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A Spanish hospital has been responsible for taking the new step

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The ATP molecule, adenosine tryphosphate or adenosine trphosphate, It is fundamental For complex life on earth. This molecule is responsible for storing energy in cells and can now be key in a new task: end alopecia. A new study. A team of researchers from the San Carlos Clinical Hospital in Madrid has published a new work in which a treatment cell -based treatment and ATP molecule are studied. The team evaluated this technique in mice to reverse alopecia, and He did it successfully. Androgenic alopecia. The new technique seeks to try to reverse androgenic alopecia, the common baldness that affects a high proportion of the population. It is estimated that 80% of men and 40% of women experience this form of hair loss throughout their lives, according to the data provided by the team responsible for the new study. The team induced alopecia in mice through the administration of dihydrotestosterone molecule (DHT), a compound that the human body produces naturally and whose proliferation is associated with hair loss. A combined technique. The new technique to reverse alopecia combines the use of stem cells derived from adipose tissue with the ATP molecule. As explained by the team responsible for testing the mechanism, this combination is capable of stimulating hair regeneration by adding to the regenerative capacity of the cells the energy push of the molecule. “This synergy favors the recovery of the hair follicle, promoting hair growth,” explained in a press release Eduardo López Bran, work co -author. A first success. As detailed by the team, the technique managed to reverse induced alopecia in 100% of males and 90% of females treated totally or partially. In both males and females, total hair recovery occurred in 50% of cases; While in the rest of the successful cases (50% in males and 40% in females), the reversion was qualified as “intense.” The details of the study were published In an article In the magazine Stem Cell Research & Therapy. Continue with the trials. For now the trials have only been performed with animal models. This indicates that the way to confirm the effectiveness and safety of this human treatment is long and lacking any guarantee of success. Despite this, the results are “promising” for the team, so in the future we could see new essays, this time in people as participants. In Xataka | The industry wants us not to fall hair never again. And it is getting closer to getting it Image | Abraham Sánchez Martínez

Ozempic and blindness, we have been on the track of an extremely rare adverse effect for months. Now the AEMPS has taken a step forward

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A few days ago the The United Kingdom warned on an unexpected effect associated with the use of Ozempic and treatments based on the same principle, the phenomenon of Ozempic Babies. Now the Spanish Agency for Medicines and Health Products (AEMPS) has also issued a statement but this time as a consequence of a very different effect. Adverse reaction. This week the AEMPS, the agency in charge of ensuring that the drugs meet the required standards, has issued A statement To warn of a very uncommon ocular adverse reaction “associated with treatments based on the semaglutida, the active compound of drugs such as Ozempic, Rybelsus or Wegovy. The notice occurs after the Committee for the Risk Assessment in Pharmacovigilance (PRAC) of the European Medication Agency (EMA) reviewed the risk of developing an ocular condition called Niana, which can cause loss of sudden vision. While the agency affects that the frequency of appearance of this type of eye problems is “very low”, it recommends that a sudden loss of vision is carried out an ophthanmological examination for Evaluate the possibility to interrupt the treatment. Noiana. Noiana is an acronym that refers to calls Previous ischemic optical neuropathiesNaion in English. These ailments are caused For the infarction of the optic nerve head. In other words, blood does not reach this eye region and a loss of vision occurs, which is typically fast but painless. It is an unknown and infrequent disease, not only in the context of those who follow a trailer treatment: its prevalence in the general population is approximately 10 cases per 100,000 inhabitants. A year on track. A year agoa study I found indications of the relationship between the treatments of Semaglutida and Niana. Indications such as those that gave rise to the evaluation by the Pract. The Committee reviewed clinical and preclinical essay data together with suspicion of adverse reactions, explains the AEMPS. This work resulted in the conclusion that trailer treatment can be associated with a risk of developing this disorder but indicate that with a very low frequency. The AEMPS speaks of “an increase in the risk of developing Niana of approximately double compared to people not exposed to this treatment. This corresponds to an additional case of NOIANA for every 10,000 patients treated with semagglutida for a year.” And what about the “other ozempic”? The AEMPS statement focuses on the drug -based drugs such as Ozempic, Rybelsus and Wegovy but does not indicate whether similar effects have been detected on similar treatments such as those based on the tirzepatida, such as Zepbound and Mounjaro. A medication with side effects. Like any drug, the semaglutida has a series of Contraindications and side effects. It should be remembered in this sense that the success of drugs such as Ozempic began when it was observed that this treatment against diabetes made those who followed it lost weight. In Xataka | “Ozempic face”, “Ozempic language” and “Ozempic teeth”: the other very visible effect of consuming the medicine to lose weight Image | Chemist4u / Amanda Dalbjörn

