tear

Gray hair is not wear and tear, it is a cleansing of our tumor cells.

by

For centuries, gray hair has been the universal symbol of aging, a simple aesthetic issue that reveals the passage of time or the excess of stress that sometimes occurs. it’s about covering with dyes. However, having gray hair can be good news for many people, since a study published in Nature Cell Biology just turned this idea on its head: white hair could actually be a biological defense mechanism. The fact that we begin to grow gray hair is for many people a great condemnation that reminds us that age forgives no one, and we even see young people with a lot of gray hair at an early age. But having gray hair can be a sign that is related to the risk of suffering from melanoma, which is one of the most aggressive skin cancers, especially when it is not caught in time. The dilemma of the cell. To understand why having a large amount of gray hair is good news, we have to go to the root of the hair. Here you will find the bulb of the hair folliclewhich is where the hair will grow. One of its fundamental components is the melanocyte stem cell, which is responsible for the pigment that gives color to the hair. That is why when these cells are affected is when you begin to have a color deficit. In this way, research indicates that when these cells suffer damage to their DNA, such as from exposure to the sun or according to agethe body activates a “checkpoint.” The mechanisms of action. When a cell with broken DNA appears on the scene, there is a chance that it will cause cancer if it begins to divide uncontrollably. In order to avoid this, stem cells use a process called “senodifferentiation” that causes the cell to stop dividing and be removed from the tissue. When these stem cells are eliminated, we are left without pigment reserves and the hair is born white, but the body has made sure to eliminate a potentially dangerous cell that could have generated a tumor if this defense system did not exist. The system may crash. Although our body has many defense systems to stop the proliferation of tumor cells, sometimes they fail and cancer is generated. Specifically, the study points to different carcinogens (including chemicals or UV radiation) that can ‘hack’ this cellular decision. Unlike pure radiation damage (which causes gray hair), carcinogens activate specific metabolic pathways (such as arachidonic acid metabolism) that force stem cells to survive and reproduce despite having damaged DNA. In this way, the stress of these carcinogens stimulates the stem cell niche to secrete a molecule called ligand KIT. This signal has the ability to block the “senodifferentiation” that we mentioned before, preventing damaged cells from being eliminated. The ‘good’ news is that the gray hair does not appear, but the bad news is that the damaged cells accumulate and expand, greatly increasing the risk of melanoma. There is, therefore, an antagonistic relationship: The fate of stem cells determines whether we will have gray hair or cancer. If the system works well, the cell is sacrificed and a gray hair emerges. If the system is circumvented by a carcinogen, the cell persists and the gray hair does not appear, but there is a greater risk of a tumor appearing. Aesthetic medicine. One of your goals right now may be avoid gray hair without the need for artificial dyes with the reactivation of these stem cells that have been ‘arrested’ and do not offer their pigment. But for these researchers we are facing a very bad idea. And they specifically point out that the repigmentation of gray hair in certain areas of the scalp could be, paradoxically, an early warning sign of melanoma, indicating that cells that should have ‘retired’ are returning to activity in an uncontrolled manner. In short, the next time you see a gray hair in front of the mirror, don’t just see it as a sign of old age. See it as a small victory for your body: a stem cell that decided to “retire” in time to protect you. Images | Alexandra Tran Natasha Brazil In Xataka | The rarest element on Earth aims to cure cancer. And Europe is already accelerating its production

An AIM-9X missile cost a million dollars to tear down a Russian drone. Ukraine has found the solution for 2,000 dollars

