If we want to increase human fertility, mice have something to tell us: fecal transplants

We knew that the bacteria that live in our intestine They are really positive and offer us extra protection against numerous threats from outside or even against Alzheimer’s. Now they have just added a new star function: they can help us improve our reproductive health. And all this with a simple fecal microbiota transplant. New evidence. This same month of March the magazine Nature has published an article that breaks with several scientific paradigms and demonstrates a bidirectional communication between the microbiome and women’s ovaries. The study here wanted to demonstrate that fecal microbiota transplant can completely remodel the behavior of the ovaries, reducing inflammation and even increasing reproductive success. But the most amazing thing about the experiment is not the ‘what’, but the ‘how’, since it has quite surprised the experimenters that the result has gone against what they expected. How is it possible? To understand this finding, we must first know the concept of ‘strobolome‘ which will give a lot to talk about in the coming years. In a simple way, it is a set of intestinal bacteria that are capable of metabolizing and modulating the level of estrogen, which is one of the main female sex hormones and closely related to reproduction. Until now, we knew that the microbiota played a role in almost every part of our body, ranging from digestion to our own mental health. But they wanted to go further, and in the past it was noted that they had already begun to explore how to transfer faeces from young mice to old ones, which would improve their ovarian reserve. But the best thing is that doing the opposite could accelerate the aging of the ovaries. The new study. Knowing this, this research team designed an experiment in which healthy adult mice were taken and given antibiotics to cleanse their intestinal flora. From here, they underwent a fecal microbiota transplant from mice in the ‘estropausal’ phase, which is like human menopause. What the researchers here were expecting is that if they were introduced to the microbiota of aged rats in reproductive decline, their ovaries would suffer damage. But the truth is that they were wrong. Results. The results here showed that adult females who received the “estropausal” microbiota not only did not worsen, but rather improved ovarian function and an increase in their fertility. Because? By thoroughly analyzing the organism of these ringworms, using sequencing of the genetic material of the ovaries, it was seen that the transplant had caused a massive remodeling of the ovarian transcriptome. That is, the way in which the genes in the ovaries were expressed had completely changed towards a “younger” profile. In addition, the analyzes revealed a drastic drop in the expression of genes linked to inflammation. The explanation that scientists are considering points directly to the strobolome, since it is possible that the microbiota of the stropausal mice, in its attempt to survive the natural drop in hormones of its original host, has developed brutal compensatory mechanisms. By transplanting these “surviving, super-optimized bacteria” into a young environment, they boosted the health of the recipient ovary. The future. Although in this case this effect has been seen in mouse animal modelsthe implications of this study may allow us to continue advancing treatments that can improve human reproductive health. The goal here is to be able to isolate what exactly are the specific microbial candidates or metabolites responsible for this improvement and in the future we could be talking about probiotic treatments or microbiome-based therapies to prolong fertility. Images | Kelly Sikkema CDC In Xataka | Drinking coffee in the morning has very positive consequences for someone unexpected in your body: the microbiota

