closer

We had a very serious problem with our resistance to antibiotics. Now we are closer to solving it

by

One of the great threats that humanity faces today is without a doubt the antibiotic resistancewhich leads to emergence of bacteria that are resistant to all pharmacological weapons that we have. This forces science to have to look for new antibiotics and new ways to ‘attack’ a bacteria. And at the moment it seems that we are approaching this great milestone with a new antibiotic that was hidden in plain sight. The problem. Having bacteria that you cannot compete against is undoubtedly a death sentence for the person who is unlucky enough to be its host. Something that responds to the mechanisms that these microorganisms have to evolve and develop ‘tactics’ that allow them to escape our antibiotics. A very typical situation in a hospital, especially where a bacteria that has been exposed to a treatment, but has survived, will adapt to that environment. This makes the WHO categorize antimicrobial resistance as “one of the top 10 threats to global public health.” Put another way: we are running out of antibiotics that work, since bacteria are evolving faster than we are discovering new drugs. And this is something that is also magnified by our own fault by taking antibiotics uncontrollably or not complete treatment guidelines appropriately. That is why the discovery just made by a team from the University of Warwick and Monash University is so spectacular: have found a “silver bullet” that had been hidden in plain sight for 50 years. The discovery. Published in it Journal of the American Chemical Societywe are talking about an antibiotic that, in early tests, has been shown to be up to 100 times more powerful than existing drugs against high-priority resistant bacteria, such as feared Staphylococcus aureus methicillin resistant (MRSA). The molecule in question is called pre-methylenemycin C lactone (compound 5), and it has arrived to try to save humanity from this pandemic we are experiencing. But the most surprising thing is where they found it: in the Streptomyces coelicolora soil bacteria that is literally the “model organism” for the production of antibiotics and which has been studied endlessly since the 1950s. That is to say, we had a possible solution before our eyes and we had not realized it until now. This bacteria produces a well-known antibiotic called methylenemycin A that is low potency and is not used clinically. However, scientists decided to investigate not only the final product, but the intermediate steps of its biological “assembly line.” This is where it was seen that it intermediately produced methylenemycin C, which has much more powerful antimicrobial effects. And this is a lesson for science: we are always left with the result of the reactions (that is, the final product). But now what should be done is analyze everything that happens between the first substrate and the final product. Because we are seeing how methylenemycin A was discovered 50 years ago and it was not until now that one of its intermediate products has been a protagonist in this fight. As. To achieve this, the team used genetic engineering. Basically, they “sabotaged” the bacteria’s production chain by creating a mutation that eliminated the gene. mmyE. When this piece is missingthe bacteria could no longer complete the process and began to accumulate the “intermediate steps.” Something similar to when in a production line we remove one of the tapes and an intermediate version of what we were manufacturing begins to accumulate. The tests. When they tested the activity of the new molecule, the results were astonishing. Compound 5 (pre-methylenemycin C lactone) was “one to two orders of magnitude more active” (i.e., 10- to 100-fold) than methylenemycins A and C (the final products). In this way, it was finally possible to see that the result was up to 256 times more powerful than even some drugs. Something that is revolutionary. The great hope. Being powerful is all well and good, but the real battle is against resistance. That is, when the bacteria come into contact with this antibiotic, they can develop a system to get rid of its lethal effect. And this is where there is good news, since after subjecting the bacteria E. faecium At increasing concentrations of the new antibiotic for 28 consecutive days, a standard method for forcing the emergence of resistance, no resistance was detected. A new way to search. Until now, the intermediate products generated in the production of different medicines had been ignored. Now this study puts an end to this custom, since it has become clear that the identification and testing of the intermediate elements of biosynthesis can lead to a great revolution. Now with this new treatment, preclinical tests with animals remain to assess its safety with the aim of subsequently moving on to tests in humans and the evaluation of its side effects. Images | CDC Myriam Zilles In Xataka | AI has opened a chest that had been closed for almost 4 billion years: the salvation of antibiotics

