aging

There is a ‘good’ fat that hides a secret to aging better and being fit. It only remains to get the pill

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Aging is inevitable, and with it it comes A progressive loss of physical capacity that causes it to be more difficult to walk or stand up. This makes Stay fit It becomes much more difficult and therefore the resistance begins to decline. But … what if this decline can be slow down? This is precisely what science is focused on. Fat as anti -aging. Researchers at the Rigers New Jersey Medical School They have discovered That a special type of adipose tissue, known as brown fat, could be the key not only for healthier old age, but also Improve physical performance. A study of great relevance, since it can open a new route in the anti -aging field. The team that has led this research has been able to identify an unusually powerful form of this ‘good fat’ in mice, which not only Increased his life expectancybut improved its exercise capacity by an impressive 30%. Now, the race has begun to be able to replicate these same effects in humans through a drug. Not all fat is bad. When we think of fat, the White fat or white adipose tissue. Its main function is to store excess calories in the form of triglycerides and is the one that can bother us aesthetically throughout our lives. Although in essence it is a large energy deposit. But, nevertheless, there is another type of fat that is much more interesting: brown fat or Brown adipose tissue. Unlike white, brown fat is specialized in burning calories to generate heat in a process called thermogenesis. This is possible thanks to the fact that their cells are full of mitochondria, which are the organelles that act as cellular power plants and that give it its characteristic brown color. In our life where we have more fatty fat in our body is when we are babies, since here it is crucial for Keep body temperature. But when we grow, the brown fat is lost until some cracks are around the neck and shoulders. But here the white fat is the one that dominates our body completely. One step further. Knowledge about brown fat already has a long journey in scientific literature. But it is now when this study goes further to point that it is linked to having a healthier longevity and with a much more appropriate physical exercise. How they knew it. To get to this conclusion, the researchers worked with a genetically modified mouse model to lack a protein called RGS14. The mice without this protein lived approximately 20% than their normal partners, and curiously the females lived more than the males in a pattern similar to that followed by humans. Even at the advanced ages, these mice avoided the typical signs of aging such as body atrophy, hair loss or the graying of the fur. But it does not stay here, since when submitting them to physical tests, the modified mice showed a 30% higher performance, both in distance traveled and in resistance. And all this because mice without RGS14 developed a dense and powerful brown fat than who expressed the protein correctly. The definitive test. To confirm that it was brown fat, and not another effect of genetic modification, scientists conducted a crucial experiment: transplanting the brown ‘supergras’ of mice without RGS14 to normal and healthy mice. The results were overwhelming. The mice that received this transplant improved their ability to exercise in just three days. On the other hand, when brown fat was transplanted from a normal mouse to another, an improvement was also observed, but much more and with eight weeks ahead to manifest its effects. Something that showed that the fat of the genetically modified mice was exceptionally powerful. Because? The mechanism seems to reside in an improvement in blood circulation. The indications suggest that brown fat promotes the creation of new blood cases in the muscles that improves the flow of blood and oxygen during exercise. The goal. Research suggests that this brown fat not only improves physical performance, but also protects against a series of ailments associated with age, such as obesity, diabetes, cardiovascular disorders and even cancer and Alzheimer’s. Vatner’s team is already working with collaborators to develop a drug that imitates the effects of this powerful brown fat, hoping to have a compound ready to be tested in approximately one year. But the idea is not only to increase life expectancy, but “healthy life expectancy.” That is, even if you live longer, these ‘extra’ years enjoy good physical and mental health. While we expect that future pill, there are techniques such as deliberate exposure to cold (the famous ice baths) that can naturally increase our brown fat levels. However, as Vatner points out, most people would prefer to take a pill to take an ice cream bath. Images | Tatiana Zanon In Xataka | Our brain has its own backup. It is already known how to create copies in parallel of each memory