the increase in abandoned oil tankers

Abandoning an oil tanker or other commercial vessel has gone from being something rare to becoming a dangerous trend: in 2025 alone there are 410 vessels registered, an abysmal difference compared to the 20 cases in 2016, according to data from the International Transport Workers Federation (ITF), a global trade union organization that tracks these incidents. What is causing this rebound? The first affected: the crew. An abandoned oil tanker does not only mean neglecting the vessel itself, but also more than 6,000 sailors abandoned to their fate, according to ITF global figures. The most affected are Indian sailors, with more than a thousand people affected representing the majority of the total. One case is that of Iván (not his real name), the chief deck officer of an oil tanker that has been abandoned for weeks outside the territorial waters of China, which recently declared for the BBC how this event has affected their health and the environment: “We had a shortage of meat, cereals, fish, basic things to survive.” And that’s not to mention the uncertainty of seeing the Chinese coast and not knowing if you’ll be able to set foot on it. The context: the ghost fleets. Over the last few months we have heard about “ghost ships” or “zombie ships”, that is, ships that legally barely exist, with owners hiding behind front companies. The objective is to operate outside the official financial and regulatory framework to evade sanctions through “prohibited” routes such as Iran, Russia or Venezuela. The Ukrainian War and the context of sanctions have created a B market for old ships that transport oil. The ideal candidates to become ghost banks are aging vessels, generally oil tankers that are around two decades old, a critical age at which the vessel is already headed for scrapping, which makes it easier for them to move into that clandestine scenario. Whoever buys it is not going to invest in long-term maintenance, he wants to pay it off quickly by transporting sanctioned crude oil. These types of boats lack complete insurance such as P&I Clubsso that in the event of any problem, the shipowner disappears before assuming repair or repatriation costs. The legal trap of rental flags. Here the “flags of convenience“, something like the tax haven of the seas. This is what happens when a shipowner registers his ship in a country other than his own to benefit from more lax regulations. There is a legal disconnection between the real ownership of the ship and the state that gives it the flag. And what does it have to do with abandoned oil tankers? According to the ITF82% of abandonments occur on ships that operate under flags of convenience. Among the states with flags of convenience are Panama, Liberia and the Marshall Islands, which represent 46.5% of all merchant ships. But there is one country that deserves a special mention: Gambia. In 2023 it went from having no ships to having 35 sailing under its flag, a record time to create that infrastructure organically. In addition to softer legislation, many of these countries outsource inspections to private organizations and lack sufficient technical personnel to verify it afterwards, such as notes the International Maritime Organization in several reports. Prisons and floating time bombs. Ivan’s is just one case, but what an example: The ship is carrying almost 750,000 barrels of Russian oil that has a nominal value of about 50 million dollars (42 million euros). He left the Russian Far East for China at the beginning of November 2025 and there he is, at the gates of his destination and unable to enter. It is so that the alarms go off due to the environmental risk posed by a possible spill from an abandoned ship without responsibility. Furthermore, the safety of the vessel is compromised, as human error accounts for more than 80% of maritime accidents and these sailors are not exactly at their best. Fortunately, the ITF took charge of the situation in December, providing payroll arrears up to this point, providing groceries and other essentials, and planning repatriation. It is not an isolated problem. The drastic increase in abandoned oil tankers represents not only a violation of international sanctions and regulations, but also a human drama and potential environmental disaster for which there would be no legal responsibility to cover it. Although it is true that there are interventions and approaches and that there are states putting pressure on those countries that are banners of flags of convenience like Gambia and achieving something in the attemptthe reality is that this is a global phenomenon that requires stricter international regulation, serve as an example India’s blacklistwhich included 86 foreign ships in a database for abandonment of sailors and violation of their rights. In Xataka | Fewer and fewer oil tankers are being scrapped, and there is only one reasonable explanation: Russia’s ghost fleet In Xataka | The ships of the oil “ghost fleet” turn off their GPS to avoid being detected. Malaysia is going to hunt them with drones Cover | Jack Dong

