There is a luxury development in Madrid that has been “hidden” for years and is stealing the spotlight from La Finca and La Moraleja

by

If we think about luxury developments in Madrid, names like La Finca or La Moraleja probably come to mind. However, there is a new player on the Madrid luxury real estate board, one that has gone unnoticed for decades and has recently become fashionable among the richest. Low profile. Álamos de Bularas is an urbanization that has been standing since the 1980s, but has gone unnoticed in the shadow of more high-profile names such as its neighbor La Finca. Its strong point is precisely that: combining luxury and exclusivity with a lower profile and less media noise than other areas. But just because it is not the most famous urbanization does not mean that it does not offer high-level luxury; a search on housing portals most popular returns us a few properties that border and even exceed 4 million euros. Tranquility is what is most sought after. Like other luxury developments such as La Finca, Somosaguas or Monte Alina, our protagonist is located in Pozuelo de Alarcón (which by the way is the richest municipality in all of Spain) specifically in the northwest area. Álamos de Bulara is a fairly small urbanization, located next to Monte del Pilar, a forested area of ​​about 800 hectares. Access is closed and has private security. The location factor. In statements to the AD Magazinethe head of the Ketier real estate agency highlights that location is a key factor for more and more buyers to look at Álamos de Bularas. The urbanization is very well connected, with access to both the M40 and the A6, allowing its residents to be in the center of Madrid in less than half an hour and in the center of Pozuelo in just 10 minutes. In addition, it is very close to some prestigious private schools and sports clubs. The new refuge for VIPs. The housing crisis is also impacting how and where the wealthiest shop. We were recently talking about luxury apartments in Madrid were so expensivewhich urbanizations like La Moraleja or La Finca were becoming more “affordable” options“for the great fortunes. According to a Colliers report A year ago, the square meter in neighborhoods such as Salamanca or Chamberí reached peaks that exceeded 27,000 euros per square meter. This has caused many buyers to seek residence in peripheral areas, where demand has increased. In Xataka | The rich neighborhoods of Madrid and Barcelona have changed their accent: millionaires from the US and Mexico invest their fortunes in Spain Image | Max Vakhtbovych, Pexels

We have not understood for decades why chronic pain punishes women more. Finally we have the answer

by

Historically, medicine has grappled with an undeniable gender gap in which women Women suffer chronic pain more frequently than men, and on top of that their pain flares for much longer. This is something that many doctors have considered ‘normal’ and has been dismissed with psychological biases. But now science has seen that an explanation should not be sought in the mind, but in the immune system. Against pain. This is the objective that medicine has right now, since it is undoubtedly a situation that for many people can be unbearable. That is why the magazine Science Immunology publish now a new study that offers a paradigm shift in our understanding of the biology of pain. The result of this is that he has managed to find the key to some types of white blood cells called monocytes and in its direct relationship with testosterone. What’s happening? When an injury is suffered, such as a blow, the body tries to defend itself with an inflammatory response. One of its components is pain, which is a necessary alarm signal to warn that something is wrong, but once the tissue begins to heal, it is logical that this alarm goes off. But this is where the body’s defense cells come in, monocytes, which act as ‘firefighters’ by releasing proteins called interleukin-10. Here the research team has been able to see that this interleukin-10, abbreviated as IL-10, acts directly on sensory neurons to “turn off” hypersensitivity and therefore pain. The problem, and here lies the importance between sexes, is that men resolve this inflammatory pain much faster because they produce a greater amount of this protein. The reason. Testosterone. This male sex hormone stimulates monocytes to produce higher levels of IL-10 after injury, and therefore pain can be better reduced. But in women this level of testosterone is much lower, and therefore the production of this natural ‘painkiller’ is lower, which causes the sensory neurons to take much longer to stop giving the signal that generates pain. Your demonstration. Beyond doing so in animal models, the research team has been able to validate the experiments with human data from the AURORA studiowhich is a project that evaluates patients who have suffered traffic accidents and severe trauma. Here the clinical data confirmed the laboratory’s suspicions, since they saw that the elimination or reduction of IL-10 activity in monocytes significantly delays the resolution of pain in both sexes, validating that this hormone-mediated immunological difference is exactly the same in humans. In the future. This discovery is not just another biological curiosity to close a historical debate, but it has important therapeutic implications. And right now the severe pain crisis has to be treated with opiates on many occasions, which have a long list of side effects. But upon discovering this cellular mechanism, the researchers tried administering Resolvin D1a compound that promotes the resolution of inflammation. Here it was clearly seen how pain was reduced equally in both sexes. This is why we are at the gateway to a new generation of non-opioid therapies that specifically modulate the immune system. But what is most important about this study is that it highlights the need to leave behind the “one size fits all” model in medicine to move towards more personalized medicine. Images | Redd Francisco In Xataka | Medicine has been using opioids to relieve pain for centuries. Science finally has an alternative