In an increasingly aging country to become old, it is a condemnation of poverty

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G. Young Soo has done everything reasonably well In life. At least in work. At 23, she began working as a office worker in an insurance company and throughout the last three and a half decades, she has gradually climbing in the organization chart, through the positions of a branch director and team leader in several departments. Now, with 59 years, his future is quite black: his salary has been trimming during the last five years until he stayed in the middle of what he charged at 55 and in a few months, when he reached 60, he will have to leave his post. It is not that Young Soo has angry at its bosses or that has been accommodated after 36 years of loyal service. No. His employment situation is explained simply and plainly by the complex (and controversial) Employment Laws of South Korea based on age. “Alone on a road with curves”. Young Soo is a pseudonym, but its history is real and reflects the situation in which many South Korean workers are about to turn 60. We know it because it is one of the 34 employees in the country Interviewees By Human Rights Watch (HRW) to know the work overview (and vital) they face. All share several characteristics: they are between 42 and 72, they work in Seoul (some in the public sector, others in private companies) and will have to deal with the country’s labor policies. Their stories often go along the same lines as G. Young Soo: after years (or even decades) of work their professional/financial/vital perspectives darken as they approach their sixty birthday. Another similar case is that of Young Sook, 59 too and that has been working as a nurse for almost four decades. At 60 he will have to retire, yes or yes, a perspective that causes authentic unease. “I can’t imagine outside this organization”, confesses The woman during her talk with HRW. “It would be like being alone on a road with curves.” “Punished for aging”. His stories are part of A report of 72 pages in which HRW warns of the serious consequences that Corea’s laws and policies have for the oldest population. The document is so critical that its tone already advances in the same title: “Punished for aging”. It may seem exaggerated, but the analysis indicates that the country’s regulations often end up condemning its elders to a gradual loss of purchasing power, worse quality jobs, low remuneration and undercurred mental health. “The laws and policies of South Korea to protect older workers from age discrimination actually have the opposite effect,” Bridget Sleap warnsHRW researcher. “They deny older workers the opportunity to continue working on their main jobs, they are paid less and force them to accept precarious jobs and with lower salaries, all simply because of their age. The government should stop punishing workers just to age.” In your report there is an idea that slides several times: “Remove Ageism“ A percentage: 38%. The report of HRW not only exposes specific cases. It also slides some figures and percentages that help to better understand the situation that the elders live in the country. According to the data it manages, in 2023 the relative poverty rate among people of 65 or more years was 38%, The worst result of the countries that make up the OECD. In practice, that means that almost four out of ten elders have 50% (or less) of the national average income, which in 2023 stood at approximately $ 28,200. HRW quotes another report that reveals that the average monthly salary of 60 or more years were 29% lower than their younger colleagues. The percentage is not too surprising if we take into account two factors. The first is that in the country there is a system that allows to reduce wages in the years before retirement. The second, that 69% of people over 60 who worked in 2023 did it in precarious jobs. If we talk about the South Korean population as a whole, that data does not reach 40%. A problem with three legs. The big question arriving at this point is … Why are so many older ones attached to that situation? Although there are many factors at stake, there are three keys, three laws or labor policies based on age for HRW. The first is the mandatory retirement age. South Korean legislation is fixed from the age of 60, which means that companies can force a work to retire when they are fulfilled. No need to claim more reasons. They are the companies those that decide whether or not they set a retirement age, but the measure is widespread. Both in the public sector and among private companies. Especially in organizations of more than 300 employees. According to the South Korean Ministry of Labor, they accept that possibility 95% of companies With that last profile, signatures that usually set forced retirement in the 60 years. Among small businesses it is not so normal. In the country I already has opened the debate on the need to rethink (and increase) retirement age. In fact, President Lee Jae Myung has committed to approximately 65 years old, but HRW’s study slides that the key is not when the elderly are withdrawn, but how they do it. The maximum salary rule. The other standard that HRW quotes is the “maximum salary” system, which marks the last years of the elderly in its companies. “It allows employers to reduce workers’ salaries during the three or five years prior to their mandatory retirement,” says the agency, recalling that this practice “causes financial and psychological damage” to those affected, in addition to “based on a discriminatory stereotype.” Without counting on its impact on the quotes, compensation for dismissal or unemployment payments. And why does that system apply? The initial idea was to reduce the cost of hiring major personnel in a salary system based on antiquity and at the same time favor the creation of … Read more

The aging of the population and a poor pension system has a new symbol in Japan: grandmothers are rented

