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Generic medications have been trying to site Ozempic for years. And now they have found a shortcut in Canada

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Something strange has happened with the patent that protects Ozempic In Canada. By mistake or by strategic decision, Novo Nordisk, the company responsible for developing the semaglutida, the compound on which the popular drug is based has been without paying the maintenance rates of this patent. An error of millions. The surprise jumped a few days ago. The chemist and expert disseminator in Pharmaceutical Industry Derek Lowe indicated Through an article in Science that the Danish pharmaceutical 370 dollars Canadians annual) that protects the compound on which drugs such as Ozempic and Wegovy are based. According to the Canada patent databasethe status of this patent is that of “expired and beyond the reversal period.” According to the Canadian Law, companies have a 12 -month grace period for claims and payment of late payments (another 150 Canadian dollars today). A period that would have already exceeded. Rubbing his hands. History began to reveal itself earlier this month. In an interview With the media specialized in pharmaceutical industry, Richard Saynor, CEO of Sandoz, talked about launching a generic medicine based on the peptide similar to glucagon 1 (LPG-1), the hormone to which the semaglutida to make its antidiabetic and slimming effect. As Lowe explains in his piece, the competition in the generic market can become “extremely beast.” Companies dedicated to this type of drugs seek as much as possible the patents, looking for failures that can invalidate them and thus be able to enter new markets. And today there are few markets as tempting as that of agonists of the GLP-1 hormone receptors such as Ozempic, Wegovy or Rybelsus. This family of drugs, oriented in its origin to treat diabetes, has achieved immense success for its slimming effect, triggering a whole revolution not only pharmaceutical, but also economic. A permeable border. An important detail mentioned by Saynor in its interview is that Canada is the second major semaglutidal market (after the United States). This would not be, speculate, because Canadians are great consumers of the drug, but is probably a consequence of the cross -border business. “There is clearly a dynamic, as with insulin, with business through the border,” Explains the director of Sandoz. “It will be interesting how this evolves,” he says. Evil of many … The expiration of the patent in Canada would not only affect Novo Nordisk but also could suppose a hard blow to its main competitor in the diabetes treatments and weight loss, the American Eli Lilly. The entrance into the market of a generic competitor would imply that the manufacturing company of Zepbound and Mounjaro. These drugs are based on the tirzepatida, a compound that acts as an analogue of the LPG-1 and also of another hormone called polypeptide gastric inhibitor or GIP. A mistake? An error? We began pointing out that patents are a fundamental pillar of the pharmaceutical industry which makes the doubt prevailing: why? It is difficult to know if everything is due to a simple error or a calculated strategy. “I never knew why this is sure that someone lost their job, but it doesn’t matter,” Saynor held in his interview. If it were a mistake, it would not be a mere mistake. According to Lowe explainsthe company showed in writing there by 2017 its reluctance to the payment of the maintenance rate of the Canadian patent of the Semaglutida. He boom Ozempic would not be given until years later, because perhaps the company was not able to anticipate success and considered the price of maintaining a patent in the North American country. In Xataka | In search of “natural ozempic”: what science knows about diets that simulate the effect of miracle medications Image | Rene Baker / Chemist4u

We have been believing that Iran is “five years” from the nuclear bomb. In reality we only know how much uranium enriches

