Galapagos tomatoes are ‘evolving in reverse’. And that is spectacular news.

The Galapagos Islands They are the living laboratory of evolution. It was there that Charles Darwin observed the differences in finches that cemented his famous theory of natural selection and that laid new foundations for the evolution of the human species. Now, almost 200 years later, these islands are back in the news, but for a surprising reason: a species of wild tomato seems to be turning the evolutionary clock. But the most important thing of all is that this involution in vegetation opens the door for us to understand how small changes can give us a wide range of possibilities in human pharmacology. The discovery. A new study published in Nature Communications has discovered that, while evolution followed its “normal” course on the oldest islands of the archipelago, the tomatoes on the younger, more hostile islands have “devolved.” And they are actively recovering a chemical trait that their ancestors lost millions of years ago, something that doesn’t seem too logical. And it is not logical because we all have in mind that changes are always for the better to adapt to a specific environment. But these plants are giving us a completely different perspective than what Darwin saidalthough it has important applications especially in pharmacology. A chemical twist. The study of ‘involution’ focuses on the steroidal alkaloids (SGAs), powerful compounds that plants of the Solanaceae family (such as tomatoes, potatoes and eggplants) use as a natural defense. These compounds have a key characteristic: chirality. This means that a molecule can exist in two forms which are mirror images each other, as if it were our left and right hand, or even a reflection of ourselves in a mirror. The two ways are the following: The modern “tomato type”: mainly produces the 25S isomer. The ancestral “eggplant type”: produces the 25R isomer. In this way, the study is seeing that although years ago it was normal to produce 25R, it was later changed to producing 25S. Now, evolution is taking off again to return to the most ancient. Behind this is an enzyme called GAME8 that has dictated what type of chemical defense each plant produces. In fact, the researchers showed that by modifying just eight amino acids of the tomato GAME8 enzyme, they could stop it from producing its 25S compound and make exclusively the ancestral 25R. It is literally an evolutionary switch. Evolution in ‘reverse’. This is where the plot thickens. The researchers analyzed the Solanum cheesmaniaea wild tomato endemic to the Galapagos. And what they found challenges the idea of ​​linear evolution: On older islands, such as St. Kitts, tomatoes almost exclusively produce the ‘modern’ 25S isomer. On more modern islands like Isabela, tomatoes have changed and accumulate high levels of the ‘ancestral’ 25R isomer. It’s not that these plants were “left behind.” The data suggest that their immediate ancestors produced 25S, but the unique environmental pressures of younger islands have favored mutations in their enzyme. GAME8 that they have made it return to produce the ancestral compound 25R. It is a clear case of reverse evolution. Because. Younger islands are more arid and hostile environments, and science suggests that this ‘ancient’ chemical cocktail could offer better protection against pathogens or herbivores specific to that inhospitable environment, or even help the plant in different soil conditions. The important thing. Beyond being a botanical curiosity, chirality is a fundamental concept in pharmacy. One isomer of a drug may be therapeutic, while its mirror ‘twin’ may be harmless or, in infamous cases such as thalidomide, tragically toxic. Understanding how nature has managed to make a single enzyme (GAME8) change its product from 25S to 25R through a few mutations is a great advance for biotechnology. We could, in theory, use this knowledge to engineer crops with specific alkaloid profiles, creating more resistant plants or, conversely, eliminating anti-nutritional compounds. Images | Airplane CP In Xataka | The skull that changes everything: a million-year-old fossil suggests that ‘Homo sapiens’ did not come from Africa

The US pursues the AGI as if it were the Holy Grail. In China they are more pragmatic and are applying AI to plant tomatoes

