If anyone was waiting for the AI ​​bubble to burst, NVIDIA’s results have a message: sit tight

NVIDIA just published your results of the fourth quarter of its last fiscal year and has left Wall Street speechless. Revenues of $68.1 billion, a net profit that almost doubles that of the same period of the previous year, and a forecast for the following quarter that has far exceeded analysts’ expectations. And all this in a turbulent context where more efficient models and other alternatives are beginning to appear. The crash of DeepSeek is far away, and the demand for chips does not slow down. We tell you the numbers in detail. In case your position was not clear. Only a handful of companies in history have exceeded $100 billion in annual profit. Alphabet, Microsoft and Apple are in that club. NVIDIA has just joined them, with $120 billion in profits in the last twelve months, according to the report. The difference is speed: just three years ago, its annual profit was 4.4 billion. We can say with certainty that no technology company has ever grown so quickly on that scale. AI, and more AI. The engine that has driven these profits is its data center business, which generated $62.3 billion in the quarter, 71% more than a year ago. Within that segment, if we focus on their Blackwell chips, they have gone from entering 32.6 billion to 51.3 billion, while the networks (NVLink, Spectrum-X and InfiniBand) grow from 3,000 to 11,000 million. Gross margin is 75%, and earnings per share nearly double to $1.76 in GAAP terms (which is the official rulebook that companies follow to demonstrate transparent accounting). What Jensen Huang says. “Without computing, there is no way to generate tokens. Without tokens, there is no way to grow revenue.”, counted directly the CEO of NVIDIA in the meeting with investors. Their thesis is that in the new AI economy, computing power directly equates to revenue for their customers. That is why the large cloud service providers (Google, Amazon, Microsoft, Meta) continue increasing your capex budgetswhich together will exceed 500,000 million dollars in 2026 to build AI data centers. And NVIDIA is the main beneficiary of that expense. What DeepSeek has not broken, but accelerated. At the beginning of 2025, the emergence of the Chinese DeepSeek model generated an unprecedented tremor in the markets, leaving a simple question in our minds: if AI becomes more efficient, why do we need so many chips? The answer from NVIDIA’s results is that efficiency does not reduce infrastructure demand, it multiplies it. Every improvement in inference efficiency lowers the cost per token, encouraging more companies to deploy more AI applications, which in turn requires more compute. It’s like Jevons’ paradox, but applied to AI: efficiency expands the market instead of contracting it. Agentic AI as the next catalyst. On the same call with investors and analysts, Huang stood out that “enterprise adoption of agents is skyrocketing.” AI agentsthese systems that make decisions and execute tasks autonomously, require many more inference cycles than chatbots. They are the next step in the AI ​​value chain, and NVIDIA is once again in a privileged position. Colette Kress, CFO of the company, confirmed In addition, the first samples of Vera Rubin, the next generation of chips that will arrive later this year, have already been sent. China and the competition. Not everything is green. NVIDIA acknowledged that its forecast for the next quarter ($78 billion) does not include computing revenue in China. The company has generated just about $60 million from H20 chips since the Trump administration reapproved some sales in August 2025, according to SEC filings, and has yet to earn revenue from the most recently approved H200. Regulatory uncertainty with Beijing remains a small China in Huang’s shoe. In parallel, competitors such as AMD, Broadcom or Google’s own custom chips (TPUs) are gaining ground. But the NVIDIA CEO remains focused on his vision. And according to pointed at the meeting: “Every company depends on software, and all software will depend on AI.” As long as this is fulfilled, everything indicates that NVIDIA will continue selling the blades and picks. Cover image | NVIDIA In Xataka | NVIDIA was founded by three engineers, but only Jensen Huang remains CEO: “I wish I had kept some shares”

A company has filled a neighborhood with sidewalk outlets to charge electric cars. Their results are contradictory