Valve has just announced a delay and price increase for the Steam Machine

Valve’s plans to revolutionize desktop video games face the reality of the component market. The company has confirmed the postponement of Steam Machine, Steam Frame and Steam Controller, initially planned for the first quarter of 2026, due to the global shortage of RAM and storage. The announcement comes accompanied by a warning: the initially announced prices will be revised upwards, which puts at risk the strategy of competing directly with traditional consoles. What we believed. The official presentation of Valve’s hardware took place in November 2025when the company simultaneously unveiled three devices aimed at expanding its ecosystem beyond the traditional PC: the Steam Machine console, the Steam Frame virtual reality headset, and a new iteration of the Steam Controller. At that time, information provided to media It targeted a launch in the first quarter of 2026. Our love broke. However, Valve has had to recalibrate its expectations. According to the statement, the company acknowledges that it hoped to announce definitive prices and specific release dates at this point, but circumstances in the component market have prevented this. “The limited availability and rising prices of these critical components mean we must review our exact shipping schedule and pricing,” they admit. A little later. The new time frame now extends to the first half of 2026, a deliberately vague formulation that contrasts with the initial precision. Valve emphasizes that it maintains its goal of distributing the three products within that period, but warns about the volatility of the scenario: they need to establish prices and dates that they can announce with confidence, aware of how quickly circumstances can change. The RAM crisis. The problem affects the entire technology industry. Memory manufacturers have experienced a unprecedented price increase: according to data from the component market, the cost of RAM modules has multiplied by three or even four from the beginning of 2026. This escalation responds to a strategic reorientation of the major producers such as SamsungSK Hynix and Micron, which prioritize the manufacture of high-performance memory for artificial intelligence servers, a segment that offers higher profit margins. It was seen coming. Already in November, when Valve presented its hardware, the warning signs were evident. By then, the company recognized that setting prices was complex because “the market is a little strange” and “memory prices are going up as we speak.” What seemed like temporary turbulence has been consolidated as a structural trend. It is a crisis that evokes the semiconductor shortage that shook the industry between 2020 and 2022, causing delays in the launch of consoles and widespread price increases in graphics cards. The current phenomenon presents, however, a peculiarity: it is not about interruptions in the supply chain, but rather a deliberate decision by manufacturers to redirect productive capacity towards the lucrative AI market, leaving the gaming industry in the background. What is known about the machine’s hardware. The Steam Machine, the star product of this trilogy, will be powered by an AMD processor, as confirmed by the semiconductor company’s CEO, Lisa Su, during the presentation of quarterly results: “From a product perspective, Valve is on track to begin shipping its AMD-powered Steam Machine early this year.” That statement, which sounded reassuring then, now takes on an ironic tone: the hardware is ready, but the economic context is not. During previous sessions with specialized media, the company indicated that the Steam Machine would be placed “close to the entry level of the PC space”, a formulation that suggested that it would compete directly with PlayStation 5 and Xbox Series X|S in terms of price, rather than with high-end PC configurations. This approach clashes head-on with the current reality of the components market: competing with consoles means achieving very tight margins in a closed ecosystem where Sony and Microsoft can assume initial losses. Valve lacks that flexibility, and the increase in memory and storage costs threatens to place its products in a price range that would distance them from the average consumer. In Xataka | Panic of a ridiculous death among RAM manufacturers: they fear that technology companies will “monopolize” and they are already putting controls

The minimum wage in Mexico has risen in January. This increase is not reaching everyone and is creating confusion

Spain is not the only one considering annual increases in your minimum wage. Starting January 1, the Mexican workers who earn the least will see their salaries increased with a new increase in minimum wage. However, some are beginning to notice that that increase is not reflected on your payroll and is generating some confusion. The trick is that the increase in the minimum wage which has been applied in Januarydoes not imply a general salary increase for all workers, but rather a minimum legal ceiling for salaries. What is the minimum wage and what is it for? As its name indicates, the minimum wage is the legal minimum amount that any company must pay its workers. In the case of Mexico, this minimum wage is established by Conasami (National Minimum Wage Commission) a decentralized body of the Mexican government that is responsible for updating it every year with the intention of protecting those who earn the least. However, the salary increase imposed by this body does not represent a percentage that must be applied to all salaries, but rather the minimum daily amount that employees must receive per day. According to the salary table prepared by Conasami, by 2026 the minimum wage will rise to 315.04 pesos per day in most of the country and 440.87 pesos per day in the Northern Border Free Zone. That implies an increase of 13% for the majority of the country, and 5% in the border area with the United States. Why doesn’t the increase reach everyone? The point of confusion among Mexican workers centers on the erroneous interpretation that this 13% and 5% increase is for salaries, when in reality it would only affect the lowest salaries that are within the legal minimums established in the Federal Labor Law. That is, if in January 2026, a worker continues to receive a salary of 278.80 pesos (419.88 pesos for the ZLFN), which was the minimum wage in 2025, his employer would be violating labor legislation. However, if an employee already earned more than 316 pesos, his or her salary does not have to have increased, since it exceeds (even if only slightly) the minimum limit established by the Federal Labor Law for 2026. Who should see their salary increased. There are three clear groups in which there is a legal obligation to increase the salary when the minimum increases. The first and most obvious, those employees who earn less than what is established by the new minimum wage. The second assumption is for those who were already earning exactly the minimum wage in 2025, since with the update they would be out of legality in 2026. Finally, there is a third group of employees to whom, due to the type of profession they practice, a different scale is applied and, therefore, their salaries must increase even when they already exceed the minimum wage. Specifically they are 60 professional categories that Conasami estimates that, due to their characteristics, they must have a minimum wage higher than that generally applied to other workers. When the salary is “higher” but does depend on the minimum. In Mexico, the minimum wage can also be applied as a reference indicator in contracts. That is, instead of indicating a specific salary, the employment contract indicates that the salary will be, for example, three times the current minimum wage or 350% of that minimum limit. In that case, since it is a reference variable, when the minimum wage rises, those wages will also rise in the same proportion according to what is stated in those contracts. Minimum wage vs. contractual salary. An important factor is to differentiate the minimum wage from the contractual wage. That is, the one that employees agree with the companies at the time of hiring. The first guarantees that no one will be able to charge less than the official figure established each year by the Commission. If an employment contract concluded a few years ago recognizes a salary that is currently below the minimum wage imposed in 2026, the minimum wage will prevail, since its objective is for employees to update their purchasing power. The salary that appears in the employment contract loses its validity. In that case, the salary increase is not a benefit that the company grants to the employee, but rather a legal obligation. On the other hand, if the salary indicated in the employment contract still remains above the minimum wage, the employer does not have to increase it, unless individual or collective increases are agreed upon with the workers. In that case, the increases are the result of voluntary negotiation by the company to improve the working conditions of its staff. In Xataka | Airbnb and digital nomads brought dollars to Mexico City: they have also brought the biggest housing crisis in years Image | Unsplash (Jesus Herrera, Arron Choi)