It is capable of compressing space and time

by

15 meters deep, in a basement of Zhejiang University, China has installed a machine the size of a building capable of doing something hitherto impossible for a laboratory: reproducing in hours what nature takes centuries to build. Or destroy. Its name is CHIEF1900 and it can rotate at extreme speeds or generate a gravitational force a thousand times greater than that of the Earth, which for example serves to simulate an earthquake and its effects. Context. For a geology professional, analyzing a portion of land means deciphering the history of the planet in layers: each stratum is a record of millions of years. The problem is that nature writes it slowly. Reproducing this phenomenon in a laboratory has been one of the great challenges of experimental physics for decades. Hypergravity centrifuges are the tool that comes closest to that goal. These machines are capable of rotating at extreme speeds, generating forces hundreds or thousands of times greater than Earth’s gravity. When rotating, the arms generate outward pressure on everything inside the machine. The faster it is, the greater the force. The result is a controlled hypergravity field that compresses time and distance. What China has achieved. Zhejiang University (Hangzhou) has completed the construction of the most powerful hypergravity centrifuge in the world: it will have a total capacity of 1,900g·ton, that is, it can apply 1,900G to a one-tonne sample. The CHIEF1900 will surpass the record that China had established a few months before (September 2025), with the CHIEF1300. This power makes it possible to replicate land deformations on a kilometer scale, simulate the transport of pollutants over millennia, evaluate the resistance of a dam to an earthquake or generate thousands of new material samples. As a reference, with the CHIEF1300 they have already been able to reproduce the pressure of the seabed at a depth of 2,000 meters to evaluate the extraction of methane hydrates, or simulate how a 20-meter tsunami affects the seabed. Why is it important. To natural disasters such as earthquakes or tsunamis we have to add other consequences of human activity such as the breaking of dams, contamination of aquifers or deformation of the soil under high-speed infrastructure or the melting of glaciers. Predicting how these phenomena will behave requires information that is not available since obtaining them in real conditions is either impossible or would take decades. Dan Wilson, deputy director of the Center for Geotechnical Modeling at the University of California, explains for Popular Mechanics that this will be one of the four largest dynamic centrifuges in the world, that is, it can simulate active earthquakes using hypergravity. Chen Yunmin, chief scientist of the project, sums it up accurately: It aims to create experimental environments spanning from milliseconds to tens of thousands of years, and from the atomic to the kilometer scale. How they have done it. To build a machine with such performance, Zhejiang University brought together a multidisciplinary team that brings together personnel specialized in civil engineering, thermodynamics or automation. Among the technical challenges they faced was heat: at high rotation speeds, the centrifuge reaches such temperatures that the stability of the system is compromised. The solution was a cooling system that combines vacuum, forced ventilation and glacial coolant. The fact that the installation is buried has an explanation: it minimizes external vibrations, which could contaminate the experiments to be carried out. Pending subjects. Although the installation dates back to the end of 2025 and Popular Mechanics mentions which is already operational, no scientific results from CHIEF1900 are yet available. At an operational level, these scale models reproduce the loads well but not always all the size effects: certain material behaviors do not scale linearly under hypergravity, which requires caution in the interpretation of results. To minimize this risk, it is common for the data obtained to be compared with that of other similar facilities around the world. In Xataka | China has taken a silent step in the new space race: the world’s first system to measure time on the Moon In Xataka | It’s not a telescope, it’s a time machine: what James Webb reveals to us about “deep space” Cover | Peter Herrmann and Arthur Wang Xinhua