In 2022, a German company called Rheinmetall proposed a new charging solution: put outlets on the sidewalks. Trying to find solutions for those who wanted to jump to an electric or plug-in hybrid car but did not have a garage, the company proposed a system to charge on the same street, without having to go to an electric station. Three years later: we have the results. A pilot test. After receiving approval from the authorities, the company began a pilot in 2024 in central Cologne and Lindenthala residential neighborhood of the city characterized by its low and individual houses. Neighborhood where, by the way, you will find the status of the local soccer team. The idea is simple, you park on the sidewalk and on the ground, on the curb, you find a plug hidden in a cover. You scan a code printed on it and connect the car with your own charging cable for AC use. As if it were any other charging point, both ends are joined and when the payment is completed, it is passed through the use of a mobile application. The results. In general terms, the results have been good. According to the company, a total of 2,800 charging cycles were carried out in the pilot test in one year. On average, the cars recharged 18 kWh, which in the city means more than 100 kilometers of autonomy for an electric car and between 80 and 100 kilometers on the highway (depending on its efficiency). They point out that each day the plug has been used an average of twice a day and that its availability has been 99%, so there have hardly been any breakdowns. The figure is good if we compare it with the European and Spanish average. In our country, public outlets They are only used 1.5 times a day and, on average, each charger is only busy between 30 and 120 minutes a day in Europe. Customer opinion. The company has conducted a survey of users who have offered their point of view to the system. It included the score given by the drivers (five points maximum) and some notes, complaints or recommendations made by customers. In total, the system has obtained 4.38 points out of five. But, above all, they have received very positive evaluations among customers over 60 years old, who value the simplicity of the system. In addition, they highlight that the plugs have not been damaged by water and that vandalism or uncivil acts (such as not picking up pet excrement) have not been found to have been a problem when recharging. A curious solution is that the cover that hides the plug has been designed to open with a small push of the charging cable, allowing the customer to lift said cover without having to touch it with their hand. Good idea, with some cracks. They point out in forumelectriccars that one of the main problems with this type of charging points is the cost of the plug. Each one of them, which has refrigeration and air conditioning to improve charging, costs 5,000 euros, so it is a bad idea compared to a traditional home charger. Furthermore, if you want to get the most out of the system, it would be necessary to reserve space for these charging points on the street, so there is no difference with any other public charging point unless the street is filled with plugs. That is, as happens with public outlets that are not located at a gas station, the parking space is reduced to reserve spaces that are not always occupied. Other proposals. Public charging is one of the great challenges that the electric car represents. One of its advantages is to leave the house with a charged car or, at least, take advantage of its parking lot to fill its batteries since alternating current is slow and most of the time a car is stopped. The most obvious proposal is the electric stations, with a huge number of high-power plugs available. another is fill shopping and leisure centers with chargerssince a visit to fully recharge the battery can take days or weeks (depending on daily trips) without plugging in our car. With an average of 50 kilometers per day, a car that drives 500 kilometers of autonomy in the city has 10 days to go without plugging the car back in, just three days a month. But if we want to bring public charging to the city streets, Portugal, United Kingdom either Netherlands have been experimenting with public outlets on streetlights. The system is as simple as including sockets on the curbs but with the difference that the socket comes from a street lamp and does not require installation on the ground. The paradox of slow recharging. The problem with this type of recharge is that slow charging takes hours and hours with the car plugged in. If a socket charges our car at 7.4 kW of power, it will be necessary to spend about 10 hours to completely fill the battery of a 60 kWh vehicle, a small size that is on the border between those who want the car for an urban environment and those who want to dare to travel with him. Those refills They are interesting if the price is low But they require that, to get the most out of it, we have to leave the car parked there for an entire working day or an entire night. The system, therefore, is certainly inefficient in terms of servicing more than one car. To charge at this power, the data says that most electric car drivers charge at home. Outside of it, the customer usually chooses to recharge at higher powers. For example, a 50 kW plug can now fully charge a car in less than three hours, which is the time we spend watching a movie at the cinema. And on a trip, the most practical thing is usually to look for … Read more

Productivity had become an obsession. Until leisure has started to give better results at work

The constant pressure to perform to the maximum has marked work life for a long time, leaving rest almost forgotten. A recent study shows how reserving well-planned leisure time changes the perception of daily routines and contributes to improved performance at work. Experts have verified that organize free time actively through crafts or other forms of abstraction brings improvements to creativity and motivation in your work tasks. This finding questions the belief that only by working non-stop can we achieve good work results. Let the brain create things. A group of researchers from the University of East Anglia in the United Kingdom and Erasmus University Rotterdam in the Netherlands investigated on the effects of creative craft-based entertainment during employees’ leisure time. The result of the experiment was not an improvement in the morale and motivation of the employees who participated in the study, but rather it contributed to these employees offering a more creative response in solving the problems that arose at work. Improvements in daily work life. The workers who participated in the study felt that, by exercising new manual skills, they better appreciated the processes of their crafts, making them gain value. The curious thing is that the change was bigger in the workplace than in his personal life, even though it was his leisure time. “We were surprised to see that crafts had a greater impact at work than in personal life. We expected similar benefits in both areas,” explains Professor George Michaelides, from UEA Norwich Business School. Curiously, the group that noticed this improvement the most was the one formed by the most senior employeesthose over 61 years of age. The explanation for this phenomenon is found in cognitive aptitude, a brain condition that is activated during learning processes. Gymnastics for the brain. Just as they collect the studies of Professors Gilkey and Kilts, of the schools of medicine and business at Emory University, carry out various creative activities that require a motor and cognitive combinationlike playing the guitar, juggling or learning a new language, helps expand the neural system and makes it more communicative. That is, the development of new skills through crafts was improving the “physical fitness” of the employees’ cognitive system, and the results were more visible in those more prone to cognitive decline and memory deterioration due to age. Keep “fit“Cognitive aptitude improves performance in decision making and problem solving, as well as in the generation of new ideas. The capacity for abstraction. One of the keys to the use of crafts or pleasurable leisure activities is that they act as a natural stress reducer and depressive symptoms. “Hobbies are already known to be good for well-being. But our study shows that hobbies not only make you happier, they can also help you feel more fulfilled and creative at work. This goes beyond simply relaxing or having fun (like watching Netflix non-stop) and turns hobbies into something that helps people grow,” says Dr. Paraskevas Petrou, the lead author of the study. Beyond the cognitive improvement derived from the development of the neural system, a study from Cardiff University found that the use of crafts or repetitive activities, how to knitinduces the brain into a state of full attention that increases abstract thinking activity by up to 25%, which contributes to the generation of new ideas and improves problem solving. In Xataka | Feeling overwhelmed at work is normal, but it is not ideal: six techniques to avoid it and be much more productive Image | Unsplash (Elena Mozhvilo)