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During the last months, the great drag crisis Japan with the aging of its population has been expressed in multiple formats. For example, in the field they are becoming Schools in hotels And more and more elderly for living in jail. In fact, the situation is such that the shortage of young labor has turned retirement into an aspiration of the past, with a large group of over 70 years keeping your work life Active The latest: the nation has begun to rent grandmothers. Grandmother for hours. As we said, in the context of a society that ages quickly and where loneliness and isolation They have become structural phenomena, Japan has witnessed the emergence of a unique and deeply revealing service: Ok obaachanan initiative that allows rent grandmothers For hours to fulfill as varied functions as teaching to cook, take care of children, accompany a loving break or simply provide emotional support. Behind this phenomenon, which might seem picturesque at first sight, underlies a series of economic tensions and social that clearly draw the fragility of the social contract in the Third Japanese age. With More than 9.3 million of people over 65 years old still active (That is, one in four elders continues to work after retirement age), many are forced to seek new forms of income against pensions that are barely enough to meet basic needs. For these older women, OK Obaachan represents not only an economic way, but also a form of Keep feeling usefulpresent and linked to society. A human catalog. The service, offered by the Client Partners companyis presented as a multifunctional female personnel (a kind of task and company company) and offers grandmothers to a cost of 3,300 yen per hour (More transport). The current template includes about 100 women between 60 and 94 yearswith diverse profiles and skills that cover From the kitchen, calligraphic writing or family mediation, to the simple ability to listen, advise or do affective presence. What began as a practical project has become an experience deeply human: Some grandmothers accompany people who want to leave the closet in front of their parents, others participate in academic research on social evolution in Japan, and there are those who simply help cope with everyday life. Some of the “rental grandmothers” Grandmothers of all colors. He Customer profile It is as wide as that of the grandmothers themselves: young people without family, lonely adults, people looking for a maternal figure, or even couples in the process of rupture that require a conciliatory presence. The range of services covers from functional to emotional, and in many cases the symbolic. Social reactions. What’s doubt, the appearance of the service has generated reactions found In Japanese society. While some value the possibility of receiving advice and affection from an experienced person, others express discomfort Before commercialization of human ties. In fact, they have appeared comments on networks social ranging from praise to the idea of ​​”feeling needy” to irony about the physical risk for the elderly or even the complaint about the lack of an equivalent service for men. Because, in effect, ok obaachan is exclusively feminineboth in its template and in its parallel services of “rental friends” or “rental relatives”, all managed by a company that It is defined as “Manitas company only for women.” They counted the media premises that, although there is a male version called Ossan Rental (Centered on middle -aged men, between 30 or 40 years), its approach is different and more informal, and does not reach the level of visibility or sophistication of the service focused on grandmothers. Grandmothers as a symptom. The proliferation of this type of services cannot be analyzed without attending the demographic backdrop that makes them possible. We have gone counting: Japan is one of the countries more aged of the world, with an inverted population pyramid, rates of minimal birth rate and a longevity that exceeds 85 years on average. Traditional family structures are They have eroded: Unipersonal households They multiplyintergenerational links They weakenand community fabric It is fragmented. In this scenario, older people not only face economic uncertainty, but also an existential vacuum. Initiatives like OK Obaachan They workas well as a kind of emotional economy, in which rent affection (either On the contrary), listening and the human heat that was previously given in the family. Far from being a marginal curiosity, the phenomenon embodies an adaptive response (and, of course, commercial) to a deeply structural need. Radiography of the present. If you want, although the boom Ok obaachan Point to the endearing, functional or even ingenious, deep down it is a sign of cultural transformation. The figure of the grandmother, traditionally associated with the home, the transmission of values ​​or the emotional refuge, has become a professionalized resourcenegotiable and temporal. What was previously free and spontaneous is now organized, is invoiced and reserved for hours. A RARE Av of professionalization of tenderness that speaks both of the spirit of resilience of older women and the void left by a Hyperravalized societywhere every need (even affective) must be covered For a transaction. Japan, as in so many Other trendsit is possible that anticipating a phenomenon that could be reproduced in other industrialized societies. In an increasingly individualistic world and agedperhaps the question is not why there is a grandmothers service for rent, but why the hell we need so much. Image | Miki YoshihitoClient Partners In Xataka | The aging of the population in the field has taken Japan to an unprecedented proposal: converting schools into hotels In Xataka | The aging of the population is causing Japan to make an unprecedented decision: welcome digital nomads

