key

The Granada particle accelerator is born today. Thanks to him Spain has the key to nuclear fusion

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Today is a crucial day for IFMIF-DONES (International Fusion materials irradicion facility demo-eraned neutron source). This very important scientific project is closely linked to ITER (International Thermonuclear Experctor reactor), The experimental reactor of nuclear fusion that An international consortium led by Europe He is building in the French town of Cadarache. Ifmif-Dones, however, resides in listening to, a town in the province of Granada. The construction works of this last installation began in mid -September 2022, but today it is a very important day for both Granada and all of Spain. And it is because the Council of Ministers will approve today the investment of almost 200 million euros required by the start of the construction of the IFMIF-DONES linear particle accelerator. This machine is the authentic heart of this scientific installation, and, therefore, the ingenuity that will place Spain in The nuclear fusion map. The tuning of this linear particle accelerator will cost approximately 450 million euros, although the Andalusian Board will contribute half of this money. However, this is the cost of the accelerator; The IFMIF-Dones project will completely cost about 700 million euros. Spain will contribute half of this capital. To this figure we must add another 50 million to carry out its implementation. In addition, the operation of this avant -garde research center will have an annual cost of about 60 million euros, of which Spain will assume 10%. It may seem a lot of money, but we must not forget that those responsible for the project are convinced that The economic and scientific return Ifmif-Dones will far exceed your cost. What is Ifmif-Dones and why it is crucial for the future of nuclear fusion Ifmif-Dones is one of the three fundamental pillars of the nuclear fusion building in whose construction the European Union is involved. The other two are iter and demo. The experimental nuclear fusion reactor that is currently being built in the French town of Cadarache seeks to demonstrate that the merger at the scale that man can handle works, and also that it is profitable from an energy point of view. However, Iter does not aspire to produce electricity. That will be demo’s task (Demonstration Power Plant), an installation that will take the technological advances that will have shown to function correctly in Iter and take them one step further to establish themselves as The authentic precursor of commercial nuclear fusion reactors. However, without Ifmif-Dones there will be no demo, so Granada is now the center of attention. The fusion of a deuterium core and another tritium triggers the production of a helium core and a neutron that is fired with an energy of about 14 MEV To understand in all its extension what is the role of the IFMIF-DONES project, it is necessary that we briefly review the foundations of nuclear fusion. One of the biggest challenges facing the technicians who are involved in the tuning of nuclear fusion reactors by means of magnetic confinement, such as Iter, consists of recreating inside the vacuum chamber of these sophisticated machines the necessary conditions so that the deuterium and tritium nuclei are merged. However, this is not everything. When this reaction takes place the fusion of a deuterium nucleus and another of tritium triggers the production of a helium core and a neutron that is fired with An energy of about 14 MEV (Megaelectronvolts). The problem is that the neutron lacks net electric charge, so it cannot be confined inside the magnetic field that, however, does retain the deuterium and tritium nuclei, which have positive electric charge. This is the reason why when it originates as a result of the nuclear fusion reaction, this neutron is fired towards the walls of the vacuum chamber with enormous energy. This particle is very important because in practice it will be closely linked to the production of electrical energy in nuclear fusion reactors, but, at the same time, it represents a very aggressive form of radiation that can significantly degrade the materials used in the reactor. The components that will be most affected by the direct impact of high energy neutrons and the most intense heat flow are the internal wall of the vacuum chamber and the Blanketthat it is a mantle that covers it and that has as its purpose Regenerate the tritium that it is necessary to use as fuel in the nuclear fusion reaction. This is the reason why it is crucial to develop new materials that are able to support the flow of neutrons and guarantee, therefore, that the reactor will have a prolonged operational life. IFMIF-DONES linear accelerator will produce high energy neutrons with the intensity and volume of irradiation necessary to test candidate materials This is, neither more nor less, the purpose of Ifmif-Dones. And to carry it out it is necessary to put ready -to -set facilities to allow the technicians involved in the project to evaluate the properties of candidate materials to intervene not only in demo, but also in future commercial nuclear fusion commercial reactors. The task of this project invites us to intuit what the heart of Ifmif-Dones is: a source capable of producing high energy neutrons with the intensity and volume of irradiation necessary for Test candidate materials. And this source of neutrons will be nothing other than a linear particle accelerator that will help IFMIF-DONES scientists to try, validate and qualify the materials that in the medium term should reach future electric power production plants through fusion. Image | IFMIF-DONES In Xataka | Iter has faced one of the great challenges of nuclear fusion: prevent plasma from 150 million ºC to destroy the reactor