The European Union takes another step to make it legal to charge us for hand luggage

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It is just one more step but it is very relevant if we take into account the battle that Government and Ryanair are fighting in Spain for this reason. Europe has taken another step for airlines to charge for hand luggage through a modification in the regulations to which travelers accept when they fly inside the European Union. And it is not the only relevant change. What has been approved? The European Union Council, formed in this case by the Ministers of Transportation of the Member Countries, has voted in favor of modifying the regulations with which the airlines have to comply within the European Union. The text is about the collection of the hand suitcase but also compensation in case of delay. According to the Information sent by the Council of Europeit is about defining better “with lighter and more direct rules” the rules to which passengers have to submit. And they emphasize that “they will bring more than 30 new rights to aerial passengers, applicable from the moment they buy the ticket, until they reach their destination, and in some cases even beyond. It is a historical milestone, since an agreement could not have been reached in the last 12 years.” Are all countries agree? No, the proposed text has been approved with the opposite votes of Spain Germany, Portugal and Slovenia. Austria and Estonia have refrained. In eldiario.es They point out that the meeting has extended much more than expected since there was no consensus on some points such as the times that must be overcome before compensating passengers. Click on the image to go to the original post Why does Spain complain? Spain has voted against the proposition because, According to Pablo BustinduyMinister of Consumption, “the Council has adopted a new regulation for aerial passengers that ends with the free of hand luggage that enters the cabin and reduces the right to claim for the delays of airlines.” The new text specifies that “additional rates applied by the transport of billed and not invoiced luggage” can be charged. That “not invoiced” is the key because it reinforces Ryanair’s thesis that there are no maximum required measures in which the size of the handbag is specified and, therefore, they will have a totally free way to maintain their current policy. From the government they point out that it is a mistake and that the measure has been promoted by “the airline lobby.” And Bustinduy emphasizes: “This new text confirms what we already knew: to charge for the hand luggage that enters the cabin or for the companion seat of a dependent person is illegal with the current legislation. That is why airlines have pressed both to legitimize this abusive practice with a new regulation” Not just luggage. In addition to hand luggage, the new text opens a new path for the right of passenger rights in case of delay. If the text is maintained until its final approval, the times that must pass before compensation will also be changed that, until now, was applied when the delay was greater than three hours. So, You want to approve new conditions: Trips of less than 3,500 km and trips within the EU: Compensation for delays of more than 4 hours (€ 300) Trips of more than 3,500 km: Compensation for delays of more than 6 hours (€ 500) Why is it relevant? The Government and Ryanair maintain an intense dispute in Spain. Ryanair only allows Free access to a lump of a maximum of 40x20x25 cm. That barely leaves space for a brief backpack and There are those who are doing business with it. For the Government, this way of acting is illegal because they ensure that it does not meet the minimum taxes by the European Union that talks about companies are obliged to allow the entry of “essential” luggage. This led the government to impose a fine that added 179 million euros to five airlines (Ryanair, Vueling, Easyjet, Norwegian and Volotea). Ryanair, the most punished, took a fine of more than 107 million euros. However, Justice has not shown preference Clara for any of the actors. In Spain, some courts have failed In favor of the user When it comes to claiming the money charged by the hand suitcase but others have proved the right To the Irish company. The Government-Ryanair battle. From the application of the fine, Ryanair and the government live an intense battle that has left us all kinds of scenarios: Remember that Ryanair is the company that greater volume of flights has in Spain And, therefore, its departure from some regional airports has seriously injured the activity that moved there, Like Valladolid’s. Is everything said? No, the text now has to pass the European Parliament Filter and it remains to be seen to what extent there is consensus. The change in the European Union Council has been approved by little (more than 15 countries that represent more than 65% of the population) and explain in eldiario.es that there have been differences when approved the increase in the necessary times before compensating passengers due to delays, this being the most thorny point. Photo | Niels Baars and Anastasiia Nelen In Xataka | Ryanair’s CEO is about to pocket 100 million euros. His merit: Make shareholders join him