29 years ago we clone to the Dolly sheep. Thanks to this, today we are one step closer to solving the fertility crisis

by

Imagine a future in which the infertility caused by the lack of ovules or sperm is no longer an insurmountable obstacle. A future where two men can have a biological child together, or where A woman who has lost her ability to produce ovules For age or for a cancer treatment may have offspring with its own genetics. This future, which until now belonged to science fiction, is a little closer thanks to a revolutionary advance that has been published in Nature. Biology This advance, which seems like a science fiction, has been made by the team of researchers at Oregon Health & Science University, led by Dr. Shoukhrat Mitalipov. In this case they have managed to develop an experimental technique that forces a skin cell (somatic) to reduce your number of chromosomes in half. It is, in essence, the most crucial and complicated step in the creation of a gamete (an ovule or a sperm). A process they have called mitomeiosis. To be able to understand it, you have to know that all the cells of our body have in total 46 chromosomes in its nucleus. But there is an exception: sperm and gametes that They have 23 chromosomes. A very important number so that when an ovule and sperm merge, they have a total of 46 chromosomes. That is why it is revolutionary that they have managed to get a skin cell to have 23 chromosomes to be an ideal candidate to give offspring. The trick. The natural process to create these haploid cells (with 23 chromosomes) is called meiosis. A very complex type of cell division that has been investigating for a long time. This made it replicate in a laboratory, which is known as in vitro gametogenesis (IVG) was one of the greatest challenges of biology. Something that now reminds us of what we already saw with the Dolly sheep in the cloning process. OHSU’s team addressed the problem in an ingenious way. Using a technique similar to cloning, called nuclear somatic cell transfer (SCNT). A technique that is complex, but can be summarized in three different steps: The first thing is to take a donated human ovule and extract the genetic material. In this way, the ovule maintained all its cytoplasm with the organelles, which ultimately is like the machinery that the cell has to produce energy and carry out many processes such as meiosis. Once done, a skin cell is taken (a diploid cell with 46 chromosomes in a 2N state) and is extracted the nucleus inside. Now it only remains to introduce the core of the skin cell into the ovule that has been emptied. The result. In this case it was amazing, since the ovule cytoplasm could ‘deceive’ the skin’s core, forcing it prematurely into a state similar to the metaphase of the Meiosis. This caused its 46 chromosomes to be organized in a spindle ready to divide, despite having skipped the DNA duplication phase in the cell cycle that is before the division of the genetic material. The problem. However, here they met a wall. In nature, the entrance of the ‘active’ sperm to complete its division, being mediated by a large number of zinc. But in this case, when they tried to fertilize the SCNT ovules with sperm, the vast majority (almost 77%) remained ‘arrested’ without reacting. The natural signal was not enough for this artificial construction. The solution in this case went to develop an artificial ‘starter’ key. After sperm fertilization, they applied an assisted activation protocol an electrical pulse by electroporation to simulate the calcium entry caused by sperm to its entrance, followed by a treatment with a chemical inhibitor called Roscovitin. And it is something that ended up working. Forced activation made the modified ovules leave their arrest and complete the division. The 46 chromosomes of the cell were separated, leaving an average of 23 chromosomes within the fertilized ovum (now a zigoto) and expelling a small polar body from the rest, having achieved the long -awaited ploidy reduction that was the objective of this experiment. Progress. The embryos resulting from this experiment containing chromosomes of the skin and sperm cell, beginning to divide and even some reached the blastocyst phase (an early development of about 5-6 days), with a success rate of 8.8%. This shows that genomes can integrate and work together. It’s just a test. The authors who are still a long way forward, since for now it is a “proof of concept” by not being a perfect replica of natural meiosis. In this case, segregation is random unlike meiosis, where it is ensured that each daughter cell receives a copy of each of the 23 types of original chromosomes. In this project the separation of homologous chromosomes (the paternal and maternal) was completely random. This generates aneuploid embryos that are incompatible with life. In addition, it also lacks ‘cross -rise’ or crossovera vital mechanism in meiosis where paternal and maternal chromosomes exchange fragments creating genetic diversity. This is something that is not present in this process and that takes away a lot of variability. The future. Despite the limitations of this study, work is a fundamental milestone. It aligns with other laboratories such as the Japanese Katsuhiko Hayashi that in 2023 managed to create functional ovules From male mice skin cells, with which healthy offspring were born. In the long term, the implications of these studies give hope to those women who suffer from infertility due to lack of functional gametes and who want to have offspring with their own genetics. The same happens in same -sex couples that also open the door for a couple of men (using a skin cell to create an ovule) or women (creating sperm) can have biologically related son between both members of the couple. Although we cannot also forget that right now there is a fertility crisis that causes that in Spain, for example, there is reduced birth rate. This is also conditioned that it is … Read more