Losing weight without losing muscle is the great challenge of drugs such as Ozempic. A protein keeps the key to face it

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It is usual for us to often get news about hopeful scientific advances made in mice. These experiments always leave a question in the air, if the discovery can be applicable to humans. This does not always happen, but sometimes MITCH Silence the expression of a simple protein in our muscles can lead to weight loss and, more, more, It can allow us to lose weight Without putting our muscle mass at risk. The protein in question is called Mtch2 (Mithochondrial Carrier Homolog 2), but has been nicknamed “Mitch” by those who study the compound and its effects. The last analysis of this protein and its associated gene has observed that its “erased” in human cells causes in these lower efficiency Energy What is perhaps more important, this silenced causes cells to stop using carbohydrates as a priority energy source and in place they preferably use body fat. Different fuels. The cells of our body need energy and billions of years of evolution have given rise to a series of biological mechanisms that allow us to maintain a calorie reserve that allow us to feed these cells in times of greater shortage. These mechanisms imply that our cells can resort to different fuels according to the situation. While the carbohydrates we consume and the fats that we use as a reserve are the main fuel Ozempic. From mitones to mitochondria. According to Explain the responsible teamthe new study has its bases in a previous experiment conducted with mice that observed in the rodents an “improvement” in their body composition in the form of “protection” against obesity and the development of more muscle fibers. This accompanied by greater consumption of greater oxygen consumption and an increase in resistance. The results were promising but left the team with a doubt, if it would be possible to “inoculate” the body against obesity by silencing the expression of a protein without this negatively affecting muscle mass. To look for an answer, the team went on to focus on the role of the mitochondría, the organelle in charge of providing energy to the cell. The key is in the fact that the “mitch” protein plays an important role in the merger of the mitochondria, a fusion capable of increasing the efficiency of these organelles. By silencing protein, organelles would lose the ability to resort to this fusion which also implies less efficiency and thereby a greater need to consume energy resources of our body. It only remained to prove if this was also true in human cells. Less efficiency, more consumption. They thus verified that by silencing the protein in human cells, the “mitochondrial network” was undone and, as expected, energy efficiency fell. This left the cell in a “permanent state of energy deprivation.” And what is more, the team also found that this led to the cells to prioritize the use of fats as a primary energy source, instead of other possible sources such as carbohydrates. “After erasing Mitch, we examined, every few hours, the effect that it had in more than 100 substances that take part in the metabolism of human cells,” pointed in a press release Sabita Chourasia, co -author of the study. “We saw an increase in breathing, the process in which the cell produces energy from nutrients, such as carbohydrates and fats. This explains the increase in muscle resistance of previous experiments in mice.” The details of the study were published In an article In the magazine Journal embo. An intermediate step. The study takes an important step in the long process between the first results in animal models and the design of a treatment for weight loss based on what was learned. In following studies, the team intends to elucidate new aspects about Mitch’s role in the accumulation of fat in the body. The fact that women usually have higher levels of this protein can help researchers discover if Mitch is also responsible for the differentiation of fatty cells. In Xataka | We are increasingly clear that our microbiome is key to our health. Our protein sources can also alter it Image | Weizmann Institute of Science

Nothing has managed to find the key in the mid -range. Its new mobile is very striking, very cheap and includes headphones

