Offering the cheapest gasoline in Spain has become an obsession. And 2026 is going to be the year of the great battle

The cheapest gasoline in Spain today, January 7, is found at a Ballenoil service station in Coslada (Madrid) at a price of 1,239 euros/liter, according to dieselgasolina.coma portal that monitors the price of service stations throughout our country. The second position is also from a Ballenoil service station and is also in Coslada. And the third. And the fourth and the fifth. Oh. And also the seventh, the eighth and the tenth. And the company low cost has started a war to be the company that sells us fuel the cheapest in our country. It wants to continue expanding. And along the way it will face Plenergy, another of the queens of cheap gasoline. Both have undertaken strong expansion. The cheap gasoline war Ballenoil, which is part of Cepsa moeve since just over two yearsis the leg that its parent company has to continue attracting customers who prioritize the price of gasoline above any other incentive. The company goes through a transformation campaignmaking greater efforts for sustainable fuels and electricity. With Ballenoil, Moeve has some safety net. Its service stations require very little expense because, precisely, that is the secret of gasoline low cost. Minimum investments in the stations, forget about additives and any other additional service so that word of mouth is the true driver of service stations. Low prices but good performance at volume. The strategy is working. They point out in Five Days that Ballenoil sold 1.385 million liters of fuel in 2024 and that the target figure for 2026 is 1.8 billion liters. To do this, they seek to consolidate at the end of the year an offer of 500 gas stations spread throughout Spain. Last November they were the first low cost to reach 350 stations of service in Spain. The investment is by no means exceptional. Plenergy is another of the kings of low cost with a turnover of 1,550 million euros in sales in 2024. Right now, it has 352 gas stations on the Peninsula, of which 10 are in Portugal and the rest in Spain. The objective is the same as that of Ballenoil: 500 service stations by the end of 2026. He growth of this type of business It is so high that if the plans are fulfilled we will be seeing one opening of this type of company every four days. That is, every two weeks there should be three new service stations and another on the way. And to certify it, the objective of Plenergy, they point out in Five Days is to have a 10% market share in our country. That would place it as the third most used company, only behind Repsol and Moeve. To these two giants we must add the third in contention. Petroprix, which shares with Ballenoil the service stations with the cheapest fuel in Spain according to dieselgasolina.com, also plans an expansion. For now, talk about extend your influence abroad But it also does not turn its back on Spain and talks about having 400 service stations ready in our country by 2027. gasoline low cost proves to be a huge business in our country. As we counted on Xatakaits competitive advantage is zero investment in marketing or additives. The fuel arrives at these service stations as it is distributed by Exolum, former CHLin charge of distributing all gasoline throughout our country. In return, the business model proposes sales that are large enough to compensate for the narrow profit margin, without an alternative for additional services such as large gas stations such as Repsol or Moeve receive. Photo | Ballenoil and Plenergy In Xataka | Look at gasoline and diesel to improve the electric motor. This project is committed to an untested solution