Xiaomi surprised the world with his own mobile chip. The next step is to replicate this success in your electric car

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Xiaomi creating its own chips by the hand of TSMC It is something that we did not see in 2025 in which China’s greatest obsession is to boost 100% national technology. The company, in a movement to reduce dependence with Qualcomm and MediaTek Without breaking the ties that still tied to the United States, he presented his Xring 01. A chip capable of competing with the best in the market, thanks to both TSMC technology and its innovative design. The company has confirmed to be locking in its own chip for its future electric cars. It is one of the last pieces that the company needs to close the circle and not depend on companies such as NVIDIA or Qualcomm. The beginning of an era. Xring 01 is a before and after for Xiaomi. It is the first time that it manages to design a processor at the height of the best in the market, improving proposals such as the Qualcomm Snapdragon 8 Elite. Most of this TSMC baby success, who has manufactured this hand processor with Xiaomi. But its architecture is peculiar: it is the only high -end processor with a design composed of ten nuclei, and a distribution of workloads much more efficient than most current processors. Three chips, at least. Xring is the mobile processor, the Xring T1 It is the chip for watches, and Xiaomi has confirmed being working on a third processor for electric cars. The recent launch of your SUV, the Yu7came from the hand of Nvidia and Qualcomm, something that could change completely in the next generation of vehicles. Why there is a Qualcomm chip in the SU7. If you wonder what paint a Nvidia chip and a Qualcomm Snapdragon 8 Gen 3 In Xiaomi cars the answer is easy: electric cars, today, They are computers with wheels. Yu7 is one of the cars with the largest infotainment system in the world: one in which the windshield is a giant screen. Qualcomm Snapdragon 8 Gen 3 is responsible for moving HyperosXiaomi’s own software platform. Why there is a nvidia chip in Yu7. The central screen is just a small example of the computing capacity that an electric car needs. Assisted driving systems, Lidar data processing, radars and cameras, are in charge of the Autonomous Driving Platform Nvidia Drive Agx Thor. This software solution allows to manage high work loads with maximum energy efficiency, and is currently the most capable in terms of computing aboard a vehicle. A discreet approach. Xiaomi has not revealed data about whether you are preparing an adaptation of the Xring 01 to electric cars or if the goal is more ambitious and seeks to create its own complete hardware platform. The company has TSMC as an ally, but the design runs on its side. Competing to lead on platforms for new mobility is the next step for a Xiaomi that aspires to conquer almost all of the technological product categories. There Huawei has special advantage with Your Driveone platformone that gives life to Chinese vehicles like the Luxeed S7 or Aito’s latest proposals, such as the M5 and M7. The limitations. The United States Department of Commerce has tried to advise China, urging its national EDA software companies (electronic design automation software) to stop selling your products to your rivals. This software is key to the development of new lithographic processes, and one of the keys to lead the next generation of 2 Nm. Consequently, giants such as Xiaomi will have it complicated to continue improving the design of their chips. As much as TSMC is the one who manufactures them, falls into their hands to design their architecture. The current competitiveness of this chip resides largely in Your 3nm nodewhile China struggles to achieve ability to Manufacture 5 Nm national chips. There is a strong national movement in China to overcome this limitation and boost an EDA industry within the country. It is something that will end up happening, although not in the immediate future. Xiaomi’s great opportunity. Shanghai Xuanjie Technologies, the Xiaomi chips design subsidiary led by former Qualcomm and Ex Unisoc, is an important threat to the United States, with and without TSMC within the equation. The division has shown that, with the necessary tools, the design quality in Xiaomi semiconductors is up to the best. And there are the keys. How much will take advantage of that they can still collaborate with TSMC, and how much of a Xiaomi preparing its complete independence from the United States and seeking to be as competitive as Huawei on platforms for the car of the future. Image | Xiaomi In Xataka | An unexpected war has opened in China: Byd, Catl and Huawei fight for having the final electric car charger

In WhatsApp soon you can have a username. It’s just one more step in its ambition to become a surface