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When Nothing launched the CMF Phone 1 I knew that I had to be attentive to this sub -woman. Time has proved me, because the CMF Phone 2 Pro It has been released to stores with a very contained price and with an excellent configuration. Can be found in Amazon by 249 euros In its 128 GB version, it includes bluetooth headphones CMF Buds 2 And … a lot of eye with everything it offers. CMF Phone 2 Pro (128 GB) + CMF Buds 2 * Some price may have changed from the last review An excellent mid -range mobile for less than 250 euros He CMF Phone 2 Pro It is a mid -range mobile that stands out mainly in three sections. The first is, unquestionably, the design so striking that in some way Nothing has maintained with respect to the previous generation. And attentive to customization, because You can connect a cardboard, a cord and even interchangeable objectives. It also stands out for your screen. In the mid -range we do not usually find mobile phones that have a similar configuration, since the CMF Phone 2 Pro includes a screen 6.77 inches AMOLED With FullHD+resolution, 120 Hz refresh rate, 3,000 nits peak brightness and compatibility with compatibility with compatibility HDR10+. In addition, it is also worth mentioning that the CMF Phone 2 pro comes with the Essential Key/Spacea space that is enhanced by which we can save both voice or text notes and screenshots. It is accessed by the button that we find on the side of the mobile. You may also interest you Giopuey compatible with CMF Phone 2 Pro, TPU material is ultra -the case (wear resistant) (non -slip) Cover – black * Some price may have changed from the last review * Some price may have changed from the last review Some of the links of this article are affiliated and can report a benefit to Xataka. In case of non -availability, offers may vary. Images | Ricardo AguilarNothing In Xataka | The best mobiles, we have tried them and here are their analysis In Xataka | The best price quality price. Your analysis and videos are here

Baidu believes to have the key and has registered it in a new patent

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The idea of ​​talking with our pets has been feeding the collective imaginary. And although we continue to maintain a conversation with a dog or a cat in the style of Doctor Dolittleartificial intelligence (AI) begins to explore a much more realistic land: to interpret how they feel. The last sample comes from China: BAIDU has requested a patent proposed by a system capable of translating the emotional state of animals into understandable language for humans. An emotional translator, not a talk with your dog. The application, submitted by the company to the State Office of Intellectual Property of China raises a system that does not intend to translate barking or meowed in human phrases as if they were words, but to identify relevant signs of animal behavior (such as voice, gestures or physiological changes) to estimate its emotional state and express it in natural language. In other words: it’s not about talking to animals, but better understanding what they feel. As Sina collectsthe key is to build an emotional interpretation channel that allows humans to react to what animals, obviously, cannot express in words. The difference with respect to other existing tools is in the depth of the analysis. Most initiatives in this field focus on the superficial interpretation of sounds or expressions, but do not capture complex emotions. Baidu’s proposal aspires to break that limit. Artificial intelligence with multimodal approach. The system key is in its integral approach. According to the technical summary of the patent, the method relies on technologies such as automatic learning, deep learning and natural language processing. These three pillars allow to process large volumes of data and extract relevant patterns in real time. Innovation is how the different signs collected are combined: vocalizations, postures, behavioral variations and physiological data. All this is analyzed jointly to avoid errors that usually occur when it is based on a single source. The ultimate goal is to achieve a more precise emotional reading, with less margin of ambiguity. Applications in Care, Conservation and Animal Study. The potential use of this technology goes far beyond the domestic sphere. According to the document, it could be used to improve the welfare of pets, adjusting their care and company based on their mood. But it could also have an important role in scientific research, helping biologists to better understand the behavior of rare or endangered species. In reservations and conservation centers, these types of tools could become an ally to anticipate states of stress or discomfort before they manifest themselves in an evident way, facilitating the task of the staff. It is not yet a product. As with any patent, its publication does not imply that technology is available or becoming a commercial product. In fact, South China Morning post points That the evaluation process can be extended for more than a year, and Baidu has not announced concrete plans to develop it in the form of a device or service. For now, what the company poses is a technical basis that opens a new chapter in the relationship between humans and animals. One in which, perhaps, we can begin to understand more precisely what those who cannot talk to us with words feel. Images | Stephen Yu | Werzk Luuuuuu In Xataka | Loneliness is already a matter of public health. We have more and more evidence that animals help us to placate it

Hyundai aims to automate 40% of his new plant in the US. THE KEY TO GET IT: ATLAS HUMANoid Robots

