We thought that the problem of insomnia was on the mobile screen. Science points to the harmless five o’clock coffee

There is a ritual that many of us follow without questioning it. We arrived at five in the afternoon with our brains fried, we ordered a coffee—or a tea, or a Coca-Cola—and we continued. It’s the push we need to get through the rest of the day. What almost no one knows is that that five o’clock coffee may be sabotaging your eleven o’clock sleep. What we usually do when we don’t sleep well is point to our cell phone, stress, late dinner, or looping thoughts. We rarely point to the cup. And yet, for doctor Pablo Ferrero, a specialist in sleep medicine, the answer is there: “Caffeine is the number one enemy of good rest.” The chemistry behind the problem. To understand why caffeine is so disruptive, you have to know adenosine. It is a substance that the brain accumulates during waking hours and that, when it reaches a certain level, gives us that feeling of tiredness, that it is time to stop. It is, in a certain sense, the biological alarm of sleep. What caffeine does is to block adenosine receptors: Silences the alarm without disabling actual fatigue. The body continues to accumulate fatigue, but the brain stops perceiving it. The problem is not just that it is difficult to fall asleep. It’s what happens inside while we sleep. A study published in the Journal of Clinical Sleep Medicine found that a dose of 400 milligrams of caffeine consumed six hours before bedtime significantly reduced sleep efficiency. Other job in Neuropsychopharmacology was more specific: Consuming caffeine before bed reduces the amount of REM sleep, the phase in which the brain consolidates memories and regulates mood. More in depth. The numbers They are concrete and not very reassuring.: That dose can delay sleep onset by up to 45 minutes and reduce deep sleep—NREM phases 3 and 4—by up to 20%. Taken to everyday practice: if you have a coffee at 5:00 p.m. and go to bed at 11:00 p.m., your deep sleep can go from the usual 120 minutes to just 96. That’s 24 minutes less brain and physical repair. Nightly. But there is something even more disturbing: a scientific review published in the magazine Nutrients concluded that caffeine can reduce deep sleep even when the person sleeps eight hours continuously. That is, it is not enough to add hours. Quality does not always coincide with the perception of having a good rest. You can wake up thinking you’ve had a great night’s sleep while your brain hasn’t gone through the cycles it needed. Time matters. One of the most common mistakes is to think that afternoon coffee “no longer works” because you are used to it. Tolerance reduces the perception of the stimulus, but The half-life of caffeine in the body is between 4 and 9 hours: That means that half of what you drank at three in the afternoon is still active at eleven at night. And the problem is not limited to coffee. Caffeine is also present in some soft drinks, energy drinks, teas and chocolates, something that Ferrero expressly points out as a factor that goes unnoticed. It’s not just the breakfast cup: it’s the entire consumption circuit of the day. The broken clock. Caffeine, however, does not act alone. Ferrero points to another factor that can be even more decisive: schedule disorder. The body works through the circadian rhythman internal biological clock that regulates when we feel sleepy and when we are alert. When schedules constantly change—we go to bed at eleven Monday through Thursday and one o’clock on Fridays and Saturdays, and we get up three hours later on Sunday—that system loses synchronization. science back this up with data: Sleeping at irregular hours can cause insomnia, daytime sleepiness and alter hormone production, metabolism and eating habits, increasing the risk of diseases such as diabetes, obesity and depression. The impact don’t stop feeling tired Since while we sleep, the brain eliminates the beta-amyloid protein, accumulated during wakefulness and directly related to Alzheimer’s and other neurological disorders. Poor sleep is not just a tomorrow’s problem: it is a long-term investment—or debt. The motive is not innocent either. But the mechanism is more precise than is usually explained. The blue light emitted by screens suppresses the production of melatonin, the hormone that signals the brain it’s time to sleep. A study by the Barcelona Institute for Global Health warned that this overexposure directly alters the sleep-wake cycle. Just two hours of exposure to bright screens before bed can reduce melatonin levels by 20% or moreand the time to fall asleep can go from 15 minutes to more than an hour. Using a tablet before going to sleep can delay nighttime sleep by up to 96 minutes; that of a smartphone, up to 67. Harvard Medical School noted that “just a few minutes of screen stimulation can delay the release of melatonin by several hours and desynchronize the biological clock.” The problem is that we live in a society with increasingly irregular patterns: high light exposure at night, changing work schedules, screens until the last minute. We are sending our brain signals that it is still daytime when it is no longer daytime. So what works? Ferrero’s answer is not particularly glamorous, but it is supported by evidence. Going to bed and getting up at similar times every day—even on weekends—is the most basic and most ignored advice. Added to this is a dark, quiet and cool bedroom: artificial light and high temperatures send alert signals to the brain that make it difficult to rest. Avoid screens before going to bed—at least 30 minutes—and have a light dinner, without excess fats or spicy food, close to bedtime. For those who do not have insomnia, a short nap may be beneficial; The key is that it does not exceed 25 minutes so as not to disturb your night’s sleep. And in the face of anxiety or thoughts in a loop, Ferrero points out tools with scientific evidence: … Read more

Most people take creatine for the gym. It is actually really useful against insomnia.

