“Cozy games” were going to save us from stress and productivity. They have ended up being true slaves of leisure

The promise of relaxing and clearing your mind for a few hours is what attracts us of the cozy games: those games that surround us with cute little animals, calm us with a comforting visual palette and give us repetitive and friendly tasks that make us escape from stress. It all seems very bucolic; You inherit a farm, plant flowers, decorate rooms or make dream furniture, with the promise of escaping for a few hours from the daily routine. However, that kind of digital refuge has become the materialization of what you wanted to escape from; in a second Google Calendar full of meetings, in a clone of your 9 to 5 job. And ‘Tiny Bookshop’ reaffirms it to us. Released this summer,’Tiny Bookshop‘ quickly became a hit within the crowded category cozy. The premise is clear: you arrive in a small, charming town with your new traveling bookstore project, which you can decorate with hundreds of possibilities. Through your relationship with the neighbors you manage to sell and recommend a large number of books and, in turn, discover all the secrets of the town. This entire initial point is more than striking for fans of the genre (like yours truly). After more hours than I would like to admit, I realized that I had fallen into the gaming trap again. cozy: dedicate hours and hours at a job. Underneath the adorableness of being able to paint everything in pastel tones or recommend ‘Jane Eyre’ to your clients, in the end you find that you have been searching for objects for a while to increase your sales, check the opening hours for the next day and be on the lookout to replenish the shelves with the right genre. You can call this cozybut I call it emulating another workday; and what’s worse, enjoying it. Recommend all kinds of books at ‘Tiny Bookshop’ At the beginning of the 2010s it became quite fashionable, sponsored by the gurus of Silicon Valleya trend called “gamification of work“Through video game or board game mechanics, missions, points or rewards were added within the daily routine of monotonous work tasks. It is worth asking if the cozy games They have done the opposite path, “trafficking” video games. It is true that, as is often the case with these cozy gamesit’s easy to have fun with them and immerse yourself fully in the story. The interactions are adorable, the characters are cute and they have that air of “afternoon movie” that makes them irresistible; but in the end we cannot ignore the fact that we are replicating tasks that we are supposed to escape from, such as spending hours and hours working. And yes, it all depends on the type of player you are and how you manage the objectives of the game, but the cozy games They rarely have to do with something comfortable or warm. We’ve romanticized even paying a mortgage We are not talking about a specific thing that happens with this new release, completing or performing the daily tasks of this style of games can be the least relaxing thing there is. With the pinnacle of the cozy‘stardew valley‘, the day doesn’t last long between milking the cows, collecting the eggs, making jam and going to the mine to get objects. Furthermore, as if it were real life itself, after all these tasks, you have to put on a good face and interact with your neighbors. Something similar happens with another of the big names in the category such as ‘Animal Crossing‘: you have to give objects to your island companions, cut down trees, plant flowers, fish and be attentive to the day the character who is in charge of buying your collection arrives, in order to get money and pay the mortgage. Yes, a mortgage on a beautiful house, but Tom Nook does not forgive the deadlines. After all this, it would be interesting to check the players’ heart rate when their character goes to sleep after completing all those tasks. Spend the day cutting down trees in ‘Animal Crossing’ By becoming something more mainstream and produce some sales more than substantial Since its rise in the pandemic, there are countless games that adopt the “cozy” to capture the public, even when its dynamics move away from what characterizes the genre. It is worth asking if within this label, the greatest exponents should not be games like ‘Abzu‘ either ‘Unpacking‘, where the “you don’t have to do anything” is strictly followed and the objectives do not have a timer. The contemplative and the mechanical is what is essential in these examples, honoring that part “cozy” of mental refuge with peace, serenity and tasks that are repeated over and over again. In fact, there is even metacriticism within this world. ‘Wanderstop‘, a tea shop simulator created by the visionary mind behind ‘The Stanley Parable‘, Davey Wreden. The game ironizes this fact with a character who invites you to attend to customer requests when it seems right to you, without rushing, because the last thing the protagonist needs is it’s more pressure. It is curious that most games cozy They deal with mental health or anxiety, but some have mechanics in line with this and others offer ones that are radically opposite to the feelings they seek to create in the player. The perversion of language, or the excessive use of a label such as “cozy” to sell more copies ends up producing a very specific reality: something is broken when the first thing that comes to mind when we talk about these comforting games is taking care of a farm or a supermarket, watering parsnips or paying for an extension to your house. Productivity as leisure Beyond the mechanics and quality of each of them, the addiction and fanaticism that they generate for us does nothing more than put ourselves in front of the mirror and expose the reality of our daily life: even with our leisure we want to be productive, … Read more

The housing market is so broken that it has found an unexpected channel for express purchases: Telegram