Researchers removed Instagram and TikTok from 300 young people to see if their anxiety decreased. The results speak for themselves

The debate about whether social networks are the new tobacco for the mental health of the generation Z It’s been on for years. There are many young people who They can’t go without watching TikTok completing the streak with their friends, uploading stories of what they eat to Instagram or simply away from the cell phone. And this is something that can be tremendously harmful. What we knew. Until now we could make one of them, and parents undoubtedly remember this message when they spend many hours in front of the phone. Even companies offer the tools to be able to limit the amount of time that we spend in an app and it even applies limits to us. With numbers. But now science has shed light on this problem with a published study in JAMA Network Open that provides concrete data. The premise was simple: ask a group of young adults (ages 18 to 24) to reduce their consumption of social networks this week. Once done, we wanted to see if the symptoms of anxiety, depression or insomnia were reduced. And it is precisely the excessive use of social networks is related to depressionsince it generates social isolation, low self-esteem, cyberbullying or even physical disorders due to the effects of blue light from the screen. So… Does giving up the cell phone also improve the quality of life of young people? The study. To do so, they not only focused on what users said they did with their mobile phones, since lying can be very easy in this case. What they did was passively record what was done with the phone through the ‘digital phenotyping‘. In total, there were 373 participants in this study, of which only 295 were able to complete the intervention, which was completely voluntary. They only had to reduce consumption for one week of the main social networks: Facebook, Instagram, Snapchat, TikTok and X. The results. Simply put, the results showed significant clinical improvement across key areas after just seven days. The data indicated that depression symptoms were reduced by 24.8%, anxiety by 16.1% and sleep problems fell by 14.5%. Interestingly, the study found that the effects were much more pronounced in those participants who already had symptoms of moderate or severe depression at the start of the experiment. Don’t let go of your cell phone. A priori, one might think that when a young person automatically leaves social networks aside, their cell phone will be of absolutely no use to them. But nothing could be further from the truth. He digital phenotyping revealed that although social media use fell from about 2 hours a day to just 30 minutes, total screen time increased slightly by 4.5% and participants spent 6.3% more time at home. In this way, users replaced the infinite scrolling of TikTok with other digital activities such as messaging, browsing the internet or even playing games. However, despite still being glued to the screen, mental health improved. This reinforces a theory that is gaining weight among experts: the problem is not the screen itself, but how we use it. The study points out that objective use time has a weak association with mental health, since what is really harmful is “problematic use”, such as negative social comparison or emotional addiction to platforms. Easier apps to leave. We can all have more ‘affection’ for a specific social network, which is surely more difficult to stop using. In this case, it was seen that it was easier for users to reduce the time they spent on TikTok or X. But Instagram or Snapchat were the “hard bones” to beat. Specifically, 67.8% of Instagram users and 48.8% of Snapchat users failed to comply with the reduction and continued to use them significantly during the detox process. It is not a treatment. Although the percentages sound like a victory, it is necessary to maintain the usual scientific skepticism. Dr. John Torous, co-author of the study, warns in statements collected for him New York Times that reducing networks “would certainly not be your first or only form of treatment (for mental health problems),” although it is worth experimenting with. This focuses on the fact that the study has some limitations such as the lack of a reference control group and it was not seen how long the detoxification process from social networks lasted. But what did not improve was loneliness, since eliminating these social networks in people can have the opposite effect by also cutting the connection link that unites them with other people. Images | Panos Sakalakis Vitaly Gariev In Xataka | Social networks were once a place to tell our lives. Now the trend is different: “zero posts”

Science wants to put ‘microrobots’ into our bodies to medicate us. They have already given good results