for a long time Creatine has been seen as a supplement intended for people who go to the gym to have a good muscle. However, this is changing completely to recommend that anyone take creatine for the many benefits of taking creatine to improve cognitive functions for example. Now, it is also being seen that it has a great component for the quality of life in people who suffer insomnia. Sleep deprivation. The human brain represents only 2% of body weight, but consumes 20% of our body’s total energy. The main cfuel it has is ATPthe currency we use, and its ability to quickly resynthesize it determines our mental agility. But when there is sleep deprivation, energy levels drop and with it attention, memory and mood. This is where creatine comes in, as a large study published in Nature in the year 2024which changed what we knew about acute creatine supplementation in anyone. In this case, the researchers demonstrated that a single high dose of creatine is capable of reversing the cognitive deficit caused by little sleep. The results. Specifically, after 21 hours of wakefulness, the subjects showed a significant improvement in processing speed and working memory from taking creatine. Furthermore, one of the effects of stopping sleep is brain acidification. In this case, creatine acts as a buffer, preventing drops in pH and positively altering the relationship between key metabolites such as phosphocreatine and inorganic phosphate. A discovery that complements the classic 2006 study which already indicated that doses of 20 grams a day for a week mitigated the deterioration in prefrontal cortex tasks and improved mood and balance after 24 hours without sleep. Neuroprotection. As we age, the efficiency of cellular energy production decreases, which is why science is focusing on creatine as an agent. anti aging powerful. Something that is especially focused on women who are in perimenopause and postmenopause, where the protective effect of estrogens has been lost. Of course, there is an important change in the dosage, since while the standard dose is 3-5 g, women over 40 may need between 8 and 10 g/day to see notable improvements in cognitive function and mitigation of hormonal “brain fog.” Furthermore, in women, in addition to improving cognition, there is also an improvement in the quality of muscle mass, which is a critical factor for longevity. Older adults. A systematic review of 2025 and ESCEO studies directly associate creatine consumption with better cognitive health in adults over 60 years of age. In this case, creatine appears to compensate for the natural reduction of phosphocreatine stores in the aging brain, improving sustained attention and reducing mental fatigue. The new paradigm. In this way, science is advancing to see that creatine is not just a matter of gaining muscle, since the brain is also a great consumer of this energy. The reality we have on the table is that creatine is one of the compounds most tested in humans, with an excellent safety profile even at high doses. But in addition to all this, it is also the property that working memory has, since it is undoubtedly the most tangible benefit that we can have in the case of doing complex tasks that require great mental effort under very adverse conditions. Images | HowToGym Sander Sammy In Xataka | We have been obsessed with Japan for decades to understand people who live over 100 years. The key was in Brazil

We thought insomnia was just not being able to sleep. Now we know that there are five different disorders

insomnia is for many people a serious problem with which they deal daily, both day and night, and whose treatment is always based on three pillars: sleep hygienecognitive-behavioral therapy or hypnotic drugs. However, Sometimes what is useful for one person is useless for another.. Something that we now know is because there is not just one type of insomnia, but five. The study. With Spanish origin and published in the Journal of Sleep Research confirms what many specialists were suspecting: insomnia is not a unique disorder. As Francesa Cañellas, from the Son Espases University Hospital, points out, research has proven that there are five different subtypes of insomniaa finding that promises to revolutionize the way we treat sleep problems. Its evolution. The first hypothesis that was raised about the variability of insomnia comes from 2019, when some dutch researchers They already saw that this disorder had five faces. The problem is that these differences had to be proven according to the personality traits and biography of each of the patients. That is exactly what the Spanish team has done. Financed by the Spanish Sleep Society (SES), the study has analyzed data from eight sleep units in Spain using the Insomnia Types Questionnaire (ITQ). Using the patients’ responses in these questionnaires and the data obtained from each one’s sleep, it has been seen that these five profiles are true. Although the problem is that the most severe type is the most common. The different types. The interesting thing about this study is that it does not classify insomnia by the number of hours spent sleeping, but by personality traits or level of distress. Based on this, the classification proposed is the following: Type 1: a very complex group, since their peculiarity is that they have high anguish within them. In this way, they are patients with high levels of neuroticismtension and depression. Type 2: patients who have moderate distress, but who can respond to positive stimuli. In this way, they are able to overcome the problem thanks to cognitive-behavioral therapy, which is the usual standard treatment. Type 3: in this case the patients do not feel much anxiety, but they do have a great insensitivity to pleasure, which is known as anhedonia. This is a problem, because being emotionally flat, conventional treatments are not very effective. Type 4 and 5: They are the mildest forms, since they are due to specific problems in the life of each patient that increase their level of stress but without a psychological burden behind them. The bad news. Although it has been possible to classify insomnia into different types, the reality is that 82% of patients belong to subtypes 1 and 3. These are the ones that respond the worst to treatments and that cause greater psychological damage to people. Logically, these are the people who most frequently go to medical consultations and sleep units because They literally can’t take it anymoresince it is unlikely that a sleeping pill will solve your problem. In fact, the study highlights that these two groups are the ones with the highest consumption of hypnotics and anxiolytics, often with poor results. A precision medicine. The importance of this work lies in the fact that there is no effective standard treatment for insomnia. In this way, if a type 2 patient receives psychological therapy they will do wonderfully, but for a type 3 patient this treatment will do almost nothing. Likewise, type 1 may require a psychiatric approach to treat underlying anxiety and then treat the insomnia problem. With all this, we seek to stop treating the disease in isolation, and conceive that it will be associated with a person who has a specific biography and a personality that may require different care. Images | Solving Healthcare In Xataka | How close (and how far) we are from not sleeping at all: for the first time in history, we have a small way to try it

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