withdrawn

Last December, the team led by the prestigious researcher Mariano Barbacid filled the headlines of the main media with great news: had found a triple therapy to eliminate pancreatic tumors in animal models. Very relevant news because of how deadly pancreatic cancer is and how it affects our society, but now this euphoria has hit a wall after the decision of the US National Academy of Sciences to remove the item from PNAS magazine. The context. The original article, published on December 2 of last year, was not just another publication, but described the results of administering three drugs in 45 mice who had pancreatic cancer. And although it was a preclinical study that had not been tested in humans and was the expected next step, it generated great expectation. The promise of a cure, even if it was in the animal phase, propelled intense fundraising campaigns to be able to start a clinical trial with humans as soon as possible. In this way, foundations such as CRIS against cancer achieved raise 3.7 million euros in the heat of these advances and thanks to the media showcase that was given to them. And now they withdraw it. The first thing to keep in mind when faced with so many alarmist headlines is that it is not removed from the PNAS magazine because the results have been invented or exaggerated, but rather the reason lies in the omission of important information regarding to conflict of interest. In this case Mariano Barbacid, taking advantage of his status as a member of the National Academy of Sciences of the United States, used a “fast track” of publication that is reserved for academics of this institution. The problem is that this privilege requires scrupulous and impeccable transparency. Data omission. As detailed by El Paísthe alarms went off in February 2026, when the academy received notices about possible conflicts of interest that have now led to the sudden retraction of the article. The problem is that Mariano Barbacid, along with researchers Carmen Guerra and Vasiliki Liaki, are co-owners of Vega Oncotargetsa spin-off which was born in the ecosystem of the National Cancer Research Center (CNIO) with the aim of developing and marketing therapies against pancreatic cancer like this one. This is why informing the journal that the authors had a direct economic and business interest in the success of the study is a violation of the most basic transparency regulations in scientific publication. It always happens. When a researcher wants to publish the results of his or her research, a lot of data must always be provided, both about the method that has been followed and everything behind it, such as the source of financing or the conflicts behind. For example, if a researcher owns shares of a large pharmaceutical company and studies one of its drugs, logically good results will benefit him because the value of the company will increase. And this is something that should always be reported so that anyone reading the research knows if the researcher may have been influenced by an economic component. And in this particular case, the fact that there is already a company that will commercialize the future therapy that is being investigated is logically something that must always be specified, because if the study goes well, it logically benefits the company enormously. There are already answers. As we say, PNAS sanctions bad practice when it comes to being transparent, but in no case does it indicate that the research is poorly done. Along these lines, Carmen Guerra has already admitted the error, as El País points out, and has confirmed that the team has resubmitted the article with this correction, detailing that they do have participation in Vega Oncatargerts. The problem is that now they are going to have to go through the entire standard review process and the republishing will not be fast. Images | UPV brgfx on Freepik In Xataka | Mice today, hope tomorrow: researchers have managed to attack pancreatic cancer before it forms