The housing market is overheated. It comes with taking a look at your price curvehe residential deficit calculated by the sector, the accelerated tempos of the agencies or simply the conditions (increasingly draconian) that real estate agencies require from tenants looking for an apartment to confirm it. There is another place however where that fever is clearly perceivedone that has little to do with agencies, portals like Idealista or the offices of the promoters: Telegram. There it is increasingly easier to find apartment purchases that are closed in minutes with a clear investment focus. Seen and unseen. The news I advanced it a few days ago The Country. If there were doubts about the imbalance between supply and demand in the Spanish real estate market or to what extent housing is awakening the appetite of investors comes with taking a look at Telegram. In the same messaging app that many of us use to talk to our families or friends, there are groups with thousands of subscribers that have become real real estate showcases. Of course, with certain peculiarities: speed prevails in the channels, the ‘seen and unseen’, with a clearly investor focus. It is not unusual for sales to be settled in a matter of minutes, sometimes by buyers who do not even get to visit the home they are purchasing in person. At the end of the day, you are not looking for a home. Generally, those who buy do so attracted by the promise of high returns. And one of the most popular ways is the rental market. How do they work? The mechanism is quite simple. The channels are run by specialized companies that are previously in charge of tracking the market in search of assets with potential, apartments in locations with rising markets, at reasonable prices and in which it is possible to charge tenants monthly payments that, over time, will translate into profitability of the 6%, 8%, 9% or even 13%, far above than other more conventional investments offer. Once the company ‘hunts’ that real estate asset, it offers it on its Telegram channel with a series of key data: area, location, age, sale price, estimated rent and profitability forecasts. Potential buyers send emails showing their interest and then the company chooses among the candidates, either by lottery or following the order in which they have written. It is not unusual for the buyer to never see the property or even live in another city. At the end of the day, what counts is the promise of economic return. How frequent is it? Last year the General Council of Notaries registered almost 716,200 home sales in Spain. Among this enormous volume of operations, those closed expressly through Telegram could have represented a small part (there is no official data), but even so the phenomenon is interesting enough that it has followers. The Country speaks from several companies that launch offers every week through groups in which they reach 3,000, 10,500 or even 15,000 subscribers. Specifically, he cites three companies in the sector: Winteromics, Nexiaprop and Buy 1 apartmentalthough not all of them are the same nor do they use Telegram with the same frequency. More than just speed. That the formula is arousing interest is explained by the characteristics of the real estate market. In cities with very stressed markets, such as Madrid, Barcelona either Valenciarents rise, but so do (and not a little) the price of properties, so its real estate stock loses interest for local investors in search of available homes to direct them to the rental market. Solution? Look beyond the metropolises, in other locations, if possible in municipalities where prices are still reasonable, where population is gaining or an increase in demand is expected in the near future, for example due to the arrival of a multinational. Hence, buyers are interested in homes that may be hundreds or thousands of kilometers from where they live. Mediation companies not only promise huge financial returns. Sometimes, if the expected returns are not achieved, they undertake to cover the difference or even offer their services as intermediaries to take care of the renovations or rental management. That is, even if the investor has in mind becoming a landlord, he or she will not even have to act as such. The company itself takes care of it… after payment (of course) of a commission. Looking for strategic areas. The focus is usually on homes located in working-class areas, without conflicts, with sales prices that usually do not reach or range around 100,000 euros. Companies also manage to ensure that these properties are not even offered on the open market, thus becoming the first to hunt for ‘bargains’ for investors. The companies they allege who with their work increase the rental supply and unlock properties that have been empty for some time. Of course, it’s not all advantages. As in any investment, the sector also recognizes that there are “risks”, especially for buyers who purchase apartments without first seeing them in situ. Images | Ivan Radic (Flickr) and Kaspar Upmanis (Unsplash) In Xataka | For years, motorhomes were a luxury. Now they are something else: the last stronghold against the housing crisis

