality between 45% and 58%. Images | Anastase Maragos In Xataka | Experts agree: “People who lift weights 2 hours a week and walk daily live longer”

A study confirms that they are more durable than previously believed

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For years, the fear of an electric car battery failing prematurely has been one of the great brakes to make the leap to this type of vehicles. And although they are still systems with a good margin for improvement, the technology has advanced a lot since the Nissan Leaf It was first put into circulation in 2010. In fact, several recent studies based on real data from hundreds of thousands of cars suggest that this fear was, to some extent, unjustified. Why it is important. The cost of replacing a battery is one of the main reasons why many buyers are still wary of electric vehicles. In fact, according to a 2025 survey by the firm AutoPacific shared According to the Wall Street Journal, the fear of having to pay for a battery replacement is the number one reason why potential buyers rule out an electric vehicle. In detail. The most recent datacompiled by the analysis firm Recurrent from thousands of real vehicles in circulation, show that an average electric vehicle retains around 95% of its original range after five years of use. And the trend improves the newer the car, since according to the study, 2026 models retain an average of 97% of their autonomy after three years and 95% after five. The difference with the first electric ones is even more striking if you look at the battery replacement rate. One in twelve electric cars manufactured between 2011 and 2016 had to change their battery at some point. Among those manufactured from 2022 onwards, that figure has fallen to 0.3%, according to the same Recurrent data. Between the lines. Why have things improved so much? Experts point to better battery chemistries, more sophisticated thermal management systems and increasingly precise control software. Viet Nguyen-Tien, a researcher at the London School of Economics specializing in electric vehicles, explains told the WSJ that these advances have allowed modern batteries to last as long as a combustion car engine, even traveling more kilometers. Additionally, a less obvious reason is that traditional lab tests were much more aggressive than real driving. Simona Onori, researcher at Stanford University, counted to NPR that in everyday use the car constantly accelerates, brakes and recovers energy, a pattern much less demanding on the battery than the extreme charge and discharge cycles that were previously used to simulate its wear. According to Onori, batteries “age very gracefully” when used like this. On the other hand, Cox Automotive, which manages used car auctions in the United States, has analyzed nearly 80,000 electric cars and found an average battery health of 92%. And among electric vehicles that are more than ten years old, more than 90% continue to circulate with their original battery, according to Recurrent data cited by NPR. Be careful, not everything is perfect. Batteries do degrade faster in certain circumstances. The fast direct current charging often accelerates wear. And it is that according to the telematics company Geotaba battery usually charged at high power loses autonomy at twice the rate of one charged more gently, although even then it retains about 90% of its capacity after several years. As shared in WSJ, always charging at 100% or leaving the battery at 0% for a long time also accelerates aging, as do extreme temperatures, whether cold or hot. And now what. It is still early to know how long these batteries will really last in the very long term, because the vast majority of electric vehicles in circulation have not even remotely reached the end of their useful life. Scott Case, CEO of Recurrent, think that people’s confidence in these batteries should be considerably greater than it exists today. Cover image | Eren Goldman In Xataka | Xavier Celda, Norauto specialist: “Many do not check the air conditioning gas because they do not spend 60 euros and the breakdown is 400”

Nintendo confirms when the new Switch 2 revision will arrive in Europe. And also that it will have less battery and more weight