that Russia is getting closer

by

1,300 kilometers from the north pole is the town more northern inhabited of the world. We refer to the Norwegian people of Svalbard, an extreme region, a gigantic ice cream, much above the Arctic Circle where 2,500 people officially have Forbidden to die. And yet, what worries them most has nothing to do with their climate or geographical place. What worries them most is that Russia is getting closer. Forbidden to die. It We have counted. In Svalbard one of the most peculiar rules on the planet governs: it is Forbidden to die In Longyearbyen, its capital, because the permafrost prevents the decomposition of the corpses and preserves viruses and bacteria for decades, which was already checked when bodies buried in 1918 still contained traces of the Spanish flu virus. Since 1950the cemeteries stopped accepting deceased and any seriously ill or elderly person must move to the continent to spend their last days there, while the few still visible burials are vestiges of previous times. The rule reflects both the hardness of living in the Arctic Like fragility of a settlement where life, and even death, is conditioned by ice eternal. The new Arctic border. I told the weekend Bloomberg. On the top of the island of Spitsbergen, in the Svalbard archipelago, Raise Svalsatthe largest earthly satellite station in the world, with 170 domes that connect every few seconds with satellites in polar orbit and provide critical data for weather, navigation, climate research and maritime security. Its location, 78 degrees north and with access to airports and ice -free ports, it gives this Norwegian enclave a unique strategic relevance in an Arctic every time More disputed. Norway sees it as a Sovereignty symbol And it has expanded with energy and communications projects, collaborating with agencies such as NASA, ESA or Oneweb. However, the dependence of this technological node and its potential dual use reinforce the Russia tensionwhich accuses Oslo of rape Svalbard’s treaty When there are submarine cables and demonstrate too much emphasis on territorial control. Svalbard Satellite Station Russia and symbolic persistence. Just a few kilometers from Longyearbyenthe Norwegian capital of the archipelago, resists BARENTSBURGa Russian mining settlement that, with just 400 inhabitants, on Soviet flags and maintains a bust of Lenin as a reminder of its history. Managed by the state company Trust Arktikugolthe people have renewed facilities, open a gym, promoted tourism and signed agreements with Russian universities, although their mine lacks real economic viability. In practice, it represents A strategic symbol For Moscow in the Arctic. After the invasion of Ukraine, the relations between the Norwegian and Russian communities cool: They canceled visits Tourist to Barentsburg, joint sports activities were suspended and many Ukrainian miners returned home. What previously survived the Cold War today has broken under the pressure of war and sanctions. BARENTSBURG Svalbard and uncertainty. The Norwegian government insists in that “Svalbard is as Norwegian as Oslo”, reinforcing his control through visits from authorities, indirect military presence and international projection. However, everyday reality is that of a community of 2,500 people of more than 50 nationalities, Tourism dependent And of expensive imports in a hostile environment where permafrost melts, basic services are limited and the last Norwegian coal mine is about to close. The transition from an industrial past to a post -mimine economy leaves open questions: What will replace mining, how much tourism can be allowed and how to sustain a diverse population without causing internal tensions. The Life in Svalbardmarked by polar bears, mortal avalanches and the lack of maternity or geriatric centers, remember that there everyone lives in time borrowed. “ A global rivalry. The War in UkraineTrump’s gestures claiming Greenland and the Russian militarization of the Kola Peninsula have turned the north into an epicenter of Geopolitical rivalry. With the accelerated thaw opening routes such as the passage of the northeast and multiplying the strategic value of resources and communications, Svalbard emerges as a microcosm of the worldwide struggle: A place where science, defense and trade are intertwined with political symbols and sovereignty shocks. For Longyearbyen residents, the transition has been palpable: from a mining people cohesive to a community exposed to global currents that generate diffuse identity and tensions with their Russian neighbors. As expressed A veteran resident, even in the coldest times of the cold war, local cooperation persisted. Now, that coexistence also seems lost, leaving Svalbard in the awkward first line of a new era of Arctic Competition. Between tourism, science and climate. Plus: the mines It raises an economic vacuum that only partly They fill tourismincreasingly massive with the arrival of cruises, and scientific projects such as World Seed Bankwhich barely offer employment. Meanwhile, Arctic heating, four times faster That the global average melts permafrost and compromises infrastructure, makes energy more expensive and multiplies natural risks. The dilemma of how much tourism growth accept, how to attract permanent families and what role in global research defines the next Svalbard stage. And in the midst of these tensions, the inhabitants try to maintain their identity and resilience, aware that they live in a territory where nature and Geopolitics They weigh as much as the will of their own residents. Image | Sprok, Bernt Rostad In Xataka | Eight Rompehielos have turned Russia into the power of the Arctic. Your secret: Nuclear force to operate all year In Xataka | We already know why Greenland is so important: the key is called Giuk and gives access to China and Russia east of the US