To take photos, I am clear about which phone I would buy right now. A high-end that does not increase too much in price

I have never been a big lover of photography because until a few years ago it had not really caught my attention. But I have been experimenting little by little and Nowadays on a mobile I prefer to prioritize this section before even the power. Although in some cases good power and good photography go hand in hand in the high range, there are times when this is not the case. Here, for color tastes. But me right now I don’t even remotely take advantage of the power that this type of mobile provides.so if I buy one right now I am clear that I would bet on the Google Pixel 10. The price could vary. We earn commission from these links A mobile phone with a great photographic section For many years I have played mobile games that were quite demanding. Currently, I only play one or two games very occasionally and they usually require quite low performance or power, as is the case of the Solitaire or, to a lesser extent, ‘Balatro‘. On the other hand, what I am taking advantage of right now is the photographic section of the Xiaomi 14T. I quite like to play with the options offered by the cameras signed by Leicaso it is clearer than water that the next mobile phone I would buy right now is Google’s. He Google Pixel 10like the rest of the brand’s models, has the particularity of having as a base the Google app. Yes, this can be adapted with the GCam in other mobile phones, but to this we must add excellent processing and a five-fold telephoto. The photographic section, focusing on the camera module, is made up of a 50 MP wide-angle sensor, a 13 MP ultra-wide angle sensor and a 10.8 MP telephoto sensor. It is also worth mentioning that it comes with Camera Coachwhich for those less versed in the subject may be attractive to receive recommendations through artificial intelligence. You may also be interested Spigen Ultra Hybrid MagFit Case for Google Pixel 10/10 Pro Compatible with Pixelsnap and MagSafe – Clear White The price could vary. We earn commission from these links Spigen Glas.tR EZ Fit Optik Camera Protector for Google Pixel 10, 2 Units, Transparent, Crystal Clear, Full Coverage, Installation Kit, 9H Hardness, Anti-Scratch The price could vary. We earn commission from these links Some of the links in this article are affiliated and may provide a benefit to Xataka. In case of non-availability, offers may vary. Images | Pepu RiccaGoogle In Xataka | The best mobile phones (2025), we have tested them and here are their analyzes In Xataka | The best quality-price mobiles (2025). Their analyzes and videos are here

Mathematicians have a simple way to increase the odds of winning the jackpot. Another thing is that it compensates