science has a different opinion

For a person with celiac diseasesocial life can be a real minefield. Cross contamination is a dangerous enemy that is present in the way food is prepared, but also in the kisses we have with other people. In this way, the question is obligatory: if my partner has eaten bread, pizza or pasta… Is it dangerous for us to kiss if I am celiac? To answer, luckily we have science on our side. Until now, people who have to stay away from gluten for serious medical reasons could be afraid to kiss if their partner had not rinsed their mouth or brushed their teeth before. But science is pretty transparent. in the preliminary study presented at Digestive Disease Week 2025. Their conclusion is quite clear: some gluten can be passed through a kiss between two people, but the amount is so small that it is very unlikely to have relevant clinical consequences. The study. To reach this conclusion, 20 non-celiac people who ate a food with a large amount of gluten were recruited. Immediately afterwards, they had to kiss their celiac partners, allowing the researchers to measure the concentration of gluten in the saliva that had passed from one boba to another. The results were quite clear: in 18 of the 20 couples, the levels in the recipient’s saliva were below the international “safe” threshold, which is 20 mg, and furthermore, none reported symptoms related to intolerance. Although if you drink a little water before kissing, this risk decreases even more. Why 20 mg. This threshold value is not something random, but rather it turns out to be defined by science itself. Here one of the reference studies comes into play, Catassi’s essay and collaborators published in American Journal of Clinical Nutritionwhich administered 10 or 50 mg of gluten daily to adults with treated celiac disease for 90 days. What was seen is that the daily exposure was clearly below that 10 mg range for the majority of patients. A later review in Alimentary Pharmacology & Therapeutics reached similar conclusions: the doses that are beginning to be worrying move in the order of tens of milligrams per day, especially if they are maintained over time, not in single isolated traces. In this way, an isolated kiss has the same concentration of gluten as foods that are categorized as safe. How is it possible that a kiss after eating a large amount of gluten-containing foods is not dangerous? This is the question we ask ourselves after reading these conclusions, and it has an answer, but in studies done on peanutsanother allergen. In this case it was seen that just after eating, the concentration of allergen in the mouth is really high. But after simple measures such as waiting a few minutes, drinking water or brushing your teeth, levels drop drastically. In this way, a kiss does not transfer food, but rather a fraction of a milliliter of saliva. And that saliva, minutes after eating, has already “cleaned” most of the protein that was inside. And this is valid for all allergies that are mediated by immunoglobulin E (which is responsible for generating the allergic response). There is a margin of safety. On a daily basis, people who are intolerable to gluten and who follow a very strict diet to avoid contamination, the truth is that they consume this allergen. Although in a very small quantity. This shows it a study who developed techniques to measure gluten immunogenic peptides (GIP) in urine and feces. The work showed that many people with celiac disease who follow a strict diet have small accidental exposures on a regular basis, the result of cross-contamination in modern life. However, the majority do not show clinical worsening or intestinal damage if these exposures are spontaneous and at very low doses. A kiss, in the worst case scenario, is exactly that: an isolated microdose exposure. The final verdict. What this new study provides is not a revolution, but a reassuring quantification of something that the consensus of experts already sensed. Even the main patient associations, such as the Celiac Disease Foundation or Coeliac UK, have been with a practical message for some time: the risk of kissing is low. The only common sense recommendation, which is still valid, is to avoid kissing right at the moment when the other person is eating gluten or has obvious remains of food in their mouth. You always have to wait a little for the saliva to take effect, but it doesn’t have to be a problem beyond this. Images | Cassie Lopez Wesual Click In Xataka | The difference between celiac disease and gluten intolerance can be difficult to appreciate. But there is a key detail that makes them very different.

There are eight million Airbnbs, but only one where the disconnection is so extreme that there is fine print: risk of death

At the beginning of the year, the figure by Bryant Gingerich began to circulate in many media. In a secluded corner of the Ohio wilderness, Gingerich, a 34-year-old engineer, seemed to have found an opportunity to transform his professional life by converting a simple cave in a successful vacation rental business. However, if we talk about places far away from the world, none like the one in this story. Stay at the extreme. I told the story a few days ago BBC. In the Kulusuk Fjords of eastern Greenland, the Floating Glacier Hut It has established itself as one of the most remote accommodations, if not the most, in the world. The cabin, installed on a floating hexagonal platform and anchored to the surrounding rocks, it is located in an area where the distances between settlements are enormous and the human presence is minimal. Access is made only by boat and the infrastructure responds to the idea of ​​offering a space completely removed from any urban dynamics, in a territory dominated by glaciers, icebergs and an unpredictable climate. This approach fits with the rise of the so-called as “quietcations” and hyper-remote destinations, which seek to satisfy the growing need for total disconnection that many travelers express in the face of the accelerated pace of daily life. Disconnect without technology. The cabin dispenses with the internet and reduces outside communication to a satellite phone, which forces us to live real isolation throughout the stay. The Finnish-made module is thermally insulated and has a glass roof that allows you to observe the polar sky and phenomena such as the northern lights without leaving the interior. The equipment it’s basic: a small stove, a toilet, a minimal kitchen area and a double bed. The lack of a shower is part of the design, and some visitors resort to quick dips in the frozen sea to clean themselves. This austerity is proposed as a central feature of the experience, focused on the observation of the environment and sensory immersion without digital interference. Views from the accommodation Caution and logistics. Extreme isolation coexists with reasonable vigilance against the risks inherent to the Arctic. According to the local guide Nicco Segretoresponsible for the project, the cabin acts as an effective refuge from potentially deadly fauna like polar bears (there is a sign that warns you before entering), as long as you stay inside. However, the operator warns that weather conditions may prevent the arrival of the boat in charge of transporting guests, an element that is part of the operational reality in the region. The landscape offers opportunities for activities such as glacier hiking, exploring ice caves formed by subglacial rivers, and ice fishing through a small hole prepared in the structure. These excursions show the dynamics of ice and the visible effects of melting, reinforcing the educational value of the trip. A tourist project. Secret discovered a decade ago a glacial cave that today is part of the activity offerand that discovery was the origin of his initiative to develop low-footprint tourism in the area. In addition to generating employment in the Tasiilaq community, the project aims to attract travelers interested in geology, the behavior of ice and the magnitude of the polar landscape. The Floating Glacier Hut It is the initial phase of a broader plan that includes a future retirement of greater capacity, Vision Lodgeaimed at structured stays of several days. The accelerated retreat of the glaciers, visible even year after year, becomes a central component of the experience, which allows us to observe climate changes on a human scale. An exclusive model. The stay, designed for two people, has an approximate cost from 1,000 to 1,200 dollars per night and includes private boat transfers, dinner prepared by the guide himself, and breakfast. Despite the price, remembered the BBC that the accommodation It has received very positive reviews for the combination of isolation, landscape and silence, elements that guests point out as difficult to find in other destinations. Thus, the general perception is that it is an experience designed for those who seek to completely disconnect (from humanity and devices), observe the environment without filters and face a slower pace, where nature is the central axis of the room and the passage of time seems to acquire another scale. Image | Vision Lodge In Xataka | An engineer left his job to transform a cave into a vacation rental. He’s making a fortune a year without Airbnb In Xataka | Italy vetoes one of the great symbols of mass tourism: the use of key boxes for self-check-in is prohibited