The iPhone 17, closer than ever. Apple already has a date for your keynote and this is what we expect

by

The countdown has already begun. If you are thinking of changing your iPhone or you simply want to follow closely the latest news of the Cupertino company, there is a date that deserves to be on your calendar. Apple has just sent the invitations for your next Keynote. It will be the September 9 at 10:00 in the morning In Pacific Hora (19:00 Spanish peninsular time) and, as every year, it can be followed live through streaming. What to wait at the Apple event on September 9 Everything indicates that we will see the traditional renewal of the iPhone family. The great unknown is what the protagonist of this year will be. According to rumors and leaksthe focus would be put on the expected iPhone 17 Air. We are talking about a device that, as its name suggests, would aim to become One of the lightest and most thin market. It would arrive with a premium topped as usual in aluminum and glass. As we said, the device would not arrive alone, but accompanied by the rest of the company’s proposals. Among them is the presentation of the new iPhone 17, iPhone 17 Pro and iPhone 17 Max. Maybe the absence of the Plus model attracts attention. Everything points to what The iPhone 17 Air will take its placealthough with a different strategy that could serve to further boost sales. The autumn event could also bring news in the range of accessories of the US company, with special attention to new Apple Watch and a possible renewal of the AirPods. On the other hand, everything indicates that the day of the event will announce the Final versions of iOS 26iPados 26, Macos 26, Tvos 26 and Watchos 26. We are talking about Versions that are currently available in Beta. In development. Images | Apple In Xataka | Google Pixel 10: having a telephoto sensor without having to go to the pro models is happiness