One of the great problems of modern medicine in the treatment of different human ailments is the “killing flies with cannon” approach. This means that when we have a headache and we take paracetamol, this medicine is distributed throughout the body and not only where it needs to take effect. But this is something that may end up changing thanks to microrobots. The importance. That the medication ‘walks’ throughout the body seems completely irrelevant as long as it has its analgesic effect, but the reality is that it is the responsible for many side effects that are generated. For example, taking a simple ibuprofen to relieve pain or reduce inflammation seems like a wonderful thing. But the fact that it has a general effect on the body also causes the blocking of mucus production in the stomach, which can lead to one of its most ‘famous’ side effects, such as the generation of stomach ulcers when abused. And when we talk about the much more serious side effects, it can cause many clinical trials of new drugs to have to be stopped because of this. But simply with a system that makes the medication act in a specific place in the body, this problem could be alleviated (in part). A new advance. A team of researchers from ETH Zurich has published in the magazine Science a solution that brings us a little closer to the setting of the movie Amazing Journey: a platform of magnetic microrobots ready for clinical use that are capable of traveling through blood vessels and releasing their cargo into the affected tissue. Bradley J. Nelson, co-author of the study and professor of robotics at ETH Zurich, says this is just the beginning: “We’re just the tip of the iceberg. I think surgeons are going to look at this and I’m sure they’ll have a lot of ideas about how to use it.” A simple grain of sand. In this case we are not talking about a metal robot with gears, but rather a capsule of approximately 1.69 mm in diameter that is designed to dissolve inside the body. We can rest assured that we will not have thousands of grains of metal sand in our bloodstream. But to get here, the engineering behind it is not at all simple. One of the challenges, logically, is that its application would be viable within the human body. To do this, the team had to balance three key factors such as: biocompatibility, drug loading capacity and magnetic control. The result was a spherical gelatin matrix that has three components: Iron oxide nanoparticles to respond to magnetic fields. Tantalum: a dense metal that can be ‘seen’ through radiology techniques in order to follow its path through the body. The medication you want to apply. How it moves. In addition to the capsule, what is important is how it moves until it reaches the target where it must act. For this, an electromagnetic navigation system called Navion is used. To do this, coils are placed around the patient’s head to generate a magnetic field around it that allows the capsule to move. In this way, a surgeon, for example, will be able to control the capsule almost as if it were a remote-controlled car to be able to reach the desired action point. To do this, there are different ways of moving through the vessels: by rolling, by dragging or by navigating the blood flow itself. A suicide mission. Once this microrobot reaches its destination, the doctor will be able to activate the final phase. Using high-frequency alternating magnetic fields, the iron nanoparticles inside will heat up, which will cause the gelatin matrix to melt in a matter of 40 seconds, releasing the drug at once. In their tests, they managed to transport rtPA (a powerful drug to dissolve thrombi) to a clot in a vascular model, managing to restore blood flow in less than 20 minutes. When will it reach the hospitals? Although the system is quite promising, it will take time to reach patients. The researcher himself points out that clinical trials could begin within three to five years. In addition to thrombi, applications are being considered to treat aneurysms, arteriovenous malformations and very aggressive types of brain cancer. It’s not the first time. The medicine every time tends more towards personalization of treatments. In cancer we already see it with use of therapies such as CAR-T which focuses on training the immune system to specifically attack a person’s tumor cells and not healthy cells. A completely targeted therapy like the one proposed in this system, but in this case it is applied in the daily clinic (although it has a very high cost). The same happens with the immunotherapy with the use of antibodies. In this case, science looks for those particles that are unique to tumor cells and that are not present in healthy cells. In this way, drug weapons can be created that directly attack cancer cells. In Xataka | The rarest element on Earth aims to cure cancer. And Europe is already accelerating its production

The most unexpected treatment against cancer is LED light, and it is giving good results