It is essential to give us the key to leukemia

The bone marrow is undoubtedly one of the most complex, and at the same time vital, tissues in the human body. It can be said that it is the “blood factory” of the body where stem cells are born that keep us alive and that gives rise to our defenses or our red blood cells. However, studying it is a real nightmare as it is encapsulated within the bone such as the femur. Until now, scientists had to choose between study cells on a flat piece of plastic (which looks nothing like the real body) or use micewhich, spoiler: they are not human. That is why there is now a real revolution in this field, since they have managed to create a great model that will make life much easier for science. The study published in Stem Cell just changed the rules of the game. A team of researchers have managed to create eVON, a macroscale, 3D, vascularized model of the human bone marrow that not only has cells, but “breathes”, has functioning blood vessels and even nerves. Why does it matter? Although it seems insignificant, the reality is that right now there were many doubts about how they develop diseases as aggressive as leukemia. In this case, this piece of tissue engineering opens the door to finally understanding how leukemia works and how to cure it without depending so much on animal models that are not faithful to the anatomy and physiology of humans. Until now, the solution to research also involved taking a Petri dish, which is nothing more than a piece of plastic, and cultivating the stem cells here that will give rise to the components that we have in our blood. Logically, they died quickly here, since they lacked the environment where they were truly comfortable ‘living’. It is what is known as endosteal niche. This niche is the specific neighborhood within the bone where stem cells interact with blood vessels, bone, and nerves to decide whether to multiply or become white or red blood cells. Something fundamental to understand what is happening there. We already have a solution. eVON is presented as a wonderful alternative, since it has three key elements: A ‘scaffold’ composed of the same mineral that we have in bone to imitate the hard structure of the trabecular bone human. No white gelatin, but something that feels like a real bone. Stem cells that have been reprogrammed in the laboratory to generate both bone and blood tissue. Functional vascularization, thanks to the fact that they have managed to make the cells form networks of capillaries and blood vessels that penetrate the artificial bone. And the truth is that they have managed to introduce all the components that are around them into our marrow. Most surprising is the level of detail: The model spontaneously developed sympathetic nervous system nerve fibers and macrophage-like cells, creating an entire ecosystem that no one had ever had to explicitly “design” cell by cell. They have literally created a blood factory. The fight against leukemia. Acute myeloid leukemia is a cancer that is undoubtedly devastating and that often “hides” in the bones themselves, making it very resistant to chemotherapy since it is difficult for the medication to reach the bones. The good news comes when the study shows that eVON recreates the exact molecular signals that tumor cells use to survive. And this is fundamental, since attacking these genes is like hitting their weak point. In short, it gives us the necessary tools to be able to kill tumor cells and cause them to die. The test. To prove that their “artificial bone” was robust, the researchers did something worthy of science fiction: they implanted the eVON tissue under the skin of mice. And the truth is that the result was very good: the human tissue integrated with the mouse and the human blood vessels connected with those of the mouse. In this way, the human stem cells survived and were able to repopulate the mouse blood with functional human cells. But logically there are still challenges that must be overcome, such as the size of this model. To do this, it still needs to be reduced so that large-scale tests can be carried out with drugs that can kill these tumor cells. Images | ANIRUDH National Cancer Institute In Xataka | 125,000 years ago Neanderthals ate bones to survive. Today we discovered that they were right

Opera Neon promises to be the future of the browser. It is an ambitious vision yet to mature