It’s about how Asia is winning the cultural battle

When I went to China for the first time in November 2023 with other colleagues, one of my travel companions wanted to take advantage of the few free hours we had to buy a Labubu to give to his daughter. I had no idea what he was talking about. He explained it to me and I stayed the same. A couple of years later, the Labubu are such a mainstream phenomenon that POP MART has opened its first store on Gran Vía and They even appear in ‘South Park’, one of the reference adult series in the West of the last 30 years (with permission from The Simpsons). The opening of a POP MART on the most iconic street in Spain, where theaters, popular fashion brands and franchises gather (special mention deserves Uniqlo and Miniso), is just the tip of the iceberg of something: the East is no longer just the factory of the world (with China as a prominent head), its weight has transcended from the industrial to the cultural to sneak into the mainstream of the West. It is a true victory for Asian pop culture, until now concentrated in its own borders with few exceptions that transcended the niche to the popular. The attractive lottery of the closed box. Of David Beckham to Rihanna passing through Dua Lipa either Lisa from Blackpink: They all have their Labubu. Born in 2015 by Hong Kong artist Kasing Lung for his illustrated book series “The Monsters”, the Labubu they exploded when POP MART started releasing them as collectibles in surprise boxes back in 2019. What started as something niche has become a trend that knows no boundaries or classes. They have them to the Thai royal house and when there is stock, it flies: fans crowd at the door in such a way that you don’t know if they are queuing to buy a ticket for a concert or if there is a rare edition. And she can be a millionaire: the human-sized, mint green Labubu has been auctioned for 230,000 Australian dollars. The Labubu as an expression of identity, status and belonging. You don’t know which one you’re going to get until you open them like it’s the reward mechanism in a video game. Of course, Labubu is not just for boys and girls. It reflects changes in consumer culture reaching millennial and generation Z adults thanks to collecting, nostalgia and the need for comfort. You buy more than a doll: it is an experience full of emotion, the status that comes with having the most exclusive edition and of course, the profitability of resale. It is the almost ideal intersection between gaming and finance: a supply and demand market where assets are stuffed. And little joke with this: POP MART has had to suspend sales in cities like london due to fights between fans and the counterfeit market It is already a reality. Whether you see it as a toy or a fashion accessory, what is clear is that Labubu has emerged as the spearhead of the soft power Chinese. China no longer (only) manufactures products, it also manufactures desire A lot of muscle, a little soft power. China is the second largest economy in the world, but in cultural influence it is quite a few steps below. The Asian giant has a legendary cultural heritage of more than 5,000 years, but for the West it is limited to silk or tea. Naming a movie or a movie star comes down to Bruce Lee (American-Hong Kong born in San Francisco). The reasons? Many and varied: from following content guidelines from the Chinese Government and censorship, but also from considering it as lower quality from a prejudiced perception. China is no longer exotic, it’s cool. First it was economically, but China is also opening up culturally to Western markets, more products appear on social networks and Western audiovisuals and the West is welcoming them with open arms. China had started promoting its brands, the New Silk Road wave visa-free entry for tourism, but nothing as effective as an innocent stuffed animal that has transcended thanks to fans, TikTok and celebrities. At a time (actually, it almost doesn’t matter when you read this) when the global perception of China is often shaped by geopolitics and surveillance, Labubu offers something different, adorable, creative and exciting. And they are not alone: ​​the game’Black Myth: Wukong‘ was a global hit in 2024 and more of the same for the ice cream and bubble tea chain Mixueto cite a couple of examples. It may end up being another fad, but right now they are objects of aspiration and desire. It is proof that Chinese cultural products can do it. That POP MART stores are in the most central streets of large cities is another way to demonstrate this. It has taken Labubu a decade to get here, China will probably have a harder time creating a solid narrative around its cultural products such as Nintendo and its Mario universe. But it’s on its way. China begins to look closely at Japan and Korea. The country of the rising sun is famous for its exports of anime, fashion and gastronomy and since 2010 it has in its strategy “Cool Japan“a government strategy to promote its creative industries abroad. However, this initiative has had its ups and downsthe weight of the market and fans in hits like Pokémon or ramen being undoubted. South Korea has what is probably Asia’s latest and most effective softpower model. With strong support from the state, the Korean wave has achieved great successes from the film ‘Parasites’ to the K-pop phenomenon. China with Labubu is another third way, with a commercial ecosystem focused on intellectual property, lifestyle and trends. In Xataka | There are people burning their Labubus in nets. The reason: a crazy theory that links them to a Mesopotamian devil In Xataka | The Labubu’s half-humanity bags are becoming too small. So its creator already knows how to … Read more

Spain wants its own public Hugging Face. The problem is that he is late to a battle that already has winners.

The Spanish Government has announced the creation of the Open Source AI Community, a platform that aspires to become the meeting point of the Spanish AI ecosystem. The initiative, presented by the Secretary of State for Digitalization and AI, María González Veracruz, is supported by ALIA and promises to democratize access to AI through open models, datasets and integration tools. Yes, but. He timing It is everything in technology, and Spain arrives when the game is already played: Hugging Face centralizes the development of open models at a global level. GitHub hosts the most important repositories. Flame Meta has become the de facto standard for many developers. Creating a national alternative now is like launching a social network in 2025: technically possible, strategically debatable. Between the lines. The official rhetoric speaks of technological sovereignty and preventing “the digital future from being in the hands of a few.” It is a legitimate argument that works in China, where the State has resources to build parallel ecosystems and close digital borders. But Spain, for good and bad, is not China. Open source AI is, by definition, global and collaborative. Fragmenting it into national initiatives contradicts its very nature. The contrast. The press release sent by the Ministry lists three objectives: Promote practical solutions. Channel Spanish leadership. And create a talent pool. The remaining question is simpler: who is going to choose ALIA when Call 4, Mistral either qwen Are they already integrated into thousands of projects? Not only is the community late, it must compete against models that already have traction, complete documentation, and active communities of millions of developers. What is also missing are concrete resources. The announcement is full of conditional promises: “putting public computing capabilities will be explored,” “there will be” hackathons“sessions will be promoted” networking. What is conspicuous by their absence are specific budget commitments, operational infrastructure from day one, or use cases that demonstrate advantages over what already exists. The big question. If Spain does not have the muscle to create viable alternatives to the American or Chinese technology giants, does it make sense to spend resources pretending that it does? Technological sovereignty is a desirable strategic objective, but it requires sustained investment over decades, not announcements with future tense verbs. The history of European technology is full of failed attempts to replicate other people’s successes without the necessary scale or capital. In Xataka | In Europe we have a problem: we are becoming the Japan of the 21st century Featured image | Secretary of State for Digitalization and Artificial Intelligence

