from a Nintendo Switch to air conditioning devices

Summer is just around the corner and Amazon has decided to warm up ahead of time. Although the expected Prime Day 2026 has advanced its dates in an unprecedented way and will start in a couple of weeks, this online store did not want to wait to offer discounts on technology and home. If you are looking to equip yourself for the holidays without breaking your monthly budget or need immediate solutions to combat the first heat waves, we have selected the five best deals available today on Amazon. Rowenta Turbo Silence Extreme, Standing Fan 40 cm The price could vary. We earn commission from these links Philips OneBlade 360 by 28.99 euros: with an adjustable guide comb and 60 minutes of autonomy. Robot vacuum cleaner Roborock QV 35A by 329.99 euros: with 8,000 Pa and also mops. Standing fan Rowenta Turbo Silence Extreme by 79.79 euros: with carrying handle and reinforced grille. Wireless headphones Xiaomi Redmi Buds 6 Play by 9.99 euros: light and with a battery of up to 36 hours. Nintendo Switch OLED by 323.99 euros: with seven-inch, 64 GB OLED screen. Philips OneBlade 360 Having the best image in summer is the premise of many and the beard is the “makeup” of men. If you want to have yours in perfect condition always, this Philips OneBlade 360 has already established itself as a shaver reference. Its recommended price is 59.99 euros, but now you can get it with a 52% discount, for 28.99 euros. The great attraction of this pack available on Amazon is that it comes equipped with a 5-in-1 adjustable guide comb and an additional replacement blade, ensuring months of use without spending extra. In addition, its long-lasting battery offers up to 60 minutes of autonomymaking it the ideal travel gadget to pack in your suitcase this vacation. Philips OneBlade 360 ​​Hybrid Razor (model QP2734/30) The price could vary. We earn commission from these links Roborock QV 35A Robot Vacuum Cleaner This robot vacuum cleaner of Roborock stands out for its suction power of 8,000 Pa that destroys the dust. Although if there is something outstanding about it, it is its anti-tangle technology that will be the salvation of homes with pets. On Amazon, the Roborock QV 35A now has a 44% discount, and can be purchased for 329.99 euros. It is a perfect robot vacuum cleaner model to delegate cleaning tasks and enjoy more free time in summer because it not only vacuums but also also mops. roborock Robot Vacuum Cleaner QV 35A The price could vary. We earn commission from these links Rowenta Turbo Silence Extreme Standing Fan If you don’t want to use the air conditioning so much this summer, this standing fan stands out for its balance between air power and a extremely quiet operation only 45 dB in its night mode. Now it has a 43% discount and you can get it for 79.79 eurosinstead of the almost 140 euros that it has as a recommended RRP. Its robust design includes a reinforced grating for added child safety and an ergonomic carrying handle to easily move it from room to room as needed. It is, therefore, one of the smart purchases of the season to alleviate heat waves at home. Rowenta Turbo Silence Extreme, Standing Fan 40 cm The price could vary. We earn commission from these links Xiaomi Redmi Buds 6 Play wireless headphones If you plan to travel a lot (especially by transportation this summer), a few Bluetooth headphones They cannot be missing in your travel backpack. For the tightest budgets, now on Amazon you have 9.99 euros these Xiaomi Redmi Buds 6 Play. These are some headphones button type very light and ergonomically designed. Its battery offers a range of up to 36 hours and includes noise cancellation by Artificial Intelligence for calls. XIAOMI Redmi Buds 6 Play – Wireless headphones The price could vary. We earn commission from these links Nintendo Switch OLED If you don’t want to spend the money that the new one costs nintendo switch 2 but you are looking for a console model that you can easily take anywhere without breaking the bank, this NSwitch OLED Discounted is one of the Amazon bargains that is worth it. It is now available for 323.99 euros. This Nintendo Switch OLED stands out for its seven-inch OLED screenso you can enjoy pure blacks and better contrast. It comes with 64 GB of storage and will surely become your inseparable companion on train, car or plane trips this summer. Nintendo Switch (OLED version) Neon Blue/Neon Red The price could vary. We earn commission from these links Some of the links in this article are affiliated and may provide a benefit to Xataka. In case of non-availability, offers may vary. Images | Javier Penalva (Xataka), Nintendo, Xiaomi, Rowenta, Roborock and Philips In Xataka | The best mobile phones, we have tested them and here are their analyzes In Xataka | Best quality-price air conditioners 2026. Which one to buy and seven recommended models for less than 800 euros