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Historically WhatsApp has been completely linked to each user’s mobile phone number. This identifier was the basis of its operation, and for example you needed it to create an account, log in and connect with your contact list. The phone number was absolutely essential, but will soon stop being in a network with More than 2,000 million users. WhatsApp had been in it for some time. It has been talking about how WhatsApp is preparing for user name support. In May 2023, certain details appeared on this option in a beta version of WhatsApp, but these changes never crystallized. Telegram supports this option For yearsFor example. Soon we will have that option. A preliminary version, WhatsApp Beta 25.17.10.70 for iOS, It has allowed discovering How will the interface be to choose a username to protect the privacy of the phone number. Although that does not necessarily mean that WhatsApp is going to implement the change definitely, it is a clear indication that the option could come. Not only that: it is expected to do it soon, before it ends 2025. Great advantages. This change raises various clear advantages that will make WhatsApp earn integers in several areas: Flexibility and customization of the service: because that will allow us to associate our name or alias like the ones we use on Twitter. Nothing to remember or point numbers. These user names also facilitate that we share that username with other people and that we better memorize those user accounts. Finding a person – or that she finds us – will be much easier. Account synchronization: to be able to use it on multiple devices will also be easier and more powerful with this system, and although WhatsApp has the traditional link -based bonding system QR codes, this type of characteristic would probably make to use WhatsApp on other devices apart from the mobile could be easier. Goodbye to geographical barriers: another important advantage, since once again when not depending on mobile number, communication with users from other countries, with different telephone numbers by national and local prefixes, is simplified. But above all, privacy. However, the true advantage of this movement is that of what will contribute to the privacy of users. With user names we can communicate with other people without the need for Share our phone number. This is very striking not to establish conversations with acquaintances, but to do it with people with whom we do it occasionally but that we would prefer that I could not access our phone number. It is also a very interesting way to prevent our number from falling into the wrong hands, such as fraudulent and spam accounts. This is the preliminary user interface of that user name request Be careful, user names will have rules. Already The rules have been revealed that we will have to meet users to use this system and ask for a “username”: They must have between 3 and 30 characters They cannot coincide with a username that already exists They can’t start with ‘www’ It is necessary to include at least one letter when creating them They can only include AZ letters, numbers 0 to 9, points and low scripts They cannot end with a domain (.com, .net, etc) They cannot start or end with a point (.) Nor have two points in a row Challenges for WhatsApp. Implementing this change after so many years also implies taking into account certain risks. Fragmentation: The current system based on telephone numbers is simple and universal, and user names can fragment the experience and generate confusion. Safety and supplantation: If user name authentication is disconnected from the number, WhatsApp must implement robust verification and recovery systems. Multiple identities: Those user names must be linked to the phone number, but it will be interesting to check how WhatsApp solves the problem of potential multiple identities, in addition to interoperability with other target services. WhatsApp’s triumph was simplicity. There is another important debate in this regard. For years one of WhatsApp hits has been to be a simple application and that solved a clear problem: that you could chat with your contacts, without more. In recent years we have seen how the application has been adding news such as States (Stories style), Channelsthe paymentsthe communities or integration with Other services of finish. More recently, of course, Goal AI. Do we need a overrapp? It is as if WhatsApp would like to become that overcomppp with which we do not need much more, but along the way the complexity of the messaging app has been increasing. It is true that the competitive pressure imposed by rivals such as Telegram or Signal causes them to be forced to move card, but in those movements there is a clear argument: that of monetization. The more functions and the more time we spend in the app, the more business opportunities there is a goal. Image | Rawpixel In Xataka | After 15 years of waiting, goal has finally done homework: WhatsApp for iPad has just launched

The EU is one step away from vetoing it in its great tenders, according to Reuters