I’ve been using it for a week Opera Neon and I don’t know if I’m testing the future of web browsing or participating in a psychological experiment on how much friction a human tolerates before returning to their usual browser. Probably both. Neon comes standard with everything that any veteran Opera user takes for granted: side messaging integrations, music apps in streamingthe multimedia panel… It is the reminder that, despite all the agentic experimentation, there is still an Opera underneath: practical, comfortable and designed for those who live glued to several platforms at the same time. The promise is seductive: a browser that not only answers questions, but act for you. Who browses, compares, reserves, creates. Who understands what you want to do and does it while you focus on more important things. Opera calls this “agentic AI“, and technically it is correct: Neon can take control of the browser, open tabs, fill out forms, compare products. It is AI with hands, it is Opera’s proposal for the same field as Perplexity with Comet or OpenAI with ChatGPT Atlas. The problem is that those hands are sometimes clumsy, unpredictable and dangerously overconfident. Opera Neon maintains all the classic features of Opera, such as the side panels to display messaging mini-applications or streaming music on an upper layer. In the image, Apple Music. Image: Xataka. Three brains in one body To understand Neon you have to accept that It is not an AI browser. It is a browser with three AIs living together. Chat, Do and Make. Each one with its function, its purpose, its personality. And here begins the first big problem: knowing which one to use at all times is a guessing exercise. Chat is the most familiar. A conversational chatbot that answers questions, summarizes pages, translates texts. Typical. It works well when you’re not making things up, which is about 70% of the time. I asked him to count the comments on several articles and he responded with 400 words explaining that there were none. when there were four. Do is where magic and terror live. You ask him to book a CrossFit class, find the cheapest flight to Lisbon, compare prices on headphones, unsubscribe from some newsletters. And sometimes it does. Open tabs, browse websites, fill out fields. Watching him work is hypnotic. It’s also slow, erratic, and occasionally catastrophic. In a test I asked her to add flowers to a store cart. Instead of somehow inferring my zip code or asking me about it, he directly introduced 28001: madridcentrismo to the song. While I, helpless, did click on the correct options that I was completely unaware of. There is no way to correct it while working. You can only watch, like someone who sees their autonomous car getting dangerously close to the cliff. A zip code just because, 350 km from my house. Image: Xataka. Neon spent an absurd amount of time wandering around the web, adding the bouquet to the cart, getting stuck on the shipping zip code, not feeling like anything productive was happening. Image: Xataka. Another example with Do: Image: Xataka. What he did was open Google Shopping, enter the term and not be able to click ‘Search’, apparently due to some subtle change in the website’s code. I gave it myself and Neon continued. It took a long time just to choose the order by price from lowest to highest. Finally he wrote the answer: Image: Xataka. Happy ending, although it is difficult to think of use scenarios where the use really compensates for the time and supervision it requires. If someone doesn’t know about Google Shopping, this is a good use case. If someone knows Google Shopping, they only have to do two clicks. Another example: reading some recipes Straight to the PalateI asked him to add all the ingredients necessary to make them to the Mercadona cart. Let’s go to trouble. Image: Xataka. Image: Xataka. This was one of those scenarios where there was no way I was going to complete the mission. Image: Xataka. Make is the most ambitious. Generate code, build web applications, create videos. I asked him for a memory game with Spanish vocabulary and he did it in minutes. Rough, but functional. It’s like having a mini-developer living in your browser, working in a virtual environment that disappears when you close the tab. A brilliant idea. A little polished perhaps, but brilliant. Image: Xataka. There are also the cardsa kind of templates prompts that function as mental shortcuts. You can combine them – “summarize + compare”, “decisions + follow-up” – or create your own so you don’t start from scratch every time you talk to the AI. It’s a simple but powerful idea: it makes user learning part of the system. Similar to what you propose Day with his Skills. It’s a good idea. What is not being said about Opera Neon Here comes the part that interests me the most, the one I read between the lines after a week living with this thing. Opera Neon is not really a product. It is a testing ground with product pricing. It is a public beta disguised as a premium service. And that wouldn’t be so much of a problem if it didn’t cost $20 a month. Let me be clear: I’ve seen enough technology launches to recognize when a company is testing concepts in the open field. And Neon is that. The bugs They are not occasional, they are structural, like the hallucinations. The Do agent disconnects if your computer goes to sleep. Chat responses are verbose. The Cards interface—those shortcuts prompts reusable—is full of examples with no real useful content. Cards examples interface. Image: Xataka. But there’s something more interesting going on here. Opera is making a counterintuitive bet at the worst possible time. We are in 2025: Google gives away Gemini in Chrome. Perplexity has Comet. The Browser Company (Arc’s company) has Day. Microsoft puts Copilot everywhere. And OpenAI recently launched ChatGPT Atlas. … Read more

We have had Stephen King releases for several weeks in a row. Don’t we know how to do anything else?