The absurd legal battle between Elon Musk and the game “Cards Against Humanity” has ended in a bittersweet ending

The creators of the irreverent card game Cards Against Humanity have reached an out-of-court settlement with SpaceX, ending a legal dispute financed by his own fans. Although they promised to distribute the 15 million dollars they would receive from the company if they won the trial, there will be no trial to hold No money to distribute. The origin of the dispute. The story begins in 2017. Cards Against Humanity raised $2.25 million from its fans to buy land in cameron countyTexas. The goal? Legally block the construction of the wall promoted by Donald Trump on the border with Mexico. The purchase of the plot was possible, in addition to the ingenious marketing campaign, thanks to 150,000 donations of $15 each. The problem arose when SpaceX, which has the Starbase launch complex right next door, began using the empty Cards Against Humanity plot to store material. Elon Musk against the card game. In 2024, Cards Against Humanity accused SpaceX of invade your property for at least six months. In addition to starting a new marketing campaign, this time against Elon Musk, the owners of the game sued the company for depositing construction materials, gravel and debris on their plot without permission. Amid insults against Musk, whom they called “a billionaire even richer and more racist than Trump,” Cards Against Humanity promised $100 for each of the 150,000 crowdfunding participants. As? Demanding $15 million from SpaceX as compensation for the crime. Bittersweet ending. Finally, Cards Against Humanity has informed its fans that there will be no trial. SpaceX and the card game have reached an out-of-court agreement whose figure has not been revealed, but which the creators of the game describe like “Musk did the legal equivalent of throwing dust in our eyes and kicking us in the balls.” So why have they accepted it? Cards Against Humanity explained that a trial “would have cost more than we probably would have earned from SpaceX.” “According to Texas law,” they add“we probably wouldn’t have been able to recover our legal costs. We had the truth on our side, but Musk and SpaceX could have easily outspent us.” How will they compensate the fans? This is where the story takes a Cards Against Humanity turn. The 150,000 donors who helped buy the land will not receive cash, but only “comedy.” The company will send all entrants “a new, exclusive mini-pack of cards about Elon Musk,” which they hope to ship in early 2026. In an email to fans, the company summed it up: “Since we can’t give you what you really wanted—cash from Elon Musk—we’re going to make it up to you…with comedy!” The land is empty again. Images | Ministry of Communications of Brazil, Mercado Libre In Xataka | A genius named Tom Mueller designed the engines for the Falcon 9. And now that genius wants to beat SpaceX on its own turf

In the midst of the battle between Ryanair and Aena, there is a Spanish airport that is suffering more than any other: Valladolid