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nintendo has confirmed that, starting this fall, a new revision of the Switch 2 will arrive in Europe. The idea is that, to comply with European regulations, the user can more easily replace the console’s battery. Although this change We already knew him for a few monthsNintendo has now offered more details about the release window of this new revision and how it affects the rest of the devices. Why is this happening now? The European Union approved in 2023 battery legislation that requires consumer products with integrated batteries to allow them to be easily removed and changed starting in February 2027. Nintendo, like any manufacturer selling hardware in the region, has to adapt before that date, and that is why it has already begun to make moves. In detail. According to has explained Nintendo itself through its official technical support, starting this summer several of its products in Europe will begin to be replaced “in a phased manner” by versions with replaceable batteries. The company assures that there will be “no difference in operation” between the current and revised models, although we will surely have to wait for this new revision to end up reaching stores to confirm that statement. The calendar you have shared is the following: Joy-Con controllers (some colors): since this summer, without changes in weight or battery capacity. Nintendo Switch 2 console: since autumn, weighing about 411 grams (10 grams more than the current model) and up to 548 grams with the Joy-Con 2 attached (14 grams more). Its battery goes from 5,220 mAh to 5,172 mAh, around 1% less capacity. Joy-Con 2 (separately): since this winter, with 2 grams more weight for each controller, without changes to the battery. Switch 2 Pro Controller: from this winter, with a 16% smaller battery (897 mAh compared to the current 1,070 mAh), although the controller will weigh 7 grams less. N64 and GameCube controllers for Switch 2: in early 2027, with slight changes in weight and, in the case of the GameCube controller, a slightly larger battery. Between the lines. Not all Nintendo products will go through this process. As they collect from VGC, the original Switch, the Switch Litethe OLED switchthe classic Switch Pro controller and other retro accessories such as NES, SNES or Mega Drive controllers. In addition, the user will not be able to choose which version they buy, so when the stock of the current model runs out, stores will begin to offer the revision with a replaceable battery. On the other hand, Nintendo has also announced that it will put battery replacement kits on sale for each product, although it has not yet given a date or price. Goodbye to the original Switch in Europe. As the company tells us, Nintendo has decided not to launch a new version of the original Switch in Europe. And instead of adapting it to the regulations, it will directly remove this console from sale in the region when appropriate. That doesn’t mean it’s now, but maybe in Europe we can already prepare for the end of Nintendo’s transition to Switch 2. And now what. Availability will not be the same in all European countries at the same time, according to recognize Nintendo. Furthermore, as could not be expected otherwise, Spain is among the markets where these reviews will arrive, as confirmed by the company. From here, what remains to be seen is whether these slight changes in weight and autonomy generate any real difference in the daily use of the console. In Xataka | In 1993, no one could find the supposed red ninja from ‘Mortal Kombat’. There was a reason: it didn’t exist yet

Science confirms that movement literally ignites your creativity

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Being in front of a screen or a piece of paper and needing ideas to emerge is something that for many people is an urgent need, but the problem here is that sometimes it is completely impossible. But the reality here is that we have a wonderful way of get these ideas to come to mind through a simple walk. Science has studied it. For decades, experts have been looking for a way to unblock our brain in this situation, and here a study published in 2014 had a lot to say, since the researchers demonstrated through four experiments that walking has a positive effect on the creative thinking that is often lacking. However, his greatest contribution was the dissection of what type of creativity benefits from movement. Specifically, they saw a drastic improvement in the divergent thinkingwhich is nothing more than the ability to generate multiple new and original ideas from a stimulus, but a null or even slightly detrimental effect on the convergent thinkingwhich is the ability to arrive at a single correct or logical answer. The best. With all this we come to the conclusion that walking is an extraordinarily powerful tool for brainstorming or starting a project from scratch, but it is not the best strategy if what we need is to solve a complex mathematical equation or find the exact answer to a test. In the real world. This study laid the foundation in a controlled environment where, in fact, part of the experiments showed that the effect persisted when walking on a treadmill in front of a blank wall, ruling out that the visual stimulus in the environment was the only one responsible. But when we leave here, the logical thing we think is that everything can end up changing. And to answer this, a study published in 2024 in American Psychologist took research out of the lab thanks to sensors and real-time evaluations in 157 young adults and analyzed daily steps in an everyday context. Your results confirmed that both acute walking episodes and the regular habit of going for a walk are directly associated with greater performance in verbal creative ideation. That is, the effect was not a laboratory anomaly, but rather translated perfectly to the real world. And it is confirmed again. This same year, a systematic review published in the journal PLOS ONE analyzed 23 independent studies where 1,036 participants were grouped together. Their conclusions indicated that there is a large and statistically significant effect between walking and having better divergent thinking. But there is still no evidence regarding convergent thinking. Images | Emma Simpson In Xataka | Psychology knows that feeling pleasure in the misfortune of others is not a psychopath: it is a very “human” reaction.

