colon

colon cancer It is one of the tumors that has increased its incidence the most in young adults over the last few decades, a trend that is very worrying because has made science need to answer why. One of the most important points are the factors that are influencing more and more young people to begin to have tumors in their digestive system. A big problem. Colon cancer is undoubtedly one of the most aggressive diseases that we endure, and also really frequent among the population, with a really aggressive treatment with surgeries that can mean the removal of part of the colonbut also with a high mortality behind them. Its early diagnosis is so relevant that in Spain there are many autonomous communities that have screening programs either screening (although sometimes they fail like in Andalusia) to begin treatment in the case of positive cases, as soon as possible to increase their chances of survival. The problem is that this horrible disease is becoming increasingly prevalent, and science is seeing many factors that are important to take into account to try to reduce the chances of suffering from it. Quantified. This trend has been reflected in a published study in Annals of Internal Medicine which has detected that in many countries the number of cases among those under fifty years of age has grown up to four times faster than in older people. In the end, it is a phenomenon that has revived the debate about the causes and future strategies that must be taken in prevention and early detection. This is extremely important, since a timely diagnosis can mean a big difference in life expectancy who has a patient. The reasons. As stated in the Institute for Cancer Research, London After studying forty-two different countries, two main explanations have been identified. The first is the screening that is done among adults. Although it is very positive to do screening among the population for this disease, the reality is that there is an age limit from which these tests are carried out. This does not occur among the younger population who do not receive this type of screening tests on a regular basis, which may explain the accelerated growth in this group, since cancers are not diagnosed in the early stages. The second reason given is obesity. In this case It is considered a very important risk factor which drives the increased probability of suffering from colon cancer in young people and adults of all ages. Although it remains to be seen if there is an increase in its relationship with the younger population. Environmental factors. In addition to these two causes, the research led by the CNIO Digital Genomics Group in Spain provides new evidence about why this may occur. In his published study In Nature, the influence of the intestinal microbiota, particularly certain strains of E.coli intestinal, producers of the toxin colibactin. As we already sawthis can cause great genetic damage to colon cells that can accelerate tumor development. But other factors associated with the patients’ lifestyle are also being considered. In this case, the increase in type 2 diabetesespecially when there is a sedentary habit and unhealthy diets that seem to increase the risk of having this type of cancer. A Swedish study with a national cohort showed that people with diabetes reach an equivalent risk of colorectal cancer at younger ages than those who do not suffer from it, requiring prevention and monitoring before the standard screening age in the general population. But ultra-processed diets also come in here, excessive consumption of alcohol or even sugary drinkswhich can be an important risk factor. Prevention. Experts agree that there is no single and definitive cause, but rather a combination of genetic, biological, environmental and social factors. While research continues, it is proposed to implement comprehensive prevention policies that adapt to these realities. To do this, they aim to apply personalized screening that includes risk factors such as obesity, diabetes or family history. But we must also focus on research into how our microbiota can have an important implication in this. This forces us to have to take great care of what we eat and maintain adequate intestinal health. But the most relevant thing is to adapt the recommendations for starting screening for high-risk groups, such as young people who have diabetes or a family history so that they begin surveillance at age 40. Images | Ramon Inciarte Julia Koblitz In Xataka | Until now, different types of cancer required different types of treatment. A new vaccine wants to change that