How simple gestures tell us how good we are aging

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In recent days, various media They have echoed of The statements what he did in his podcast Peter Attia, expert in longevity. In your program, The Peter Attia Drivethe toilet explained that a man between 40 and 50 years should be able to load his own weight (75% of his weight in the case of women) distributed between his two hands and walk for a minute. This raises a curious doubt: what does our grip force With longevity? Well, although it may seem surprising, our grip strength can tell us a lot about how we are aging. Several studies published in recent years seem to confirm this relationship, turning the grip force into an important biomarker linked to healthy aging. “People with better grip force age more slowly. Having a good grip force can slow down the immunosenescence process, or the deterioration of your immune defense associated with age,” Ardeshir Hashmi explainsdoctor at Cleveland Clinic. “You can also improve your ability to recover of diseases, or homeostenesis. Finally, it can prevent fragility. “ The lack of grip force is, for this expert, not only indicator of a faster aging, also a sign of a higher risk of chronic and even a lower life expectancy. Scientific literature seems to secondary this relationship. A study Published this year in the magazine Scientific ReportsIt is a good example of this. The study analyzed a population of 1,446 agent participants between 50 and 90 years of age, the majority (1,095) women. The team measured the grip force of each participant, who also filled a survey focused on estimate your quality of life. The team found a significant relationship between grip and the general evaluation of the level of quality of life. Another recent studypublished in 2023 in the magazine Journal of Cachexia, Sarcopenia and MuscleHe used biological watches to study the relationship between grip and aging force. Biological watches are different biomarkers that indicate to what extent or what rhythm our body ages beyond our standard chronological age. The study responsible for the study also found an inverse relationship between aging, measured through markers of the DNA methylationand the grip force. In other words: people with greater force of grip tend to age more slowly as observed in this study. Posted in the same magazine, but a year earlier, Another study He found that the little grip force was associated with a major risk of dementia Already greater mortality. This taking into account associated factors that could lead to establishing the relationship. These are some of the recent examples found in the literature. In 2019, A review of literature Published in the magazine Clinical interventions in aging He had already found, in previous analysis, evidence of the link between the grip force and health, through factors as varied as general strength, density of bone minerals, fractures, malnutrition, cognitive impediments, diabetes, depression or quality of life, among others. Remedying loss Some doctors, such as Dr. Hashmi recommend exercise to avoid the loss of this grip force, a loss associated with the age that tends to begin around the age of 50. According to hashmithis can be as simple as squeezing a ball (such as the classic antiestrés balls) for at least 10 minutes and twice a day. This without forgetting Conventional exercises that can help us to keep ourselves in form in more advanced ages. Although the recommendation to exercise and lead an active life is never more, it should be noted that the relationship between the grip force and our welfare and longevity is complex. Correlation does not always imply a direct cause ratio. For example, grip force can perfectly be correlated with our general health status. People who exercise will probably have greater grip force and also a better state of health. In addition, we know some forms of dementia and neurological diseases such as scleriosis not only reduce our quality of life, but also They affect our mobility and our ability to handle and develop when it comes to doing so. In Xataka | Preventing is better than healing: why keep doing sports in adulthood can save us a scare with hypertension Image | RDNE Stock Project

Japan has encountered a problem with the aging of their growing foreign community: they cannot bury them

