fragility

Aging brings with it a series of inevitable tolls, and one of the most limiting is loss of muscle mass and strengthwhich is a problem known as sarcopenia. This can cause a person to not be able to move comfortably around their home, causing them to have significant limitations in their daily lives. But now we have seen that there is a compound in garlic that can help us delay this agingalthough without being magical. A new study. Now, a promising new study published in the prestigious magazine Cell Metabolism has identified a specific compound derived from garlic that improves age-related muscle function. But we must keep in mind that we are not talking about the raw garlic that we add to the pan and which for many has a horrible taste, but rather about a very particular metabolite present in the aged garlic extract. The protagonist. This study focuses specifically on S-1-propenyl-L-cysteine ​​(S1PC), which is one of the metabolites that is generated during the aging process of garlic. This is where we can find a little help to delay aging. But it is essential to avoid the promises of “anti-aging elixir”, since eating raw garlic daily will not provide you with the necessary doses of this compound to replicate the results. Furthermore, it must be taken into account that it is not a “cure against old age”, but rather a solid therapeutic target to combat muscle fragility and sarcopenia. A surprising connection. The most fascinating thing about the study is not only what S1PC does, but how it does it, since when ingested it directly activates an enzyme called LKB1 that encourages adipose tissue to secrete a key protein called eNAMPT into the bloodstream. This protein is essential, since when it reaches the brain it acts on the regulatory centers of systemic metabolism and causes nervous and chemical signals to be sent from the brain that drastically improve the function of skeletal muscle tissue. Just what we want to improve in aging. Your results. To verify that this mechanism really works, the researchers carried out tests in both animal models and humans. Here, aged mice, after being administered the metabolite S1PC, improved their muscle strength and reduced markers of frailty related to aging. In the case of humans, the team conducted a human clinical trial using aged garlic extract, and the results confirmed that consumption of this compound raises the levels of eNAMPT that we have discussed before. But the most interesting thing is that the effect is greater in those people with enough body fat, which makes sense, since this protein is released by the adipose tissue itself. Images | wirestock at Magnific In Xataka | It is possible to convince an AI that shoving garlic up your ass is a good idea. You just need the right words