why the United States needs the old continent more than it admits

by

That the United States is the absolute reference of the West is a reality that we have been seeing all our lives: American Way of Life from the 1950s to the hackneyed phrase “without us, you would all be speaking German” that Trump took it upon himself to remember in Davos and that we have seen countless times in war films. Spain has its own version of that story with Welcome, Mister Marshall. But Trump returned to the White House willing to fulfill his promise to “Make American Great Again” at any price: immigration management with ICE as the executing arm about their citizenship, threats to Greenland or tariffs as a tool of permanent pressure. His ways are more reminiscent of a school bully than of a leader running one of the most powerful countries on the planet. And Europe? Well, between caution, diplomacy and even turning the other cheek. The million-dollar question is whether Europe has as little room for maneuver as it appears. The answer, according to a recent analysis from the German institute Dezernat Zukunft, no. United States > Europe. In case it was necessary to remember the power of the United States in general, it has the largest GDP in the world according to the IMFit is also the country with more military spendingthe dollar It is the world reserve currency par excellence since 1945. Furthermore, leads in digital infrastructure and semiconductors (in design and sales), almost half the world share. In fact, as Dezernat Zukunft points outnot even the 10 largest European countries combined compete with those key indicators of material power. But power is not negotiating ability. The United States is the strongest in the yard, but Europe has the leverage. And here the game board changes. A close example: the gas key. Russia’s GDP It is less than the ninth part of the EUbut Russia has something that Europe needs: the gas required to heat in winter. Changing suppliers overnight was unfeasible. Europe is a succulent client. The magnificent seven (Apple, Amazon, Microsoft, Alphabet, Nvidia, Tesla, Meta) have an important part of their market in Europe. According to estimates by Dezernat Zukunftthese big tech companies generate more than $500 billion annually in Europe alone. If the old continent closes the market or fines them, their stock market shares would suffer a severe blow. And this point is not only important for companies. The magnificent seven They represent a third of the entire S&P 500the index in which the pension plans of millions of Americans are invested. If these big tech companies lose Europe, North American seniors earn less when they retire and that can be dramatic on a social and political level. Europe controls nuclear fuel. On Donald Trump’s roadmap Nuclear power plants are being built everywhere, but the United States does not have enough enriched uranium to supply itself in the short or medium term. Europe, through companies such as Urenco and Orano, is the main supplier of enriched uranium to the US, according to data from the Energy Information Agency. If the EU turns off the tap by prioritizing its own supply, the United States would have a problem meeting its nuclear needs, a key element for powering AI data centers. Because in the artificial intelligence race, The US desperately needs energy. Europe manufactures the turbines. To achieve enough electricity to meet the demand of data centers for AI, a specific type of gas turbines (40 – 60 MW) is also needed and here a European company is the queen: Siemens Energy. Siemens Energy’s SGT-800 has delivery times of one to three years, in a market where general deadlines have skyrocketed to seven years due to the demand for data centers, according to Utility Dive. Europe does not even need to turn its back on the United States, prioritizing its own orders would be enough for US artificial intelligence projects to suffer a few valuable years of delay. And time is money: the cost for large US technology operators could exceed 50 billion euros, according to Dezernat Zukunft estimates. American debt is fragile. The US dollar accounts for 58% of world reserves, but its weight as a reserve currency has been declining for two decades. USA accumulate a deficit of 1.8 trillion dollars annually that is financed by issuing debt and needs buyers. The problem is that central banks have stopped buying that debt: now it is speculative investment funds based in London that support the market. For the German institute, Europe has regulatory tools to discourage the purchase of American debt and favor European debt. If American bond rates rise, mortgages, credit and public spending in the US become more expensive. And we have seen it recently: when 30-year bonds exceeded 5%, Trump backed down in their tariffs. Europe is the best customer for gas. USA is the main supplier of LNG to the EU. However, if war conflicts allow it, starting in 2027 The International Energy Agency plans a gas surplus that will change the balance: sellers will need buyers and not the other way around. Dezernat Zukunft explains that due to geographical proximity, Europe is the best customer for the US, so if the United States tried to use gas as a weapon, it would be making a fatal mistake: it would sink the profits of its gas industry and Europe could buy gas from other countries. In fact, the EU is already working on it. Who needs who more. Although from an objective and abstract point of view parameters such as the largest army or the most powerful economy make Europe look weaker compared to the United States, Dezernat Zukunft highlights one power: that of necessity. And on some issues, the US needs Europe as much or more than Europe needs the US. It is not that Europe does not have cards to play, it is that it is difficult for it to agree to play them. In Xataka | Europe has realized that it cannot … Read more