The fall of 2025 has brought with it an avalanche of Stephen King: almost in consecutive weeks we have had the premiere of ‘The long march‘ and ‘The Running Man‘, and shortly before the series started ‘It: Welcome to Derry‘ on HBO Max. Three great productions in just one month. Are we facing an unimaginative industry that constantly turns to the same author, or is it that King continues to offer something that others cannot? The answer has three keys: the so-called Kingaissance, the decisive factor of the streaming and the current value of King, which has not been devalued by bad adaptations. Debunking the myth. To deny King’s supposed dependence on the horror genre, just look at the last twelve months of releases. Independent horror is enjoying an unsuspected golden age: ‘Longlegs’, for example, grossed more than one hundred million dollars at the box office with a budget of just ten, and films like ‘The substance‘ have given terror a life-long breath of quality, including Oscar nominations. Classic franchises such as ‘Final Destination’ are recovered, ‘Frankenstein’ is sweeping Netflix and a star system from horror creators: the aforementioned Perkins, Prano Bailey-Bond, Danny and Michael Philippou, Zach Creggar and Rose Glass, among others. The Kingaissance. The Anglo-Saxon media coined a term to describe what is happening: the “Kingaissance“, a revival that has a precise birth date. In September 2017, ‘It’ by Andy Muschietti became an unexpected cultural phenomenon: With a budget of just thirty-five million, it grossed more than seven hundred globally, becoming the highest-grossing horror film in history without adjusting for inflation. What followed was an avalanche. Without exhaustiveness: ‘Doctor Sleep’, ‘Animal Graveyard’, ‘Eyes of Fire’, ‘Salem’s Lot’, ‘In the Tall Grass’, the series ‘Apocalypse’ and ‘Chapelwaite’… And now, three more adaptations, to which will be added the future television ‘Carrie’ by Mike Flanagan, ‘The Talisman’ for Netflix and perhaps a new ‘Cujo’. The difference with the eighties is abysmal. Back then, TV movies and B series predominated: now they are series on HBO and films with established directors. King himself often has creative control and serves as executive producer on many of these projects. The factor streaming. For decades, adaptations of King’s longer novels have been handicapped by having to compress their length to the margins of the feature film. He streaming changed the rules of the game: platforms now allow series of eight or ten episodes that respect the author’s narrative complexity, something that had previously only been experienced in miniseries format, in productions such as the first version of ‘It’ or ‘The Store’. It happened with ‘11.22.63’, with ‘The Stranger’, with ‘Lisey’s Story’ (which King personally wrote)… Now it is the turn of the prequel to the latest version of ‘It’, and it is clear how the logic of the platforms works: they look for recognizable IPs, and King offers dozens of stories with a bomb-proof dramatic structure. But there were bad adaptations of King. And they didn’t kill the goose that laid the golden eggs. It’s always happened: there are adaptations in miniseries format in the nineties, like ‘The Langoliers’ or ‘The Shining’ that are a pain. Since the nineties there have been as many weak King films as there have been notable ones. Very recent is the horrendous ‘The Dark Tower’ from 2017, which compressed eight novels into 95 disastrous minutes. Or ‘Cell’, absolutely forgettable. Why didn’t these catastrophes sink King’s value? First, the original novels remain, at worst, more than readable, and at best, downright excellent: the source material is indestructible. Second, readers clearly distinguish between author and adaptation, continue to appreciate the writer, and continue to try their hand at adaptations. Third, the good adaptations (‘The Shining,’ ‘Carrie,’ ‘It,’ ‘Misery,’ the original ‘Pet Sematary’) are so good that we’ll always come back for more. Why we return to King. The answer, despite appearances, is not a lack of ideas, but rather that we are faced with a name of proven effectiveness, even in its worst moments: few have that commercial hook combined with minimum standards of quality and entertainment. King has more than 65 novels and 200 short stories, an inexhaustible mine whose themes will never go out of style and are universal: generational traumas, addictions, the problems of the working class, invisible threats, the corruption of power, the weight of our past… And to top it off, we are in the era of the IP. So it is not an issue that affects only him. Marvel, DC, Disney… In 2024, the ten highest-grossing films They all came from pre-existing intellectual properties. And Hollywood seeks familiarity: from the Agatha Christie films directed by Kenneth Branagh to the explosion of video game adaptations like ‘fallout‘, ‘The Last of Us‘ and ‘Super Mario Bros.: The Movie‘. An ideal scenario for a brand that, undoubtedly, has had its ups and downs, but that right now enjoys unexpected iron health. In Xataka | There is a book by Stephen King that sells for around 100 euros and I got it for five: the strange story of ‘Rage’

We are discovering how the brain “hacks” us to make us hungry. And it is a key step in the race towards losing weight.

Right now, treatments to lose weight are the order of the day, with a clear protagonist like Ozempic. The problem is that beyond the aesthetic effects that are achieved, there are many doubts about both the side effects as well as all the effects it has on the body. But little by little science you understand much better how they achieve their effectwhich seems like a real miracle for many. What we knew. In general, these treatments They are ‘copies’ of GLP-1 which is a hormone that we produce normally in our body and makes us have the feeling of satiety. The moment we increase it exogenously we have a greater feeling of satiety that allows patients to lose weight (although with a risk of bouncing when treatment is stopped). But beyond this effect, the action it could have directly on the brain was something that had only been explored in animals. Now, a new study published in Nature has crossed this frontier thanks to Casey Halpern’s team, which has taken advantage of a “unique opportunity” to observe, for the first time in humans, the impact of Mounjaro (tirzepatide) directly into the reward center of the brain. Why it is important. The discovery of how the brain can ‘hack’ our body to eat much less opens many doors for us in the field of pharmacology to be able to continue working on definitive treatment. against obesitybecause we are seeing that it is something in high demand by many people who find it necessary to have this help (although it is not a miracle) to be able to reduce their weight. And we even see how in the United States purchasing is becoming more and more accessible. And we say that it is a miracle, because Ozempic or Mounjaro does part of the work, but we must not leave aside the change in eating habits to adjust the diet and be able to maintain it after stopping the treatment. The problem is that there are people who after stopping the treatment continue eating normally, and logically they see that there was no miracle involved. How it was done. The study focused on a 60-year-old woman with treatment-resistant obesity and type 2 diabetes. This patient was already taking Mounjaro for diabetes, and coincidentally, she was participating in another trial to treat dysregulated eating. This coincidence allowed the researchers to do something unprecedented: use the electrodes, already implanted in its nucleus accumbens (NAc)for hear brain activity while the drug took effect. And this brain nucleus is really important as it is the center of pleasure in humans and reward, that is, it is the point that can be modulated to restrict food consumption. The sign of craving. Those cravings we have for eating a little chocolate, a greasy pizza or a hamburger are something we all have because it is what gives us pleasure. In this case it was seen that the signal changed over the months, specifically the delta-theta frequency band. In the first months of treatments with Mounjaro, the patient had no desire for food in that sense of craving. Something that corresponded to a null signal in this nucleus, so it could be said that the medication was silencing this ‘noise’ that is generated in the pleasure center. The problem is that in the fifth to seventh months, despite being on the maximum dose of medication, the patient again had severe concern about food. And here again the signal in the nucleus had spiked to match that of those people who had no treatment. An advantage for the future. The most important finding here is that the change in the brain preceded the behavior. That is, before having a relapse this signal was increasing as if it were a warning signal. That is, a future where a sensor can detect this brain signature and alert the patient or doctor that the effectiveness of the drug is decreasing, before that the person will feel the cravings again in an uncontrolled way. Much ahead. This is a study with a single person, and it has many limitations and its conclusions logically cannot condition the clinical activity of the use of these medications. What it is useful for (and a lot) is to understand that the brain has a lot to do with this weight loss as if it were a real button to control eating habits. Perhaps silencing this brain nucleus in a very specific and sustained way may be the ‘holy grail’ that weight loss science seeks to control these cravings that can ruin a diet imposed by specialists. Although there is still a lot to investigate and it is only a first door for other medications that can complement Ozempic or Mounjaro, which has given great results. Images | Shawn Day Victoria Shes In Xataka | This is the great hope of the competition to replace Ozempic. Your weapon: banish needles with a pill