“My biggest fear was that everyone would switch to electric. I feel very alone”

That Akio Toyoda presides over a company with which he practically shares a name is no coincidence. The president of Toyota is the grandson of Sakichi Toyoda, founder of a Toyoda Automatic Loom Worksa machine-made loom company. That company opened its car division in the 1930s with Kiichiro Toyoda in front. The eldest son built an empire that Akio Toyoda now presides over. It is also no coincidence that Akio Toyoda has had a passion for automobiles since he was a child. And that, now, completely defines his position at the head of the company. “I feel very alone”. “I’m the only one who does it. I feel very alone.” Those are the words that Akio Toyoda has responded to Auto Expressan English media outlet that has been able to have a conversation with the president of Toyota regarding the steps the company is taking. What Akio Toyoda is talking about is your defense of the combustion engine. “Three or four years ago, he was the only one saying he loves the smell of it, he loves the sound of it, he loves the engines and he wanted to keep the engine suppliers’ jobs.” Toyoda assures that he feels very alone in this defense. The greatest fear. Asked what his worst fear is in the automobile industry, Toyoda is clear: “that everyone was switching to electric cars was my biggest fear.” And the reason, he assures, has nothing to do with being late to technology or that the path taken by Toyota was not the correct one. “If I only seek to balance the accounts and achieve profitability or if I only seek carbon neutrality… that is not interesting,” Toyoda defended. “If someone tells me, ‘hey, you’re too late, you should have gone electric sooner,’ well, we’re people who love cars and those people, including myself, have to fight within companies“he stressed. The Toyota electric. Toyota’s relationship with the electric car is nothing short of tumultuous. The leaders have always defended that the electric car it will not be the future of the automobile. Or at least will not be the dominant position in all marketswhich has marked its line of business until now. And it is that he Toyota Bz4X It was until very recently the company’s only car. It also arrived with manufacturing problems and a price that was too high, which buried its possibilities in the market. With an updatethe company has managed to skyrocket its sales and the electric Toyota C-HR also seeks to give a good boost to this part of its technology. Furthermore, the company has been announcing new releases for the coming years and has a clearly marked roadmap for the production of solid state batteries. Decisions that seem to go against what was said by its own president and that explain those statements in which he says that he himself has to fight within his company. To each market, its own. Toyota’s decision has a lot to do with practicality. When the European Union announced a roadmap to ban combustion engines, many of its manufacturers threw themselves into the arms of the electric car and announced that They stopped the development of these engines. Toyota, on the contrary, continued to bet on hybrids, aware that they would continue to be very important in the future. Time has proven them right in part because the European Union has slightly opened its hand but, above all, because our market is a very small part of global automobile sales. For Toyota, the United States remains a gigantic market where last year it sold 2.5 million cars. It is the same market that has paralyzed the promotion of the electric car. Only in Japan does it sell the same cars as in all of Europe. And in China, although he has tried to go on his owncontinues to have the obligation to associate with a local brand, so the performance of the electric cars launched there is lower. An alternative. Toyota defends that the electric car will not exceed 30% market share. We don’t know if Akio Toyoda has changed his perception since he made that statement, but he has always made it clear that solid-state batteries are the ones that can truly change the game. Until then, and like other Japanese brandsToyota continues to investigate new alternatives. Of them, hydrogen is said to be the most interesting. For now, your Toyota Mirai (the fuel cell car) remains exceptional in Europe and in US faces lawsuits over false advertising. The high cost of transporting hydrogen safely to a service station and, first, producing it makes the product too expensive, which still has no clear advantages. But Toyota has found another way to continue studying: burn hydrogen. This, they claim, allows a combustion engine to operate without expelling CO2 (although other polluting substances such as NOx) and at the same time maintain the sound and sensations typical of this type of propellant. Although It is even less efficient than the hydrogen fuel cellthat doesn’t seem to matter to Toyoda. a defense. And at this point, I’m going to make a defense of Akio Toyoda. The president of Toyota, a company that invented a new way of working and that perfected the just in time and with them their profits, he is right when it comes to defending that not everything should be done with profitability in mind. Toyota has become one of the few brands that continues to launch purely passionate cars without any specific objective. There is no car like it Toyota GR Yaris in the market, years ago they took advantage of their collaboration with Subaru to launch the Toyota GT86 (then GR86) and invested together with BMW to launch the new Toyota Supra. In recent months we have learned that they are launching a new and spectacular racing car adapted for the street, the Toyota GR GT. A few days ago they presented a radically sporty special edition of the Toyota Corolla that … Read more