Villanubla airport has lost 60.7% of its passengers so far in 2025, accumulating only 59,689 travelers between January and September. The figure contrasts greatly with the rest of the airports in Castilla y León, which are growing at double digits, and makes the Valladolid airport the great victim of the fight between the Irish airline and Aena. The trigger of the crisis. Ryanair left Valladolid on March 28 after accuse Aena of applying “excessive rates”. The Irish airline, which had been the main operator of the airport, confirmed in September that I wouldn’t return either during the winter season. Without their presence, the airport has been practically disconnected: in September it transported only 6,037 passengers, 58.5% less than the same month in 2024. A solo drama. While Villanubla collapses, the other three airports in the community they rise strongly. León increases its passengers by 18.6% to 56,925, Salamanca grows by 17.5% to 21,736 and even Burgos, with only 2,413 travelers, achieves a modest increase of 1.4%. The Valladolid airport, which depended largely on the influx of Ryanair, has seen how the fight between this airline and the airport manager has taken a toll on its usual traffic, unlike the rest of the provinces in the community. What’s behind. The conflict between Ryanair and Aena has been going on for years. The Irish company has been around for a long time eliminating seats in many regional airports as a lever to negotiate discounts on airport taxes. Aena, for its part, has maintained a firm position in its pricing policy, also aware that giving in to pressure from Ryanair would set a precedent that would not suit the rest of the airlines. Valladolid has been caught in the middle of this battle. The cascading impact. The 60.7% drop in passengers not only affects the airport, but also hits the entire provincial economy. Fewer travelers means fewer connections for local businesses, less tourism and a greater perception of isolation. The 4,647 operations registered until September represent a 14.1% less than in 2024which means that other airlines have not covered the gap left by Ryanair as has happened at other airports. The only escape route. He return of Vueling This same month of October could mark a turning point, especially taking into account the seven months of operational drought at the airport. However, it remains to be seen if its offer of routes and frequencies will be enough to reverse the collapse. Cover image | Lucas da Costa e Silva In Xataka | Using the WiFi on the train in Spain is the worst. The question is why there is so much difference compared to the rest of Europe

the Vivo X300 Pro inaugurates the biggest photographic battle in recent years

China plays in another league. And the new Vivo X300 Pro has just demonstrated that the might of the Chinese mobile industry is far ahead of the competition when it sets its mind to it. with the previous generation we already checked that Vivo is consolidating itself as a total reference in mobile photography. With their new flagship just presented, they have just hit the table again. Let Apple, Samsung and Google take note, because the distance is becoming more and more evident. We have gone to Shanghai to see the Vivo mobiles. These are our first impressions of the Vivo X300 Pro. A brutal mobile that has many numbers to become the best photography smartphone of the year. Because although at the moment it is only official in China, it is already confirmed that it will soon arrive in Spain. Very attentive to everything it offers; The super high range of this end of the year that comes from China is ready to leave behind all the models that we considered leading at a stroke. Vivo X300 Pro technical sheet Vivo X300 Pro Dimensions and weight 161.98 x 75.48 x 7.99mm Screen 6.78″ LTPO 2,800 x 1,260 px 120Hz 2,160Hz PWM Dimming HDR 10+, Dolby Vision processor MediaTek Dimensity 9500 memory 16 GB Storage 512GB Battery 6,510mAh 90W fast charging 40W wireless charging rear cameras Main: 50MP ZEISS Sony LYT-828, f/1.57, 24mm Wide angle: 50MP, JN1, f/2.0, 15mm Telephoto: 200MP, ZEISS APO, Samsung HPB, f/2.67, 3.7x optical zoom, 85mm front camera 50 MP, ZEISS; JN1, f/2.0 Operating system OriginOS 6 Android 16 Connectivity Wi-Fi 7 5G Bluetooth 6.0 NFC Others IP68 resistance USB C 3.2 Stereo speakers VS1+ V3+ image chip Ultrasonic fingerprint reader Price — Once upon a time there was a camera attached to a mobile It was the headline we chose for the Vivo X200 Pro review and I think there is no better way to describe what this series represents. In the Vivo X300 Pro, photography determines everything. We are not looking at an ultra-thin mobile. Nor does it have as striking a design as one of its direct rivals, the Xiaomi 17 Pro. On the Vivo X300 Pro, the circular rear camera module It is your identity sign. There is no rear screen or pronounced curves, but a 6.78″ flat screen, a metal body that conveys solidity and attention to detail and a more traditional aesthetic. Xiaomi decided to go for innovation this year, Vivo revolves everything around the camera and sticks to what it knows works. We are looking at a top flagship in terms of technical specifications. The Vivo X300 Pro releases the new Dimension 9500the processor with which MediaTek measures itself directly against the Snapdragon 8 Elite Gen 5. They are accompanied by 16 GB of RAM and storage that uses UFS 4.1 to achieve the best management speeds. As for the battery, it is presented with 6,510 mAh, although this figure could vary in its European version, as We have already seen what has happened on previous occasions.. Taking advantage of the launch, the new OriginOS 6the new version of its operating system based on Android 16 that will allow you to leave behind Funtouch OS and incorporates an aesthetic redesign clearly inspired by Liquid Glasshas considerably improved its fluidity and adds compatibility with PC and Mac for sending files and screen mirroring. Five years of guaranteed system updates will be offered with the Vivo X300 Pro. ZEISS puts the icing on the cake with a 200MP telephoto and a single main sensor In the triple camera of the Vivo X300 Pro, there are two sensors that stand out especially: the telephoto and the main sensor. For the wide angle we have a 50 megapixel, autofocus and 15 mm sensor, signed by ZEISS, like its entire camera. But this is not where we find the great photographic leap. It is in the main and in the telephoto where Vivo puts all the meat on the grill. The telephoto lens of the Vivo X300 Pro is a ZEISS APO sensor with 200 megapixels and 3.7x optical zoom of 85 mm. Vivo is betting on an ISOCELL HPB “Thanos” sensor with 0.56 μm pixels manufactured by Samsung for the occasion. With this addition the new phone becomes at the height of the X200 Ultra model which we had the opportunity to test a few months ago, but it is not so immediate, because Vivo promises that it is a completely new sensor. A new 200 megapixel sensor for the telephoto that promises to eclipse everything seen so far. We have had the opportunity to test it briefly during its presentation and the result in x5 and x10 is astounding. 24mm image (left) vs 2x 48mm zoom image (right) 3.5x 85mm zoom image (left) vs 10x 242mm zoom image (right) And it’s not just the components used, the aggressive AI processing achieves images with extraordinary definition. For me who comes from photography of the Google Pixelthis Vivo X300 Pro is along the same lines and I would even say, without testing it in detail, that it surpasses them. The second protagonist is the LYT-828 main sensor with 50 megapixels, 24 mm and lens with f/1.6 aperture. It is a sensor co-created between Vivo and Sony, signed by ZEISS and that promises a stabilization up to CIPA 5.5a standard on the order of those achieved by gimbals, they say from Vivo. It also has a ZEISS T* anti-reflective coating to try to reduce flare and ghosting. But the advantages of this sensor do not stop there. The LYT-828 is probably the most advanced photo sensor available in a mobile phone to date. It is about the first sensor to achieve a dynamic range of more than 100 dB and almost 17 steps. What does this mean? Mainly that images with exceptional HDR can be obtained; which translates into super vivid images with a very wide range of colors. This commitment to colors also … Read more