Currently there are many research groups that have a very clear objective: find a cancer treatment that is effective, specific and above all safe. Something that can be really complex because of everything that cancer hides behind it, but science continues to give us good news. The last one comes from the University of Texas and the University of Porto which have developed a technique based on tin oxide nanoflakes (SnOx) and LEDs that allows cancer cells to be destroyed with precision. The current problem. The therapy par excellence today in the fight against cancer, without a doubt It’s chemotherapy and radiotherapy. The first of these has numerous problems that have been tried to be corrected, such as low specificity, that is, it attacks both cancer cells like the healthy ones. And this ultimately produces many side effects that can cause you to not continue with the treatment. This makes the goal of science to seek specificity and for the treatment to attack only cancer cells. This is something that is being tried to achieve with immunotherapy and techniques like CAR-T which ultimately is part of personalized medicine for each patient and which offers a very specific selection of the type of cell to destroy. But science has not stopped here. The discovery. One of the techniques that appears to be promising is photothermal therapy (PTT). The concept in this case is quite simple to understand: inject nanomaterials into a tumor and then heat them using light. This logically causes a localized increase in temperature, which selectively destroys the cancer cells that have been marked before. The problem until now was materials and light. Many photothermal therapies require high-powered lasers, which are expensive and can damage surrounding tissue. Now, a team of researchers from the University of Texas at Austin and the University of Porto have found the key to changing the rules of the game. A secret ingredient. The team has developed a new photothermal agent called nanoflakes that are made of tin oxide. After all, they are tiny sheets with a thickness of less than 20 nanometers and what is really ingenious is how they were manufactured. The really ingenious thing is how they made them. They started from a cheap and abundant material such as tin disulfide, which ironically is useless for photothermal therapy. In this way, through a ‘green’ and scalable process called electrochemical exfoliation with oxidation, which only uses aqueous media, they managed to transform the inactive tin disulfide into tin oxide that was already ready to fight cancer. And the light came. Once this material was available, all that was left was to expose it to the LED irradiation low-cost that emit infrared light at 810 nm. In this case we are talking about radiation that is very safe and does not damage healthy skin as can occur with radiotherapy, and it is also extremely cheap and accessible to everyone (even developing countries). Results. To test the effectiveness, researchers have tested cells in culture. The first thing they saw was that this treatment had no effect on healthy cells, that is, it did not destroy them. But the best comes when applying it to cancer cells results in a great reduction in the different colonies. Specifically, in skin cancer there was a 92% reduction in the viability of tumor cells, while in colorectal cancer this percentage dropped to 50%, but still maintained good results. And all thanks to an increase in temperature from 37 °C to 50 °C in 30 minutes that killed cancer cells. The future. This study not only presents a more efficient material, but validates its use with safer and more economical light sources. The researchers themselves point to the potential of LED systems for applications such as skin cancer treatment, which could theoretically be self-administered at home. This would be a great advantage for patients and would reduce the burden on health systems, although there is still a lot of research ahead to see if this therapy can be viable in a range that will surely not be less than 10 years. Images | National Cancer Institute Logan Voss In Xataka | Colon cancers are increasing alarmingly among young people. We have a suspect: sedentary lifestyle

“Guided missiles” are revolutionizing cancer treatment. And they are already giving results

Chemotherapy marked a great revolution in the treatment of different cancers despite its many problems in the nonspecificity of the ‘attack’ that caused healthy cells to also be affected by its effects. Although attempts have been made to increasingly specific chemotherapiesthe reality is that the next natural step in the evolution of the treatment It is immunotherapy, which is a field that continues to advance, giving us more and more joy in the fight against cancer. But there is a revolution that wants to go much further, and it is nothing more than taking all the good things that immunotherapy has with the high potency of chemotherapy. And this ‘cocktail’ has a name: immunoconjugates (ADC). The current problem. Traditional chemotherapies have been seen as a really aggressive treatment that generates a large number of side effects by attacking absolutely everything they encounter. This forces us to rethink the strategy. For this, it has been thought in immunotherapy Basically what it does is ‘wake up’ our natural defenses so that it can attack the tumor with its own tools. Something that It is personalized for each individual. by extracting, for example, their T lymphocytes to ‘reprogram’ them and make them fight against the tumor, which is nothing more than their own cells. But the next step requires this specificity with greater potency than the stimulated immune system can provide. And this forces us to look for new therapies that have a similar mechanism, although it goes further in the way of applying the drug to the target cells. And this is where we are in the fight against cancer. The goal of treatment. Precisely the future focuses on personalized treatments for each of the patients who have cancer in their body, without having to generalize with a drug for one type of tumor. This is achieved with treatments that are considered ‘remote-controlled missiles’ or ‘Trojan horses’ that promise greater specificity when attacking a tumor cell and leaving the body’s healthy cells ‘calm’. But always taking into account the particular characteristics of a person’s tumor. This is what is achieved with ADCs which are designed like a missile with lethal precision. Its mission is to deliver an explosive charge of chemotherapy into the tumor cell, largely ignoring healthy cells, and the results are promising in the early phases of research, demonstrating its great potential to cure more patients in the early stages. That’s how they work. The technology behind ADCs (Antibody-Drug Conjugates) is as elegant as it is powerful. It is made up of three key parts: The antibody that acts as the guidance system. A monoclonal antibody designed in a laboratory to search and fit like a key in a lock to specific proteins, a kind of “antennae” (receptors), which are found massively on the surface of tumor cells. And the point is that each tumor cell has different ‘antennas’ and that is why it is important to find the most suitable antibody. The payload, which we can assume is our ‘warhead’ which is a very powerful chemotherapy molecule and so toxic that it often cannot be administered in normal chemotherapy mode due to the large effects it has. So, here we are combining chemotherapy with immunotherapy. The linker. A mechanism that binds the antibody and the cargo so that it can travel ‘comfortably’ through the blood until it reaches its target tissue. The process is pure military strategy: the ADC travels through the body, the antibody detects its target (the cancer cell), anchors to it and the cell, deceived, absorbs it. Once inside, the linker breaks and releases the chemotherapy, annihilating the malignant cell from within and without affecting the ‘neighbors’. A before and after. At the congress of the European Society of Medical Oncology (ESMO 2025) without a doubt this treatment has been on the lips of many experts. And it is logical seeing the good results that have been reported in this regard. You just have to see a recent study published in the prestigious magazine New England Journal of Medicine that confirms that this ADC such as trastuzumab deruxtecan is more effective than conventional chemotherapy in cases of metastatic HER2+ breast cancer, showing improvements from 7 to almost 10 months without tumor progression. Another treatment, sacituzumab govitecan, also has shown important results before him triple negative breast cancerwhich is one of the most aggressive and could have the worst prognosis. The result is also very promising: an improvement in survival and quality of life. The hidden side. Like all cutting-edge technology, ADCs are not without challenges. They are not harmless. One of the geniuses behind these studies, the Spanish Javier Cortés pointed out to the side effects that could occur, mainly diarrhea and lowered defense. This made him have to point out that “in general, Trojan horses give a toxicity that, in relation to traditional chemotherapy, is usually somewhat better.” But there is also another front ahead: in some patients with this treatment the tumor continues to grow. The investigation now focuses on understanding it: The tumor cell receptors may mutate and are not the appropriate target, the chemo release mechanism within the cell may fail, or the tumor may simply be resistant to that particular chemo. The future. What is being targeted right now is the possibility of mixing ADCs with immunotherapy or even combining several ADCs with each other. But where things get more interesting is the possibility of loading these ‘Trojan horses’ with radioligands, that is, rradioactive dioisotopes to apply radiotherapy very selective on cancer cells. In this way, a wide range of possibilities open up for the treatment of cancer. Images | Angiola Harry National Cancer Institute In Xataka | Colon cancers are increasing alarmingly among young people. We have a suspect: sedentary lifestyle

