immune

His new promise is based on reinforcing our immune system

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Messenger RNA vaccines (RNM) became known for their role in the fight against COVID. Years after pandemic, this technology is still subject to the interest of the scientific community, not only for its ability to fight viruses but also as a new hope against very different diseases. Diseases such as cancer. A step in the laboratory. Now, an experiment conducted in mice has shown the potential of a new formula against tumors. It is a HRNM -based vaccine capable of boosting the effects of inunotherapy on these rodents. Success is an impulse to a formula that could help us fight various types of cancer. A name, several diseases. We usually see cancer as a disease that can manifest itself in different parts of our body, but the most complex reality. To the point that it is more convenient to understand this disorder as a variety of diseases, each with its characteristics, but also with specific treatments. That is why finding a universal treatment against cancer is even today, a chimera. This vision, Explain the responsible team From this new vaccine potential, it applies to the way in which science seeks new treatments of this type. This can be done well causing these vaccines to focus on a “objective” protein expressed in the cancers of multiple people, well adjusting each formula to specific proteins, present in the tumors of each patient. Third way. The new treatment offers a kind of “third way.” Instead of focusing on proteins of the tumor, what it seeks is to strengthen our immune system, “as if they were going to fight a virus,” says the team. The formula starts from a previous work, in which a team of the same laboratory created an RNM vaccine capable of “reprogram” the immune system to attack glioblastoma (a brain tumor type particularly aggressive). This vaccine was based on a compound adjusted to the characteristics of the patient’s tumor to be treated. The new formula tries to “universalize” this answer. “Promising” results. The results when testing the new vaccine in melanoma mice were “promising” even in cases of tumors generally resistant to treatment. As explained by the team, the new formula combines the RNM formulation with a new drug based on immunotherapy called PD-1 inhibitor. This treatment is a monoclonal antibody that seeks, in Team words “Educate” the immune system to make you think that tuum is an external body to eliminate. The details of the study were Published in an article In the magazine Nature Biomedical Engineering. The new hope of the MNA. HRNM -based vaccines did not stay in the pandemic and have now become an important focus on oncological research. For now they are just a promise: the positive results in preclinical and clinical trials are hopeful but do not guarantee the arrival of new treatments in the short term. Nor do they guarantee the success of these new drugs. In Xataka | The patient who has survived 12 different tumors and hides the “holy grail” of the fight against cancer Image | Tankilevitch polyina

The first fotonic cubal immune to errors is already ready

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The development they have experienced Quantum computers During the last decade it is amazing. This discipline is no longer attractive only for the research centers linked to some of the most prestigious universities on the planet; The governments of the United States, China, Germany, France, Australia, the United Kingdom, India, Canada or Russia are some of those who have openly manifested The strategic character that has for them Quantum computing. However, a good part of the greatest advances that we are as witnesses come from the private company. Google, Intel, Honeywell or IBM are some of the companies that are bidding to make possible the innovations required by the challenges that this computing paradigm has placed in front of us. Experts agree that There is still much to dobut the two greatest challenges that need to be overcome to make the tuning of fully functional quantum compute error correction that guarantees that the results we read are the correct ones, and also the scaling of the number of cubits. In fact, both challenges go hand in hand. Xanadu invites us to tie the future with more optimism than ever Xanadu’s trajectory started in 2016, but what placed this young Canadian company in the center of the debate in early June 2022 was the article published in Nature in which Jonathan Lavoie, his scientific heading, and his team explain how they achieved achieve quantum supremacy. Interestingly, in their project they used a programmable quantonic quantonic processor that they baptized as borealis and is able to operate at ambient temperature. The Lavoie team managed to solve in just 36 microseconds a problem in which a classic supercommer pertrected with the best available algorithm would have invested 9,000 years. However, this is not all. In addition, these researchers assured that their technology had allowed them minimize your hardware imperfections and reach a computational advantage in execution time 50 million times higher than that they have thrown other computers that also resort to photonic quantum processors. Xanadu’s quantonic quantonic processor can be manufactured using the same photolithographic technology used in the production of chips that reside inside our computers and smartphones Whatever the most shocking thing is that at that time, exactly three years ago, Lavoie and his team assured that they intended to be ready before this decade is a quantum computer of a million cubits endowed with the ability to amend their own errors. One of the greatest buzas in favor of the Xanadu scientific team is that its photonic quantum processor can be manufactured using the same photolithographic technology used in the production of the chips that reside inside our computers and smartphones, which opens the door to its mass manufacturing. However, the most interesting thing is the strategy that the team led by Lavoie has devised to make possible the scaling of its quantum hardware until it is able to bring together one million cubits. What he pursues is, in broad strokes, interconnect his quantum processors using a fiber optic network with the purpose of can exchange quantum information and face the same problem in a coordinated way. The most obvious advantage that this approach puts on the table is that, if everything goes as Xanadu researchers have planned, nothing will prevent them from continuing to climb their quantum hardware beyond one million cubits. In any case, these scientists have not wasted time for the past three years. Just a few hours ago they have published an article in Nature in which they describe with great detail the characteristics of their new silicon photonic cubits resistant to errors and integrated into a chip. It is the first time that a team manages to demonstrate the proper functioning of a quantum integrated circuit like this. Very broadly, your strategy is to overlap many photons to encode information in a way resistant to errors. This does not imply that quantum computers endowed with the ability to correct their own mistakes are already ready. To be viable using photonic technology it is necessary Optimize manufacturing and packaging processes with the purpose of mitigating optical losses throughout the platform. Anyway, there is no doubt: this achievement of Xanadu is very important. We will follow the track closely. Image | Xanadu More information | Nature In Xataka | Bitcoin encryption and other cryptocurrencies will fall. And those responsible will be quantum computers