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Few phrases have been as repeated in the geopolitics of the West as “Iran is five years from the nuclear bomb.” For more than three decades, we have heard predictions that place the Iranian regime on the verge of crossing the atomic threshold, a stopwatch that restarts again and again without the prophecy becoming fulfilled. The real problem is not so much what we know about Iran’s nuclear program, as the immensity of what we do not know. And it is in that fog of uncertainty where the most dangerous decisions are cooked. A diffuse red line like Casus Belli. Israeli Prime Minister Benjamin Netanyahu has initiated a war against Iran framed in which the regime is “close to finishing the construction of a nuclear bomb.” This language transforms an old threat into an immediate danger, turning the rhetorical red line into a justification for war. Although the United States initially denies direct participation in the attack, political and military support has gone in crescendo. A Message of President Donald Trump In capital letters, “Iran can’t have a nuclear weapon!”, It works as a blank check for Israel. Thirty years of breached predictions. When a suspicion, and not an evidence, they are a reason for war, it is worth reviewing the newspaper library to put rhetoric in perspective. The feeling of “imminent nuclear bomb” in Iran is not new. It is a political construction that has been managing for decades, with Benjamin Netanyahu as its main architect. In 1992, Netanyahu already warned that Iran was “three or five years” to obtain nuclear weapons. In 2012, he starred in one of his most iconic moments at the UN, drawing a red line with a marker In a cartoon scheme of a pumpand ensuring that they would cross the line in the summer of 2013. Each period has been fulfilled without the weapon becoming materialized. What do intelligence agencies say. Although Israel had in the United States its main political ally, US intelligence agencies did not buy their rhetoric about Iran. In 2007, the National Intelligence Estimate De la CIA concluded with “high confidence” that Iran had stopped its nuclear militarization program, the AMAD Plan. The verification of this break came in 2015 with the Comprehensive Comprehensive Plan Joint (JCPOA), an agreement by which Iran limited uranium enrichment to 3.67% in exchange for the lifting of sanctions. The break that caught the fuse. Paradoxically, the withdrawal of the United States of the JCPOA in 2018, driven by the same rhetoric of the “imminent bomb”, caused the response that was intended to avoid. Iran began to enrich uranium at unprecedented levels: first 20% and then 60%, drastically shortening the theoretical deadlines for the pump and triggering the current crisis. Despite this, there are no evidence, beyond the expansion of enrichment plants, that Iran have the necessary technology or develop those weapons. Although, in honor of the truth, it is logical that there are no, since most of the activity is underground. Faith jump between enrichment and nuclear bomb. To understand how “near” Iran of the nuclear bomb is, you have to differentiate two key processes. The first is the fuel: the enrichment of uranium, the visible part of the process. It is about increasing the concentration of the fistible isotope 2 35 of the uranium from the 0.7% natural to 90% (the arms degree). Thanks to the withdrawal of the JCPOA, Iran accumulates a large amount of 60%enriched uranium. And moving from 60 to 90% is a technically feasible leap within a few weeks. However, Having the fuel is not having the enginewhat Anglo -Saxons call “weaponization.” A set of incredibly complex steps to convert the fistible material into a functional eye that can be mounted on a missile. They have to convert the uranium of arms degree, which is a gas, into a metal sphere. They have to surround that sphere with high precision explosives that have to detonate simultaneously in microseconds to compress the nucleus and start the chain reaction. And all this, in a package small and light enough to fit in the eyes of a missile and survive the launch. This is where we enter the field of almost total uncertainty. We know that this will investigated with the AMAD Plan, but its current progress is unknown. However, nobody knows it with certainty because intelligence on underground activities is very difficult to obtain. What we know with certainty. Despite decades of sanctions, sabotage, selective murders of its scientists and cyberbrains (like the famous Stuxnet, which destroyed uranium centrifuges), the Iranian nuclear program has not only survived, but has become stronger and more self -sufficient. Iran designs and produces its own advanced centrifuging. In fact, Israel’s main objective is to destroy the Fordow plant, that Iran built under a mountain to make it invulnerable to air attacks. In parallel, Iran has developed the largest and diverse ballistic missile program in the Middle East, and a fleet of trucks ready to shoot them. This resilience demonstrates that technical knowledge is deeply institutionalized in the regime, which is why Israel has eliminated those responsible for the nuclear program, as well as Iranian launches. At the same time, each Israeli attack can reinforce the conviction in Tehran that the pump is the only guarantee of survival, a fish that bites the tail, accelerated by Netanyahu’s rhetoric. They will go in the North Korean mirror or Pakistan. Beyond the rhetoric of the West, two countries offer key lessons about Iran. North Korea built its nuclear program to ensure the survival of the regime. Isolated and economically devastated, He saw the bomb as his only insurance policy against a overthrow imposed by the United States. The sanctions and pressure only reinforced their determination. Pakistan followed a strategic imperative. It sought to neutralize the military superiority of India. When India tried her bomb in 1974, the Pakistani bomb became a matter of national survival. Iran is a hybrid and more complex case. Share the survival … Read more

23 years ago China gave the US a lesson. Thanks to it today dominates the battery industry overwhelmingly

