Our brain has two different circuits for laughing, and one of them is ancestral

Laughter seems like a simple and automatic act, but neurologically it is a enormously complex phenomenon. It is so complex that we have different types of laughter, since almost all of us have noticed the difference between that uncontrollable laughter that leaves us breathless and the polite laughter that we let out out of courtesy. Now, science suggests that laughter does not depend on a single circuit, but on at least two partially separate networks: one more linked to spontaneous and emotional laughter, and another to voluntary or social laughter. A question of evolution. This has been the focus of an interesting investigation published in Trends in Neurosciences that pointed out that we live with an “ancestral laugh” that is deeply emotional and is directly related to other primates. But, on the other hand, we have “human laughter” which is involuntary and intended to “look good.” To get to this point, the researchers analyzed dozens of patients to whom they performed electrical stimulation while they were awake in order to see the areas of the brain that ‘lighted up’ when they began to laugh. Two networks. The most technical results pointed to the existence of two brain circuits for laughter. The network of spontaneous laughter, which is ancestral, is activated when we hear a brilliant joke or when we are tickled. It is involuntary and purely emotional, causing the most primitive brain regions linked to the reward system and emotions to become active, such as the nucleus accumbens. On the other hand, the laughter that we emit voluntarily to join a conversation and show empathy activates a circuit that does not depend on emotions, but on motor and cognitive control. Two functions that are much superior on the phylogenetic scale of our species. In the disease. This division, which was already intuited in classic reviews, explains why some neurological diseases can nullify the ability to laugh at will, but keep spontaneous laughter intact, since it is in totally different places. With our ancestors. If voluntary laughter appears to be a sophisticated social tool developed by the Homo sapiens To complement language, spontaneous laughter is a direct echo of our evolutionary past. And to understand where this primal laughter comes from, a recent study published in Communications Biology analyzed the acoustics and rhythm of laughter with the aim of comparing laughter sequences in humans and great apes, demonstrating that there is a shared rhythmic pattern. In this way, when a chimpanzee or a bonobo is tickled, it emits vocalizations whose rhythm and timing bear a striking similarity to the spontaneous laughter of humans, or even the laughter of babies. Its meaning. This finding suggests an undeniable evolutionary continuity, since laughter did not appear out of nowhere in our species, but rather arose from neural and vocal networks that our hominid ancestors already possessed. Over hundreds of thousands of years, as our brains developed the motor and cognitive areas necessary for complex language, we “hijacked” that emotional vocalization to create a second circuit: controllable, voluntary, conversational laughter. A missing link. Discovering that laughter has a rhythmic “barcode” shared with apes and two distinct brain pathways is not just a biological curiosity. As points out Nature News Echoing these findings, understanding the evolution of laughter is a direct window into the evolution of vocal control. And the ability to fake a laugh or emit it voluntarily at the exact moment of a conversation requires immense brain plasticity. That is why understanding how we went from the involuntary gasps of primates to the subtle human laughter could be one of the master keys we have in our hands: how we have been able to develop the language we use today. Images | OurWhisky Foundation In Xataka | The human being is the primate that sleeps the least. Science is clear that it is a “radical evolutionary experiment”

The story of such an unusable approach that years passed by being the laughing of chemistry

Being a student, Susumu Kitagawa read a book that spoke of an old Chinese philosopher, Zhuangzi, who defended that we must question everything we believe useless. Even if you do not contribute an immediate benefit (or we cannot see it), that does not mean that it is not valuable. Kitagawa was able to devote himself to that idea in any field of human activity. But, as the book was from the Japanese physicist (and Nobel) Hideki Yudaka, he decided to devote himself to basic science. The most useless among the useless. What is the point of working on something like that? In 92, when he presented his first molecular construction, the truth is that his work honored that uselessness: “A two -dimensional material with cavities where acetone molecules could be hidden.” The curious thing, however, is that “he used copper ions united together by larger molecules” such as pieces of a puzzle. The curious thing for us now, of course. In the first half of the 90s, no one made the slightest case. Kitagawa I wanted to continue working With this type of materials, but the answer (again and again) was always the same: No. in the following years, each and every one of the aid he asked for were denied. He, of course, did not give up. Not even when in 97 he created a stable material (capable of absorbing and releasing methane, nitrogen and oxygen without changing shape) luck smiled at him: nobody saw his appeal. Not that they were wrong, but there were already better things. What sense did it have to continue working on something like that? The desire not to need ‘luck’ The answer to that I had Omar Yaghi. In that same year 1992, Yaghi achieved his great research project under the premise that “the traditional way to build new molecules was too unpredictable.” Until that time, chemicals were dedicated to putting things in a bowl, heat them and see what happened. Yaghi aspired to find more controlled ways of creating materials. Jordano’s team began to obtain good results when he began combining metal ions with organic molecules. They had found, so to speak, their Lego pieces: the elements that kept together and stable the most diverse molecules. Are you familiar? It was just the same approach that, independently, had launched Kitagawa. And yes, indeed, nobody thought it was something very useful. At least, it did not generate very useful things. Back to the origins Then, both Kitagawa and Yaghi were traced background for this new way of chemistry. There they met A speculative article Published in 89 by the journal of the American Chemical Society. The author, Richard Robson, worked in Australia and had been spinning all this since 1974. In those years, Robson He was in charge of converting wood balls into “atomic models” with which students could create molecular structures and familiarize themselves with the world of chemistry. To do this, he asked the university workshop to pierce holes in the balls. In this way, thanks to wooden rods (chemical bonds) atoms could be built. Immediately, Robson realized that the holes could not be placed at random. Each atom, forms chemical links in a specific way and, if I wanted to do the realistic model, needed to mark where the holes should be drilled. That is what gave him the track: in the position of the links there was an incredible amount of information. Moreover, those links hid the key to building new molecular structures easily and easily. Three ways to reach the same way of building the world Johan Jarnestad/Royal Swedish Academy of Sciences Metalorganic structures (which are called this type of structures) They serve almost everything: Capture carbon dioxide, separate water PFAS, administer drugs to the body or manage extremely toxic gases. Some may catch the ethylene gas from the fruit (to mature more slowly); Others may encapsulate enzymes that break down the remains of antibiotics in the environment. That is, we talk about one of the most versatile technologies of today and, for years, they were something completely useless. What he said before: pure basic science. An uselessness so enormous that the world can change. Image | Boasap (modified) In Xataka | The “Curse of the Nobel” not only affects the authors: also the publishers who publish them suffer their effects

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