La 1 only had to win the morning battle. It has achieved it as with everything else: by politicizing its content

Follow the rising rhythm of RTVE. The only part of the day that remained to be conquered, with two giants of morning news at the helm such as Ana Rosa Quintana on Telecinco and Susanna Griso on Antena 3, it was in the mornings. And after a series of changes in search of an identity, finally ‘Mañaneros 360’ has found success, with a share which doubles what it had a few months ago. And along the way, he has angered the government’s political rivals. The figures. The historical audience record was achieved by ‘Mañaneros’ on Monday October 6 with a 16.9% share (also preceded by another success on the network’s mornings, Silvia Intxaurrondo and the debate on ‘La Hora de la 1’, which this season is exceeding 20% ​​on several days). Both programs are experiencing the best moment of their respective histories (‘La Hora’… is five years old, and ‘Mañaneros’ is two years old), but it is not an isolated phenomenon on public television. In general, the mornings increase in audience: ‘The Ana Rosa Program’, for example, also the season is starting very well with figures that are helping to boost Telecinco’s totals. Hesitant starts. Until reaching this point, ‘Mañaneros 360’ has undergone some changes. It started in September 2023 simply called ‘Mañaneros’ (another one was previously proposed, ‘Bienvenidos’), and with Jaime Cantizano at the helm, after more veteran options such as Jordi González, Isabel Gemio and Gemma Nierga were discarded. Cantizano accepted an assignment very inspired by the morning magazines on North American television, which sought to distance himself from the competition of Quintana and Nierga. The result was a hodgepodge of sections that mixed health, events and heart, without a fixed order to surprise the viewer every day. The casual tone was cultivated, significantly, with a heart section that already mattered to collaborators of ‘Sálvame’ such as Terelu Campos, Lydia Lozano, Chelo García Cortés and Alba Carrillo. The result was discreet, with an average of 8.2%, but improving, as reported by ‘El País’ in a chronicle of the history of the programthe figures of its predecessor, ‘Speaking clearly’, which had been closer to 7%. New changes. Cantizano ended up quitting his job because he couldn’t stand the stress: Monday to Friday on television, and Saturdays and Sundays on Onda Cero. He was replaced by Adela González, who had experience in live programs like ‘Sálvame’, and with her came an even more relaxed tone thanks to the experience of the presenter, and which increased the audience. The following change did not come from within, but from outside the program: Sergio Calderonwhich would take to port very notable changes in the RTVE grideliminated the social chronicle part (which led to a series of not very well received dismissals, as the aforementioned article comments) and introduced a political chronicle part, commanded by Javier Ruiz. Enter Javier Ruiz. Ruiz, who in addition to presenting and directs the program, has given the program a definitive boost in audiences, focusing almost its entire duration on current politics and turning it to the left. Whether the openly progressive positioning of the program is debatable or not (the eternal discussion of the politicization of public television), it is clear that this is what is providing audiences. And many of the most apolitical sections ended up migrating towards the evening ‘Sálvame’ project, ‘The TV family‘, which ended up shipwrecked. Chainsaw or flamethrower. This is how VOX said that it would enter RTVE when it had the support of the voters, in the mouth of his deputy Manuel Mariscal. He made reference to the leftist speech of Marc Giró, Jesús Cintora, and also Javier Ruiz. Without a doubt, (literally) incendiary words for a change in programming that is bothering conservative sectors (there was also the root of the Mariló Montero’s loud anger on David Broncano’s program). But, somehow, it is getting more audiences than ever. In Xataka | Thirty years later, there is still an unbeatable television format in Spain: desktop soap operas