The long AI career continues its course, and although it seemed that the United States had taken the lead, China has managed to recover the lost terrain and stand up to the Big Tech. The funny thing is that The approaches of these two countries are totally differentand that makes great losers and winners here. In short and long term. US for the AGI. The North American country has a very different strategy from that of China in regards to artificial intelligence. Large technology companies are investing billions of dollars in search of that holy grail called AGI (General artificial intelligence). China, more pragmatic. On the other, China, which has adopted a different and much more pagmatic strategy. Rather pursue great objectives that a priori are far from being achieved, the Chinese government, led by Xi Jinping, is prioritizing The development of AI practical applications that are above all efficient and have limited implementation and, if it can be, low. Promises, promises. The difference between both visions is huge but highlights the mentality with which both countries face their efforts. The US companies that work in the US believe that the AGI is close despite Some experts They are clear that The generative AI is not the way. The Manhattan Project of the IA. That seems to give equal to visionary theorists looking for that AGI, because according to them, this mile military advantage that can suppose. For certain sectors politicians in the US the development of an AGI It is comparable What the Manhattan project was and the construction of the atomic bomb during World War II. But as they explain Some expertsthat project was not the three years of work, but rather supported studies and research that had been running for three decades in an US that at that time looked in the long term. China wants to be useful today. That way of contemplating the career of AI contrasts with that of China. Its leader, Xi Jinping, has not shown special interest in AGI, and its approach is much more pragmatic: he seeks to focus AI on applications for practical purposes. That has led to the Models of the AI ​​developed in China are already taking advantage of everyday tasks. Practical applications. For example, they point out In The Wall Street Journalhttps: //www.wsj.com/tech/ai/china-hasthe qualification of access exams to high school, the improvement of weather forecasts, or assistance to agriculture with methods to optimize crop rotation. It should be noted that the US also uses AI in these areas, at least in the form of projects such as Google Weather Lab either Alphafold 3 For the development of medications with AI. Chinese government support. Although there are efforts by both countries for that practical approach, the difference here is that in China there is a very fortune government support. Beijing is investing significantly in that vision with a Investment fund of 8,400 million dollars To support new startups, and both local governments and Chinese state banks have launched their own investment programs. And open models. Another of the key points that differentiate both strategies is that of the closed and owner of the models of the large US companies and Open and open source vision of Chinese models. These open models allow to be downloaded and freely modified, and also reduce the cost of implementing this technology for companies that want to adapt it to their needs. The trade war conditions everything. It is also true that commercial restrictions imposed by the US condition the Chips development and AI software in China. That has caused the Asian giant to have adopted a curious tactic: to let the US assume the enormous costs of exploring new paths to develop AI, and then follow its steps as quickly as possible but without having to face those strong economic investments. Risk aversion. Although Xi Jinping may raise a strategy that the AGI pursues, experts say it will only do it when I see that you have enough guarantees of succeeding. Kendra Schaefer, from the trivium Chinese consultant, explained How the Communist Party does not want to be threatened by an AGI that condition its future. According to her, the Chinese government is “one of the most reluctant governments to the planet’s risk.” Outstanding image | Xataka with Midjourney In Xataka | China has declared the war on private school: why he predicted the prolific “tutorials”

In the mid -twentieth century the nuclear was fashionable. So someone created “atomic” tomatoes and cucumbers

The human being has from the dawn of agriculture trying to improve their crops. Before the arrival of advanced laboratory techniques such as CRISPR or the tools that the transgenics gave them, our species tested with a retahíla of various strategies to obtain larger fruits and vegetablestastier or more resistant. Some more successful than others. Some that bordered the demential. To the latter group belongs to the atomic horticulture, Atomic Gardening. The name of the technique speaks for itself. Atomic horticulture started from the idea of ​​bombarding radiation plantations. The objective of atomic horticulture, or at least the nominal objective of this, was to force mutations that improve the properties of food that were extracted from them. For this, the orchards were arranged in concentric circles, in whose center the radioactive material was located (Generally cobalt-60) capable of emitting gamma rays. The disposition implied that the successive circles received radiation dose that could vary significantly. The closest plants ended up burned by radiation and many nearby developed lethal problems such as tumors. The rest of the plants would receive more moderate doses that would introduce small mutations in their DNA. These mutations could be harmful or beneficial: the technique could Accelerate the natural process Of genetic modification, the selection, natural or human, would make the rest. The origin of this practice is found in the first years of the nuclear era, in the 1950s. Behind this initiative could find an association called The Atomic Gardening Societydedicated to promoting this striking practice. In An article Posted in 1962 the magazine Naturethis agrarian society was defined as “a scientific, educational and non -profit body, which carries out research in plants reproduction using radiative and chemically treated seeds and plants.” The different members of the association could exchange through this different seeds and the organization also served to record the different genetic variations introduced into the plants. The Atomic Gardening Society He also published his own magazine in which members could share their experiences and knowledge. We pointed out before the objective of this practice was to improve the qualities of plants and their fruits, make the most productive and resistant crops and their most nutritious or tasty crops. However behind this practice there was something else: marketing. The 50s was the era of initiative Atoms for peacein whose bosom the atomic gardens were born. This initiative intended to show that the energy responsible for devastation in Hiroshima and Nagasaki could also be used for economic improvement, in this case, agricultural improvement. Atomic horticulture in Spain Atomic horticulture was not an exclusive idea of ​​great nuclear powers such as the United States or the Soviet Union but also various countries from Europe to Japan developed their own gardens. Spain also had Your own atomic garden. The so -called Atomic Jarín of Alcalá is what remains of the Spanish tante in this nuclear agriculture, the then called El Encín Gamma Radiation Field. The origin of this experiment, which did not use Cobalt-60 but Cesio-137is in 1959, when Spain began to leave its isolationist period and could receive this radioactive isotope from US nuclear power plants for the exotic objective of building its own atomic garden not far from the capital. Today atomic horticulture is history. As we pointed at the beginning, today we had less quirky techniques to introduce mutations into plants. The transgenic foods, despite all the controversy they generate, have been accompanying us for decades. In fact, the development of the “scissors” of CRISPR genetic edition has given a new push to the genetic edition of organisms. This tool allows a control never seen before, notably facilitating The work of those looking for Improve the quality, quantity or resistance of crops. Atomic horticulture is history, but their results still endure. They do it in the form of variants of fruits, vegetables and even ornamental plants whose origin is in one of the most unique agricultural practices in the history of humanity. In Xataka | A perfect storm looms over Spanish olive oil: heat, pests and a problem of productive capacity Image | Google Maps / Catalan