Microsoft has put co -pilot in Excel. And you have also notified that you do not use it if you need the results to be correct

Artificial intelligence has finally landed In one of the most famous spreadsheets in the world: Excel. But he hasn’t done it as many imagined. Talk to the program in natural language and automatically solve everything for us? Only in part. Copilot’s shortcuts allow to summarize, classify and order databut they do not turn Excel into a agent able to take control of a project from beginning to end. In addition, the novelty comes with clear limits: the function can make mistakes. Microsoft is testing co -pilot as a native function within the Excel calculation engine. The idea is simple: write an instruction in natural language within the sheet and obtain a result that is placed directly in the grid, with the same behavior as any Excel exit. Integration allows you to continue working with defined ranges, tables and names without changing the structure of the file, and the results are updated when the data changes, without resorting to scripts or external accessories. Copilot is landing in Microsoft Excel As we see, it is a useful function, but with clear limitations. At the moment we cannot ask in natural language things such as “fuses the books of the subsidiaries, make everything to euros to the official change, eliminate duplicates and enter me a quarterly consolidated balance with comparative graphics.” Copilot, for now, plays in another land: Understand instructions in natural languageYes, but it does it within Excel and always about the data you have on the sheet itself. Accepted that Copilot is not an automatic pilot, it is worth exploring what it is practical. Microsoft points to four daily fronts that are resolved without abandoning the sheet: Rain of ideas without leaving the sheet. Ask for a list of concepts, titles or keywords from a brief description. If we need it, we can ask that you rewrite a text in a lighter or more formal tone and leave the result ready to polish. Summaries that go to the point. Point out a wide range and request a short text with trends, peaks and falls. This is useful when a table must be converted into an understandable paragraph for a report. Direct classification in the grid. Deliver a column with comments, tickets or survey responses. We can ask that you return labels such as “positive/neutral/negative” and a brief category. Everything would turn to new columns to continue working. Lists and tables on the fly. From a description, which proposes a table with the columns that we indicate (task, responsible, date, state). It is a basis for organizing without wasting time mocking. ⠀In the official noteCatherine Pidgeon (Excel team) offers a very clear example of what Copilot can do today. Imagine a sheet with a column full of opinions about a new coffee maker in the office. Some value flavor, others complain about noise or deposit size. Copilot can read that column and return, right next to us, a table with two fields: the feeling of each comment (positive, neutral or negative) and a category Cut that helps you group (“taste”, “noise”, “capacity”). In minutes we would go from a messy list to something analyzable. There we decided: filter for the most frequent problems, count a category or prepare a summary. And how is it used in practice? Exactly like any other Excel function: writing the sign equal to the beginning of a cell and then the name of the function. In this case, Simply put = co -pilot () and add inside the instruction in natural language or the range of data that we want to use as a context. There are no tricks or hidden menus, it is invoked as invoked a = sum () or un = search (), which makes learning minimal and experience is familiar from the first moment. It is time to put the caution on the table. Copilot works within the book itself: it does not access the web or documents of the company, and its results must be reviewed and validated before including them in reports or business decisions. Microsoft is clear about it: it is not appropriate for high -risk scenarios (with legal, regulatory or compliance implications). There are also operational limits: the function has quotas of use (up to 100 calls every ten minutes and 300 per hour). Microsoft is clear about it: it is not appropriate for high -risk scenarios. What we are seeing should not surprise us either. Artificial intelligence has advanced by giant steps, but still has a weak point: it can be wrong. These inaccuracies are usually called “hallucinations”And, although technology improves with each generation, the companies that develop it warn that It is not convenient to re -one hundred percent. It is almost a courtesy reminder that we have already normalized: every time we open a chatbot as COPILOT, Chatgpt either GeminiWe find a warning that reminds us that what we read can contain errors. Will the day come when these failures disappear? There is no clear answer. Even paying for the most advanced versions, the fastest or most expensive, absolute security does not exist. That is the reflection that also applies in Excel: Copilot is useful and opens possibilities, but never replaces the tranquility it gives for oneself that the numbers walk. Copilot does not reach everyone yet. Microsoft is gradually display They are on the beta channel, both in Windows and Mac. The company ensures that in the coming months it will also be available in the Excel Web version through the Frontier program. Nothing must be done to activate it: the function appears on the sheet when the requirements are met, and its use is completely optional. Images | Microsoft | WIRESTOCK In Xataka | If the question is whether there is an AI bubble, Sam Altman has just answered. One with which he is winning