In his battle for being the best back pain medicine, ibuprofen has just found a serious competitor: cannabis

Lumbar pain is something that can be very common in society by the clinic so annoying that it has associated as the problems getting up from a chair, to walk or even to bend down. This makes research focused on seeking a treatment for this type problem that exceeds anti -inflammatory and analgesic classics. AND The key may be precisely in cannabis. A study. Recently published, an investigation whose results have been published in Nature Medicine, He has shown that a cannabis extract can reduce chronic low back pain. The drug called Ver-01 not only calms pain, but also Improves sleep and physical function. But the most important of all is that it does not create any dependence or withdrawal syndrome, so it is an interesting option to opioid analgesics such as the Tramadol. The problem. Chronic low back pain is one of the main causes of disability worldwide, By affecting more than 600 million people approximately. Those who suffer from Manudo faces a dead end in the therapeutic field by not having a healing path beyond taking NSAIDs and trying to reinforce the muscles in the gym. But the big problem is in the most powerful analgesics offered when ibuprofen does not finish working, but that creates a big dependence problem in our society. What is it. Obviously, we are not talking about smoking cannabis. Ver-01 is a highly standardized pharmaceutical product that is an ‘complete spectrum extract’ obtained from a patented strain of Cannabis sativa called DKJ127. But … What does ‘complete spectrum’ mean? With this term we refer to that in addition to its main psychoactive component, the THC, the extract contains a complex mixture and characterized by other compounds of the plant like others Cannabinoids (Cannabigerol or Cannabidiol), Terpenos and flavonoids. This integral composition could be key in its efficacy and tolerability profile. Methodology. There is a lot of fear around the ‘cannabis’ and the use that can be given because it logically He has long highlighted all the harmful effects that can have its consumption prolonged over time. But given the need to find a therapeutic alternative, a team of researchers evaluated the effectiveness of VER-01 in a phase 3 clinical trial. That is, the last stage before approved a medicine for commercialization. To do this, a Multicentric studyrandomized and placebo controlled. That is, a group of 820 patients with this pathology were divided into two groups and in this way for 12 weeks 394 participants received VER-01, while 426 received an identical placebo in appearance and flavor. Results. The study fulfilled the objective that had marked from the beginning. Patients who took VER -01 experienced an average pain reduction of -1.9 points on a scale from 0 to 10 on the NIR scale (numeric pain scale). On the other hand, for the placebo group there was also an improvement, but less accused of -1.4 points at the level of pain. The question is … Has it been for the drug? Our “great friend” statistics tell us that it is a statistically significant result. And although the figure may seem modest, in the treatment of chronic pain these levels of improvement are that they are very relevant. In fact, the effects were even more pronounced in patients with severe pain and in those with a neuropathic pain component (caused by nerve damage) and which today is about all with gabapentin. Benefits. In addition to the improvement in pain levels, there has also been an important improvement in the dream. Patients who received VER-01 as a treatment saw that the quality of sleep and their ability to do daily physical activity improved a lot. This is crucial, because they are classically the two aspects most affected by low back pain. He does not stay here, since it was also determined that patients had a less need to resort to rescue medication compared to the placebo group. Something that also points us to the effect is more elongated. Sure. One of the most important aspects when designing a new drug is that it is safe and can be tolerated. VER-01 treatment was well tolerated, and what is relevant is that no sign of abuse, dependence or symptoms of abstinence was detected, even after a sharp interruption of treatment. Although it is not 100% safe, because as any medicine can have adverse effects. The positive thing is that the vast majority were mild to moderate and transitory intensity. The most common were dizziness, fatigue, nausea and dry mouth. A hope. This study is one of the most rigorous to date on a medication based on cannabis for chronic pain. Its results show that Ver-01 not only provides a reduction means of pain, but also addresses other problems that are associated. By offering an effective therapeutic option, safe for long-term use and without the ghost of addiction, VER-01 is emerging as a fundamental tool in the future of pain management. It still remains for the market to need to have the final approval of the FDA and subsequently its arrival to the rest of the markets, provided that the new comparative studies with other opioids are satisfactory. And it is that putting an investigation date is certainly very daring, but this treatment is closer than we think. Images | Rick Proctor Sasun Boughdayan In Xataka | There are so many people growing marijuana in their homes that Endesa has a problem. And it will solve it with ia