The bloodiest scene in the history of cinema left its protagonist in shock. 50 years later we know it was real

Stephen King told that, for him, his Carrie It was like a pig taken to the slaughterhouse, and the blood of the animal reinforced the metaphor anticipating the massacre that would follow. Hence when the novel became a film, the most recognizable scene was the most visceral, organic and unpleasant of all. A gore moment that became celluloid history. The blood that changed terror. The Legend of Carrie (the movie) is born at the moment when a thick mixture of corn syrup and red food coloring falls on actress Sissy Spacek, a moment that has transcended horror cinema itself to become a cultural icon. The construction of the scene (the coronation interrupted by the explosion of humiliation and fury) concentrates the essence of a film that turned the artificial into something emotionally real. He Karo syrupheir to decades of cinematic experimentation with fake blood, here acquired an unexpected meaning by becoming the visual and psychological trigger for Carrie White’s transformation. Anniversary. Now that 50 years have passed since the original film, Spacek has remembered that that substance “warm as a blanket” in the first seconds soon became an exhausting, sticky and repetitive experience, forcing her even to sleep with the bloody suit so as not to have to reproduce the makeup application. But precisely that physical surrender, with its almost immobile and tragic presence under the weight of the thick liquid, is what granted to the plane that kind of mythical quality: the border between artifice and emotion is erased, leaving only the fixed gaze of a broken teenager who feels, for the first time, that the whole world is laughing at her. The infernal filming of a scene. The Independent said It’s been a few years since the prom sequence required almost surgical precision. Although the rest of the scene required more than thirty takes, the exact moment of the blood spill could only be filmed once or twice due to the impossibility of cleaning and recomposing the set. Spacek even accepted that it was her own husband who operated the cube mechanism to ensure that the fall was perfect, knowing that her interpretation would depend on how she received that hit of red viscosity. The fake blood was a physical enemy but also a dramatic element on which the story completely depended: its texture, shine, the way it adhered to the actress’s body and soaked her dress, everything contributed to giving the impression that something irreversible had happened. In fact, many of the scenes we saw ended up being very real: a stage that ended up accidentally burning, a team evacuated while the director I asked to keep rolling and injuries such as the perforation of an actress’ eardrum during the attack of the launched hose telekinetically by Carrie. What should have been millimeter choreography became an almost ritual experience, in which fire, destruction and general chaos seemed to respond to the internal logic of the film itself. The unexpected myth. Despite initial doubts, the rejection of critics who considered it a sensationalist spectacle and the fact that even the name of Stephen King appeared poorly written In the first previews, Carrie ended up transforming into a phenomenon. Its mix of operatic stylization, black humor, adolescent cruelty and symbolic violence connected with a much wider audience than expected, inaugurating a type of youth horror cinema that is still alive several generations later. For King, a small-town teacher who had thrown away the first pages to the garbage can before being rescued by his wife, the film marked the beginning of a hyperbolic race. For director Brian De Palma, it was the definitive consolidation of his baroque style, obsessed with the gaze, visual manipulation and expressive excess. A unique role. Of course, for Sissy Spacek, work meant an Oscar nomination and lasting recognition for a performance that combined absolute vulnerability and unleashed rage. On a personal note, I would say that none of the later remakesreinterpretations and adaptations managed to capture that mixture of innocence, evil and contained tragedy that the original became its hallmark. The validity of a story. The truth is that with the passing of the decades, Carrie has not lost strength. Quite the contrary, its contemporary reading resonates in a world where school violence, public humiliation and the feeling of youth isolation are part of the collective imagination. the movie speaks of the ritualized cruelty of adolescence, of vulnerability to changes in the body and of a universal feeling of maladjustment that Spacek described a few days ago on CNN like that “wounded teenager that we all have inside.” The combination of emotional realism and the tone of a dark story, almost biblical in some passages, turns the story into more than just an exercise in terror. The presence of a fanatic mother, the brutality of her classmates, and Carrie’s own inability to understand what is happening to her allow the story to oscillate between melodrama, religious parable, and Greek tragedy. The visual references, the use of color and the stylization of the final climax consolidate an imaginary that continues to define how psychological horror is filmed. in adolescence. The weight of artifice. Five decades later, Spacek’s memory of filming it’s contradictory: the physical hardness of the process, the exhaustion of wearing hardened layers of corn syrup, the extreme discomfort of the long days and, at the same time, the privilege of having worked on a project where each member of the team was dedicated to something that they did not know would transcend. That mix of technical suffering and unfiltered creativity explains why the blood scene has become an immutable symbol of horror cinema. What began as a practical necessity (creating cheap, realistic, and manageable gore) ended up leaving an indelible mark on how emotional violence is portrayed on screen. Perhaps for this reason, Carrie remains a most accurate study in fragility, repressed rage and the devastating power of humiliation, but also as a demonstration that even a sticky, artificial substance can, in … Read more