Someone used Opus 4.8 to analyze an MRI. What followed confirms that we cannot trust AI

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A developer named Antoine Finkelstein had had a sore right shoulder for weeks. After visiting an orthopedist, an MRI was performed on the affected area, and according to the medical report, he had a grade III partial tear in the subscapularis tendon. Finkelstein then did something else: he passed the resonance to Claude Opus 4.8 to see what the AI ​​told him about that image, and the result was striking because according to that AI model his shoulder was “intact.” AI gives you clues. The developer suspected that the clinic was perhaps trying to cash in on his condition, so he requested the raw DICOM data from the MRI. What they gave him was 266 MB which he crossed with currently available AI models. First, of course, he made a quick consultation with ChatGPT and in it he detected potentially important negligence: the clinic had applied shock wave therapy, which is not recommended for tendinopathies without calcification. He had also been injected with Traumeel, a homeopathic product registered in Germany “without therapeutic indication.” Let’s see what Claude Opus 4.8 says. To try to get to the bottom of the matter, the user decided to turn the Anthropic model into a doctor to ask for a second opinion. After setting up the model on the Claude Code platform, he allowed the system to install the code packages needed to process the raw medical images he had been sent. After an hour of processing these images, the AI ​​model issued a surprising diagnosis: the tendon that human doctors detected as 50% torn was completely intact. I don’t trust. The result was so contradictory to the human diagnosis that Finkelstein wanted to go a little further and set up a blind arbitration system. He instructed Claude to deploy several independent subagents, combining AI images isolated from each other to avoid confirmation bias. The verdict of all those subagents was unanimous: there was no partial or total break, and everything suggested that the human specialists had exaggerated the diagnosis. But quantity is not quality. This article gave rise to an interesting debate on Hacker News in which some important reflections were raised. It is important to remember, for example, that although AI eliminates the cost of consultations, having more information is not equivalent to solving the problem. As I said For one user, the situation reminded him of a problem he had with his car. He asked three different workshops for a solution, and each one told him something, and one even recommended a repair that he knew was useless. “The solution to uncertain information is not more information, which is certainly what AI can providebut better information, and right now AI can’t provide that.” AI is too nice. There’s another problem here: big language models are meant to be nice and “nice.” They are in a sense echo chambers that want to keep us happy, so they are not designed to contradict us in a harsh way, which makes it easier to confirmation bias. If a user enters his suspicions in the prompt when asking the chatbot, the AI ​​tends to agree with him: we often see how he begins by answering with “You are absolutely right…”. The problem with answers to medical topics is that they can be very different in independent sessions, but since the tone is always convincing and confident, they can lead to more confusion than the initial one. The expert thinks. A professional radiologist participated in that conversation and provided expert insight. According to your criteriacurrent AI models remain mediocre at interpreting medical images due to the lack of massive public training databases. These data are protected by medical privacy laws, and at the moment this problem has a difficult solution, but that user explained that the latest models are already close in accuracy to that of a first or second year resident doctor. The theoretical threat to the radiology profession from AI is something we we have literally been talking for years: for now It doesn’t seem like something like this is close to happening.. Who is responsible. There is another big problem with AI: there is no one responsible if something goes wrong after applying a recommendation. It is true that human doctors can make mistakes and may have biases or even commercial incentives (selling treatments). However, the legal difference is fundamental: the medical system has a series of licenses, regulations and responsibility management that penalizes negligence. AI forces you to manage yourself in the face of uncertainty. The problem is simple: trust AI or not. In issues as delicate as this, it is proven that AI is still far from being a real substitute for human experts. Today’s medicine may be “commoditized,” but AI, no matter how cheap or attractive it may seem, does not yet have the precision that would be needed for certain areas. As Finkelstein himself concluded, “I can’t know if I can trust the AI, so I’m in a kind of limbo in which I either try my luck with another doctor, or I wait and see if my shoulder improves with the rehabilitation I’m doing.” Image | Vitaly Gariev In Xataka | A team in Malaga has just developed a new medical AI. Your job: Help interpret MRIs, CT scans and medical images