There are still phones, Nintendo Switch 2 and more at a good price in the best summer promotion on AliExpress

All good things come to an end, something that we can also apply to the events full of offers that happen all year long. There are just over 24 hours left until it ends AliExpress Summer Promoa campaign that began last week and in which we have seen brutal prices for consoles, mobile phones and many other devices. The good news? There are several of these offers that are still availableyes. The price could vary. We earn commission from these links Discount minimum purchase coupon 1 coupon 3 coupon 4 COUPON 3 euros 15 euros XATAKAES03 WEBEDES03 ESSS03 SSES03 6 euros 39 euros XATAKAES06 WEBEDES06 ESSS06 SSES6 10 euros 69 euros XATAKAES10 WEBEDES10 ESSS10 SSES10 20 euros 139 euros XATAKAES20 WEBEDES20 ESSS20 SSES20 30 euros 209 euros XATAKAES30 WEBEDES30 ESSS30 SSES30 45 euros 319 euros XATAKAES45 WEBEDES45 ESSS45 SSES45 65 euros 459 euros XATAKAES65 WEBEDES65 ESSS65 SSES65 110 euros 650 euros XATAKAES110 WEBEDES110 ESSS110 – Only until tomorrow at 11:59 p.m. (or until the discount coupons run out, whichever comes first) we have access to very good deals in technology. There is not as much to choose from compared to last week, but even so we still have very good purchasing options. Here are five we love: nintendo switch 2 by 366.33 euros with the coupon ‘XATAKAES45’, a great price for the Nintendo hybrid before it increases in price. POCO X8 Pro by 262.81 euros with the coupon ‘XATAKAES30’, in its version with 512 GB of storage. Huawei Watch GT 6 Pro by 254.33 euros with the coupon ‘XATAKAES30’, a smartwatch with autonomy for up to 21 days. AMD Ryzen 7 9800X3D by 382.85 euros with the coupon ‘XATAKAES45’, a very powerful processor ideal for gaming and heavy tasks. Xiaomi TV Box S (3rd generation) by 37.46 euros with the coupon ‘XATAKAES06’, a device that could be great for an old TV. nintendo switch 2 One of the most sought after devices in this AliExpress promo has been nintendo switch 2. The hybrid of the Japanese company The price will increase next Septemberspecifically up to almost 500 euros. For this reason, while the Summer Promo lasts, we may have one of the last opportunities to take it home for much less: it comes out for 366.33 euros with the coupon ‘XATAKAES45’. The price could vary. We earn commission from these links POCO X8 Pro It is very possible that the POCO X8 Pro be one of the best quality-price phones of the year. It is a very balanced device that has a 6.59-inch screen with good maximum brightness (ideal for outdoors), a chip that offers good performance and 8 GB of RAM in this version of the device. In addition, its 6,500 mAh battery offers very good autonomy and this version has 512 GB of storage. comes out for 262.81 euros with the coupon ‘XATAKAES30’. The price could vary. We earn commission from these links Huawei Watch GT 6 Pro Autonomy is the Achilles heel of many watches, although that does not happen to the Huawei Watch GT 6 Pro. This smartwatch is capable of reaching up to 21 days of autonomy, a figure that not many devices can match. In addition, it is compatible with both Android and iOS, it has a very cool design and has many different functions, both for playing sports and for measuring our health. Costs 254.33 euros with the coupon ‘XATAKAES30’. The price could vary. We earn commission from these links AMD Ryzen 7 9800X3D If you are looking for a new processor for your PC, this Ryzen 7 9800X3D from AMD is a great option. This CPU uses the technology 3D V-Cache and it has 8 cores and 16 threads. In addition, it is compatible with DDR5 RAM, although it is true that right now is not the best time to buy it. Yes, it is to buy this processor, which remains in 382.85 euros with the coupon ‘XATAKAES45’. The price could vary. We earn commission from these links Xiaomi TV Box S (3rd generation) If you have an old TV that you don’t want to change or one where you simply don’t like the operating system, this Xiaomi TV Box S could be great for you. It offers 4K resolution and supports both HDR10+ and Dolby Vision. In addition, it has a Google TV operating system, so it will give you access to applications like Netflix or DAZN in case you plan to watch the World Cup. comes out for 37.46 euros with the coupon ‘XATAKAES06’. Xiaomi TV Box S (3rd generation) The price could vary. We earn commission from these links Some of the links in this article are affiliated and may provide a benefit to Xataka. In case of non-availability, offers may vary. Images | Nintendo, Xiaomi, Huawei, AMD, Xataka In Xataka | Best mobile phones in quality price. Which one to buy based on use and nine recommended models In Xataka | Best smartwatch in quality price. Which one to buy based on use and seven recommended models