By more than try Abel Caballero, the beginning of Christmas (at least in Spain) is not marked by the lighting of the lights of Vigo, but by a much more consolidated tradition: the raffle of the Christmas Lottery. Every December 22, thousands of Spaniards tune in to TV, radio or press the ‘F5’ key on their computers every so often in the hope that the children of San Idelfonso sing your number. However, the probability of this happening is very low, as much as choosing a name at random from the census of a city and getting it right. The question is… Are there ways to expand that probability? 1 in 100,000. The Christmas Lottery generates excitement and makes thousands of Spaniards get out of bed on December 22 with a special tingle: the hope of seeing how their bank accounts suddenly add a handful more zeros. That is undeniable. Just as it is that, if we leave aside the illusion, the chances of our tenth(s) winning are very small. Lower case. The data speaks for itself and leaves little room for hope: in the hype 100,000 balls enter with numbers from 00000 to 99,999. Your number has the same exit options as the other 99,999, one 0.001% probability. Mathematics VS hope. “In these cases the probability is easy to calculate. Since all numbers are equally probable (there is a ball for each number), it would be calculated with Laplace’s rule: the number of favorable cases divided by the number of possible cases,” comments Miguel Ángel Morales, mathematician and author of the blog Gaussians for almost two decades. “Assuming that we have only one tenth, the probability of winning El Gordo would be 1 (there is only one Gordo) in 100,000 (since there are 100,000 numbers that enter the draw). That is, a probability of 0.00001.” What does that mean? Since talking about drums, tenths and statistics can be too abstract, Morales transfers the figures to something we are much more accustomed to: people. In this case we would exchange the tenths for cards and the drums for the municipal registry of a medium-sized city. “Let’s imagine that we have a DNI of someone from Santiago de Compostela and a list with the names of all its inhabitants (about 1,000,000),” reflects the professor. “The probability would be similar to the one we have of choosing one of those names at random and turning out to be the person with the DNI that we had at the beginning.” “If we talk about the total number of prizes, the way to calculate the probability would be the same: we would have to change the 1 (a single Gordo) for the number of prizes. Sticking to the main prizes, as there is a First, a Second, a Third, two Fourths and eight Fifths, the probability of getting a main prize with a single tenth would be 13 divided by 100000, 0.00013.” The big question. There is no Christmas without its Lottery and there is no draw in which it is not considered the same question: Do we have any way to increase our chances of success, however slim they may be? Is there any way to scratch a little more probability, even a few tenths? The answer is yes. And not. The starting data is what it is, but precisely for this reason our chances of being happy on the morning of December 22 increase as the number of different tenths that we have in our portfolio increases. More options? More tenths? “The only way to increase the probabilities is, effectively, to buy more tenths of different numbers,” confirms Morales. “If we have five of different numbers, the probability of winning the jackpot would be 5 in 100,000, which is 0.00005. There are no more mathematical ways to increase the probability of winning a prize.” That is, if what you want is to “maximize” your chances of success, you will have no choice but to put more eggs in the basket. Having more bills of the same number (even if you have a hunch) will only help you win more money in case that combination wins, it does not increase your options. “Speaking of refund, the probability would be one in ten if we have a single tenth. Obviously, buying more tenths with different endings would help us have a greater probability of getting that refund,” he adds. And Doña Manolita or the ‘tricks’? The Christmas Lottery is not only peculiar because of the Gordo, the stones and its symbolic value. It is also because in it statistics and pure hunch go hand in hand (just like in other games of chance). Hence there are people willing to endure long lines outside to buy a tenth at Doña Manolita or to always play the same number, perhaps a special number that coincides with your birthday or the date your child was born. Works? Do these ‘tricks’ improve our chances? Morales is very clear about whether the latter (repeating a number year after year) influences our fortunes: “No, it does not increase it. All draws are independent, which means that what comes out in a draw does not depend on what happened in the previous ones. They have no memory. Mathematically speaking, always playing the same number does not increase the probability of winning.” The administrations of “luck”. There is also no difference between buying a tenth at the corner fruit shop or doing it in administrations so famous like Doña Manolita, The Bruixa d’OrLotería Valdés or El Gato Negro. Manuel García, an expert in Statistics at the European University, was also very clear about this a few days ago in an interview with the diary ACE. “They give out more prizes because they sell more numbers, not because they are luckier. It’s a self-fulfilling prophecy effect. It’s very important because since it has that reputation (I don’t know how it originates) people usually go there to buy. They are the ones that … Read more

plans to increase production of the H200 in the face of an avalanche of orders, according to Reuters