how much science believes our longevity will actually increase

Society is increasingly obsessed with living longer and longer and have an aesthetic that corresponds to a younger age. Right now there are many really eloquent projects to achieve practically immortalitybut this makes us wonder if our body has some kind of limit that cannot be exceeded. This is what science tries to elucidate. Nowadays, people who live more than one hundred years are something extraordinary, and we even see their centenary birthdays appear on the pages of the newspaper or on local television programs. But the question in this case is whether the new normal will be being able to live more than a century as something normal, and above all in good conditions. But the truth is that we are far from achieving this. Two concepts. The first thing to understand here is the difference that exists between the average life expectancy and maximum longevity. The first of these is growing spectacularly in the last century thanks to vaccines, hygiene, medications and better access to healthcare (although this reaches an older population, with its problems). But when we talk about maximum longevity we cannot say the same, since it is a much harder ceiling to crack. The obligatory question in this case is clear: where is our ceiling that we cannot break? Less than expected. There is now solid scientific evidence that suggests that human beings have a “factory” biological limit. Different studies, such as those published in Nature, they placed the natural human limit around 115 years. Although more recent and optimistic reviews, based on statistical modeling of the “supercentenarians” (people over 110 years old), extend that range up to 125 years. Therefore, we are not facing a scenario of immortality, but rather the age progression curve begins to stabilize at a specific point. And this is clearly a brake that biology itself is imposing on us, because our body has a very clear limit in its functioning. Prioritize well-being. Reaching the age of 120, but with very poor health, with many illnesses behind you or without being able to move, is not something at all attractive. That is why demographic projections for Europe They suggest that, by the year 2065, life expectancy will be between 87 and 93 years. This doesn’t sound like science fiction, and that’s precisely why it’s relevant. It is not about making quantum leaps through unproven gene therapies, but about the accumulation of medical and social improvements. The goal of modern longevity medicine is not for you to live 150 years connected to a machine, but to extend the “healthspan“, that is, the period of healthy life. We already know the ‘secret’. While we wait for drugs that reverse old age, science tells us that we already have the “technology” to maximize our lives and it has been used for decades in the so-called ‘Blue Zones’ of Okinawa as a standard. And it is precisely in this area that people It is capable of easily reaching 100 years without much problemand the question was obligatory: why here? We found the answer in studies carried out in this areait can be seen that the factors that influence being able to reach 100 years of life have nothing to do with transfusions of young plasma, blood cleansing or super-expensive therapies that promise miraculous results. Among the habits that follow we can find the following: Natural calorie restriction: They consume 10-15% fewer calories than an average Western adult. And we already know that this influences above all the generation of oxidative stress which is a great ‘poison’ for our body. The good carbohydrate diet: their diet is based on vegetables and complex carbohydrates such as sweet potatoes, with a very low animal protein intake. Youth biomarkers: the combination of diet and constant physical activity results in a lower incidence of chronic diseases. Less stress: another great poison for the body due to its involvement in cortisol levels. In Okinawa, community cohesion acts as a buffer for stress. The importance of habits. In this way, the scientific horizon for the next century does not promise immortality. It is likely that we will continue to see a trickle of individual records and exceptional cases of genetics that cause us to see people who far exceed the century of life. But for most humans, This is not something we get. (or at least with a good quality of life). The true longevity revolution in the 21st century will be to make reaching age 90 the norm and not the exception, applying what we already know works: moving, eating less (and better) and maintaining strong social ties. And above all, do not wait for a magic pill, as has been demonstrated by the habits of Japanese people who have achieved an effect that no gene therapy has achieved so far. Images | Ravi Patel In Xataka | Not all brain cells age at the same time: we have found a “hot spot” of aging

Log In

Forgot password?

Forgot password?

Enter your account data and we will send you a link to reset your password.

Your password reset link appears to be invalid or expired.

Log in

Privacy Policy

Add to Collection

No Collections

Here you'll find all collections you've created before.