The Government confirms that 90% of main roads already have fast charging nearby

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In recent years, we have seen how Spain has been updated in terms of the number of vehicle chargers. What a good part of them don’t work It’s a different story, but the truth is that infrastructure is taking on a different tone in the country. This same issue is what the Secretary of State for Energy, Joan Groizard, has recently focused on, during the opening of the Electric Vehicle Fair in Madrid (VEM) has taken stock of the state of the charging infrastructure. The data on which it has placed the most emphasis is that nine out of every ten kilometers of the main road network already have a charging point of at least 100 kW less than 60 kilometers away. Why does this data matter? The European Union approved the AFIR regulation (Alternative Fuel Infrastructure Regulation) to force member countries to ensure that their main transport corridors have high-power chargers at sufficient distances. The specific objective for 2030 is for there to be points of at least 150 kW every 60 kilometers on these roads. What has confirmed Groizard is that Spain is already close to that threshold in coverage, although there is still room to reach the power required by European regulations. Moves Corridors. The main tool to achieve these objectives is the program Moves Corridorspromoted by the Ministry for the Ecological Transition. On June 3, the IDAE published the definitive resolution proposal of its first call: 337 fast and ultra-fast charging projects, with powers of at least 150 kW, will receive just over 97 million euros in public aid, of the 200 million that the program had allocated. The remaining amount (more than 102 million euros) will be added to other items planned to finance a second call, expected in 2027, according to Administration sources. consulted by La Tribuna de Automoción. Shadow areas. The selection criterion for the projects in this first call has not been to install chargers where there was already infrastructure, but rather The so-called “shadow areas” have been prioritizedstretches where there were hardly any alternatives for those traveling by electric. And the problem with the charging network in Spain is not the points that there are in total, but in which places they were positioned. Accumulating chargers in large cities does not solve a long trip in the rest of the country. The market is also changing sides. Groizard also took advantage of his intervention at the fair to highlight the number of registrations last May. According to ANFAC data (Spanish Association of Automobile and Truck Manufacturers), diesel reached just 3.7% of sales, while pure electric cars reached 11%, a historical monthly record in Spain. Adding plug-in hybrids, electrification already exceeds 20% of the market. “The excuse of recharging has its days numbered,” warned Groizard. There are currently more than 55,000 public charging points in operation (more than gas stations in Spain). Of course, 69% of all of them It is made up of slow chargers with up to 22kW of power. The remaining 31% looks like this: 2,253 charging points between 22 and 50kW. 9,015 charging points between 50 and 150 kW. 3,206 charging points between 150 and 250 kW. 2,469 points of 250kW or more. Which still doesn’t quite add up. The progress in coverage is real, but the state of the network still has cracks. And it is that according to the organization’s data As of the first quarter of 2026, more than 17,000 charging points were still out of service, 24% of the total. The causes range from breakdowns to installed points that are not yet connected to the network. Communities such as the Balearic Islands (45.5% of inoperative points) or Galicia (39.5%) have the worst records. What’s coming now? According to share from La Tribuna de Automoción, in the coming weeks, the Ministry for the Ecological Transition will submit to public consultation the National Action Framework (MAN), a document that will take stock of the state of the charging infrastructure at the end of 2025 and will set the roadmap for 2026 and 2027, including the next call for Moves Corredores. It will also be the first official and updated photograph of where Spain really is in this deployment. Cover image | Andrew Roberts In Xataka | In February, historic rains broke the roads. Málaga has just received the go-ahead to repair the A-7 and A-45

Science confirms how many minutes of weight training per week reduce the risk of mortality

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For decades, when we thought about doing physical exercise, our minds almost automatically went to get older. cardiovascular activity. Running, swimming or cycling have been star recommendations to keep the heart healthy and extend life expectancy. Or at least live with a better quality of life. However, little by little we are normalizing the need to prioritize strength exercises at any age. How long. This is one of the big questions that anyone who needs to quantify the amount of exercise they do per day can ask themselves. There are clear recommendations, such as walk one hour a day at a brisk pacebut in strength we were quite orphaned. Now a new and monumental analysis has come to put exact figures on what until now were general recommendations, establishing a precise time window to maximize our years of life. What has been seen. The finding comes from a large observational study which has had 147,374 participants and exhaustive follow-up that has extended up to 30 years. Its good results have been published in the magazine British Journal of Sports Medicine. And when it comes to lifting weights or doing resistance exercises, intuition could dictate that “the more, the better”, but human physiology provides more limited metrics. The study data found that spending between 90 and 119 minutes weekly in resistance training routines was directly associated with lower overall mortality. In other words, spending between an hour and a half and two hours a week working our muscles is linked to a lower risk of dying from any cause. We have to be adjusted. What is truly revealing about this study lies in what happens when those 120 minutes are exceeded of weekly exercise. Anyone might think that the longer the time, the less likely you are to develop a major disease, but the reality is that above this time the benefits seem to stagnate. This shows that maximum efficiency is achieved in that limited period of time, demystifying the need to spend endless days in the weight room to obtain many more protective advantages at the metabolic level that allow us to extend our life a little more or make it of a higher quality. You have to combine it. Although strength training shines in this study, abandoning cardiovascular exercises would be a profound mistake. Here the research group itself pointed out that combining strength exercises with aerobic activity offered the best possible results, since this duality confirms that a hybrid approach dramatically maximizes long-term survival benefits. It’s backed up. In the past there were reviews that explored the relationship between training and mortality, this being one more that gives it much more strength so that it ultimately continues to be recommended for consultation to anyone, regardless of age. Because exercise here does not understand age, and strength exercise can be for the youngest, but also for the elderly who need to preserve their muscle to have a better quality of life in their last years of life. Images | Anastase Maragos In Xataka | In the fever to train strength, the gym has faced competition: more and more people train on the street