NVIDIA once again finds itself in the center of the game. According to Reutersthe company analyzes increasing the production of its chip H200 after orders from China have exceeded what its current capacity can cover. But this time the result will not be decided in Washington, but in Beijing, where the government must authorize the entry of the hardware. The Chinese response will determine whether the window opened by the United States translates into real sales or remains a gesture caught between opposing interests. What has changed in Washington. The turnaround began in Washington on December 8, when Donald Trump announced that the United States would allow the H200 to be exported to commercial customers approved and validated by the Department of Commerce, with a 25% tax on each sale. The measure marked a turning point with respect to previous restrictions and introduced a more flexible control model: the US Government will supervise shipments from Taiwan, subject processors to a security review before authorizing their departure to China and apply the corresponding surcharge. NVIDIA celebrated the announcement as a balance that, according to its own statement, seeks to make national security compatible with commercial activity, while in the markets its shares rose around 2% in subsequent operations. Avalanche of orders. The signal that has led NVIDIA to consider increasing production is clear. According to the aforementioned agency, H200 orders from China already exceed the current manufacturing capacity of the chip. AND, as we pointed out last weektechnology groups such as Alibaba and ByteDance have contacted the company to explore volume purchases, aware that availability is very limited. NVIDIA has informed these clients that it is studying adding capacity, although without commitments or figures, in a context marked by scarcity and the priority that other more advanced generations have today. The interest in the H200 is also explained by its place in the NVIDIA catalog. It is the most powerful chip of the Hopper generation and a clearly superior alternative to the trimmed models designed for China, although it falls behind Blackwella generation with which, Trump explained, NVIDIA’s American customers are already moving forward. That position makes it an awkward balance: it’s not state-of-the-art, but it’s advanced enough to make a difference in training large-scale models. What China decides. Beijing is not limited to giving a yes or no. According to sources cited by Reuters, the internal debate revolves around how to allow access to H200 without weakening the momentum of its domestic semiconductor industry. The authorities are studying imposing specific conditions on each order and reviewing the final destination of the chips, in a context in which Manufacturers like Huawei or Cambricon continue to be priorities for the country’s industrial policy. NVIDIA H200 Capacity and bottlenecks. Increasing H200 production is not an immediate or easy decision. The chip is manufactured at TSMC using its 4nm process, an advanced capability that is hotly contested today. NVIDIA is prioritizing Blackwell production and preparing the transition to Rubinwhile competing with other large clients, such as Google, for space in the Taiwanese manufacturer’s most advanced lines. That context explains why the company has warned its customers of tight supply even if it ultimately decides to add capacity. National security and industrial pressure. The H200 debate goes beyond NVIDIA. In Washington, fear persists that the sale of advanced chips will contribute to strengthening China in sensitive areas, while the Administration itself has defended that completely cutting off access to American chips could reinforce the efforts of local manufacturers. The solution adopted by the Trump Administration seeks that balance, but keeps alive a controversy that conditions both exports and the real possibility of expanding production. With demand pressing and supply at a minimum, the outcome is now being played out in the offices of the Chinese regulator. If Beijing authorizes the purchases, NVIDIA will have to decide to what extent it can reallocate capacity without compromising its industrial priorities. If it doesn’t, the H200 will join the list of advanced chips caught between politics and strategy. In both scenarios, the episode confirms that access to hardware has become as determining a variable as the chip design itself. Images | NVIDIA + Photoshop In Xataka | Microsoft has reduced its ambition with AI. It has been realized that almost no one uses Copilot, they say in The Information