Intel is closer than ever to be chopped. A giant is interested in buying its chips factories

by

The possibility of intelid for a long time. Two years before get out of this companyPat Gelsinger, the former Director General of Intel, He acknowledged that he saw with good eyes The possibility that the network of integrated circuit factories is somewhat broken down from the company’s matrix. At that time, More than three years agothis was already an interesting option to increase the competitiveness of its chips production plants, and in current circumstances it seems even more advantageous. At the beginning of last April Reuters and The Information assured that the Board of Directors of Intel and TSMC had reached a principle of agreement that was pursuing to constitute a joint company that would be responsible for the management of Intel semiconductor factories. Its plan was that TSMC would have a 20% participation in the new company, so presumably Intel would maintain a majority participation. Finally, this initiative did not come to fruition, but the possibility of splitting the Intel chips factories of the company’s matrix is still on the table. And now it is the Japanese investment group SoftBank who, According to Financial Timesis interested in controlling the Intel Integrated Circuit Production Infrastructure. SoftBank has something very important: the support of the US government As we explain yesterday, SoftBank has injected into Intel 2,000 million dollars, which has consolidated it as the sixth main shareholder of this company. According to Reutersthis Japanese company has promised not to participate in the Board of Directors, and it will not buy integrated circuits produced by this American chip manufacturer. However, SoftBank’s plan does not end here. And is that, According to Financial TimesMasayoshi Son, the general director of this investment group, is interested in Intel chips factories. SoftBank has promised not to participate in the Board of Directors of Intel In fact, again according to this means of communication of British origin but currently in the hands of the Japanese company Nikkei Inc., before formalizing the injection of 2,000 million dollars in Intel, SoftBank communicated to the board of directors of this company its interest in its interest in Buy the full semiconductor production subsidiary. A priori it is reasonable to anticipate that the US government would not see with good eyes that a foreign company is done with the total control of Intel chips factories, but SoftBank is not any company. The most important initiative of how many has launched the Trump administration to protect US leadership in the field of artificial intelligence (AI) is The Stargate project. And this plan is led by an American company, Openai, and another Japanese: SoftBank. The company directed by Sam Altman is responsible, in broad strokes, for the development of technology and infrastructure management. And Masayoshi’s company are responsible for financial administration. Stargate will cost no less than 500,000 million dollarsand it is evident that the US government Trust SoftBank. During the next few weeks we will check if the purchase of Intel Prosper Chips factories, but all likelihood the administration will not be an obstacle. Image | Intel More information | Financial Times In Xataka | The next revolution of the chips is approaching. Intel, Samsung, TSMC and AMD already work on glass substrates

Quantum computers will change the world when they don’t make mistakes. This milestone is closer thanks to quantum gravity

by

Some experts believe that all the effort that is being carried out in the field of Quantum computing Not anywhere. One of the members of the scientific community more critical of quantum computers is the Israeli mathematician Gil KalaiProfessor at Yale University. According to this researcher, the increase in the number of states of quantum systems and their complexity will cause them to end up behaving like classical computers, so the superiority of the former will end up evaporating. However, the absence of unanimous support by the scientific community should not tarnish the notable effort and advances that many research groups are doing, some of them in Spanish institutions such as the CSIC and others integrated into the structure of companies that have very bulky resources, such as IBM, Google or Intel, among others. In fact, as expected, the latter defend that the long -awaited error correction will reach quantum computers and will allow them to face a much broader fan of problems than that of current prototypes. Terra Quantum bets on quantum severity to correct errors The main problem facing quantum computers in the field of error correction is noise, understood as the disturbances that can alter the internal state of the cubits and introduce calculation errors. The strategy for which many of the research groups that are involved in the development of quantum computers are opting for monitoring the operations carried out by the cubits to identify real -time errors and correct them. The problem is that from a practical point of view this strategy is very challenging. QMM technology reduces errors by up to 35% in current quantum processors Logical cubits represent a way to overcome the difficulty of the use of hardware or physical cubits, which are extremely noise sensitive, and, therefore, prone to make mistakes. Each logical cubit is constructed abstractly on several physical or hardware cubits, so that a single logical cubit encodes a single cubit of quantum information, but with redundancy. It is precisely this redundancy that allows to detect and correct the errors that are present in the physical cubits. The error correction strategy proposed by the researchers of the Swiss Terra Quantum company is not an alternative to the solutions in which we have just inquired; It is a complement. In fact, as explained in the article they have published in Advanced Quantum Technologiesits QMM technology (Quantum Memory Matrix) Reduce errors by up to 35% in current quantum processors. And, in addition, it reaches 94% fidelity using ten times less cubits than conventional methods. An important note: Terra Quantum’s scientific article has been reviewed by pairs. Terra Quantum has tested its QMM technology in IBM superconductor processors, and works. It only requires adding a quantum circuit that does not alter the architecture of the processor, although it is very ingenious. In fact, its operation is inspired by A principle of quantum gravity which maintains that the space-time continuum can be described as a network of me memory cells. It is a complicated idea, it is true, but the really important thing is that we know that this theoretical concept is the one that has inspired Terra Quantum scientists the design of their quantum circuit of errors suppression. Anyway, this innovation joins the effort that IBM, the MIT and other organizations are making to invite us to tie the future of quantum computers with a very reasonable optimism. Image | IBM More information | Advanced Quantum Technologies In Xataka | Bitcoin encryption and other cryptocurrencies will fall. And those responsible will be quantum computers