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Robots have been in the automobile industry for decades. They have welded, pressed and assembled pieces without rest. But despite that long career, many tasks were still in human hands. That is starting to change. Robots are less and less clumsy: They are more skilled, more versatile and, most importantly, much cheaper to manufacture. And that opens the door to a new phase. Hyundai wants to be in charge of that change. On your new plant HMGMA (Hyundai Motor Group Metaplant America), located on the outskirts of Savannah (Georgia, USA), the company has proposed to automate 40% of the vehicle assembly process before the end of 2025. According to Nikkei Asiathe objective is to transform this factory into an intelligent environment, where artificial intelligence and data are key from logistics to the final assembly. A connected and flexible ecosystem. The plant is designed not only as a assembly line, but as a demonstration of everything Hyundai is able to do with technology. The brand defines it as “a highly connected, automated and flexible manufacturing system”, prepared to adapt to changes in demand and optimize each phase of the process. That is why it is no coincidence that starts focused on the production of electric and hybrid vehicles, with an estimated initial capacity of 100,000 units a year, which will grow to 500,000 when it is at full performance. The Metaplant aspires to become one of the referents of the automobile industry of the present and the future. Atlas enters the scene. In that technological deployment, the focus is on a very concrete protagonist: Atlas, Boston Dynamics’s humanoid robot. It is not any robot. It is a completely electric model, designed to move as a human and work in the same space as humans. Atlas is the successor of the famous hydraulic model that we saw mortal somersaults. But this time, the approach is another. It is prepared to lift heavy objects, install parts and adapt to what happens around you in real time. Hyundai describes it As a robot with “athletic intelligence”, and that translates into sensors, algorithms and a structure designed for complex tasks that one person could only do. Boston Dynamics is already part of the Hyundai group. This movement makes sense because Boston Dynamics is not just any partner: It is part of the Hyundai group since 2021. Since the company was made, the South Korean firm has been integrating its technology within its vision of “progress for humanity.” A vision that includes autonomous cars, urban air mobility, robotics in logistics and, of course, new ways of manufacturing. Boston Dynamics has been working with biped and quadruped robots for years, and now faces the challenge of taking them to the commercial field. If Atlas works in this plant, it will mark a before and after. Because it is no longer just impressing in a viral video: it is about a robot being useful and productive on a large scale. What tasks will the robots perform? Hyundai has not detailed all the works that Atlas will assume, but, according to the aforementioned Asian newspaper, it has confirmed some: move heavy objects, install doors in vehicles and collaborate in physical tasks that require strength and precision. The objective is clear: to free human operators from repetitive or demanding works. Now, that does not mean that Atlas is just as agile as an expert operator. For now, it is not. Just see some assembly line videos To ask ourselves if robots will be as skilled as humans. Atlas will not be the only one in the plant. They will also deploy The well -known spotdog -shaped robots that also manufactures Boston Dynamics. Its function will be to monitor production lines, inspect bodies and identify possible structural defects. And next to you they will live more classic automation systems: welding robots, presses and heavy machinery. A context marked by the tariff war. This deployment does not happen in a vacuum. It arrives in the middle of the commercial war between the United States and China. The administration Trump has imposed a 145% tariff To many products from China and maintains a base rate of 10% for most commercial partners, including South Korea. That is why Hyundai has decided to bet on American territory. Has announced An investment of 21,000 million dollars in the United States over the next four years. A strategy that seeks to protect its position in the North American market and, at the same time, gain margin of maneuver against geopolitical uncertainty. Of course, automating more does not necessarily mean hiring more. Hyundai’s expansion is accompanied by strong robotization. And that raises questions about employment. Will less operators be hired? Will new roles emerge within factories? The advance is indisputable, although it does not guarantee new jobs. Images | Hyundai In Xataka | Duolingo inaugurates a new era: when human talent is no longer essential