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Japan and their society have been immersed in a process of transformation where the role of “foreigner” every time It is more important. Waves arrive in the country, and in many cases to stay. The clearest example is giving with many Chinese who They arrive not to returnbut it is exponential to all nations. This is resulting in the population of advanced foreign residents is increasing, and with it, of deaths. A problem that nobody saw. I told this one Nikkei weekend. Foreign residents in Japan are dealing with serious difficulties in burying their loved ones. The reason? The Cremation predominancewhich has become the norm in the country. He 99.99% of the deceased In Japan they are cremated, according to the Ministry of Health, Labor and Welfare, which leaves those who require burial for religious reasons or simply by tradition with very few options. The problem is especially critical for Muslim and Christian communitieswhich consider unacceptable cremation. The situation is aggravated as the foreign population ages and grows the demand for burial spaces, which has turned the issue into an increasingly urgent challenge for the nation. Examples of a crisis. In the medium report they had a case that occurred last January after the death of A Pakistani man in Kanagawa which unleashed a frantic search for a cemetery that allowed its burial. His family, with limited resources, could not repatriate his body, and after multiple rejections and high costs, they finally managed to bury him in the Cemetery Honojo Kodama in Saitama, for a amount of 300,000 yen (around 2,000 euros), paid by friends of the community. There are more similar cases that are repeated throughout the country. For example, that of a Korean Christian woman 80 years old who died in October, and his son took a month and a half to find a burial site. During that time, his body had to be stored in a police installation. Factors that hinder burials. There are several keys to understanding the controversy around the shortage of cemeteries that allow burials. The first one already said: the predominance of cremation. Japan has gone from burying their dead to incinerate them almost entirely in the last 50 years. In 1913, only 31% of the deceased were cremated, but by 1934 it had already become the majority practice due to health concerns and lack of space. But there is more. Another problem is derived from The scarcity of landsince the large amount of land necessary for cemeteries in a country with limited space is a key obstacle. Also the Environmental concernssince there is fear that burials contaminating groundwater (although there is no clear evidence that supports said statement). Finally, it points to the local community resistancesince in many regions residents oppose the construction of new cemeteries, which has frustrated several projects. The aging of the “foreigners” and the future impact. Japan currently houses 3.41 million foreign residentsof which 220,000 are 65 years or older, an increase of 150% in the last decade. The aging of this population implies that the demand for burials will only grow in the coming years. In this regard, Professor Hirofumi Tanada, an expert in the Muslim community in Japan, estimates that there are around 350,000 Muslims in the countryfacing problems similar to those of other religious minorities. Tanada warned that in 10 or 15 years could be even more difficult Find places of burial, which will intensify the crisis. Regional disparity in the availability of cemeteries. Another of the problems of the problem. Japan presents strong regional inequalities In access to cemeteries. Namely: while in the Kanto region (which includes Tokyo and its surroundings) there are four private cemeteries that allow burials, in regions such as Tohoku and Kyushu have none. Again: despite the growing need, the efforts to create new cemeteries have found obstacles. Last December, the governor of Miyagi proposed to build a cemetery in the region, but received an avalanche of calls and emails from Citizens expressing your opposition. The attempt of a Muslim cemetery. It happened in 2018when the Beppu Muslim Association in Oita Prefecture tried to build a cemetery in the town of Hiji. After seven years of negotiations, they finally agreed with local authorities and residents to build the cemetery in municipal land, with conditions such as the limitation of the use of the cemetery to residents of Kyushu and a regular monitoring of water quality. However, The project was canceled When a new mayor revoked the sale of the land, citing environmental concerns. This left the Muslim community without viable options in the region. Proposals and barriers for a solution. Professor Khan Muhammad Tahir Abbas, director of the Beppu Muslim Association, told that the lack of cemeteries not only affects foreigners, but also Naturalized Japanese and converts to Islam or Christianity. Since 2021, requests have been presented to the Ministry of Social Welfare requesting the creation of adequate cemeteries for religious minorities. However, to date, Japan has not adopted No clear policy about itarguing that differences in customs and beliefs make it difficult to implement a standard solution. Meanwhile, other countries have managed to integrate religious burials into their funeral infrastructure. In Norway, the United States, Canada or Singapore, among others, specific sections have been designated in public cemeteries for Muslims and other religious minorities. A challenge that the nation cannot ignore. With the Foreign resident figures In hand, Japan is facing a problem that cannot be ignored. The lack of accessible cemeteries For this group it is a challenge that will only be aggravated over time. Although the cremation remains the norm, the aging of the foreign community demands a more inclusive answer by the Japanese government. As They explained in Nikkeiif the nation wants to fulfill its objective of being a more diverse and cozy society, it should facilitate solutions that allow religious minorities to bury their dead with dignity. This requires overcoming the local opposition, adapting funeral policies and developing adequate infrastructure, as other nations with … Read more