2026 seems to be the year

by

The highway that passes through the Guadalhorce Valley and the Serranía de Ronda has been making little progress for more than a decade. And it is a shame, because it is an infrastructure that aims to alleviate all the traffic on the Málaga-Campillos-Ronda axis. The good thing is that there is beginning to be movement in the project. In fact, there are already contracts awarded and works that, if nothing happens, should begin this year. A half highway. The A-357, known as the Guadalhorce highway, connects Malaga capital with the Guadalhorce Valley and the interior of the province. It has 69 kilometers in total, but it is only a highway until Casapalma. From there, the conventional road has to support the more than 25,000 vehicles per day, although in the sections closest to Malaga the peaks reach 80,000. It is the only entrance to the capital for municipalities such as Álora, Pizarra or Cártama, and also the most direct access to Ronda for thousands of tourists and residents. Awarded in 2010, but never built. The first pending section, between the Casapalma and Cerralba interchanges (just 4.2 kilometers), was awarded for the first time in January 2010. The works, however, never began. The contract was paralyzed since then, and from the Junta de Andalucía they counted that the administration had to end up resolving it a decade later with an additional financial cost of half a million euros. The project had also become technically obsolete: since when it was restarted they had to invest money and effort in repeating the environmental procedure and updating all the documentation from practically scratch. The offers arrive. In February 2024, the Ministry of Development reactivated the project and in the summer of that same year the Government Council authorized the expense. In July 2025, The works were tendered for 56.9 million euros with an execution period of 46 months. At that time, 22 proposals were presented, most of them in the form of a UTE (temporary union of companies), with some of the largest construction groups in the country such as Acciona, Ferrovial, Dragados, Sacyr or FCC, among others. The UTE of Copisa Constructora Pirenaica and Arpo was the one who took the lead. According to Diario Surthey offered to do the work for 41.6 million, almost 15 million less than the bidding budget. What exactly is going to be built. The new section runs largely parallel to the current road, which will be maintained as a service road for local access. The new infrastructure will have a dual carriageway with two 3.5 meter lanes in each direction, shoulders and a ten meter median. It will also have a 250-meter viaduct to cross the Rio Grande. The section ends by connecting with the current highway in Pizarra through a roundabout, leaving the junction ready for the next phase. And now what. The works should start in the coming months. But this section is just the beginning. The Board has two other projects in the drafting phase that total eight more kilometers: the Cerralba-Zalea section and the duplication of the accesses to Ronda on the A-367, both awarded for design in January 2025, according to account South Journal. Beyond that, the more than 70 remaining kilometers to Ronda remain without a date or definitive route, and several groups have been asking for a clearer commitment for years. We’ll see how everything turns out. In Xataka | At 150 km it is the longest urban axis in the world and it is, to no one’s surprise, in China: connecting cities is the least important thing