A macro study confirms that early menopause increases the risk of heart attack and stroke

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When we think of the menopausesocial and medical conversation is usually limited to obvious and short-term symptoms, such as hot flashes, mood swings, insomnia or the closure of the fertile period. However, this phase in the life of any woman has implications that go much further in terms of health as it involves a great metabolic and, above all, vascular change. A new vision. Now, the largest international study carried out to date has confirmed a reality by pointing out that when menopause comes early, the risk of suffering a myocardial infarction or stroke increases drastically, remaining stable independent of other traditional risk factors. The magnitude of the study. The research, to reach these conclusions with practically unwavering solidity, has resorted to the PURE-based macro-study, closely following a massive cohort of 111,619 women from 26 different countries, recording their clinical evolution for an average of 14.6 years. And the experts already point out that we are facing a methodological turning point in female cardiology. In figures. The findings evident in this study clearly segment the risk based on the age at which the end of menstruation occurs: When menopause occurs before the age of 40, it is called ‘premature menopause’ and carries between 27% and 30% greater risk of suffering major cardiovascular events such as heart attacks. In the case of a menopause between 40 and 45 years of age, it is called ‘early’ and registers a 14% higher risk of presenting cardiac complications. It is a risk factor. The most robust and worrying data provided by the research is that this increase in cardiovascular risk persists practically unchanged even after the researchers statistically adjusted the models to isolate some classic variables such as high blood pressure, diabetes, smoking or a sedentary lifestyle. This means that early loss of ovarian function is an independent risk factor in itself for these serious problems to occur. Because? The medical explanation behind this phenomenon lies in the abrupt loss of what cardiologists call the “estrogen shield.” It must be kept in mind that during the fertile age, estrogenic hormones exert a fundamental protective role in the circulatory system through various mechanisms, such as keeping cholesterol and triglyceride levels at bay. But estrogens also keep veins and arteries in good condition, promoting vascular relaxation and inhibiting the accumulation of body fat in arterial walls. Additionally, when estrogen levels fall prematurely, the process of forming lipid deposits in the arteries progresses at a much faster rate. The economic gap. One of the most innovative and alarming points of the PURE study is how the geographical context radically alters the impact of early menopause. And its conclusions show how the impact on cardiovascular health is almost double in low-resource countries compared to rich nations. For example, in countries such as Pakistan, Tanzania, Bangladesh, India and Zimbabwe, an overwhelming 43% of postmenopausal women had experienced early menopause. But in rich nations like Canada or Sweden the figure drops to 23%. A nuance. The authors introduce an important warning, since in countries with very precarious economies, chronic malnutrition usually causes what is known as hypothalamic amenorrhea, since the body prioritizes living over maintaining other functions such as reproductive functions. And although this confusion could partially inflate the statistical gap between rich and poor countries, the study clarifies that it does not in any way invalidate the main conclusion of the study: on a global level, without estrogen, the heart suffers. Images | Molly Wichman In Xataka | Nuria Marín, menopause expert: “Women continue to look for answers outside the health system”

That Anthropic has shut down OpenClaw is understandable. That they do so confirms that they are becoming the Nintendo of AI