So you can get a Nintendo Switch 2 from AliExpress!

A raffle is coming, no, a great raffle. The eighth exclusive giveaway for subscribers of Xataka Xtra It is neither more nor less than a nintendo switch 2Nintendo’s latest console. Valued at 459 euros, the Switch 2 is great now that summer is approaching and we have more free time to indulge in a big way. The draw is reserved for subscribers of Xataka Xtraour community with exclusive advantages. If you are already a member you can go to the next paragraph, because you already know how it works. If you are not yet part of All the information can be found at this link. How to participate in the giveaway for a Nintendo Switch 2 Participating in this great giveaway is as easy as being part of Xataka Xtraaccess your member area and check the box that appears in red in the image below. When you have done so, you will participate in this draw and in all those to come, which are not few. Make sure you check that box to automatically participate in the exclusive Xataka Xtra draws | Image: Xataka If you are already part of Xataka Xtra and have participated in previous draws you don’t have to do anything. You will automatically participate in the draw. As a summary and for the dates to be clear, here is a summary: Requirements: be a Xataka Xtra subscriber and resident in Spain (Peninsula, Balearic Islands, Canary Islands, Ceuta and Melilla) Start of the draw: Monday, June 8, 2026. End of the draw: Friday, June 19, 2026, at 9:00. Winner selection and resolution: Friday, June 19, 2026. How will the winner be chosen? From Xataka we will choose a random subscriber and two substitutes. If the winner does not respond within the period stipulated in the legal bases of each draw, the winner will go to the first substitute and, if this does not happen either, to the second. Winning a giveaway does not prevent you from winning in the following ones. You can find the legal bases at this link. Regarding the prize, the nintendo switch 2 needs few introductions. The new Nintendo console, which is available on AliExpress for 435 euros In the summer offers, it allows you to move Nintendo Switch games, titles such as Cyberpunk 2077 and the future Call of Dutyand other wonders like Pokopia, Mario Kart World either Donkey Kong Bananza. It is a machine that feels objectively superior in each and every one of the sections compared to the previous generation. It is a great prize to enjoy the summer in a big way, whether by making the most of the games single player like sharing the Joy-Con. Best of luck to everyone! In Xataka | Subscribe to Xataka Xtra

Switch 2 will have replaceable battery in 2027

nintendo has confirmed on its consumer information website that prepares a revised version of the Switch 2 for the European market, one in which the battery can be easily replaced. It is not really a traditional revision as we might expect, but a new version born as a result of complying with European regulations that will come into force in 2027. What is this about? The key is in the Regulation (EU) 2023/1542 on batteries, which as of February 18, 2027 requires that cells and batteries integrated in certain devices sold in the EU can be removed and replaced by the user himself easily and at any time during the product’s useful life. Portable consoles fall into that category, so the Switch 2 is fully affected. What Nintendo says. In the official publication On its website, the company assures that it is “implementing measures to comply with these requirements by preparing versions of products that comply with the Regulation.” To differentiate those models from the current ones, Nintendo says the new ones will carry different model numbers and the additional “OSM” code visible on the packaging, identifying them as “standalone products for regulatory purposes.” How affected models are recognized. Nintendo doesn’t mention the Switch 2 by name, instead talking about “current products whose model numbers start with ‘BEE’.” That is precisely the case of Switch 2, whose model number is BEE-001, as collects VGC. The Joy-Con 2 (BEE-012 and BEE-014) and the Switch 2 Pro controller (BEE-008) also have integrated batteries and share that same prefix, so they could also receive a review if the regulations apply to them. At the moment, Nintendo has not confirmed it. Details yet to be confirmed. Nintendo does not explain what will change at the design level to facilitate replacement. And it will require a major change, because nowadays replacing the Switch 2 battery is no small feat. According to the repair guide from iFixit, the battery is not accessible even after removing the back cover, and requires disassembling a large part of the device and then reassembling it. The one with the Joy-Con 2 is somewhat simpler, but it’s not easy either. Only for the EU, for now. Nintendo has not yet committed to selling these models outside of Europe, nor is it under any obligation to do so. However, as they point From Tom’s Guide, making a completely different version of hardware for a single region ends up making little economic sense. And the usual thing is that regional variants are limited to specific components, not to redesigns as important as this one. That’s why it wouldn’t be strange if, over time, the “OSM” models also end up reaching other markets, although for now it’s just a guess. When. The only certainty is that Nintendo will have these adapted consoles in European stores before February 18, 2027. What is not clear is the exact schedule or whether the original version will coexist with the new one or will end up disappearing. Nor should we lose sight of the fact that these models will arrive, presumably, after the price increase planned for Septemberwhich places the console at 500 euros here in Europe. We will have to wait to find out more information about it. In Xataka | A CD Projekt developer: “Do you know what we’re doing for ‘The Witcher 4’? People aren’t ready”