Spain has filled Europe with excellent tomatoes that do not know anything. It’s time to step further

The story is known: last year, the reputed French socialist policy Ségolène Royal gave a television interview in BFM.TV in which I accused Spanish tomatoes of being “false bio”to “deceive the consumer” and come to say that they were “surable.” Government, agricultural associations and personalities Like Jose Andrés They went out in Tromba to defend the Spanish product. So and today, the controversy should be to ask ourselves if there is something to learn from all this. But let’s start with the obvious. Spanish tomatoes are excellent. For decades, in fact, Spain has been the international reference of this product, and doing so is not easy. Remember that tomato is the fruit and vegetable culture more valuable What world. Only in 2021 they were consumed in the world More than 189 million of metric tons and represents 31% of all the vegetables that occur in Europe. That is, there is a lot of money in the tomato and there are many countries behind that money. Spain would not have been for years One of the great exporters of tomatoes from the world, nor would it have conquered all European markets, without extremely high quality and standards. Well know in Almería that a small failure It takes you out of the market in a matter of days. The kings of tomato … commercial. In fact, if we go down to detail, Spain nails three main types of best -selling tomatoes internationally: the balls, the Saladette and the cocktail. Within these typologies, the varieties of the Spanish field continue to excel in color, size and useful life. The problem is not that. The problem has never been that. The problem is that we have given Europe (and the rest of the world) just what they wanted: colorful tomatoes, good size and easy to handle “post-recreational.” And we have done it at a good price. That is, we have given them the best possible commercial tomatoes. The problem is that these tomatoes do not know Tomate. And commercial tomatoes lost the taste. In 2017, a team of researchers from the University of Florida led by Harry Klee They analyzed 398 different varieties of tomatoes with the idea of ​​tracing the genetic bases of their organoleptic qualities. His conclusions were that, while the smell-for-the balance of fruits such as banana and strawberry depend on a single volatile compound (or very few), “the tomato needs about 25 different compounds to build its unmistakable organoleptic identity. “ The composition. That are dozens of amino acids, sugars and well -balanced volatile compounds. A chemical balance that on the way to find better colors, sizes and durability, became something very difficult to maintain. And that, in fact, it has not been maintained: it is a common place to say that the tomatoes no longer know tomato, but the investigation He supports it. According to Klee and his team, commercial varieties only have 13 of the 25 volatile compounds that give the smell of tomato. There is life beyond commercial varieties. Faced with these varieties of great views, productivity and durability, we have other types of tomatoes: what is called ‘Heirloom’ (of ‘inheritance’ or ‘family relic’). A tailor drawer to talk about local or regional varieties, with little circulation, whose development process has allowed them to maintain a well-balanced flavor. It is not a miracle. We talk about less productive tomatoes (the plant can ensure more sugar in each fruit) and that, being little resistant to post-harvest handling “, have shorter distribution chains that allow greater maturation in Mata. That is, their technical limitations play against their commercialization, but in favor of their flavor. As is obvious, Spain is full of tomatoes of this type. Not only Barbastro’s pink tomato or Tudela’s ugly, no. The list is endless: the Montgrí de Girona, the Cor de Bou, the Mutxamel of Alicante, the Galician monfortes, the Avoa de Osdo, the tomatoes of the Sierra de la Culebra, the black tomato safe, the Mallorcan Valldemassa and a long etc. . No one in their healthy judgment can bite a well -matured mutxamel and take seriously that Spanish tomatoes do not know anything. I don’t know if Ségolène Royal compared a Spanish commercial tomato with A French Heirloom variety or simply I was doing politicsbut it is true that beyond all The inaccuracies and tone outputsthere is something interesting about what we can reflect as a country. Spain and the tomatoes of the future. In 2022 and for the first time in history, Moroccan tomato sold more than Spanish. And not a little: sold 21.3%. Gradually, the United Kingdom and especially France have begun to replace Spanish tomatoes for those from the other side of the Strait. There are many reasons behind this, but few solutions. And, although Spain is still very strong in the rest of Europe and is opening a hole in the North American market, the ‘sorpasso’ is a warning to navigators. The regulatory advantage of belonging to the EU is getting rid And what we started to see is an agricultural giant with mud feet. And it’s time to take it seriously. We know that to continue being an international reference in the sector we will have to launch one of the “agricultural transformations” more important in history, the question is whether we take advantage of our competitive advantage to lead these changes or engage in an international war that We don’t seem like we can win. Image | Josephine Baran In Xataka | We have a problem with pesticides in agriculture. And a bigger one with the panic they generate In Xataka | To save Spanish wine, government and producers have come to a conclusion: you have to start starting vineyards *An earlier version of this article was published in February 2024

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