His future Baza will be in two key cards that promise to change air combat

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Imagining a combat plane of the future is not difficult. The difficult thing is to build it. That is precisely the ambition behind the storm: a sixth generation hunt that does not intend to resemble current airplanes, but to rewrite how air combat is understood. The project, promoted by United Kingdom, Italy and Japan within the framework of Global Combat Air Program GCAP, does not pursue only a technical evolution. It is a declaration of intentions on technological sovereignty and defense. Tempest is not a simple new generation hunting. The Royal Air Force defines it as “The heart and mind connected to an air combat system”, Able to integrate sensors, weapons and data into a single operating flow. In other words, the Tempest is not only a platform with wings, but the center of command of a swarm of technologies that communicate with each other to make decisions faster. The future hunt seeks to act as the tactical brain of an operation. That translates into a series of simple requirements. One of the most important is autonomy. As explained in the official podcast of the programthe storm aspires to reach a “really extreme” range, wide enough to cross the Atlantic without reposting. At the moment it is an objective under study, not a closed requirement. This autonomy would seek to allow prolonged operations without depending on cistern aircraft, in scenarios where to enter and leave the enemy territory is less challenging. The other key requirement is load capacity. The objective, according to the words of the director of the Team of Requirements and conceptualization of the United Kingdom Ministry of Defense, is that it exceeds that of the F-35even reaching Duplicate your total armament capacity. There is no precise figure on the table. What is safe is the ambition to turn the Tempest into a platform that integrates not only more missiles, but also advanced and electronic war sensors, without compromising its stealth profile. The hunting that wants to be brain, muscle and network From the beginning, the design of the Tempest revolves around the idea of ​​a digital ecosystem. BAE Systems, Leonardo, Rolls-Royce and MBDA are working on technologies that are not limited to fuselage. The program is structured around systems such as Isanke (Integrated sensors and non -kinetic effects) and ICS (communications), that will form an intelligent network between fightersdrones and other assets of the battlefield. The goal is for the pilot to have more information, more context and more reaction options than any adversary. An F-35 Florida (left), render of the storm (right) All this requires power. Propulsion power, but also electric. As explained Rolls-Roycethe new propulsion system Not only will the plane movebut it will generate sufficient electricity to feed advanced sensors, electronic war systems and, probably, Laser weapons. The architecture will be open, modular and prepared to receive updates over time, something key in an environment where military technology changes every few years. Manufacturing tasks of the main structure (left), motor tests (right) That approach also moves to the manufacturing process. The project is betting on digital engineering techniques, automation, real -time modeling and simulation by digital twins. The technology demonstrator, which is already built in Warton, will serve to validate all that approach. According to BAE Systems datamore than half of its structural weight, including fuselage and wings, is already in production. In addition, the British Ministry of Defense has confirmed that Part of technological development includes experimental recycling of tornado aircraft components. The so -called project ‘Tornado 2 Tempest‘He managed to successfully print pieces such as a nose cone and blades for a test engine. This is a proof of concept that seeks to reduce costs, minimize the dependence of critical metals and explore new manufacturing paths with lighter and more resistant materials. To all this is added the human factor. More than 2,500 people already work in the program in the United Kingdom. Many of them are young engineers trained within the Generation Tempest initiative. As technological advances and international alliances are added, the Tempest ceases to be a concept to become a tangible reality. The expectations are high and we will have to wait to know if they are met. Everything indicates that it will be a hunt very different from everything known. Images | GCAP In Xataka | The F-35 and the US ballistic missiles need the key component of a magnet. The problem is that it was “Made in China”

We are increasingly clear that our microbiome is key to our health. Our protein sources can also alter it