The 3 assets with which you can increase the anti -aging power of retinol

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Practicing self -care is one of the eight purposes that a Swiss welfare guru proposes to completely transform our life: it gives us the best excuse to book a few minutes a day during which to relax and, increasing, increase self -esteem. Notice progressively prettier, bright, firm and smoothed skin It has a lot to do with this last benefit, for which to have effective beauty assets is key; Among the most powerful, the Retinol, a derivative of vitamin A widely used in cosmetics for its smoothing properties of wrinkles, texture and enhancers of firmness. Although powerful by itself, when combined with other ingredients multiplies its strength. Designing the beauty ritual in such a way that the ingredients of each cosmetic are enhanced with each other is the secret of the most radiant skins and the good news is that experts have revealed the perfect cocktail for a superactive as interesting as retinol. We anticipate that Your natural allies are three: Vitamin C, peptides and hydroxyacids. © Getty Images Retinol’s anti -wrinkle power Cleaning, applying a tonic, treating specific problems with ultraconcentrated formulas in assets, hydrating and protecting during the day with a sunscreen: these are the main steps of a good skin care routine and the third is in which it is usually come in At stinol serum -shaped retinol with which to smooth the wrinkles, improve the texture or reduce the appearance of the spots. “Thanks to its regenerative capacity and its proven effectiveness, Retinoids are considered the anti -aging gold standard “says Estefanía Nieto, dermocosmetic director of Medik8, on an ingredient that further increases its capabilities when playing as a team. Crystal Retinal 24, from Mediak8 (135 euros). Capture Totale Retishot, of Dior (115 euros). High Potancy Growth Factor Firming & Lifting Serum, by Perricone MD (147 euros). Unicretinol ++ Invisible Night Mask, by Unicskin (95 euros). In order for all their benefits to be clear, Raquel González, Cosmetologist and Technical Director of Perricone MD, reminds us that “at the cosmetic level, it is the gold standard in the regeneration of the skin. antioxidant, promotes collagen and elastin synthesis, swelling the tissue In the long run and reveals a more juicy and smooth skin. It is the most effective known ingredient in this regard. “In short, it seems unstoppable on its own, although when it really displays its magic it is when combining it with the three assets that we anticipated above. Vitamin C, the illuminating supering picture Brighting Sprouts Ecstasy, from Byoode (55 euros). Vitamin C Esther Photo Bright Moisturizer Broad Spectrum SPF30 (82 euros). “To take the results of the retinoids to the next level, it is necessary to accompany it from other assets, such as vitamin C, peptides and hydroxyacids,” says Raquel González; Three master mixtures that drive their benefits. The cosmetologist of Byoode, Lara González, begins with the advantages of Vitamin C: “In the morning it has antioxidant functionsince it protects the skin of free radicals and oxidative stress. However, At night it is more regenerative and helps to unify the tone “. And it is precisely at the last minute when it has to be combined with retinol, “there are even cosmetics that have vitamin C and retinoids in their formulation as proof that together they are better and enhance their effects, since they support the renovating functions,” adds Estefanía Grandson. Peptides, fashion assets Blue Diamond Super Cream, from Omorovicza (413 euros). Snow Lotus Lifting Cream, Boutijour (64 euros). Since Hailey Bieber formulated many of the products of his brand, Rhode, with this cosmetic ingredient, has become one of the most popular and the best thing is that beyond a passenger fashion the peptides have more than spare reasons to star in The beauty rituals. As Marta Agustí, Dermocosmetic Director of Omorovicza points out, “in general, peptides are chains of amino acids who work ordering the skin to synthesize collagen and elastin, keeping the skin youngestwith less wrinkles and greater firmness, also enhancing luminosity. ” As for the reasons why they work so well with the retinoids, Raquel González justifies it with that as “They help to regenerate and repair the skin, allow the possible irritating effects to be tolerated better of retinol at the beginning, such as dryness or initial redness. In addition, by stimulating collagen and elastin synthesis, they work in synergy with retinol to enhance the reaffirming and regenerative effects. ” Hydroxy acids, a powerful regenerator Gold Perfection22 Mask, from Ambari (115 euros). Adzuki & Ragi Fantasy, from Byoode (39 euros). Finally we look at acids that with great renovating power: “By applying between two and three times a week hydroxyacids such as glycolic, lactic or gluconolactoneIt is more than enough, “says Isabel Reverte, Dermocosmetic director of Ambari. On her idyll with retinol, the expert reveals that “they are ideal to combine with retinoids, since they prepare the skin and enhance their regenerative results. Of course, yes, It is essential not to use them at the same time To avoid possible irritations. “Finally, Byoode’s cosmetologist says that” they should only be used with more caution if we are starting with retinol and we have the most sensitive skin. ” (tagstotranslate) Anti -aging

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