A very rare element of the periodic table is unleashing a new geopolitical battle with China: Germanio

China has been weaving, little by little, a network of power around critical minerals: first Rare earthsafter Copper And now Germanio. Although its name barely says anything to the general public, this metal is essential for the defense industry – from the night vision systems of the fighters to the satellites – and for the optical fibers that support the Internet. Today there is almost no market, its price has been quintupled in two years and the origin of the collapse has a clear name: Beijing. The origin of the crisis. Two years ago, China announced controls At the exit of Germanio, Gallium and Antimony in response to the restrictions of the United States and the Netherlands on advanced semiconductors. However, the real blow arrived at the end of 2024: Germanio’s exports collapsed, leaving merchants without supply. Terence Bell, from Strategic Metal Investments, I recognized Financial Times That had been able to buy a gram six months. “The situation is desperate,” he said. Aaron Jerome, from Lipmann Walton & Co, described a devastated market: “Before we could buy 100 kilos; now we are lucky if we got 10, and the triple price.” And Christian Hell, from the Tradition Commercial House, added to the same medium that the demand was “for the clouds” and that he received desperate consultations of companies from the United States and Europe. The figures confirm the collapse. According to a Policy Accelator Silverado analysis cited by Financial Timesbetween January and July of this year, Germanio imports to the United States from China fell 40%. The result has been an unprecedented price escalation: just $ 1,000 in 2023 to almost $ 5,000 in September this year. This is the highest level registered since 2011. A strategic role. The importance of Germanio is not in its geological rarity, but that it is very difficult to extract, since it is obtained as a zinc and coal byproduct. In addition, its use in defense is irreplaceable for thermal image systems in fighters, drones and satellites. In the civil sector, it is used in optical fiber, solar panels and chips. “Finding substitute materials is complicated, because it would imply a complete redesign and a loss of unacceptable precision in military applications,” explained the analyst Caroline Messecar in Financial Times. For these reasons, According to estimates from the Fastmarkets agencyworld demand is around 180-200 tons per year of Germanio. One more piece of a much wider board. In Beijing they have converted critical minerals into geopolitical weapons. At the end of 2024, They prohibited export from Gallium, Antimony and Germanio to the United States, and shortly after added Scandio and Disposioessential in chips, telecommunications and storage. The strategy behind the Asian giant is to monopolize the control of the entire chain. To name a few examples, China has 4% of world copper reserves, but controls 49% of the global refining. “More than accumulating raw materials, China is building an intentional bottleneck in the supply chain,” My partner has detailed in Xataka. The same goes for the Tungsten, where it controls 83% of the world supply and tightened the export controls in February 2025, What fired prices 55%. In simple words: Beijing seeks to be essential. It controls the most valuable link – the defendant – and with it conditions global access to strategic metals of the 21st century. However, its power is not absolute: it depends on importing concentrates from countries such as Chile, Peru or Mexico. If any of those partners change position – Mexico, for example, 50% tariffs have already imposed Chinese products in 2025-, Beijing risks a cut of vital supplies. In addition, this control strategy has a price: Chinese copper foundations work with negative margins and some have had to close. A movement to counterreloj. Before the blockade, Germanio’s great consumers try to move quickly. On the one hand, in the United States, defense giant Larkheed Martin signed in August a direct agreement with the South Korea Zinc to ensure supply, something unpublished so far. Lightpath Technologies, with government support, works in optical alternatives, although its director Sam Rubin warns in ft: “No one is going to redesign an existing system until it is inevitable.” On the other hand, the options are scarce. Umicore in Belgium and Teck Resources in Canada produce some Germanio, but insufficient. Germany He already warns thatif the crisis lasts, its automotive industry could stop part of the production in a matter of weeks. The European Chamber of Commerce has even asked Beijin to release supplies for chips factories. The historical supplier, Russia, has also been out of the board. For years it was one of Germanio’s main sources for the West, thanks to its production associated with zinc and coal mining. However, international sanctions for the Ukraine War cut that flow almost completely. Moscow continues to produce, but its exports are now directed to China and countries that do not participate in the sanctions, According to FT. For the United States and Europe, that means having lost another supply route in the worst possible time, which has further reinforced Beijing’s domain. Looking to the future. In Germany, a group of researchers from the Technical University of Freiberg Work in a method surprising: extract Germanio from plants after fermentation processes for biogas. At the moment, they only achieve some milligrams per liter, but they aspire to reach a gram, which would open the door to a sustainable and local production. From anonymity to key element. Germanio has become a symbol of a new era: that of minerals as strategic weapons. As Financial Times has pointed outdemand does not stop growing while the offer narrows. And the lesson is clear: in an electrified and militarized world, who controls critical minerals will control power. Image | Freepik and Unspash Xataka | Nickel’s paradox: West needs it more than ever for electrification, but China and Indonesia have market dominance