Tired of being told that philosophy was just opinions, one guy set about collecting all the “philosophical facts” he could find. He got 200

by

Philosophy has a reputation for discussing everything and the truth is that it is a reputation that has been hard-earned. However, it is not a matter of saying the first thing that comes to mind. It’s not even a matter of opinions, no matter how informed they may be. At least, that is the opinion of philosopher Bryan Frances. In fact, Frances is convinced that, in reality, philosophers only discuss details and minutiae: in substance, they agree on almost everything. But of course, it is not enough to say it: it must be defended. So he began to do something strange for a philosopher: instead of arguing it, he began to compile this enormous core of shared truths. That is, to make a list. But let’s start at the beginning. Frances’s thesis is that, as I say, there is great agreement among philosophers about the truth of many substantive claims. What’s more, he is convinced that, in philosophy, there is progress equivalent to that of any other science. That is, “based on facts.” The thing is that discipline — for better or worse — tends to revolve around the controversial. The curious thing is that he realized that not even the philosophers themselves were aware of this. And what a list… So, neither short nor lazy, he published ‘Philosophy as Fact-Based Discipline: 200 Philosophical Facts, published in Philosophical Studies‘: the list. A list of elementary truths pedagogically comparable to introductory science material. “It’s not the deepest,” but it’s (definitely) something cumulative and useful to understand. But, beyond that, it is also a way of reclaiming the discipline in a climate that repeatedly questions the role of the humanities in the body of knowledge. And what truths are those? Once we have made it clear that it is not about talking about deep truths (Does free will exist? Why being and not nothingness? etc…), the question becomes evident: what are they then? They are simpler things like, for example, what beliefs are (which come in many formats, they can be about almost anything or they can exist even if we are not aware of them), what evidence is (which are not just tests), what biases, emotions or faith are. It’s very interesting review the 200 facts because there are very interesting things about things that one had not asked: does believing in something make it true? Does the evidence have direction? Is suspending the trial a rational thing to do? Thought in action. But beyond the facts themselves, Frances’ idea is intelligent because it points to something singular: there is cognitive progress, an ultimate structure of reality to describe, a philosophical ‘holy grail’ to find. It’s not much, I admit. But the idea that the universe is not the horrible chaos it seems is (in its own way) comforting. Image | Alan Dela Cruz In Xataka | “A place of joy with pain”: the phrase that summarizes the Aztec philosophy to be happier in this life

get Nextory with Xataka Xtra

by

At Xataka we always say that technology must be at the service of what we like. And in the newsroom we are very fond of devouring stories, both on screen and on paper and, increasingly, also from our headphones. Therefore, among the advantages of being part of Xataka XtraToday we want to talk to you about Nextory. If you join our community of subscribers, you have access to a Exclusive 45-day free trial period to enjoy its entire catalogue, with up to 20 hours of reading and listening included. Everything you will find in Nextory Sometimes we want to read, but we don’t have our hands free. Other times, we want to disconnect and take advantage of those dead moments on the subway or while we train. Nextory is a great option for those cases: 1.4 million options: A catalog of more than a million audiobooks, e-books and magazines. It is renewed often and you will find newly published books. The entire Planeta catalog: If you are a fan of great national and international authors, they have the complete catalog from the Planeta publishing house, with hits such as The City of Dead Lights by David Uclés or The Last Secret by Dan Brown. Compatible with all your devices: You can use Nextory on your smartphone or tablet, so you can take advantage of those gaps wherever you want to continue with the stories you have halfway done. Why try it now? The advantage of these 45 days free for the Xtra community is that they allow you to explore the service at your own pace and without pressure. Unlike the standard 7-day period, here you have a month and a half to delve into the catalog and see if it is for you without having to pay a subscription that starts at €7.99 per month. From my own experience, I tell you that it is ideal for training (I neither confirm nor deny that I have lengthened training sessions just to keep listening), traveling or for keeping up to date with magazines and books without accumulating paper. Join Xataka Xtra and start reading In Xataka Xtra We not only want you to be well informed about technology, but also to have access to tools to enjoy your free time. Nextory is a great companion for any xatakero who always has a long “to-read” list. Join ustake advantage of your 45 days gift and discover other options to read the stories you like. In Xataka | Best eBooks. Which eBook to buy and 11 recommended models

The ugliest and most hated building in Paris is its only skyscraper. Since they cannot demolish it, they have come up with another solution: make it invisible.