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The Chinese market of Medical devices Live an accelerated expansion. According to a report published by Cambridge Networkit is expected to reach a value of 210,000 million dollars in 2025, promoted by a combination of internal factors and political ambition. The aging of the population and a state commitment determined by innovation have turned this sector into a national priority for Beijing. The strategy is clear: to bet on leading technologies and reduce the dependence of the foreigner. Investments have concentrated in fields such as artificial intelligence (AI) for image diagnosis, devices connected by IoT, robotic surgery or the use of advanced materials. All this under the umbrella of the program ‘Made in China 2025‘, which establishes precise objectives of national production in key areas of health. In that framework, China seeks In 2025 at least 70 % of high -end medical devices used in hospitals are local manufacturing. In strategic components, the objective rises to 85 %. And in the case of regional level hospitals, some guidelines already demanded to reach 50 % of Chinese products in 2020. According to Bloombergthis turn has had an immediate effect on trade. The European Commission states that China went from having a deficit of 1,300 million euros in medical devices in 2019 to a surplus of 5,200 million just a year later. EU’s response On Monday, June 2, the Member States of the European Union supported the commission’s proposal for RStringing access of Chinese manufacturers to public contracts of medical devices valued at more than five million euros, as Reuters saidBloombergand SCMPciting diplomatic sources and people familiar with the matter. It should be noted that the commission has not yet made the official resolution public. The measure is based on a legislation approved in 2022: the international public procurement instrument or IPI (for its acronym in English). This instrument allows Brussels to impose penalties to companies from countries where a lack of reciprocity has been tested. The sanctions can range from adjustments in the bidding scores to the direct exclusion of public competitions. According to the aforementioned Hongkonese newspaperthe measure could be applied in Question of weeksonce receives the final approval of the European commissioners. The current draft raises a duration of up to five years for these restrictions, although for now the final text has not been published. According to IPI standards, the measures must be proportional and allow exceptions case by case, at the request of the affected companies. The decision dates back to an investigation launched by the European Commission in April 2024. After a period of consultations without agreement, Brussels published in January 2025 a conclusive report: 87 % of public tenders analyzed in China contained explicit or implicit restrictions to foreign devices. In many cases, technical criteria were required that could only comply with local suppliers, or there were low prices that were unfeasible for business -oriented companies. The most affected sectors were the devices for otolaryngology (ENT), the general diagnosis and the diagnostic image. The commission also detected direct prohibitions to imported products in a growing number of competitions between 2022 and 2024. According to Bloomberg and Reuters, China did not propose any corrective measure during the consultation process. Brussels argues that the lack of access just to the Chinese market, combined with the privileges enjoyed by Chinese companies in Europe, justifies the activation of the IPI. Images | Arseny Togulev | Marcel Scholte | Arthur Wang In Xataka | Nvidia chips had always been a US negotiating weapon in their commercial war with China. Until today

Digi has installed its first 5G antenna in Palencia. It is a giant step to become a third operator in Spain

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Digi is not just a Giant in quality-quality. He is an aspiring to third operator from Spain and Your first 5G antennalocated in Palencia is the best proof of how it is heating the way to achieve its goal. Digi was born like A little OMV Romanian and has ended up being The fourth operator in Spain. The installation of This first antenna It is a milestone that goes beyond the technical. It is the sample of how it is becoming a giant capable of looking at the operators that, to date, seemed untouchable. The agreement with Telefónica. One of the keys to Digi finishes killing the perception of virtual mobile operator (OMV) that you could have about it has to do with its according to Telefónicaone that covers both national roaming services and Ran Sharing (radio access network). DIGI will continue to use coverage and infrastucure Shared with Movistar For another 16 years, although one of the keys is what this operator allows to access one of the fastest and most efficient 5G networks in the market. Mutualization of the spectrum. This strange term is understood so simple, based on the fact that the key to win in 5G is to have the best possible connectivity to networks 5G SA (The “real” 5g, the fastest and most latency). This 5G Eral works in the spectrum of 3.6 GHz. Digi had 20 MHz in this bandinsufficient to offer a competitive 5G, and Movistar with 100 MHz. Thanks to the mutualization of the spectrum, both Ópedoras have access to a total of 120 MHz shared, something that allows theoretical speeds of 2.2 Gbps and a reduced latency of 8 and 12 ms. Shared heart, own soul. Digi shares part of Movistar’s physical network, and has access to both its spectrum and its antennas. But the company completely manages its traffic, has its own infrastructure, and its first 5G antenna in Palencia is proof of this: there are areas in which it is capable of offering connectivity without intermediaries. The use of its own antennas allows Digi to release part of the traffic that depended on Movistar antennas, giving preference to its customers with their own antenna, and releasing Telefónica. Sweeping in Spain. Digi’s figures are applause. In 2022 he managed to with 60% of total portability In Spain, and at the end of 2024 it ended up winning almost one million lines. It is currently the fourth operator (CNMC itself catalogs it as such, outside the OMV), with a market share that touches 10%. It is still far from 19% of Vodafone, 26% of Movistar and 41% of Masorange, but the figure is spectacular for an operator who, until just a few days ago, did not have a single antenna of his own. The price strategy. Digi works what we like most in Spain: the quality-quality. Its product portfolio Fight for the most adjusted pricewith especially aggressive offers in unlimited lines. Do not neglect, despite this, additional services such as television centered on the LaLiga footballor cloud storage. Where does Digi look. Digi wants to enter the top 3 of operators in Spain. As you collect Xataka mobileif it maintains the current growth rate, it is an objective that will achieve in the short term: in 2026 it will become the third operator in terms of fiber lines. It is not such a simple challenge in regards to mobile lines, where distances regarding large operators remain broad. On the other hand, both Masorange and Vodafone are in loss of lines, with an especially unavailable situation for this last operator. Image | Digi In Xataka | Avoid surprises when hiring digi: advantages and disadvantages that should be known