Lyft, closer to landing in Europe. The platform has taken a key step to buy Freeow from BMW and Mercedes

by

Lyft wants to enter Europe and has begun to move. The company has notified the National Commission of Markets and the Competition the purchase of Freeow, the taxi app that until now shared BMW and Mercedes-Benz. The operation, valued at 175 million euros It represents a key movement: if completed, it will allow Lyft to deploy in more than 150 European cities, including Madrid, Berlin and London. Instead of building a network in Europe, it is committed to acquiring a platform that already operates in some of the most important markets on the continent. Freeow not only has a consolidated presence in key cities: it also has local agreements, active fleets and an approach that fits the European ecosystem, more regulated than the American. The operation would allow Lyft to enter with a base already made. The operation is not closed. On July 9, Lyft officially notified the purchase from the National Commission of Markets and Competition (CNMC). With that step the initial phase of the regulatory process in Spain is activated: the agency now has a month to pronounce. If you consider that the operation needs a more detailed analysis, a second phase will be opened that could be lengthened between three and four months, As Europa Press collects. Only after overcoming this process the transaction could be completed. For users, nothing changes for now. But there are clear promises. Both Lyft and Freeow have confirmed that, for the moment, there will be no changes in the experience of use. The app will continue to function as until now. However, in the medium term, improvements such as more consistent prices, faster vehicles and new functions are expected. They are future objectives, even without a concrete date, but that are already in the road map of both companies. The Integration of Freeow would allow him to significantly expand his scope, both in number of cities and in potential volume of users. According to its internal estimates, the total market to which it aspires would reach more than 300,000 million annual journeys, with an expected increase in gross reserves of 1,000 million euros. Freeow does not disappear: he maintains his team, his brand and his local DNA. The agreement contemplates that Freeow retains its current structure. There will be no mergers or rebranding: the brand will remain active and directed by the same team. That continuity is part of the strategic value of the operation, since it allows Lyft to access a consolidated network without altering its internal operation. An agreement that meets two different, but complementary cultures. Lyft arrives with an experience focused on digital platforms and large volume management. Freeow brings the knowledge of the land: relations with fleets, authorities and operators in each city. Both companies assure that it is not an absorption, but a collaboration that aspires to climb what already works, without losing local identity. Images | Lyft/Freeow In Xataka | Europe has denied 1,100 million euros to Spain with a single goal: that we pay more for diesel