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The German-American physicist John Bannister Goodenough patented the technology that allowed to manufacture Iron and lithium phosphate batteries (known as LFP for its English denomination) in 1997. In 2019, when he was no less than 97 years, he was awarded the Nobel Prize for his contribution for his contribution to the development of lithium ion batteries. However, Goodenough made a mistake. An important mistake: he failed to transfer his innovation to the American industry, so its impact on the West was minimal. Wang Chuanfu, the founder of the Chinese company Byd, did not make that mistake. In 2002 he perceived the potential of the technology that Goodenaugh had invented, so he asked his research and development team (R&D) to investigate the technology and capabilities of LFP batteries with the purpose of minimizing the dependence that China of the nickel and cobalt had. That decision I guide Byd towards the leadership position Shared with Catl currently occupied in the battery production industry. In fact, in 2008 he placed in the market The first car in the world Equipped with an LFP battery. China manufactures 57% of the batteries used by electric cars China is currently The largest electric vehicle market of the world. In 2025 in this country more electric cars will be sold for the first time than with combustion engine thanks to some extent to government subsidies. In addition, China is the largest electric car exporter on the planet. In 2023 he exported approximately 1.7 million electric vehicleswhich represents more than 30% of its total car exports. However, its international expansion is being seriously conditioned by the tariffs that are imposing USA or the European Union, among other regions with very serious difficulties to compete with the Chinese electric car. Finally, as we have seen, China is also a world leader in The production of lithium batteries. If we stick to electric cars the country led by Xi Jinping Fabrica 57% of batteries that these vehicles use. CATL and ByD are the largest lithium batteries on the planet with a market share in 2024 of 37.9% and 17.2% respectively, according to the consultant Sne Research. In 2017 for the first time the market share of NCM batteries surpassed that of LFP in electric cars China has reached this leadership position due to several factors. On the one hand it is The largest producer in the world of lithium and rare earths, which are the main raw materials used in the manufacture of batteries. In addition, it controls the processing of these materials and is capable of producing large -scale batteries and with a very competitive price. However, in this recipe there is one more ingredient that we cannot overlook: byd and Catl lead the global battery industry thanks to their capacity for innovation and adaptation. In 2017, Chinese government subsidies prioritized the development of Nickel batteries with greater energy density, so much of Chinese battery manufacturers opted for NCM technology. These lithium -ion batteries use a nickel (ni), cobalt (co) and manganese (mn) cathode, hence their name. And byd lagged. In fact, in 2017 for the first time the market share of NCM batteries surpassed that of LFP in electric cars. And in 2019 the NCM batteries already dominated the market. But Byd did not give up. Wang Chuanfu was convinced that the really important security was, and, therefore, the thermal stability of the batteries, so it launched a new R&D project that concluded with The tuning of Blade batteries. These devices are thinner, have modular structure and can be easily integrated into the chassis of electric cars. This bet went well to Byd. At the end of 2020 this company and catl They controlled 66% of the Chinese market of the LFP batteries for electric cars against 6% that added in 2019. This is the authentic strength of the two Chinese companies that lead the world battery industry. Image | Byd More information | Volt Rush In Xataka | Historic record for China: its chips industry has produced in 2024 more than ever despite the sanctions

We have found in the Philippines the remains of an advanced culture of navigators about 35,000 years old