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Peter Steinberger, the creator of AI agent OpenClawrose on Saturday to a ton of mentions on his Twitter account. In all of them they warned him of the same thing: Anthropic announced that Claude Code (Claude Pro/Max) accounts could not be used in OpenClaw. The decision left him anything but indifferent, and users of this agent have criticized a decision that, although reasonable, is, in a way, a disturbing tactic because of how and when it arrived. what has happened. OpenClaw is the AI ​​agent that, if you want, takes control of your machine and uses its apps to do for you everything you ask. Its operation is very powerful, especially if you use it with quality models such as Claude Opus 4.6 or Claude Sonnet 4.6. Many users were taking advantage of the Claude Pro and Claude Max plans to get the most out of OpenClaw, but Anthropic has said that that cannot be done. As explained, OpenClaw and other AI agents consume too many tokens and those plans are designed to be used in Claude Code for programming. If you want to use Claude with OpenClaw, pay. At Anthropic they do not prohibit the use of their AI models with OpenClaw, but they make it clear that if you want to use them you must use them with their API. It’s as if you bought the monthly transport pass for 20 euros to travel unlimited on the subway: it works perfectly when you go to and from work or university, but Anthropic says that you cannot use that pass to use it in your courier company that makes hundreds of trips a day. The token consumption in Claude Code is manageable, but in OpenClaw that consumption skyrockets and in Anthropic they want you to pay per use, not take advantage of the “flat rate” (with limits) of their Pro/Max plans. It’s understandable… Many users have attacked Anthropic and criticized that decision. Boris Cherny, one of the top managers of Claude Code, answered in X to a user who told him that decision “sucked”: “I know it sucks. At its core, engineering is about making hard decisions, and one of the things we do to serve a lot of customers is optimize how subscriptions work to reach as many people as possible with the best model. Third-party services are not optimized in this way, so it is very difficult for us to maintain it in the long term.” It is true that the massive use of Claude in OpenClaw raises the internal costs of Anthropic’s infrastructure: it does not pay off for them that so many instances of OpenClaw are being used with Claude, at least not if they are not used with the API. It is reasonable because these plans effectively “cheat” by being able to be used with this and other AI agents. But… …the moment is curious. This decision comes shortly after Anthropic has started to “copy” some of the OpenClaw features in their products, something we also expected. Claude Cowork, Dispatch and Remote Control have become the “official” ways to be able to do some of what OpenClaw does directly with Anthropic tools, and shortly after releasing them is when they begin to cover the way in which users can use their monthly plans. For Peter Steinberger, creator of OpenClaw, Anthropic’s decision comes now It is significant: “It’s funny how the timing coincides: first they copy the most popular features of our tool to their own closed product, and then they block access to open source.” Anthropic doesn’t lie. The technical argument that Cherny mentions is real, and the truth is that there is a capacity problem. Claude models are expensive to run, demand grows faster than infrastructure, and users of AI agents like OpenClaw consume resources much more intensively than conventional chat or Claude Code users. This is not sustainable, but it is also true that this decision comes three weeks after Steinberger “sold” OpenClaw to OpenAIAnthropic’s nemesis. Anthropic in Nintendo mode. This is the classic walled garden pattern: you see what works on another platform or rival product, absorb it, and then close the door. Nintendo has done this for decades with its platform developers, and Apple has perfected it with the App Store. The difference is that Nintendo and Apple had that walled garden from the beginning, and Anthropic is building it now. Although it’s not exactly the same. It should be noted that Nintendo is protecting an ecosystem with decades of irreplaceable IPs (Intellectual Properties): Mario, Zelda, or Metroid. It is normal that there is an access cost. Anthropic is doing that right now with Claude as the star product, but obviously it doesn’t have anything comparable (at the moment) to the IPs that Nintendo has. Here is another disturbing comparison: Apple or Nintendo charge to enter the ecosystem but it does not keep the meter running. Anthropic does: it has an increasingly closed garden, but it also forces the use of the API to use OpenClaw, with a pay-per-use model that is reasonable given Claude’s demand. But the rest do “leave”. What Anthropic has done clashes with what other AI companies are doing, especially when we talk about Chinese startups. The creators of Kimi, Minimax, GLM or the recent Xiaomi MiMo They do not have these policies: you can contract their monthly plans, very cheap, and take advantage of their models for OpenClaw without problems and without (barely) limits. It is true that these models are not as capable as Claude, but the way they act is still striking. In Xataka | OpenClaw changed the rules of the AI ​​race. Technology companies already have their answer: copy it

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