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Little by little We started realizing Of the importance of our microbiota, especially as regards the microorganisms that inhabit our digestive system, our gastrointestinal microbioma. Aspects of our health that in principle They would not seem connected To what happens in our intestines seem to have some kind of correlation with that flora of fungi and bacteria that coexists inside us. Different proteins, different microbiome. A recent study has observed That the food source of protein can alter the composition and structure of our intestinal microbiome, that is, of the set of microorganisms that inhabits our digestive system. The experiment, conducted with mice, observed important variations in the microbiota associated with changes in the diet. “The composition of gastric microbiome changed significantly every time we change the protein source,” pointed in a press release Alfredo Blakeley-Ruiz, co-author of the study. “Protein sources with the greatest functional effects were integral rice, yeast and egg whites.” A variety of sources. Proteins are a key nutrient that gives us essential amino acids with which our body is able to synthesize its own proteins. Foods of animal origin such as meats, fish or eggs are usually seen as the main source of amino acids, but they are not the only one. The existence of alternatives implies the possibility of diverse effects on our health and well -being. Through, for example, of the microbiome. Metabolizing amino acids. The team resorted to its study to the use of high -resolution mass spectrometry and the combination of metagenomic and metaproteinomic. Everything to find how the intestinal microbiome of mice whose diet was altered so that each week they received their single source proteins that was changed after seven days .. They observed that some of these sources were associated with important changes. These changes, Explain the teamthey manifested in how the mice metabolized the amino acids, but also in the way in which their digestive system degraded complex sugars, something that was not so intuitive. Diets such as those based on the integral rice and the clearing of the eggs, continue to explain the equipment, increased the degradation of the amino acids, which would imply that the microorganisms of the digestive system of the mice were breaking the proteins to obtain their own amino acids. The details of the study were published recently In an article in The Isme Journal. An environment (too much?) Controlled. The team responsible for the study admitted That there are some limitations to consider, and one of them is the complexity of the diet. In a laboratory environment, the team altered the diet of the mice radically (causing them to have a single source of protein). Beyond the fact that studies with animal models are not always transposed identically in humans, it is expected that forceful changes in the diet of these animals entail important changes in the structure of their microbiome. A more varied diet, with diverse sources of proteins, would logically imply more dim effects. In Xataka | We have found some supplements capable of improving memory in the elderly: prebiot promising Image | MART PRODUCTION