Internet access democratized knowledge you were rich or poor. AI is destroying that conquest step by step

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$ 250 per month for using the most advanced AI. That is The figure that Google has put. Six months ago, OpenAi set his in 200. A few days ago Anthropic expanded Claude’s few limits with another 200. In any case It’s not just about paying for technology. It’s about buying power. And, therefore, to mark distances. Until recently, to talk about ia was talking about universal access. The free chatgpt or gemini versions were far from their older sisters, yes, but allowed to try, learn, benefit from their abilities even if it was a bit. Today that has changed. The powerful version is no longer available to everyone. It has been encapsulated after a monthly three -digit subscription that does not even start by ‘1’. It is the beginning of a new gap: Not between those who use AI and those who do not, but between those who can automate their tasks, think with help, execute complex flows … and those who do not. What Google or Openai offers is not just a better chatbot. Is an operating system of intellectual work. An assistant who not only responds, but understands the context, recalls, acts, generates, automates. Tools like Deep Research (OpenAI) or Project Mariner (Google) represent the decisive step towards Autonomous agents. They execute tasks that previously occupied days of human work. And in many cases they do better. With that, productivity is redefined. But inequality is also redefined. The question It is not only what this technology can do, but who can afford it. Because we don’t talk about a luxury. We talk about a tool that multiplies the performance of those who use it. An invisible advantage but that impacts everything: from the quality of work to the speed with which objectives are achieved. Who accesss these models lives in another learning curve, in another economy of results. Who cannot pay them, is trapped in a slower, less capable, more limited version of himself. This has a clear echo in history: the machinery of the industrial revolution also multiplied productivity … but at first only for those who could afford it. The same goes for now. The advanced AI begins to consolidate as an elite infrastructure. As if at the beginning of the Internet century, they were only available for those who paid $ 3,000 a year. And that changes the knowledge map. Because These tools not only report: they model how you learn, how it is decided, how it competes. Its effect is not immediate or visible, but cumulative. Day after day, those who access them will work with less friction, to make better decisions, to delegate more tasks, to generate more and better content. The others only observe, as much with access to the good, but not maybe. And they lag behind. The future is already priced. In Xataka | Google has become the most leading company at night. And the main winner is Android Outstanding image | Xataka with Mockuuuups Studio, Openai