there is Nintendo Switch 2 and several PS5

In recent months, we have seen how PlayStation 5 has increased in pricesomething that has also “replicated” Nintendo Switch 2. That makes it difficult to get one of these consoles at a good price, but not impossible. For this, we have the best purchasing window right now with the new AliExpress Summer Promothanks to which we have a series of discount coupons that these consoles (and almost any device) leave us at a great price. The price could vary. We earn commission from these links Discount minimum purchase coupon 1 coupon 3 coupon 4 COUPON 3 euros 15 euros XATAKAES03 WEBEDES03 ESSS03 SSES03 6 euros 39 euros XATAKAES06 WEBEDES06 ESSS06 SSES6 10 euros 69 euros XATAKAES10 WEBEDES10 ESSS10 SSES10 20 euros 139 euros XATAKAES20 WEBEDES20 ESSS20 SSES20 30 euros 209 euros XATAKAES30 WEBEDES30 ESSS30 SSES30 45 euros 319 euros XATAKAES45 WEBEDES45 ESSS45 SSES45 65 euros 459 euros XATAKAES65 WEBEDES65 ESSS65 SSES65 110 euros 650 euros XATAKAES110 WEBEDES110 ESSS110 – These coupons, which cannot be combined, are added to an additional discount of up to 33 euros if we pay with PayPal. In this way, we can get one of the consoles that we mention above at prices that we will not find in other stores. Below, we show you how they would look applying the greatest possible discount: nintendo switch 2 by 343.54 euros with the coupon ‘XATAKAES30’ PlayStation 5 Slim by 500.99 euros with the coupon ‘XATAKAES65’ PlayStation 5 Pro by 706.05 euros with the coupon ‘XATAKAES110’ Nintendo Switch Lite by 156.90 euros with the coupon ‘XATAKAES20’ nintendo switch 2 We start with nintendo switch 2. This console is, in essence, a hypervitaminized version of the first Switch, being able to reach 4K resolution when we play on a TV through its dock. The console has only been in stores for a short time, but even so it already has high-quality exclusives like ‘Pokémon Pokopia‘or the new one’Yoshi and the Mysterious Book‘. The console will increase in price in September to 499.99 euros, but now we can get it for 343.54 euros if we use PayPal and the coupon ‘XATAKAES30’. The price could vary. We earn commission from these links PlayStation 5 Slim PlayStation 5 It will not wait until after the summer to increase its price and its version with a disc reader already costs 649.99 euros. However, the AliExpress Summer Promo has it available with shipping from Spain for 500.99 euros with the coupon ‘XATAKAES65’ and paying with PayPal. It is a great price if we take into account that it has been difficult to find it on sale lately, even now that we have assets a few Days of Play. The price could vary. We earn commission from these links PlayStation 5 Pro If you prefer to opt for the best of Sony consoles, then you have this PlayStation 5 Pro by 706.05 euros with the coupon ‘XATAKAES110’ and paying with PayPal. It is a great price if we take into account that its RRP right now is 899.99 euros. It is a more powerful version that, thanks to PSSR 2, allows for better gaming performance. It also has 2 TB of storage, which is a plus if you have a lot of digital games. In fact, this console comes without a disc reader, although you can buy it separately. The price could vary. We earn commission from these links Nintendo Switch Lite Are you looking for an even cheaper console? Then the Nintendo Switch Lite is an ideal option for you. It is true that its hardware is more limited than the rest of the options on this list and that this version cannot be used connected to a TV or monitor, but in exchange it has a brutal price (it costs 156.90 euros with the coupon ‘XATAKAES20’ and paying with PayPal) and its video game catalog is enormous, with gems like ‘Super Mario Odyssey‘ either ‘The Legend of Zelda: Tears of the Kingdom‘, among many others. The price could vary. We earn commission from these links Some of the links in this article are affiliated and may provide a benefit to Xataka. In case of non-availability, offers may vary. Images | AliExpress, Xataka, Nintendo, PlayStation In Xataka | Best wireless over-ear headphones. Which one to buy and five recommended models In Xataka | DDR4 or DDR5? What RAM to choose so as not to pay even more than necessary in the middle of the price crisis