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When did the human being thrown into the sea? The human being has had a close relationship with the maritime environment from the dawn of history, but we know that this link comes from beyond what our collective memory reaches. We knew that in the stone age our ancestors were able to throw themselves into the sea. Now we began to see that perhaps their techniques were even more advanced than we thought. Advanced technology. A team led by Filipino researchers has found remains that would correspond to a prehistoric culture With advanced maritime technologies. This culture would have reached Mindoro, one of the Philippines that never in recent geological history has been linked to Continental Asia, at least 35,000 years ago. A variety of artifacts. The team’s conclusion is based on a series of objects found in Mindoro deposits, a medium -sized Filipino island located north of the archipelago. Among the objects found are human and animals, including marine animal shells; as well as tools made with stone, bone and the shells themselves. The team The existence stands out of a culture that will use shells as raw material in the manufacture of tools within the temporal framework of the finding. The deposits, which cover objects of various ages, also include azuelas made of the shells belonging to specimens of the genus Tridacnathe “giant clams.” The inhabitants of Mindoro would have reached this climax of their maritime manufacturing between 7,000 and 9,000 years ago. Dominating the seas. The fact that humans reached this island already implies an indication of a certain relationship with the marine environment, but the team also found rudimentary hooks made of bone, as well as objects that would have been used as weight in fishing networks. A “maritime network.” The team also found a more modern grave, about 5,000 years old. As explainedthe burial could be linked to others found in various parts of Southeast Asia, which would suggest “shared ideological and social influences and an emerging social complexity throughout a vast area from the continent to the distant islands.” The details of the study were published In an article In the magazine Archaeological Research in Asia. A different map. The last glacial period began about 120,000 years ago and would not end until about 11,500 years ago. During that period the volume of ice in the polar areas was greater, so the sea level was lower. Environments like Mindoro They serve as an important reference To know better how, where and when the human being achieved owner of the sea. The Pacific conquest. The discovery fits with the predominant hypotheses indicating that the human being began its expansion through the Pacific Ocean about 45,000 years agostarting from Southeast Asia to New Guinea and Australia. Of course, it would not be until many millennia later (about 3,500 years ago) that humans would begin to expand their habitat to more remote archipelagos such as Samoa or Hawaii. The new study gives us therefore valuable information about how the humans of that era achieved the inhabitants of Asia to achieve the necessary dominance of the sea to undertake the most recent and perhaps the most surprising of the great migrations, the conquest of the Pacific. Millennia sailing. We began with the question of when the human being was thrown into the sea. It is a difficult question to answer since technologies such as navigation could appear in different historical moments and in different geographical and cultural contexts. It may even that the first humans to navigate did not belong to our species, the Homo sapiens. Who then? Probably some species closely linked to ours as Neanderthals (Homo Neanderthalensis); or the mysterious “flowers of flowers” (Homo Floresiensis), more related to the H. erectus. The older indications What do we have and that date back about 700,000 years ago They are linked precisely with this group that would have inhabited the island of Flores, in Indonesia, not so far from the Filipino archipelago where we have now discovered a new piece in the puzzle of human navigation. . In Xataka | We have found 21 human remains of 6,000 years ago in Colombia. They do not look like any current living population Image | Manila / Gebco Athenaeum

Participate in our draw and earn 20 double entries to see ’28 years later ‘in cinemas

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’28 days later ‘is one of those films that feel precedent in a genre and that never go out of style. It is considered one of the masterpieces of horror and science fiction cinema, and its “infected” proposal (not so much “zombie”) has permeated to this day. After a successful sequel released in 2007, in just a few days, on June 20, it will be screened exclusively on cinemas’28 years later‘, the Third installment of the saga. Well, with a little luck, you and a companion can go see her completely free. The reason? That from Xataka, and by the hand of Sensacine, Let’s overcome 20 double entries. Participating is very simple and you can have not one, but two awards. We tell you more right away without any spoiler of the new film. How to win 20 double tickets to see ’28 years later ‘ Getting one of the 20 double tickets to go to the cinema to watch the new Danny Boyle movie is very easy: you just have to Point to the Scream Club of our Sensacine companions Through this form. The members of this club will have the opportunity to attend special and advanced projections of the latest premieres of horror movies, among many other advantages. Legal bases here. With just signing up, you will participate in the raffle of the tickets, but it goes more. One of the keys of the Scream Club is that, after each film session, the members can score the movies, give their opinion and, among all, grant the seal of “masterpiece”. Well, those who belong to the club, go see the movie and score it in Scream Club can also participate in the draw for two headphones Sony Ult Wear. Legal basis available in this link. About ’28 years later ‘ Attention: Spoilers of the first two films below. As you already know everything in horror cinema, ‘28 days later‘It places us at the beginning of this zombie apocalypse, when a group of activists enters a British laboratory and releases primates infected with a modified rabies virus. This virus, which is transmitted by saliva and blood, infects people and makes them violent and thirst for blood. In just one month, all the United Kingdom ends up succumbing to infection. In the absence of new dams, the infected end up starving. Six months, or ‘28 weeks later‘(Name that received the sequel), the outbreak is considered content. NATO forces enter London and begin an attempt to repopulation that is frustrated when an infected person, but asymptomatic, causes a new outbreak. In the end, the virus manages to cross the puddle and reach Europe. The film ends with a horde of infected running around the Eiffel Tower. ’28 years later ‘will tell us how survivors have adapted to a world full of infected And we get to ‘28 years later‘. This film, directed by Danny Boyle and starring Aaron Taylor Johnson, Jodie Eating and Ralph Fiennes, will premiere exclusively in cinemas on June 20 and tells us how some people have managed to adapt and survive in a world full of infected. A group of these survivors inhabits a small island connected to the continent by a single highly protected and guarded road. One of the members decides to venture in the continent, discovering all kinds of horrors and secrets related not only to those infected, but to other survivors transformed because of the virus. It is a movie that will be Visceral, terrifying and that will delight fans to scream in a movie theater. Cover image | Sony