by

For Moscow, the Shahed drones They have been a cheap and scalable resource to wear out the Ukrainian defenses, first thrown into small batches and later in waves at greater heightoutside the reach of machine guns and cannons. For kyiv, the challenge has been not only to neutralize those swarms, but do it Without ruined: Each Shahed forced to shoot missile prices missiles, a long -term ruinous equation. This cost asymmetry forced Ukraine to accelerate innovation giving rise to a new air defense paradigm. The birth of something new. In the heavens of Ukraine an unexpected weapon has emerged against the incessant waves of Russian drones: the low cost interceptors Designed in Kyiv. Among them stand out The stinga projectile quadcopter capable of exceeding 315 km/hyred to destroy shaheds and gerberas in flight. Its tiny silhouette and acute sound contrast with the great traditional anti -aircraft systems, and their initial success (with hundreds of enemy drones demolished in a few months) demonstrates that it is possible to neutralize mass threats with fast and cheap solutions. Companies Like Wild Hornetsin collaboration with the Brave1 government platformThey have turned accelerated innovation into the country’s aerial survival axis. The cost war. The great challenge is not just technician, but economic. A Shahed drone costs $ 35,000, while The AIM-9Xused by systems Like Nasams To tear them down, it exceeds million per unit. This imbalance placed Ukraine already its allies in a clear financial disadvantage: each interception was tens of times more expensive than the Russian attack itself. The stinghowever, costs just $ 2,100 and acts as a suicide drone when impacting directly against the objective. The difference is abysmal: by the price of a single AIM-9x they can be manufactured Almost five hundred stinga proportion that explains why Kyiv considers its massive deployment vital to resist bombings of up to 800 drones in a single night. Accelerated innovation. The Ukrainian advantage does not only reside in the unit cost, but in the Radaptation apidity. Each new model responds to the last Russian tactic, either Shaheds to greater altitude, more numerous swarms or reaction versions. Engineers have gone from cannons and machine guns on land interceptors capable of operating partially autonomouslyand even experiences with totally automatic systems that detect, pursue and destroy without direct human intervention. This daily iteration capacity, fueled by the Front feedback, has turned Ukraine into a War laboratory unprecedented aerial. Europe and the lesson. The recent incursion of 21 Russian drones in Poland forced F-35 to deploy that used missiles of very high value to demolish just four devices. The episode has triggered European interest in Ukrainian solutions, which offer A “Drones Wall” much cheaper and scalable than any traditional system. German companies and other countries already Test interceptors Inspired by kyiv, aware that their current defenses are not prepared for cheap and massive waves. For Europe, the lesson is clear: the aerial defense of the future cannot be based on shooting millions from millions against objectives of a few thousand. New paradigm. The irruption of interceptors Like Sting It reflects a paradigm shift. What was previously resolved with very expensive static and arsenal systems now requires flexible, economical and serial solutions. Ukraine, pressured by the urgency of surviving, has made its way Towards a model in which the cost, speed and constant innovation weigh as much as pure technology. If you get displayed Thousands of daily interceptorsnot only will it reinforce its immediate defense, but it will have seated the foundations of a new military approach that will force NATO to rethink their strategy and to abandon the logic of the “Millonada” worn in each missile in front of an enemy that bets on the saturation and wear. Image | Wild Hornets/Telegram In Xataka | In a crucial Ukraine agreement he has given the US his best weapon. In return he has received something unpublished: a map to knock Russia In Xataka | Something has gone out wrong in Ukraine. So much, that the drone war has reached the most unexpected place: Türkiye

The mountains of Aragon are plagued by Christian crosses. Now there is a battle to tear them down or maintain them