We have found a hidden “switch” of Alzheimer’s. And the best thing is that we have promising candidates to put it out

Alzheimer’s is still one of the biggest medical challenges of our century, since we are facing a disease with a very important incidence and above all that entails a large number of social problems around it. Here research over the decade has focused on the accumulation of protein plaques beta-amyloid in the brain to explain it. However, the scientific community has begun to pay much more attention to an equally devastating factor: neuroinflammation. A new gene. Science continues to advance and one of the latest discoveries that has been made lies in the APOE4 genewhich is a known risk factor for Alzheimer’s disease. And it is no wonder, since people who inherit this variant have a much higher probability of developing the disease, and often do so at younger ages. But now a research team has been investigating exactly why having this genetic variant predisposes one to Alzheimer’s, and the answer appears to lie in chronic inflammation. More specifically, in APOE4 carriersthe brain’s immune system overreacts, creating a toxic environment that damages neurons and accelerates cognitive decline. And at the center of this inflammatory storm, researchers have indicated to the enzyme cPLA2 as the main culprit. It’s a challenge. Knowing that cPLA2 plays a crucial role in the inflammatory cascade associated with Alzheimer’s, the objective is logically set turn it off permanently. However, inhibiting enzymes in the brain is not an easy task, since the brain is very well protected by the blood-brain barrier, which acts as a true customs control that allows only some very selected elements to pass through. That is why creating a drug that passes through it without causing side effects in other parts of the body is a great challenge. The strategies. To reach this goal, science is now doing computer simulations of thousands of molecules to be able to find those with the exact shape and properties to “fit” into the cPLA2 enzyme and deactivate it. Once this ‘key’ that fits the enzyme that looks like a lock is identified, candidate compounds can be refined for testing in animal models. Until now, research already has several selective cPLA2 inhibitors that have proven to be powerful and capable of penetrating the brain, making it possible to reduce neuroinflammation in the models studied. Personalized medicine. The study, supported by multiple leading institutions such as the National Institute on Aging and the Alzheimer’s Drug Discovery Foundation, is not only relevant for the design of the new drugs, but also for its personalized medicine approach. Looking back, clinical trials for Alzheimer’s have treated all patients equally, often resulting in million-dollar failures. But now, by targeting these new cPLA2 inhibitors specifically at neuroinflammation fueled by the APOE4 gene, scientists are creating tailored treatments for the most biologically vulnerable patients. Although we are still in a very early phase of research, it may take years to see a tangible result. Images | Robina Weermeijer In Xataka | Alzheimer’s no longer seems irreversible: science allows brains with advanced damage to recover for the first time in animals

New round of April savings at MediaMarkt with offers on the Google Pixel 10, the Nintendo Switch 2 and much more