Now they have decided to kill her and bring her closer to Netflix

by

The face washing that Mediaset has given to its streaming platform, until now known as mitele, and what is called Mediaset Infinityit has been spectacular. A considerable reformulation in the visual, technical streaming With their same weapons. The new Mediaset Infinity. Announced at the end of May, this change equals the Mediaset Spain website with that of the Italian matrix of the group. Among the web sections are both live and letter emissions, with exclusive content derived from linear programs and even in the style of what Atresmedia does, original productions for this digital environment. Access to all contents becomes completely free, something that was limited in Mitele. There will also be a premium part, heiress of Mitele Plus in which there will be no advertising interruptions and there will be the possibility of starting a direct from its beginning and downloading content. A family air. It is inevitable to think of a clear inspiration for this redesign: Netflix and the rest of the platforms of streaming that have gone in their shadow (at least the netflix prior to last and much discussed redesign, openly thought to imitate the style of social networks as Tiktok). In Mediaset Infinity we have categories that follow each other horizontally and extend vertically, with visual and very recognizable icons, and organization for seasons and chapters within each program. The influence is even evident in the highlights of the Homeand it is not a bad idea: any spectator has already become accustomed to the use of these menus and organization almost intuitively. Technical improvement. The guts of this new Mitele incarnation have also improved, with an optimized search system, a better organized user area and, above all, an important leap in terms of speed and accessibility. A year and a half of joint work between Mediaset Spain and Mediaset Italy that has set in a remarkable jump for the platform: now the content search is much faster and, above all, moving through the platform is as effective as in any other streaming platform, without the need for unnecessary waiting for seeking programs or hidden chapters. The reorganization of the page works perfectly. Blur and new account. Since its creation in 2011, Mitele has experienced abundant problems, especially technical type: access difficulties that demanded to resalrate the application, Poor performance even with good connections, limited compatibility with Many devices (especially with certain Smart TV models), reproduction errors and availability … a series of problems that were the reflection of an app that had been outdated and that had not been able to evolve at the same rate as the connections and user devices. All the same. It is not an exclusive problem, yes, by Mitele: traditional television have always had problems adapting to Smart TV and consumption on demand. The motives have been varied, from technical and hardware limitations (by compatibility of new televisions with apps) to changes in the business model (to traditional chains, accustomed to a linear model, they have a hard time facing a model that requires flexibility, investment in technology and new forms of monetization, apart from negotiating new emission rights and adapting content), passing through a fierce competition of the streaming platforms, which they They have an advantage because they are native. Inherit users. What Infinity is going to be found are Mitele users: 3.7 million unique users in January, A growth of 16% With respect to the previous year, in addition to almost 2 million viewers on average a day on the platform. Undoubtedly, this growth has played in favor of encouraging Mediaset to make the leap towards the transformation into the new platform, no matter how and a half of development a relevant investment may have needed. A push for Telecinco. Thanks to the huge impulse that the latest edition of ‘The Island of Temptations’ is giving to all platform programsto ‘late’ seems to work Better without his alma mater since, on the other hand, the 1 does not seem to settle completely or in its disastrous afternoons nor in the Competition with ‘El Hormiguero‘, Tele5 has found a break. Vespertine bets such as ‘Jorge’s newspaper’ are consolidating themselves as some of the most value for Telecinco, which he needed from the output of ‘Save Me’ from his grill programs that provided him with solidity. This new platform is another step in a proposal of greater modernity for the group, as well as more ease of access to its programs. Something that undoubtedly their spectators will appreciate, knowing how the contents of both spaces are contaminated. Header | Mediaset In Xataka | The last edition of ‘The island of temptations’ has not only been a viral phenomenon: it has saved the month of Telecinco