In 1950 two scientists wondered if possible a nuclear bomb of 10 gigatons. Its results are hidden locked up

On October 30, 1961, a Soviet bomber furrowed the skies of the Arctic towards Novaya Zemlya. Under his fuselage he hung an artifact the size of a bus: an unprecedented nuclear pump. At 11:32, the called TSAR pump He released. A parachute slowed its fall, allowing the plane to move away. Then, a detonation illuminated the sky with a fireball of almost 10 kilometers in diameter and a fungus -shaped cloud that amounted to more than 65 kilometers. The show was surreal: the pump, With 50 megatones explosive (more than 3,300 times that of Hiroshima), became a symbol of the Nuclear madness. But it could be much worse. The awakening of a new era. With the atomic bombardment of Hiroshima and Nagasaki In August 1945, the world changed irreversibly. Those bombs, 16 and 21 kilotons respectively, they marked the beginning of the destructive power without a paragon of Nuclear weapons. However, despite their fearsome capacity, these weapons were only the first step towards a much more sinister technological escalation. What would later transcend the most reckless imagination. The most powerful pump ever detonated would be That Soviet tsar of 50 megatones, although designed to reach 100. However, the most disturbing thing is that this was not the summit. In hidden, the United States had still planned More huge. The “Super” concept. Hiroshima and Nagasaki bombs were based In fission: A chain reaction in which heavy nuclei are divided releasing energy. But as we said, in parallel to their development, some scientists imagined a second stage: The fusion. This implied union of light nuclei (as deuterium and tritium) to form a heavier one, releasing even more energy. It happens that this reaction required an initial fission explosion to activate, which would give rise to the concept of the Hydrogen pumps. In the 1940s they were just a theoretical speculation … but everything changed very soon. Photograph of a replica of the tarum pump housing Communism comes. After the detonation of the First atomic bomb Soviet in 1949, the United States accelerated its thermonuclear programs. The fear of communism, enhanced by the revolution in China that same year, made the National Security Council recommend quadruply military spending. In that context, the figures of Edward Teller and Stanislaw Ulam appear, who devised The design that even today supports the H bombs. In 1952, the “Mike” test of Operation IVY demonstrated for the first time the Thermonuclear principle: an explosion of 10.4 megatones (500 times Nagasaki) that left a crater of 1,900 meters wide. Despite such force, that was not enough for Teller. The Soundy germ. Two years later, in 1954, the so -called “Shrimp” bomb during the Castle Bravo test. A powerful explosion was expected, but the result of 15 megatons (1,000 times Hiroshima) even surprised its designers, both by strength and by the devastating level of radiation released. However, Teller’s impetus did not stop there either. I wanted more, Much more. It was then that one of the most delusional and terrifying projects of nuclear history emerged: the Sundial Project. Designed by Teller and his colleagues from the Livermore Radiation Laboratory, the plan proposed a new destruction scale: no already kilotons or megatones, we entered In the gigatons. A couple of brothers. They were designed Two weapons: Gnomon and Sindial. Gnomon would act as “primary”, with a detonation of 1,000 megatons aimed at detonating Soundy, which would reach a power of 10,000 megatons, that is, 10 gigatons. For placing it in perspective, he thinks again The image of the beginning. Well, the figure exceeds 200 times the tsar bomb, and almost does not fit in the conceptual framework of the physics of conventional explosions. The potential apocalypse. The logic behind Sindial overflows any traditional calculation. To such powers, the laws of escalation of destruction They lose any validity: The heat, pressure and energy released would be so monstrous that, a priori, they would open a hole in the atmosphere. In fact, A report Del Bulletin of the Atomic Scientists pointed out that a pump like a sundial, detonated about 45 kilometers of altitude, could cause fires in an area of the size of France. The death toll would be unthinkable, not only because of the immediate explosion but by global radioactive sequels. Hiroshima, with 140,000 victims, would be a sigh against cataclysm that would represent Sindial. It was not science fiction. Although it might seem like a laboratory fantasy, the Sundial Project It was not a joke or an eccentric occurrence. Declassified documents and historical analysis indicate that Livermore’s team worked seriously For years in the development of Gnomon, with concrete plans to test it in the Redwing operation of 1956. That test was canceled, but the mere existence of the plan shows to what extent the fear, scientific ambition and deterrence had pushed the superpowers to border the abyss of the unacceptable. Echoes of Sindial. Suindial never materialized, but his mere conception forced A critical reflection In American politics. The growing destructive power of these weapons overflowed not only military strategy, but also ethics, logistics and land physics itself. While many ruled out their tactical utility for being impracticable (a pump of such dimensions was impossible to launch), its potential as an instrument of symbolic terror was enormous. As with The TSAR pumpits value was more political than operational: a floating threat that showed how far a nation could go if I wanted. Monster in the shadows. Finally, the Soundal project is It was diluting between political restrictions, international treaties and practical sense (without serving as precedent). The Ratification of the treaty Partial prohibition of nuclear trials in 1963 was a brake on atmospheric tests, which in practice made it impossible to continue advancing in the development of extreme performance weapons. The strategy then went on to favor smaller, portable and operational multiple eyelets, leaving behind the vision of total apocalypse that represented Sindial and its cousin Soviet sister. Imagine the unimaginable. What’s doubt, today sundial is just a footer … Read more