Córdoba has been trying to finish a road for 20 years. Now they have encountered a problem: Ruins Mozárabes

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Doing works in a city like Córdoba is a risk task. From time to time, in Spanish cities we find new vestiges of previous eras. An example is the ruins under the door of the sun or the Otero orchard deposit in Mérida. Córdoba is another level and, during preventive excavations under the layout of a future and important road, they have found new Christian ruins. They are not just a few more archaeological remains: this finding provides unique context to the coexistence between Christians and Muslims in Islamic Cordoba. Short. The northern round of Córdoba will be the road that It will close The city ring. It is a complex project that has been carried out in phases and that has been controversial Due to neighborhood complaints motivated by noise that will generate the increase in traffic. During preventive excavations, and how we read in Cordopolisthey found something that will further delay the project: a set of structures that date back to the seventh century. And the date is relevant because it would contribute new context to the Córdoba of those first decades of Islamic domination. By layers. Córdoba is a large city, but the Islamic Córdoba was even greater. With the passing of the centuries, the city was diminishing due to the new urban projects, which were building on the remains of the past. Mosque itself is an example of that construction in phases and, although in an exaggerated way, of that building on the above. When it is excavated to do works, it is not uncommon to run with remains of Islamic neighborhoods, but the interesting thing about this new finding is the cult difference: the Christian. A cult that, due to the progressive Islamization from the city, he left displacing towards the most peripheral areas. The remains. In Cordopolis, Alberto León, professor of archeology at the University of Córdoba, comments that there was a record of the destruction of Christian temples at the dawn of the seventh century. Subsequently, Abderramán’s “pact” was allowed, allowing the coexistence of the cults. The problem is that no remains of those constructions made by the Mozarabic. That is why the complex discovered under the future North round Be so relevant. Presents Tapial walls (clayey earth compacted with blows) and a pool of about 50 meters. Archaeologists have been inspecting the place since the end of last year, and it is now when they point out that it would be a monastic building, probably divided into areas for men and women, with clarifying columns arranged, as you can see in the photosaround a patio and that the pool could be a baptistery. The lost basilica. Ángel Ventura is a professor at the University of Córdoba and one of those who is inspecting this monastic complex. In Córdoba newspaper He launched the hypothesis that the ruins could belong to a possible basilica in honor of Santa Eulalia de Mérida. It was a martyr that had great importance for the Cult in the city And there were documents that implied the existence of “their” basilica, but without having been found. Clue. In the end, this discovery will allow to have more context about the coexistence between Christians and Muslims, but it is also relevant because, according to Alberto León, “is one of the two examples of existence of a Christian cult complex in Islamic neighborhoods.” The researchers continue to study the place to determine their function, chronology, when it was abandoned and launch hypothesis about the coexistence between the different cultures of the city. What is clear is that there had to be many more like this in the suburbs, so future excavations could even show more context about that peculiar era of religious coexistence in the Islamic Córdoba. And also that it would be necessary delay or even rethink the work of the road to be able to study this important finding. Image | Toni Castillo Quero, Dolores Mª Macías Naranjo In Xataka | The dilemma of Córdoba is that of many other Spanish cities: install plates or conserve its heritage

We have found a skull from 6,200 years ago cone and signs of violence. The big question is what I was doing there