In the middle of the largest commercial chaos, olive oil seems immune thanks to a factor: consumption in Spain

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For months, a fear has persistently toured the oil world. Often fear is undefined, inaccurate, it has no face. This time, on the other hand, it was something clear and easily identifiable: producers feared that, after the crisis of recent years, the olive oil consumption figures They will not recover. Now, the data start drawing an answer. An extremely rational fear. Throughout the last decade, the consumption of olive oil It has been falling year after year. It is not clear why, or what are they Sociodemographic factors that influence; But yes, crisis after crisis (and with the mediation of A deep cultural and gastronomic change), wide layers of the population have gotten out of the oil and the vast majority has not returned. It is evident that in Spain there is a “oil culture” and that, in a sense, makes the Spaniards a “captive public”. We can see it by analyzing the inelasticity of the demand. According to the year dataolive oil has been the product that has most increased this April. It is worth 62% more than last year and 100.4% more than two ago. The demand, on the other hand, only 19.8% fell with respect to the last year and 44.5% compared to two years ago. That is the great trick of the industry and, therefore, the simple idea that this culture is eroding is terrifying for them. And even more in times of change. Not just for The commercial chaos that has caused the tariff vailed of the US, but for The endemic paradoxes of the Spanish oil industry. Do not forget that we talk about a sector that, despite growing 15% every yearis seeing how its productive structure is de -industrialized to forced marches. But Spain has returned. After several bad years, this campaign has finally been the return to normal. That has hehco that prices, little to Cpoco, return to normal. In February, in fact, the year -on -year price had already fallen by 40%. But the good news is another: that demand has grown 48%, According to Nielsen data collected by Cordopolis. Has the curse broken? It is still early to know. In a few months, we can examine in detail how sales go and we can know if consumption levels have really recovered or not. But the sensations are good. And more at a time when, despite everything, the Oleícola sector has managed not to resent with the tariff measures of Donald Trump. For the first time in years, a smile is intuited in the Olivos Sea. Image | Norberto Ortiz In Xataka | The two speeds of the price of olive oil: much more in origin is being reduced than in the supermarket

The benefits of melon on the immune system

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Despite not having the popularity or presence that others fruithe melon It has earned a special place in the tastes of thousands of people thanks to its sweet flavor and its delicate texture that seems to embrace the palate. However, beyond its unique flavor, this fruit, known scientifically as Cucumis Meloalso has great nutrients that benefit the immune system. And thanks to its high vitamin C content, a antioxidant Essential in the production of white blood cells, melon can help fight infections. Likewise, and together with provitamin A, it can improve the body’s defenses by reducing the damage caused by oxidative stress. Melon has significant amounts of vitamins, minerals and antioxidant compounds. Credit: Shutterstock In addition to all of the above, the consumption of melon It can also prevent various diseases thanks to the fact that it strengthens the body’s defensive cells. Other benefits of melon on the human body Belonging to the cucurbitaceae family, the melon It is one of the best options to keep the body hydrated because it is made up of more than 90% of its structure of water. The above also makes the melon in a food that counteracts the effects of dehydration, physical activity as well as other conditions such as fever and diarrhea. Likewise, and thanks to its unique combination of sodium, potassium, calcium and magnesium, the melon It helps maintain the body’s water balance, in addition to promoting recovery. If all of the above were not enough, the melon It is also a great ally in cardiovascular healthsince its regular consumption can help reduce blood pressure due to its potassium content. Melon can also prevent various diseases because it strengthens the body’s defensive cells. Credit: Reform Agency Likewise, and due to the high fiber content it maintains, this fruit has the ability to reduce cholesterol levels in the blood, also preventing the accumulation of fat in the arteries. Melon also provides other benefits to: Renal system: it has a diuretic effect that stimulates the functioning of the kidneys, facilitating the elimination of toxins and waste from the body. Ocular system: it has vitamin A and carotenoids that protect the eyes from diseases such as night blindness and macular degeneration. Digestive system: facilitates intestinal transit and combats constipation due to its high water and fiber content. Continue reading: The key fruit that can improve digestion, according to Harvard experts Elderberry juice could be a “powerful tool” for weight control What fruits can you eat if you are diabetic and which is the best, according to experts

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