PlayStation has just come closer to the arcade game with its new hardware: this is Project Defiant

by

Today is day of State of playbut the Japanese company has not reserved the event only for the games that will encourage the second half of the year. There has also been room for hardware, specifically to present what they have baptized as Project Defiant. A command with arcade spirit. The announcement of the next PlayStation command has arrived just after we saw what it will be ‘in the live’Mortal Kombat: Legacy Collection‘, a compilation that will arrive this year PS4 and PS5 with multiple games of the 90 and 2000. In those years, many played this type of titles in recreational halls, with their unmistakable physical controls. Now Sony wants to approach that experience, but with the power and capacities of its new generation console. That is where Project Defiant enters the scene, which is presented as “the first wireless fighting joystick designed by Sony Interactive Entertainment.” Its purpose is clear: to improve the experience in fighting games, but without cables in between. With PlayStation Link technology. Sony assures that its next command will feature PlayStation Link, which will offer ultrabaja latency. The good news is that it will also be compatible with PS5 and PC through cable connection. The key is in customization. The control includes interchangeable limiters without tools (square, circular and octagonal), buttons with mechanical switches and a tactile panel similar to that of the wireless control Dualsense. In terms of design, it presumes a robust construction and ergonomic lines that will touch to test when we have it in hand. The promise? Provide comfort even in the most demanding combat sessions. Bandolera type transport case included. The product will arrive with a case that will easily take it anywhere. The interior will include a dedicated space for the lever, designed to protect the Joystick Digital during transport. It is not yet for sale. Although PlayStation has already announced the device, we still do not know its price, its exact launch date or its final commercial name. Project Defiant, for now, is only the name in key. The positive part is that Sony has left some clues. He has confirmed that his launch is scheduled for 2026 and will share more details in the coming months. Now we just have to wait to check if this new command manages to make a hole in our living room. Images | Sony In Xataka | PC Soccer 8 is not just an eternally postponed video game: it is the chronicle of a legacy for the soils

brings us closer to a nuclear spatial war

by

The antimisile shield that Donald Trump wants to put in the land orbit has triggered a forceful reaction of the Kim Jong-un regime. The word is Nuclar. The North Korean Foreign Ministry has described the Golden Dome project as “the height of arrogance and arrogance”, according to North Korean state media. The Pionyang cabinet accuses Washington of being “determined to militarize the outer space,” and warns that the initiative It could trigger “a global nuclear and spatial arms race”, turning the earth’s orbit into “a potential nuclear war field.” What is the Golden Dome. An antimile shield that, despite its name Inspired by Israel’s iron domewould use multiple layers of detection and interception “by land, sea and space”, including a network of sensors and interceptors deployed in orbit, such as a satellite constellation. So ambitious is the project that, as announced by Trump and its Secretary of Defense, Pete Hegesh, would mean a “generational investment.” The White House has spoken of 175,000 million dollars over three years to be operational before 2029. The Congress Budget Office estimates that only space interceptors could cost up to 542,000 million dollarswith a two -decades deployment period. The promise is ambitious. A shield capable of demolishing hypersonic, ballistic and cruise missiles, even if they are thrown from the other side of the world or from space, in all phases of attack. Technology would be based on both existing systems and new developments. According to Reuters, a consortium led by Spacex, Palantir Technologies and Anduril Industries leads the race To display detection satellitesbased on the Starlink constellation. The hypothetical armed satellites for missile interception from space are the technologically most challenging and mysterious part of the project, among other things because they would have to be resilient to attacks with anti -attack weapons, that several powers have. An armed space. North Korean critic of the Golden Dome resonates with China’s, which Last week he expressed His “serious concern” for the “strong offensive implications” of the American antimile shield. Beijing accuses Washington of seeking “absolute security for itself” under a “United States first” policy, which “undermines global strategic balance and stability.” However, countries such as China and Russia have also advanced positions in the militarization of space, with satellites that pursue other satellites, secret deployments and spy spy airplanes. Image | White House Archives (2019) In Xataka | Russia, China and North Korea have hypersonic weapons. The US has decided to defend itself with its own iron dome

Log In

Forgot password?

Forgot password?

Enter your account data and we will send you a link to reset your password.

Your password reset link appears to be invalid or expired.

Log in

Privacy Policy

Add to Collection

No Collections

Here you'll find all collections you've created before.