by

For more than half a century, the Paris skyline has remained practically frozen. You may not have realized it, but in the historic center practically no building can exceed seven floors. This norm was born after a controversial construction of the seventies that provoked such public rejection that it changed forever the urban rules of the city. Today, that architectural experiment is once again at the center of the debate. And they have found a solution. The tower that should never have existed. In a city famous for its uniform horizon of six or seven-story stone buildings, the dark silhouette of the Montparnasse Tower It has been breaking the visual harmony of Paris for more than 50 years. Inaugurated in 1973 with 59 plants and nearly 210 meters high, the mass was born as a symbol of progress in a capital that was trying to modernize after the post-war period and transform the deteriorated Montparnasse neighborhood into a business district. The project had the political support of President Georges Pompidou and the Minister of Culture André Malraux, and had to demonstrate that the city could hug “the modernity of electricity”, fast trains and telecommunications. However, the result was an enormous monolith of dark brown steel and glass that stood out brutally above the urban fabric of the 19th century, almost immediately becoming the building most hated in the capital. Aging too quickly. As usually happens in hyperbolic projects that do not end well, the problem started even before that the tower was finished. The plan had been conceived in the fifties, but could not be started until the end of the sixties due to lack of technology, money and experience to build a skyscraper of those dimensions in Europe. When it was finally built, its late modernist aesthetic already seemed dated, and its dark color (compared by some critics to a nicotine stain) contrasted violently with classical Parisian architecture. It almost instantly became a crooked line of the capital. The black sheep. The public reaction was so negative that just four years after its inauguration, the City Council prohibited building buildings of more than seven floors in the city center, pushing out the skyscrapers towards the business district of La Défense. Since then, the tower has remained an urban anomaly or, if you will, a reminder to avoid: the only skyscraper in historic Paris. The most repudiated building in the most photographed city. Over the decades, many controversial buildings in Paris ended up being accepted and even lovedfrom the Eiffel Tower itself to the Louvre pyramid or the Pompidou Center. The Montparnasse Tower, on the other hand, never achieved reconcile with the Parisians. Jokes about its presence became part of popular culture: many say that the best view of Paris is from your viewpoint because it is the only place from which the tower cannot be seen. Others describe it as the box in which the Eiffel Tower arrived packaged. Even local politicians have called the building of “urban catastrophe”and for years proposals arose to tear it down completely. However, despite widespread rejection, the skyscraper has also maintained a curious cultural life. For example, the famous “French Spiderman” Alain Robert climbed the towerand has also appeared in movies and continues to attract tourists who climb to its observation platform to contemplate the city. An impossible demolition. You may be thinking about it. If Paris hates its own creation, why the hell hasn’t it been knocked down? As tempting as the idea of ​​removing the tower from the Paris skyline is for many, tearing it down was never an option. a realistic option. The reason? The building still houses offices, has a huge commercial infrastructure at its base and its demolition would involve a gigantic cost in addition to enormous logistical and environmental problems. Even those who would like to see it disappear acknowledge that it would be financially unviable. The tower is too big, too complex and too integrated into the neighborhood to simply erase it from the map. This reality forced the city and the promoters to look for an alternative solution: If the most hated skyscraper in Paris could not be destroyed, we would have to try to transform it. EITHER directly delete it. The solution: make it disappear. From this paradox was born one of the most ambitious urban renewal projects in the city. Because the strategy is not to demolish the Montparnasse Tower, but to radically alter your appearance so that, in essence, it is not “seen” and stops dominating the Parisian horizon. The plan, promoted by a consortium of French architects and accompanied by the remodeling of the surroundings designed by Renzo Pianoaims to replace the dark façade with a kind transparent crystal leather crossed by garden terraces, balconies and vertical gardens that visually fragment the volume of the building. The idea is quite clear: lighten its presence to the point that the gigantic brown block stop imposing yourself about him skyline. A “trick” worth 700 million. The transformation of the tower and the entire urban complex that surrounds it will exceed 700 million of euros and aims to convert a degraded environment (marked by an almost abandoned shopping center and an unwelcoming concrete platform) into an open space with squares, pedestrian walkways, green areas and new connections with the neighborhood. In this way, the tower will retain its structure original plan to reduce carbon emissions during construction, will incorporate more efficient energy technologies and add high-rise gardens and a rooftop greenhouse. The project has been caught for years between political debates, neighborhood concerns and architectural discussions, but the closure of the building to evict the tenants now opens the door to start of works. The strange fate of the Montparnasse mass. In short, more than fifty years after that giddy inauguration, the Montparnasse Tower is still being an anomaly repudiated in the city that banned skyscrapers after their construction. Paradoxically, that same singularity has also turned it into a species of unintentional icon … Read more