OpenAi plans a future IPO. It is the definitive step to become a profit company

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Openai and Microsoft are renegotiating The terms of your non-dilio. The artificial intelligence startup recently announced an important change in its restructuring plans, and one of the objectives is that of a potential outlet. To the rhythm they are spending moneybetter that they complete that transition. Profit of profit. Last week OpenAi left his original restructuring plans. Its complex structure makes the “commercial” organization, which we know as OpenAI, is controlled by the non-profit organization (Non-Profit), OpenAi, Inc. Altman’s intention was to completely separate himself from the latter and become a company with profit (“for-profit”) traditional. Money and social good. However, They will become a public benefit corporation controlled by the non -profit organization. This type of entity not only seeks to obtain benefit, but also seeks social good. It is the same model that rivals such as Anthropic or XAI have adopted, and will allow OpenAi to offer their investors a business participation in exchange for their investments. And open the doors to an IPO.. Another of the key elements of the restructuring is that it will allow OpenAI as a public benefit corporation to opt for a public offer of actions to go over. That opens the definitive possibility to obtain funds: sell company participations such as any other company quoted in indexes such as Nasdaq. Microsoft Renegocia. Those renewed Openai intentions have caused them to now maintain a renegotiation of the terms of the alliance with Microsoft. The company of Satya Nadella has invested about 13,000 million dollars in Openai – part of them, in the form of resources to train their models – and OpenAi’s plans offer an opportunity to reach new agreements. More access to chatgpt. According to Financial TimesMicrosoft is willing to give part of its participation in that new corporation with OpenAi for profit in exchange for accessing its models and technology beyond 2030. The current agreement ends at that time and covers the access that Microsoft has to Openai’s intellectual property, in addition to a commission for the income that the company obtains for its commercial products, such as Chatgpt Plus. OpenAi is already giant. In FT they reveal that Openai is valued right now at 260,000 million dollars. However, the recent Softbank investment of 40,000 million dollars in Openai has caused that according to their own responsible Its valuation is 300,000 million dollarsas well as Coca-Cola. The IPO can further shoot its assessment, which is already colossal, thanks to its projection and popularity. But this moment is delicate. Analysts agree that Openai needs to complete that transformation to an entity with profit. If not, I would see future financing rounds committed, especially since companies that bet on OpenAi do it logically with the hope of recovering their investment with juicy benefits. They keep burning money. Meanwhile, in Openai they continue to burn money as if there were no tomorrow to train their generative models. The recent investment round led by SoftBank allows you to continue having a maneuvering room, but in the company they make it clear that they do not expect to have benefits until 2029. New member of the Big Techa group sight. By then, yes, its agricultural models and new products promise to make income of up to $ 125 billion, According to The Information. The step to a “For-Profit” structure is intended to endure until then and continue to have access to new funds in the future. It is a risky commitment, but one that can do well can make it a new full rule Big Tech. Image | Microsoft In Xataka | Silicon Valley has an obsession with “Todismo”: they begin by dominating a sector and then wanting to dominate them all

We are one step closer to converting pancreatic islet transplants into a functional therapy against type 1 diabetes

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The incidence of Type 1 diabetes It is less than that of its “sister”, but the World Health Organization esteem that more than 64 million people suffer only in Europe. In Spain, the number of cases exceeds 166,000 according to estimates of the National Health System. A new path. A study led by researchers from the University of Leiden has presented a new production method of endocrine cell groupings for transplantation. This tool could help us advance in this type of treatments against type 1 diabetes. Pancreatic islets. The work focuses on the pancreatic islet transplant. These islets are “groupings” of endocrine cells, hormone producing cells. Type 1 diabetes is triggered when our own immune system attacks pancreatic beta cells, insulin producing cells. The problem of transplanting these islets is to obtain them. An option is to obtain them from deceased donors, but this limits their availability. Another option is to “cultivate them” in laboratory from induced pluripotent stem cells. Easier to say than to do. However, there is a problem to solve, and these stem cells can differentiate themselves in the endocrine cells we are looking for, but they can also differentiate in other cells. “This is a problem because if you want to generate a reliable and safe product we need to be very pure, and that it does not vary in composition or purity from one lot to another,” explained to Sinc Adrián Villalba, an immunologist who works precisely in the development of this type of islets. A new method. In the new work, the team raises a new mechanism that facilitates the process of purifying unwanted cells without harming the integrity of the islets to be transplanted. The mechanism is based on density gradient centrifugation, used to enrich endocrine cell clusters and reduce the number of unwanted cells. The team tested their method successfully in mice. They observed that the transplanted islets remained viable for a period of six months. The details of the study were published In an article In the magazine Translational Medicine Science. A future still distant. Animals in animals are a key step, but it remains to be determined to what extent we can replicate the success of these first experiments in human cells. The success achieved so much in alive as In vitrothey point to optimism for now, but there is still time until we can see this progress turned into therapy. The team stands out in your work that this is a “fast” and “scalable method to large volumes of cells.” A method that can also be applied to cellular “manufacturing.” They also indicate the possibility of applying this method to contribute to the creation of new and improved cells based on cells in regenerative medicine, “beyond the field of islets (stem cells).” In Xataka | The 42,000 punctures of Elizabeth Hughes and the miraculous discovery of insulin Image | ISENS USA / Jakob Suckale

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