Casio knows that his calculators have the lost battle in the West. So you have designed a B: Africa

In a world dominated by smartphones, where any mobile has a calculator application, it might seem that the days of pocket calculators are counted. However, Casio, the Japanese giant who has been in the business for almost 60 years, has a plan to stay as a relevant company: carry its scientific calculators to the classrooms of developing countries. In search of the ideal countries to continue expanding. Since its first scientific calculator in 1972 was launched, Casio has achieved great achievements such as a reference in the Spanish Meracdo. But now he focuses on eight countries in Asia and Africa, among which are Egypt, Thailand, Indonesia, Bangladés and the Philippines. The calculator as an infallible ‘antitrampas’ system. The program baptized as ‘Gakuhan’ is not limited to selling calculators only. Casio seeks to promote teaching methods that integrate these devices, pressing so that schools use them in classes and allow their use in exams. The reason is simple: the calculators They have a much less copy risk than smartphoneslacking Internet connection functions. In the case of Spain this is something that we see in the selectivity, for example, where one of the requirements is obviously not having any electronic device on top and Nor any calculator that can transmit information. Although always when you get to Baccalaureate, it is raised The question of which is the best calculator to study. And this is precisely what they sell to the professors of Asia and Africa with a sales manager who has become the official ambassador of this program. The objective of its task is clear: create educational material where the calculator is essential to develop the activity and offer competencies to students. A market in decline, but with a resilient niche. Despite the presence of smartphones, Casio has managed to maintain a stable business with calculators. Although the sales of this device have fallen two thirds from its peak in the last 20 years, the company sold more scientific calculators than basic last year. In fact, it has expanded its range of scientific calculators to 73 models, 40% more than seven years ago, to adapt to the subtle differences of each country. European countries have their ‘antitrampra’ versions. For example, in Germany and France Comas are used instead of points for decimals and the graphic calculators of the United Kingdom They have an “exam mode” that deactivates the functions not allowed. Although the educational technology business of Casio is not as large as that of watches, which generates 60% of total salesit does provide a constant income flow. The company expects Sell 23 million scientific calculators in 202510% more than the previous year. Other products have not had the same fate as calculators. Mobile phones have caused the disappearance of many products or even icons that we had normalized in our society, such as public phones, Pocket cameras or the music players like the walkman either The iPod. In this case they have failed to reinvent themselves to continue advancing with the new advances of society. Others, such as instantaneous cameras, They still have their niche Within lovers of Vintage, Like what happens with vinyl. But in this case the calculators in mobiles, tablets or computers do not seem to end the products dedicated to it. In institutes it remains a practically mandatory product and on which we depend on not making the calculations with a pen and paper such as a simple division. Images | Robert Schneider Aaron Lefler Doug Linstedt In Xataka | Better scientific calculators: which to buy for the institute and the university and eight recommended models from 10 euros

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