how much science believes our longevity will actually increase

Society is increasingly obsessed with living longer and longer and have an aesthetic that corresponds to a younger age. Right now there are many really eloquent projects to achieve practically immortalitybut this makes us wonder if our body has some kind of limit that cannot be exceeded. This is what science tries to elucidate. Nowadays, people who live more than one hundred years are something extraordinary, and we even see their centenary birthdays appear on the pages of the newspaper or on local television programs. But the question in this case is whether the new normal will be being able to live more than a century as something normal, and above all in good conditions. But the truth is that we are far from achieving this. Two concepts. The first thing to understand here is the difference that exists between the average life expectancy and maximum longevity. The first of these is growing spectacularly in the last century thanks to vaccines, hygiene, medications and better access to healthcare (although this reaches an older population, with its problems). But when we talk about maximum longevity we cannot say the same, since it is a much harder ceiling to crack. The obligatory question in this case is clear: where is our ceiling that we cannot break? Less than expected. There is now solid scientific evidence that suggests that human beings have a “factory” biological limit. Different studies, such as those published in Nature, they placed the natural human limit around 115 years. Although more recent and optimistic reviews, based on statistical modeling of the “supercentenarians” (people over 110 years old), extend that range up to 125 years. Therefore, we are not facing a scenario of immortality, but rather the age progression curve begins to stabilize at a specific point. And this is clearly a brake that biology itself is imposing on us, because our body has a very clear limit in its functioning. Prioritize well-being. Reaching the age of 120, but with very poor health, with many illnesses behind you or without being able to move, is not something at all attractive. That is why demographic projections for Europe They suggest that, by the year 2065, life expectancy will be between 87 and 93 years. This doesn’t sound like science fiction, and that’s precisely why it’s relevant. It is not about making quantum leaps through unproven gene therapies, but about the accumulation of medical and social improvements. The goal of modern longevity medicine is not for you to live 150 years connected to a machine, but to extend the “healthspan“, that is, the period of healthy life. We already know the ‘secret’. While we wait for drugs that reverse old age, science tells us that we already have the “technology” to maximize our lives and it has been used for decades in the so-called ‘Blue Zones’ of Okinawa as a standard. And it is precisely in this area that people It is capable of easily reaching 100 years without much problemand the question was obligatory: why here? We found the answer in studies carried out in this areait can be seen that the factors that influence being able to reach 100 years of life have nothing to do with transfusions of young plasma, blood cleansing or super-expensive therapies that promise miraculous results. Among the habits that follow we can find the following: Natural calorie restriction: They consume 10-15% fewer calories than an average Western adult. And we already know that this influences above all the generation of oxidative stress which is a great ‘poison’ for our body. The good carbohydrate diet: their diet is based on vegetables and complex carbohydrates such as sweet potatoes, with a very low animal protein intake. Youth biomarkers: the combination of diet and constant physical activity results in a lower incidence of chronic diseases. Less stress: another great poison for the body due to its involvement in cortisol levels. In Okinawa, community cohesion acts as a buffer for stress. The importance of habits. In this way, the scientific horizon for the next century does not promise immortality. It is likely that we will continue to see a trickle of individual records and exceptional cases of genetics that cause us to see people who far exceed the century of life. But for most humans, This is not something we get. (or at least with a good quality of life). The true longevity revolution in the 21st century will be to make reaching age 90 the norm and not the exception, applying what we already know works: moving, eating less (and better) and maintaining strong social ties. And above all, do not wait for a magic pill, as has been demonstrated by the habits of Japanese people who have achieved an effect that no gene therapy has achieved so far. Images | Ravi Patel In Xataka | Not all brain cells age at the same time: we have found a “hot spot” of aging

Some users will get rid of the increase of Xbox Game Pass Ultimate, according to The Verge

Last week the news jumped: Xbox Game Pass Ultimate rose price. And it was not a minor change, but orn 50% increase that placed the subscription at 26.99 euros per month in Spain. For some, it was an inevitable adjustment. For others, a jump too abrupt to justify it without further ado. But in the midst of the stir, there are important nuances. According to The VergeMicrosoft has begun to send emails to certain users of the European Union clarifying that this new price will not apply to all equally. At least, not for the moment. “At the moment, these increases will only affect the new purchases and not to your current subscription in the market where you reside, provided you have orn Automatic recurring plan“Says Microsoft.” If you decide to cancel your plan and buy it again, you will be charged the new current rate, “adds the company. The notice adds one more detail: if in your market there will be a price increase, these users will receive a notice at least 60 days in advance and may cancel or modify your plan. This condition, however, seems to be applied only to the markets where the people who received the message reside. For now there is no official confirmation about which countries are included in this exception, but The Verge mentions cases such as Ireland, Germany or Poland. In Xataka we have contacted Microsoft to know if Spain is part of that list and update as soon as we have an answer. In development. Images | Xbox | Capture (The Verge) In Xataka | Game Pass is already an unsustainable investment: more than 2,000 euros for each console generation and with nothing in property