As it usually does on certain occasions, MediaMarkt has once again renewed one of its campaigns to change the offers and to extend the date on which they will be available. April and save has arrived again with a new round of discounts that will end on April 23 at 9:00 a.m. Do you want to know which are the best deals? In this article we are going to review the five best deals on technology. Google Pixel 10 by 599 eurosan ideal mobile if you are looking for a good balance between price, quality and compact design. nintendo switch 2 by 479 eurosthe store’s new promotion that includes a video game and a keychain. LG OLED C5 by 999 eurosthe television that we currently recommend for its quality-price ratio. Samsung HW-Q990F/ZF by 749 eurosa fairly complete sound bar that includes wireless subwoofer and rear speakers. TP-Link Tapo P110 Mini by 10.99 eurosa practical smart plug that is ideal for turning devices on and off whether we are at home or not. Nintendo Switch 2 + Mario Kart World (physical format) + keychain The price could vary. We earn commission from these links Google Pixel 10 He Google Pixel 10 It has dropped in price through countless offers and can now be purchased for much more affordable prices. MediaMarkt, for example, has it right now for 599 euros, almost its historical minimum price (594.21 euros). Without a doubt, it is a very interesting mobile phone both for its size and performance, but also for its construction and its photographic section. The price could vary. We earn commission from these links nintendo switch 2 MediaMarkt is one of the stores that has launched the most offers and promotions in the nintendo switch 2and now it has arrived with a very interesting new one: it costs 469 euros (recommended price), but if you go down a little in the store you can buy a pack for 479 euros which includes the ‘Mario Kart World’ in physical format along with a keychain. This pack is especially interesting because it is very similar to the one officially launched by Nintendo, except that The video game in this case is in physical format, includes a keychain and is much cheaper. Nintendo Switch 2 + Mario Kart World (physical format) + keychain The price could vary. We earn commission from these links LG OLED C5 What is the television with the best quality-price ratio? We are quite clear: right now it is the LG OLED C5. Its price on MediaMarkt is 999 eurosalthough you can find it cheaper on Amazon (959 euros). It is a television 55 inch OLED which supports both Dolby Vision and Dolby Atmos. It also comes with several HDMI 2.1 ports, its refresh rate reaches 144 Hz and includes some technologies gaming like G-Sync or FreeSync. The price could vary. We earn commission from these links Samsung HW-Q990F/ZF On the other hand, if you already have a good television and are looking for a very good audio experience, MediaMarkt has the Samsung HW-Q990F/ZF by 749 euros (previously 1,399 euros), a sound bar that includes wireless subwoofer and two rear speakers. Offers a 756W power at 11.1.4 channelsis compatible with Dolby Atmos and works with both Alexa and Google Assistant. The price could vary. We earn commission from these links TP-Link Tapo P110 Mini He TP-Link Tapo P110 Mini It is a very practical smart plug, especially because of the 10.90 euros What does it cost at MediaMarkt. It allows you to turn lamps or devices on and off and even create routines to turn them on. Personally, I use several every day to power power strips with many outlets (to turn them off at night via voice commands) and turn lamps on or off when it’s getting dark. In addition, the app allows us to use the plugs even if we are not at home, something quite useful in case we have left it on. The price could vary. We earn commission from these links Some of the links in this article are affiliated and may provide a benefit to Xataka. In case of non-availability, offers may vary. Images | Laura LopezCompradicción and MediaMarkt (header), Google, Nintendo, LG, Samsung, TP-Link In Xataka | The best mobile phones, we have tested them and here are their analyzes In Xataka | Best televisions in quality price. Which one to buy and seven recommended 4K smart TVs

The Xiaomi 17 Ultra at a minimum price, the Nintendo Switch 2 with a free game, offers on LG OLED TVs and more. Hunting Bargains