Who produced the key matters of the world after World War I, in a 1927 graphics

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The end of the Great War He left a totally devastated Europe. France, Italy, the United Kingdom and Germany lost between 25% and 30% of their national wealth and basic agricultural and industrial infrastructure was very damaged. After a first period of recovery just after the end of the war, there was a situation of hyperinflation, monetary depreciation, debt payments to an US that claimed his money and a break in international trade. However, in mid -1920, an economic recovery was lived, and a series of graphics published in 1927 reflects that moment of fleeting splendor just before the Great Depression and of the Second World War. And why not say it, they were a valuable tool if someone with expansionist ideas He threw the glove. Happy twenty years. After the World War IUSA lent money to France and the United Kingdom to rebuild. Germany was punished He pays a rate to those same countries, but when the US claimed the money, the system broke. Germany had no money and France and the United Kingdom needed German funds to pay Americans. However, the Dawes Plan To give a respite to the German economy, so everyone’s debt relaxed and began the “happy twenties.” It was an economic recovery period in which the countries involved reached some stability and, above all, an industrial rebirth. It continued depending on American money and we already know how the decade ended with the breakage of the stock market, but at least allowed European nations to be repurchased in a way. Hickmann Atlas. No levels prior to the Great War were reached, but at least the production and export of raw materials resumed. Beyond Europe, there were many other countries that had been oblivious to the conflict and followed their own path. In 1927, the Austrian publishing house G. Freytag & Berndt published the universal geographical and statistical Atlas of Hickmann. It is a very interesting document because it reflects that panorama of the mid -20s and offers many, many statistics, graphs and maps that are a reflection of the economic and productive state worldwide. We can consult the 80 pages on the web David Rumsey Map Collectionbut from Visual Capitalist They have compiled the most interesting maps in terms of production and raw materials. Land use. The pages dedicated to ‘Produktion’ show precisely that: the most powerful countries in certain types of interesting resources at the time. The first cover the use of the Earth and the graph is divided into: Acherland: Cultivation lands or farmland. Wald: forest. Wieen und Weiden: Praderas and grasslands. Unproduktivland: unproductive land. There are countries like Spain that are very balanced, with large cultivation surfaces and practically identical proportions of the rest, but also striking cases. For example, according to this Atlas, France is the country that, with 56%, more arable land has. They captured that Finland had the largest amount of forests, covering 61% of their territory (in 2021 estimated That was more than 73% and British India was the one that had the most won, followed by the US. And the worst? Norway, with 70% unproductive land. Agricultural production. In Produktion III and IV they focused on land production, and for the Austrians, the US was an agricultural power plant. They were the ones that most wheat, barley, oatmeal and corn produced (by far). The Soviet Union led in Centeno and Germany, obvious, in potato production. Argentina was the second in production of corn and Spain the third in barley. Who had less grain, mattered. Whose? From Argentina, Canada, the United States and Australia, and the great importing countries were the United Kingdom, Germany and Italy. As for wine, France was the spearhead, followed by Italy and Spain. In beer, the United Kingdom marked the pattern, followed by Germany. In that graph, Spain does not appear. In other resources such as Café, Brazil is a lot of difference from Colombia, El Salvador, Venezuela or Guatemala. And China also makes an appearance as a power in the production of tea and rice. Textiles and natural resources. As for textiles, it depends a lot on it. The United States led cotton production, followed by the British and China Indies. Japan and China were silk powers; The Soviet Union and the Philippines were of the hemp culture; The USSR and Poland led the linen, and the hops was a thing of Great Britain and the United States. The oil is a barbarity and, perhaps, the fact that puts us most into perspective with what they thought a century ago. In the Atlas, they indicate that the United States produced about 753,000 barrels in 1923. One hundred years later, US production was 21.4 million barrels … a day during the last quarter of 2023. In tobacco, salt, oil, rubber or paper, Spain has little to say, but where it stands out is in Mercury, very close to Italy and a lot of distance from the United States or Mexico. Mining. Produktion VII and VIII reflects the production of metals, gems and minerals, with South Africa leading the production of gold and diamonds and Mexico that of silver. The United Kingdom had the leadership of gas, but the absolute protagonist in the Serurgy after World War I, and something that would be key to the second, was the United States, leading coal, iron and steel. Cataclysm. The photo for some countries was really hopeful, but only two years after the publication of Hickmann Atlas produced The collapse of the NYSE. This caused the bankruptcy of banks, a reduction in production, protectionist measures and a break in international trade. The US was no longer to lend money to anyone, which caused a worldwide deflation. Europe, which was already indebted to the eyebrows, also suffered this recession, devaluing its coins and causing a new crisis. If a new volume of Hickmann’s work had been published years after the great depression, the situation of the graphics would have been very different. There were some visual … Read more