Microsoft rises strongly the price of Xbox Game Pass Ultimate in Spain. The increase comes next to a renewal of plans

If you are an Xbox Game Pass user or you are thinking of subscribing to the Microsoft service, prepare for important changes. Adjustments have just come into force that do not go unnoticed, including a strong increase in the price of its most complete modality. Xbox Game Pass Ultimate now costs now 26.99 euros per month. It is a 50% increase compared to the 17.99 euros paid so far. It is not the first time that this plan increases its price: in July 2024 it had already gone from 14.99 to 17.99 euros per month. The justification. According to the company, Ultimate will give access to more than 400 titles worldwide, “including most of our partners who wish to continue bringing their future games to Xbox Game Pass.” In addition, the service will offer support for 1440p resolution and improvements in the bits rate on certain devices. How far the changes arrive. Microsoft has also reorganized the offer and says goodbye to the previous nomenclature. Xbox Game Pass Core is called Xbox Game Pass Essential, while the standard plan is transformed into Xbox Game Pass Premium. Game Pass Essential Game Pass Premium Game Pass Ultimate Game Pass for PC available games More than 50 More than 200 More than 400 “Hundreds of games” for PC Cloud streaming Yeah Includes own games Yeah Shorter waiting times Includes own games Yeah “With the best quality” With shorter waiting times Includes own games No available games day one No No, they join up to 12 months Yeah Yeah Online multiplayer Yeah Yeah Yeah Yeah Rewards points Up to 25,000 a year Up to 50,000 a year Up to 100,000 a year Up to 50,000 a year Advantages in games Yes, in ‘League of Legends’ and ‘Cod: Warzone’ Yes, in ‘League of Legends’ and ‘Cod: Warzone’ Yes, in ‘League of Legends’ and ‘Cod: Warzone’ Yes, in ‘League of Legends’ and ‘Cod: Warzone’ others – – EA play and ubisoft+ included EA play included price 8.99 euros 12.99 euros Free 14 -day test 26.99 euros 14.99 euros With Ultimate already on the table, it is time to see how they are premium and essential, what they include and how migration will apply to current subscribers. Premium, the intermediate option. With this plan you access more than 200 games both in console and PC, in addition to the possibility of playing in the cloud without limit, even with titles you already have in your library. • More than 200 games in console, PC and cloud • Access to classics such as Minecraft, Forza Horizon 5 or Grand Theft Auto V • New games published by Xbox available within a maximum period of 12 months (excluded Call of Duty) • Game in the unlimited cloud, also with own titles • Advantages In-Game in League of Legends, Call of Duty: Warzone or Rainbow Six Siege • Rewards of up to 50,000 points a year The ancient standard plan subscribers will automatically pass to Premium. It remains in the strip of 12.99 euros per month, that is, there is no price increase with respect to what we paid with the plan with the previous denomination. Essential, the new entrance door. With a more tight price, it offers the basics for those who want to try the service without great pretensions: a reduced catalog, cloud game and online multiplayer. • More than 50 games in console and PC • Access to prominent titles such as Hades, Stardew Valley or Cities: Skylines Remastered • Game in the unlimited cloud, including some games that you already have • Online multiplayer in console • Benefits in games like League of Legends and Call of Duty: Warzone • Rewards of up to 25,000 points a year We could say that they are designed for those who seek to start in Game Pass or just want access to a more limited set of games with basic advantages. Its price is encrypted at 8.99 euros per month. What about active plans. Restructuring does not force users to do anything: Microsoft will apply migration automatically. As we say, the old Core will pass to Essential, those of the standard plan will move to Premium and those who already pay Ultimate will continue in that modality. In development. Images | Xataka with Gemini 2.5 In Xataka | Saudi Arabia is not buying EA for video games. He is buying cultural influence in hundreds of millions of homes

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