Why does your refrigerator dry out food and when is it worth buying a ‘low frost’ one?

by

Nowadays most refrigerators are “No Frost”, but… what does this really mean? Perhaps what you have heard the most is that they do not make frost, but they also have other peculiarities with respect to the more traditional models. For this same reason, today we are going to review the differences between both types of refrigeratorswith the advantages and disadvantages in each case. How a No Frost refrigerator works No Frost refrigerators use fans that constantly remove the coldwhich prevents water vapor from condensing on its walls. Since there is a constant, dry air flow, moisture does not accumulate in the form of ice, which prevents us from having to remove it ourselves. In addition, many models have a system that allows you to eliminate small traces of ice if they appear. This No Frost system has some especially interesting advantages beyond not forming frost. By having a constant air flow, this cold air reaches all corners of the refrigerator equally, homogeneously, which allows all foods to be preserved better for longer. Now, it’s not all advantages. When using a No Frost refrigerator, it is advisable that we take into account that your air system is dryand by reaching all corners evenly it can dry out food, especially fresh items such as fruit, sausages or vegetables. We must also pay special attention to another point: No Frost refrigerators consume a little more because they have a resistance that heats up to melt the ice automatically. For this reason, we recommend looking at the annual consumption in kWh, and not only at the letter of energy efficiency. How a cycle refrigerator works Cyclic refrigerators (also called Low Frost either Less Frost by some brands) are the traditional ones, the traditional ones. They work through a refrigerant gas that travels throughout its circuit until it reaches the desired temperature, at which point the air flow stops. It does not work using fans, so they can generate less noise than No Frost. As the cold of these refrigerators is humid and they do not have a fan that constantly stirs the air, plaques of frost can form on the walls, which forces us to remove them manually so as not to compromise their efficiency and durability. Additionally, if too much frost forms, the refrigerator motor may have to work harder, which means possible increase in electricity bill. The good thing about these refrigerators is that by having a system that generates humid cold, food is usually better hydrated, preserving it better for longer. This occurs especially in fresh foods such as vegetables, which hold up better without drying out. The good of both worlds We can also find refrigerators that bring together the best of both worlds: hybrid refrigerators. In this case, they come with both systems, but separate: the No Frost system in the freezer and the cyclic system in the refrigerator. This prevents frost from forming in the freezer and allows the fresh food in the refrigerator to stay moist for longer. In other words: mixed models come with a No Frost freezer which prevents us from having to chip away at the ice that forms every so often and they also have a cyclical or dynamic refrigerator that prevent fresh foods, such as lettuce, from drying out. The good and the bad of both options, face to face No Frost Cyclic (traditional) THE GOOD 🟢 You do not need to remove the ice manually, the temperature is more homogeneous on all shelves and the food tends to cool faster thanks to the fan air system. They keep food fresh for longer and are usually quieter and cheaper. THE BAD 🔴 Their dry air can dry out fresh foods and they tend to be noisier due to the operation of the fan. Plus, they tend to be more expensive. They can form frost on your walls and can cause uneven temperatures on different shelves. Ideal for: Storing a lot of food in the freezer without the ice blocking the drawers or for families that open and close the freezer constantly, thus recovering the optimal temperature in a short time. Eat a lot of fruits or vegetables without losing moisture in a short time or if you want a refrigerator that makes little noise. We do the math to see which one can compensate you more. Each of the refrigerators has its advantages or disadvantages, so to see everything much clearer we are going to give a couple of practical examples. If you are looking for a refrigerator that allows you to use it without further ado, without worrying about removing frost every few months, a refrigerator with a No Frost system will compensate you much more. Actual use: Let’s say you usually freeze a lot of food. The accounts: No Frost refrigerators allow you to better recover the temperature by opening and closing the freezer many times. In addition, you avoid emptying it to defrost the ice every few months. So? It is a choice that lies in both the comfort and the usefulness of the freezer: fresh foods dry out more, but in exchange we have a freezer that better maintains its ideal temperature. If you opt for these refrigerators, at least have one or more drawers with humidity control, generally called VitaFresh or BioFresh. Although there are fewer of them in stores today, refrigerators that are cycled or have a traditional system can be very attractive, both for the preservation of certain foods and for other characteristics. Actual use: You don’t usually freeze a lot of food and you usually eat a lot of it fresh. The accounts: Having a cycle refrigerator allows fresh food to last better. In addition, by not using a fan constantly, they tend to make less noise. So? It is ideal if you consume more fresh foods than frozen foods or if you have the refrigerator next to, for example, the living room and you are looking for as little noise as possible. … Read more