by

Aragon lives his peculiar “Cruces War”. One that has begun in the mountains of the region, has jumped to the administrations and threatens Finish in the Courts. And all following a crucifix of several meters installed in the Sierra de Albarracín, a construction that has divided part of the Aragonese political class and society: for some it is a symbol that It must be preserved for its heritage, historical and symbolic value; For others, an element that must be withdrawn by representing a danger or directly crash with the aconfesionality of the State. The debate is served. The beginning of everything, a ray. If Aragon has faced his particular “battle of the crosses” for a few weeks, it is for lightning. A few months ago, In September of 2024, the Sierra de Albarracín suffered a storm that affected THE CROSS OF BEZASa monument of several meters high and several steps located on top of a rock. The cross did not fall, but it was affected by a ray that, Precise Diario de TeruelHe broke part of the concrete and gave a scare to a guard. What happened? The episode was a problem for several reasons. The ray was supposedly splintered part of the stone that covers the metal structure of the cross and the fragments fell near a guard. Enough for the Provincial Environment Service will send a letter to the town hall in which he proposed to withdraw the monument. Among other reasons alleged that it acts as a lightning rod during storms, a risk that could now increase that its metal is air. “An environmental risk”. The regional report in which it was argued that the cross represents “An environmental risk” convinced the Consistory, that He gave green light to demolition. Beyond the danger it can represent, the cross is popular in the area (it names the Peñasco on which it rose), but it is not especially old nor is there a clear unanimity about its historical value. The monument was installed in July 1939in memory of battalion 135 Bailén, but Alfonso Casas, expert in the Spanish Civil War, I explained recently In an interview with Diario de Teruel that in his opinion “it is not properly a vestige of the war.” Moreover, in his opinion he also does not have a special artistic value. And the debate arrived. Not everyone thinks the same. The decision to tear down the cross He didn’t like it For example to Christian lawyers, who a few days ago filed an appeal before the contentious-administrative court of Teruel. Its argument is simple: the cross has been in the same state for several decades (they presented a video in which they ensure that it can be seen how in the 80s the structure already had the pampering damages that now blame the lightning), so there is no reasons to remove it from the rock. “This monument, erected in 1939, reaches three meters with the base and is an important symbol of Christianity in the valley,” Highlight entitywho complains that “everything that recalls that Spain is and must remain Catholic” produces “a strange hives” in institutions. To reinforce his claim he has also initiated a collection of signatures that backed by more than 13,300 people. Beyond the Cruz de Bezas. So far the case is interesting but basically affects the municipality of Bezas and its neighbors. If you have caught the attention of state media It is because the debate has climbed and that September ray has put in the point of view other religious monuments distributed throughout the Aragonese mountains. One of the key actors of that debate has been Vox, which He has taken advantage to go beyond the decision of demolition of Bezas. His spokesman in the courts of Aragon, Alejandro Nolasco, has advanced Two party decisions. First, claim in the courts to keep the Cross of Bezas. Second, promote an initiative for “all historical and artistic goods that the Taliban of the PP and PSOE want to destroy” are declared BIC. “We are going to live times in which the crosses are going to tear down putting environmental, landscape excuses. Of course, free way for mills and plates.” “Contributes to degradation”. Vox has already proposed to achieve BIC’s tag (and armor) sights Located in the Old Pueblo de Belchite, Los Pinares de Venice, Monzón, Barbastro or Teruel, where he also wants protection to The cross located in the Plaza del Seminario. However, another group that advocates something very different: the Movement towards a secular state (Mhuel). In fact the entity has launched A campaign to demand the withdrawal of religious symbols distributed by the Summits of Aragon. “Aragonese mountains are fragile spaces that already suffer strong pressure from human activity,” The association arguesthat insists in that the presence of metal crossings affects the ecosystem and are a danger for hikers, especially during storms. “The installation of artificial elements contributes to the degradation of these spaces, many cataloged.” The great background debate. It is not the only argument that Mhuel wields, which also points to the great background debate: religious symbols in the middle of the mountain. “The presence of Christian symbols in public natural spaces contravenes the principle of aconfesionality of the State collected in our Constitution,” ditch: “The mountains are heritage of all citizens, regardless of their beliefs, and must remain free of religious symbols that represent only one part.” Hence the entity advocates extending Bezas’s criteria. But … how many are there? Good question, difficult answer. Bezas is not the only cross that crown rocks or peaks. In La Peña Oroel There is another very popular, just like that of The top of Anetowho jumped to the media in 2013 after the Benasque City Council decided to withdraw it to repair it. In 2024 Today Aragon needed That in the mountains there are different types of crosses with a religious or civil value, from indicators of sanctuaries or hermitages to guides for pilgrims, tributes to deceased or … Read more

Log In

Forgot password?

Forgot password?

Enter your account data and we will send you a link to reset your password.

Your password reset link appears to be invalid or expired.

Log in

Privacy Policy

Add to Collection

No Collections

Here you'll find all collections you've created before.