Some scientists have reviewed 99 studies on intermittent fasting. Its results are not very optimistic

The popularity of intermittent fasting has grown over the last years, partly by a series of scientific studies that endorsed their potential when helping us lose weight. However, sometimes the results of individual studies do not agree with the global image of the matter. Not so effective. A new study has in doubt The ability of intermittent fasting as a superior way of losing weight. The analysis concluded that, although some forms of intermittent fasting could offer a slight advantage, the results obtained with these were not significantly better than those obtained with the simple caloric restriction. The intermittent fasting. The concept intermittent fasting It refers to a series of diets based on a temporary caloric restriction. We cannot speak of a single flash form since this temporary restriction can occur in several ways. Conventional forms of intermittent fasting imply not consuming any food during a specific time window, more or less broad, in certain days, which can be alternate or successive and in different proportions. It can also refer to drastically restricting the calories we consume in certain days of the week. Sometimes a non -intermittent hourly restriction is also included in these diets, that is, a more conventional fast. Review and meta -analysis. Evaluating the effect of these diets is not easy, but over the last decades, various teams of researchers have launched to it, obtaining very diverse results and sometimes even contradictory. Solving this type of discrepancies is what is sought with the tool we call meta -analysis. Metaanalysis start from a systematic review of literature in which the team compiles all studies in the field in a specific time interval. Metaanalysis consists in the statistical evaluation of the results obtained in compiled quantitative studies to obtain an average effect through a broader sample which allows strength to the conclusions. In other words, solve discrepancies. 6,582 participants. In this case the meta -analysis included 99 studies individuals that added in total 6,582 participants. As explained by the team responsible for the new study, among these participants, the average body mass index was 31 and about 90% had some health disease or condition. The results showed that fasting on alternate days (restricting our food consumption to alternate days) was the only option that showed an observable benefit in weight reduction. However, this reduction (1.29 kg on average) did not exceed the 2 kg threshold defined by the study responsible for the study. The details of the study were published In an article In the magazine BMJ. 99 studies, and we still need more. Metaanalysis usually serve to settle scientific knowledge in one subject, but at least in this case it is still more to investigate, admits the responsible team. The heterogeneity of dietary strategies, the small size of the samples and the limited evidence are limiting factors indicated by the team. “The evidence today provides some indication that diets based on intermittent fasting have continuous energy restriction benefits for weight loss and cardiomethabolic factors. Explain the team. In Xataka | What if we are doing the bad intermittent fasting? Some experts propose to focus only on carbohydrates Image | Xataka with Gemini / I Yunmai

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