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The last cry in bodily modifications is the Implementation of chips under the skin to become One more element of home automation Domestic But we have millennia modifying our aesthetics In a little invasive way, such as The Ötzi tattoos With more than 5,000 years, or in more aggressive ways, such as Padaung They push their clavicles. What they have found in a cemetery near Iran goes much further: a skull from 6,200 years belonging to a woman with a cone -shaped head. And the thing didn’t end well. Chega Sofla. In the western zone of Iran is the site of Chega Sofla. Researchers have been investigating the site for years and Nonantring bodiessince there are dozens of tombs in which they have been found from individual burials to burials of complete families. Some of the human remains They show that, in life, certain people had a more stretched skull than normal not by any kind of natural deformation, but by aesthetics. And, among all, the one who has called the attention of archaeologists is one of those skulls that shows signs of a brutal blow that ended his life. And beyond how, the interesting thing is why and what that young woman did. Cone head. Called as BG1.12, the life of this woman ended when she gave (or led to her) a Strong blow to the head. Before that, it must have been one more because this cranial modification was quite common. What were done in many ancient civilizations was to wrap the infant’s head with bandages that were squeezing as they grew. Like a splint. This practice, extended until adulthood, prevented the skull from developing in a normal way, resulting in a more elongated, cone -shaped skull. And, although it was a normal practice that was given more in girls than in boys, we now know that it was not a good idea. Dangerous. The striking of the wound of BG1.12 led archaeologists to investigate On the cranial development that these people had, discovering that, due to those tight bandages, both the bones and the Diploe (which is a more spongy bone layer that is between two more compact layers in the skull, as if it were a “shock absorber”) were much thinner than those of a typical skull. This is drawer, but explain that it is something that prevents the skull from exercising its optimal brain protection work. Due to that thinness, before external forces, the “brain shield”It is less effective. At some point in the twenties of that woman, something managed to fracture that weak cranial layer, ending her life. The researchers, in statements to Livesciencethey claim that the blow would also have ended with a person who had a normal skull and who do not know if he received an attack or hit himself. What is known is that it was buried in a common grave next to people with both normal and modified skulls. The skull of BG1.12 that shows the wound The role of women. To affirm that the person would have died even with a normally developed skull, he takes away a lot of mystery to history, but the big question is what role people with modified skulls played in that society. We have found modified skulls in European womenin Japan and in Mesoamerica and reasons that are considered They range from Demonstration of status until the search for differentiation of nearby villages or the approach to the image they had of their divinities. Strictly motifs are also considered Aesthetics. The mystery of BG1.12 is that it was buried in the same pit as other people with both normal and modified skull and, as all the ‘stuck’ skeletons are, it is difficult to identify all individuals and know what role in society played these people with the deformed skull 6,000 years ago. And, above all, the moral is that this aggressive modification does not suit. A silly blow to the head, a diploe that does not act as it should … and goodbye. And put your head in a particle accelerator, if you ever have the opportunity, Nor is it a good idea. Images | Cambridge In Xataka | A cave has revealed the macabre Mayan ceremony to honor its gods: there are 100 bones and none is where it should

The problem is that they are girls under 10 years

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A few weeks ago, while queued in Druni with a shampoo in my hand, I heard two girls – you think of the 12 years – to discuss whether to buy a hyaluronic acid or retinol, both products of The Ordinary brand. A short time later, in the supermarket, three others of the same age were buying masks and discussed whether to carry a serum of vitamin C. Although the latter had a quick outcome: “We take it to my mother, she will not realize,” said one of them. Stunned by this scene, I did not avoid asking if this situation is increasingly common or if it is the reflection of an alarming trend. More and more cases. A quick review of social networks confirms that the Alpha generation (born after 2010) It is obsessed with the Skincare and makeup, driven by networks like Tiktok. But behind the hauls of products and 10 -step routinesthere are real risks: allergies, dermatitis, self -image disorders and even exposure to endocrine disruptors. The problem. A recent study Posted in Pediatrics He analyzed 100 Tiktok videos where girls between 7 and 18 years showed their facial care routines: they used an average of six daily products (some up to twelve), with ingredients such as exfoliating acids or peptides. The result is evident and visible from irritations, cosmetic acne to sun sensitization. However, the damage goes even further, like He explained to The Guardian Dr. Molly Hales, director of the study, “76% of products contain allergens as fragrances.” In addition, only 26% of these routines include sunscreen, which causes a concern about skin health. The virality for perfect skin. “We have entered an era where childhood sells us in jars of aesthetic products,” He has denounced In The Independent Ellen Atlanta, author of Pixel Flesh: How Toxic Beauty Harms Women. What began as sporadic masks has become a crisis: girls who at 10 years They use retinoids -Ingredient for mature skins– while influencers in Tiktok promise “crystal skin”. From Save the Children They already warned of the exhibition of minors on social networks, where 58% of children from 10 years navigate on the network. What the skin says. Dermatologist Emma Wedgeworth He has warned in The Independent That the use of inappropriate products can deteriorate the skin barrier and increase the risk of allergic eczema and dermatitis. However, there are more and more girls between the 8 and 15 years that suffer what experts call cosmeticorexia, a compulsive need to use unnecessary cosmetic products, even harmful, according to The Spanish has detailed. A market niche. Marks, social networks and, often unintentionally, parents themselves are sending the Alpha generation towards this new consumption, since they are easily influenced and are constantly connection. Just see how Sephora or other stores have turned the Skincare In a children’s party game. The recommendations are clear. Both dermatologists and psychologists have coincided with the same: limit access without supervision to social networks, provides real self -esteem models and maintain a simple care routine based on cleaning, hydration and sun protection. “10 -year girls who think that without makeup are not worth enough. It is an alarm sign,” He explained The psychologist Jennifer Cano in Spanish. Beyond aesthetics. Instead of occupying the parks or playing with toys, a turn is being observed for the fashion trends of social networks. Now we must bear in mind that these interests, far from being a passing phase, are integrated from an early age and mold the relationship with the body and image over time. Image | Tiktok Xataka | There are people recommending to sew the leg on albal paper. There is zero evidence to work