April has started strong in terms of number and quality of offers. Stores like Amazon, MediaMarkt or even LG itself right now have some of the most interesting discounts on technology and entertainment, so in this week’s Bargain Hunting we are going to review the best offers we have been finding in recent days. LG OLED C5 by 896.99 eurosa television with an excellent screen and a very reasonable price. Apple Watch Series 11 by 379 eurosthe Cupertino watch at the lowest price MediaMarkt has ever had. Xiaomi 17 Ultra by 999 eurosa new historical minimum price for Fnac members. HP Omen 16 by 1,325 eurosa historical minimum price for a very complete laptop for gaming. nintendo switch 2 by 459 euroswith a gift video game to choose from four options. The price could vary. We earn commission from these links LG OLED C5 If there is a particularly interesting television right now, it is the LG OLED C5whose price at the LG outlet is 896.99 euros. In this case it comes with a 55-inch OLED screen and reaches a refresh rate of up to 144 Hz, it is compatible with Dolby Vision and Dolby Atmos and its speakers offer a good power of 40W. The price could vary. We earn commission from these links Apple Watch Series 11 Apple watches do not usually drop too much in price, but there are exceptions. One of them has fallen into the Apple Watch Series 11found on MediaMarkt by 379 eurosthe new historical minimum price of the store. Among the most notable features is an excellent screen, as well as a large assortment of sensors to monitor physical activity. The price could vary. We earn commission from these links Xiaomi 17 Ultra The best offer of the week has fallen on the Xiaomi 17 Ultrawhose price has dropped in Fnac to 999 euros (500 euros discount); Yes, it is only for store partners. Regarding mobile phones, we are talking about one of the candidates to position itself as the best (or the best) of the year. It is a spectacle in photography, it is very powerful thanks to its Snapdragon 8 Elite Gen 5 processor and its 6.9-inch screen is excellent. The price could vary. We earn commission from these links HP Omen 16 The RAM crisis has caused many devices to increase in price, but many others have done the opposite. He HP Omen 16 has been dropping in price until the current price 1,325 euroswhich is its historical minimum. It is a laptop gaming with a 16-inch screen that offers 2.5K resolution. Its processor is the Intel Ultra 7 255H, it comes with 32 GB of RAM and 1 TB of SSD and its graphics card is an Nvidia GeForce RTX 5070. Of course, it does not come with Windows. The price could vary. We earn commission from these links nintendo switch 2 The nintendo switch 2 has returned to MediaMarkt with the offer that we saw at the end of March: if you buy it for 459 eurosthe store gives you a video game to choose from four different options: Nintendo Switch 2 + game to choose from four different options The price could vary. We earn commission from these links Some of the links in this article are affiliated and may provide a benefit to Xataka. In case of non-availability, offers may vary. Images | LG, Apple, Xiaomi, HP, Nintendo In Xataka | The best mobile phones, we have tested them and here are their analyzes In Xataka | Best smartwatch in quality price. Which one to buy based on use and seven recommended models

We have found the “switch” of cellular aging. The secret is called protein AP2A1

Regenerative medicine has a very clear objective ahead today: to look for the ‘button’ that can stop aging and allow us live much longeror at least have a better quality of life when we reach certain ages. And here the Japanese have a lot to say with a discovery that gives us more clues about how to preserve our cells much better. A new study. Everything that has to do with living a little longer, the truth is that it causes a little stir in the scientific world, and the article published in January 2025 in the magazine Cellular Signaling it was no wonder. Here it was shown how a team of researchers from Osaka University managed to identify a protein that literally acts as a cellular senescence switch called AP2A1. Our cells. Just as aging can be seen aesthetically, our cells also age through a process of senescence. Upon entering this state, the cells stop dividing, but do not die, since they become larger, more rigid and adhere strongly to their environment. And here a team of scientists has discovered the exact mechanism that causes this. Here the study has pointed to a protein as the culprit: AP2A1. A molecule that acts as a kind of biological transport truck that moves another protein, called β1 integrin along the fibers of the cell. That is why, over time, this process strengthens cell adhesion, causing the cell to become rigid and “old.” The revolution. The important thing here is that if the function of AP2A1 is suppressed in old cells, the biological clock reverses. That is, the cells decrease in size, lose rigidity, drastically reduce the classic markers of aging and proliferate and migrate again. Basically, they rejuvenate themselves. Furthermore, it has also been seen that if this protein is overexpressed in young cells, the result is great aging that accelerates. Your potential. Here the scientific team has seen that AP2A1 is not only emerging as a great marker that measures a person’s aging, but also acts as a direct therapeutic target. That is why some specialized websites such as Fight Aging! already analyze how blocking AP2A1 prevents inflammatory signaling typical of senescent cells. In this way, if we manage to inhibit this protein in the future, we could develop “anti-senescence” agents capable of extending our healthy life expectancy and combating age-related diseases, such as osteoarthritis. A long way. For now, this is something that has been estimated in cellular models in a dish in a laboratory, but it still remains to be seen how it works in the human organism with all the factors that intervene on a cell that is not isolated. What is clear is that the discovery of AP2A1 is a spectacular milestone in cell biology. We have basically found the button that controls the size and youth of cells in the laboratory, but the next big challenge for science will be to find out if we can press that same button, safely, inside the human body. And for that, there are still many years of research left. Images | National Cancer Institute Huy Phan In Xataka | While half the world is worried about aging, one industry is rubbing its hands: the elevator industry

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