We have found the “switch” of cellular aging. The secret is called protein AP2A1

by

Regenerative medicine has a very clear objective ahead today: to look for the ‘button’ that can stop aging and allow us live much longeror at least have a better quality of life when we reach certain ages. And here the Japanese have a lot to say with a discovery that gives us more clues about how to preserve our cells much better. A new study. Everything that has to do with living a little longer, the truth is that it causes a little stir in the scientific world, and the article published in January 2025 in the magazine Cellular Signaling it was no wonder. Here it was shown how a team of researchers from Osaka University managed to identify a protein that literally acts as a cellular senescence switch called AP2A1. Our cells. Just as aging can be seen aesthetically, our cells also age through a process of senescence. Upon entering this state, the cells stop dividing, but do not die, since they become larger, more rigid and adhere strongly to their environment. And here a team of scientists has discovered the exact mechanism that causes this. Here the study has pointed to a protein as the culprit: AP2A1. A molecule that acts as a kind of biological transport truck that moves another protein, called β1 integrin along the fibers of the cell. That is why, over time, this process strengthens cell adhesion, causing the cell to become rigid and “old.” The revolution. The important thing here is that if the function of AP2A1 is suppressed in old cells, the biological clock reverses. That is, the cells decrease in size, lose rigidity, drastically reduce the classic markers of aging and proliferate and migrate again. Basically, they rejuvenate themselves. Furthermore, it has also been seen that if this protein is overexpressed in young cells, the result is great aging that accelerates. Your potential. Here the scientific team has seen that AP2A1 is not only emerging as a great marker that measures a person’s aging, but also acts as a direct therapeutic target. That is why some specialized websites such as Fight Aging! already analyze how blocking AP2A1 prevents inflammatory signaling typical of senescent cells. In this way, if we manage to inhibit this protein in the future, we could develop “anti-senescence” agents capable of extending our healthy life expectancy and combating age-related diseases, such as osteoarthritis. A long way. For now, this is something that has been estimated in cellular models in a dish in a laboratory, but it still remains to be seen how it works in the human organism with all the factors that intervene on a cell that is not isolated. What is clear is that the discovery of AP2A1 is a spectacular milestone in cell biology. We have basically found the button that controls the size and youth of cells in the laboratory, but the next big challenge for science will be to find out if we can press that same button, safely, inside the human body. And for that, there are still many years of research left. Images | National Cancer Institute Huy Phan In Xataka | While half the world is worried about aging, one industry is rubbing its hands: the elevator industry

Log In

Forgot password?

Forgot password?

Enter your account data and we will send you a link to reset your password.

Your password reset link appears to be invalid or expired.

Log in

Privacy Policy

Add to Collection

No Collections

Here you'll find all collections you've created before.