15 years ago, diesel got the best record in the history of Le Mans

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In a few hours they will start 24 hours from Le Mans. A year ago, in Xataka We had the opportunity to be there. I remember the expectation of the minutes before. We arrived with hours of advance but in Le Mans you breathe nervousness from the early morning. Those nerves that cause a smile contained halfway between illusion and fear. I wasn’t there 25 years ago But I’m sure something very similar was lived. The 2000 race served to collect the new millennium with open arms. What we did not know is that one of the most dominant eras in the history of the competition was beginning. One that starred Audi. One that began, like all, with a victory but that completely changed the idea of ​​understanding Le Mans. One that began with the smell of gasoline and ended with the smell of diesel. The golden years of Audi in Le Mans Although it was in 2000 when Audi won for the first time in Le Mans, the previous year he had already served the company of the four hoops to take temperature with the most famous resistance race in the world. In 1999, BMW had managed to impose itself as the last winner before the millennium change. No one predicted that during the next 18 editions a team got the victory in thirteen of them. And of these, nine joined consecutively. For the year 2000, Audi appeared again with his R8. He did it with a 3.6 -liter V8 engine with which they had already tried luck the previous year but made changes in the transmission. From the beginning it was confirmed that the three Audi were going to have very few rivals. Courage, Oreca, Dams and Panoz were not rivals for some Germans who added 368 laps with the unit piloted by Frank Biela, Tom Kristen and Emanuele Pirro. Audi copied the podium and his third unit added 368 laps. To understand the domain, the fourth classified was the C52 Courage that mounted Peugoet motor and only managed to add 344 turns. The distance was sidereal and would be certified in later years. Between 2000 and 2008, Audi scored each and every one of the victories of its LMP900 and, later, LMP1. Of the 24 possible drawers of the podium, Audi copied 19 of them with his official team or a private team that mounted any of his audi r8. The domain was overwhelming as we see but after three years dominating as an official team, the Germans left the competition and the Audi that were put in the starting line did it with private equipment. The situation was repeated between 2003 and 2005. But in 2006, the thing changed. Audi showed his interest again in the queen category of Le Mans but did it with surprise. He arrived with a diesel engine to show that fuel efficiency had no rival. The strategy was simple: less consumption involved less reposses and, therefore, longer on track. A diesel record And the strategy worked. In 2006Audi appeared at the starting line Of the 24 hours of Le Mans with two cars instead of the usual three to focus efforts. However, he managed to occupy two places of the podium, adding a 1-3 to his record and growing his private prustle account between 2000 and 2008. The car mounted a supercharged V12 with two turbocharger that could generate a maximum of 659 hp. According to its initial calculations, without shocks, the Audi R10 TDI He could take two more turns to the circuit of the pan than his predecessor before reproducing. That implied that he could travel 26 more kilometers before stopping. Although there had been previous attempts, that was the first year in which a car that used diesel fuel was made with the victory. It would not be the last because Audi repeated Victoria in 2007 and 2008. However, the fence was narrowed and in 2007 Peugeot also appeared in the output line with a diesel engine. In this case a Peugeot 908 HDI FAP that repeated the structure of the German: 5.5 -liter V12 engine and supercharged with two turbos. That year, the Peugeot went to 700 hp. In spite of everything, in 2007 Audi dominated again and put ten laps away to Peugeot. But the following year the competition matched so much that Audi and Peugeot added both 381 laps. However, the best would come. In 2009, Peugeot He finally managed to get the victory and did it with sufficiency, with the end of six laps above the Audi. A year later, the Germans would compensate getting one of the most spectacular records in history. In 2010, Audi returned to the three seats of the podium, already without Peugeot in the competition. The domain was so overwhelming that the first LMP1 No Audi It was a oreca that ended 26 laps from the winner. It was not for less, Mike Rocknfeller, Timo Bernhard and Romain Dumas managed to complete the cross circuit 397. They matched the number of turns achieved by Helmut Marko and Gijs van Lennep with a Porsche 917K In 1971 but there was a small difference. In the 70s, the circuit measured 13.47 kilometers, while in 2010 it had lengthened 13.63 kilometers. Those almost 200 meters apart, return to turn, made, since then, Audi shows the record of distance covered in the 24 hours of Le Manswith 5,410,713 km. The record was achieved with the Audi R15 TDI Plus. The car then rode an engine V10 5.5 -liter TDI that gave a maximum of 600 hp. It was an evolution of the previous year and served to find a winning path that extended until 2014, with change to hybridization along the way. The second half of the past decade became dominated by Porsche and Toyota (with that victory of Fernando Alonso included). The year 2014 closed, therefore, Audi’s most glorious story with Le Mans. Photo | Audi In Xataka | The most … Read more