Many Third-Party cartridges do not bring the game, they include a download key

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One of the advantages most valued by many players of the Nintendo switch original has begun to blur with The arrival of his successor. Until now, physical supports included the game data, which allowed playing directly from the cartridge without the need to connect to the Internet. Of course, the updates were necessary if you wanted to access improvements or additional content. With the Switch 2Nintendo has introduced a new format: the “Game key cards“O Game-Key Cards. These cards must be inserted in the console to play, such as a conventional cartridge, but do not contain the full game. Instead, they store a key that allows you to download the game from the Nintendo servers. That is, Internet connection, storage space and time to install it. It is not new, but now it impacts. The existence of this format was announced in a Nintendo Direct, but at that time it was not known how much the rules of the game would change. Now we are seeing it: Gematsu has pointed out That most third-party games announced in Japan for Nintendo Switch 2 will arrive in Game-Key Card format. Information that has been replicated by means as VGC and Nintendo Lifewhich has given it greater visibility. To know if a game is in this new format, just look at the lower left corner of the box: a key-shaped icon indicates that it is a Game-Key Card. Some of the games that will arrive in this format are: ‘Bravely Default: Flying Fairy’ ‘Daemon X Machina: Titanic Sion’ ‘Kunitsu-Gami: Path of the Goddesss’ ‘Puyo Puyo Tetris 2s’ ‘Raidou Kuzunoha vs. The Soulless Army Remaster ‘ ‘Shine Post: Be your idol!’ ‘Sonic X Shadow Generations’ ‘Street Fighter 6’ ‘Suikoden I & II HD Remaster’ ‘Survival Kids’ ‘Yakuza 0: Director’s Cut’ Only two games presented so far in Japan for Switch 2 include complete data in the cartridge: ‘Rune Factory: Guardians of Azuma’ and ‘Story of Seasons: Grand Bazaar’. Both are titles in Nintendo Switch 2 Edition version. What is a Nintendo Switch 2 Edition? Games under the label Nintendo Switch 2 Edition They are existing titles that are launched next to a specific update package to take advantage of the capacities of the new console. That is, they include the original game and an improvement patch adapted to Switch 2 hardware. CD Projakt has confirmed that ‘Cyberpunk 2077‘It will be launched in traditional cartridge. But in stores like Smyths Toys either Amazon USA You can see Game-Key Cards in games such as ‘Hitman: World of Assassination’, ‘Street Fighter 6’ or ‘Bravely Default: Flying Fairy’. The community responds. In social networks, the reaction has not been waiting. The check “Does it play?” He criticized that this format leaves players “without property, without conservation, without choice.” Other users alert of a scenario where physical games are losing ground. A Game-Key without access to eShop becomes a little useful object. If the game is not stored in the cartridge and the servers fall or close, there will be no way to download it. The theory: Nintendo is limiting the options? On pages like Reddit And YouTube is speculated with that Nintendo could be offering only two cartridge options: one very small and another of 64 GB. Without intermediate options, many studies would opt for Game-Key Cards to avoid high manufacturing costs. Of course, for now, all this are just conjectures. Nintendo has not confirmed anything. Images | Nintendo | Screen capture In Xataka | If the question is “you will sell the Nintendo Switch 2 despite the price increase” the answer is: yes, a lot

Finding quick and reliable tests for Alzheimer’s is a key mission for science. And we have a new candidate

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Ahead of Alzheimer’s. It is a simple but difficult objective to achieve since the symptoms of this disease tend to appear when the disorder is advanced and has already caused important damage to our brain. A difficult objective but what It can help us treat the disease With greater efficacy, managing to delay the appearance of some of its symptoms such as cognitive deterioration. Maybe one day helps us cure it. In the blood. A group of researchers has tested a new blood test aimed at the early detection of Alzheimer’s disease. The test is based on a biomarker present in the blood, P-TAU217, which shows changes long before the appearance of symptoms in people with the disease. The study showed precision when detecting the disease greater than 90%. These results also did not depend on the age or gender of the participants, either on the existence of comorbidities or whether the test was carried out by specialists or primary care personnel. This marker can be measured with simple and cheap tools and the process is automatic, which can facilitate detection in various circumstances, democratizing the diagnosis of the disease. “This is an important step to bring simple blood tests for Alzheimer’s disease to health systems around the world,” said the team responsible for the essay in a press release. P-TAU217. Detection methods based on the P-TAU217 compound They are not exactly new. These types of tools are already implemented in the United States and it is expected that they will soon reach the rest of the world, says the team itself. The new method seeks to offer a simpler alternative to the available tools. The new study analyzed the precision of this New Test in the conditions in which it would be used, not only in specialized clinics but also in primary care. In three countries. The essay was carried out from 1,767 participants with cognitive symptoms distributed in three countries: Spain, Italy and Sweden. The details of the study were published In an article In the magazine Nature Medicine. The New Test included two cut points. One of them served to interpret the negative results: from this threshold the test rules out the presence of the disease. The second of the cut points serves to find the positive ones: this threshold shows the presence of the disease. This leaves, between one cut and another, a “gray zone” in which the results are inconcuing, however the use of a test with a single threshold slightly reduced the accuracy of the diagnostic tool. Above 90%. The study showed that the test achieved an accuracy between 92% and 94% when used in its two cuts mode. However, this precision fell to levels between 83% and 87% when only a cutting point was used and applied to more advanced ages. “When the method was tested in patient sides, the precision was between 92% and 94%,” NOëlle Warmenhoven explainedfirst signer of the study. “This is promising since this method will probably become one of the most used in clinical practice around the world.” In Xataka | We have a new “theory of all” to understand Alzheimer’s. Your key is in small granules Image | Kaboomps.com

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