We have been binding to the suitcases to identify them at the airport for years. Your employees warn that it is a bad idea

by

I do it. And you may too. Arrives with the billing zone of any airport in the world to verify that we are many, manywho tied tapes, scarves or cords to our bags to differentiate them. A striking colorful color. An old bracelet. A loop with a name. It doesn’t matter. The idea is that we can clearly identify our suitcase of those of the rest of the passengers. Mark it in an unmistakable way (or so we believe) so that according to Asome by the conveyor belt we know that it is ours. It turns out that it is not as a good idea as it seems. Well on paper … But not so much in practice. Although we are many who add tapes to our Trolleys Billed to identify them at a glance, that trick has its weak points. And the most curious thing is that it is the airport employees themselves who They are warning it. Hanging a tape or handkerchief of the ASA may help you locate your suitcase and expedite billing, but workers in charge of managing luggage can be a real complication. One that ends up lengthening the security controls of your suitcase … and affecting your Planning travel. “It can cause problems”. The warning was released recently John, in charge of luggage at Dublin airport, a huge infrastructure for which only last year they paraded near 32 million passengers. With their respective suitcases, of course. In statements To the Irish magazine RSVP Magazinethe airfield employee warns that, at least in certain cases, the signals we use to differentiate our invoiced luggage complicate the controls. To the manual. “The tapes that people bind to their bags to help identify them can cause problems when scanning them in the luggage room,” Clarifies the employee Dublin, and warns: “If the suitcase is not able to scan automatically, it can end in manual processing, which could mean that it does not reach the flight.” Result? A trick that seeks to speed up the trip and avoid losses at the airport would end up becoming the opposite: a big problem. Adds and continues of advice. It is not the only advice left by the employee of the Dublin terminal. So that the passage through the airfields is the most comfortable, fast and quiet as possible RVSP Magazine leaves three other ideas almost as easy to apply as unleashed the ties that we have been able to hang from our Trolleys. The first is in fact very simple: also remove the stickers of old flights. “They can cause confusion with the scanning process,” says John. The second is to place the wheels of the suitcase up to prevent damage while driving it. And the third, somewhat more picturesque but equally crucial: avoid the mazapanes in the travel bags, no matter how fond of these sweets based on almond. The reason? “It has the same density as some explosives, so they will remove the suitcase and call it from the plane.” Travel with luggage … and tricks. John’s is not the first advice on airports and luggage. He is not even the first to expedite the tedious process of waiting for our suitcase to appear for the conveyor belt. The newspaper a year ago The Sun published Two others to get your suitcases and other packages to appear in the luggage collection room: The first It is to place a sticker that identifies them as “fragile”, which will help them to be of the first to be discharged; The second is to make the Chek in and bill Later as possible. The latter, of course, is not suitable for cardiac … and can lead to more than one scare if the traveler does not calculate the times well. Images | Gary Bembridge (Flickr) and Friend Jad (Flickr) In Xataka | The airlines continue to charge for the hand suitcase despite the historical fine and they already warn: they will raise prices *An earlier version of this article was published in June 2024

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