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In 1928, a Soviet scientist convinced that young blood could rejuvenate the body exchanged his own with that of a university student. The experiment turned the student into a survivor and the researcher into a of the first victims of the modern pursuit of longevity. The great Russian bet. If the question is whether aging can be delayed, Russia has decided to respond with an initiative of extraordinary dimensions. Under the direct impulse of Vladimir Putin, the weekend counted the wall street journal that the Kremlin has made longevity a national priority through a program valued at about $26 billion that seeks to develop technologies capable of prolonging human life and combating age-related deterioration. What for many Western leaders and businessmen remains a private bet financed by technological fortunes, in Russia has become a state strategy which combines genetic research, organ printing, xenotransplantation and other experimental technologies with the promise of saving hundreds of thousands of lives before the end of the decade. New organs for aging bodies. One of the most ambitious ideas of the project consists of progressively replace the defective parts of the human body as if it were a complex machine. It we have told before and Putin himself even commented publicly on the possibility of achieving a kind of practical immortality through the continuous replacement of damaged organs. To get closer to that goal, Russian scientists are working on two main lines: three-dimensional bioprinting of living tissues and the growth of human organs inside minipigs, a variety of pork considered especially compatible for this type of research. The stated goal is to achieve functional transplants of laboratory-produced organs by 2030, a goal that, if achieved, would represent one of the most important biomedical advances of the century. Genes, tissues and pigs at the service of longevity. The program also includes the development of gene therapies aimed at slowing down cellular aging. According to Russian authorities, these treatments represent some of the most promising tools to combat the biological wear and tear that accompanies the passing of the years. At the same time, researchers they claim having managed to print human cartilage and a mouse thyroid gland using bioprinting techniques, preliminary steps towards much more complex structures. The combination of Genetic engineering, organs grown in animals and the manufacture of artificial tissues paints a vision in which medicine stops limiting itself to repairing damage and begins to replace entire components of the organism. Putin’s daughter and the architects of the project. Behind this strategy appear some of the most influential figures of the presidential circle. Among them stands out Maria Vorontsova, Putin’s daughter and an endocrinologist linked to various state genetics programs, as well as the physicist Mikhail Kovalchuk, director of the historic Kurchatov Institute and one of the Kremlin’s main scientific ideologues. Kovalchuk holds that humanity is approaching an era in which organs can be routinely repaired or replaced, prolonging life for increasingly longer periods. For its defenders, aging will no longer be seen as an inevitable destiny and will begin to be treated as a technical problem susceptible to scientific intervention. Between cutting-edge science and community doubts. However, the program’s promises are far from to generate consensus. Many researchers they point out that much of the progress announced by Russia has barely been published in peer-reviewed international scientific journals. Some scientists who participated in the early stages of these investigations hold that there is a great distance between the proclaimed objectives and the results actually demonstrated. International sanctions, scientific isolation derived from the war in Ukraine and the difficulty of collaborating with Western centers also limit the capacity Russian to validate many of these projects. For critics, some of the statements made by the authorities should be interpreted more as aspirations for the future than as technologies close to becoming a reality. Personal obsession turned into state policy. Putin’s fascination with longevity it’s not new. For years he has cultivated a public image associated with physical strength through exhibitions Carefully constructed for sporting activity, hunting or outdoor adventures. At the same time, their behavior during the pandemic showed a extreme concern due to illness and physical deterioration, with strict quarantines, disinfection protocols and isolation measures that attracted the attention of the entire world. At 73 years old, also surrounded by an aging political and economic elite, the fight against the passage of time seems to have become more than a personal curiosity: it is part of a strategic vision shared by much of the Russian leadership environment. The long Russian tradition. The current project does not come out of nowhere either. Russia and previously the Soviet Union have historically shown a recurring fascination for research aimed at prolonging human life. Since the experiments with rejuvenating blood transfusions carried out by Alexander Bogdanov in the twenties until the theories of Oleksandr Bogomolets Regarding a life expectancy of 150 years supported by Stalin, different generations of Soviet and Russian leaders have pursued the idea of ​​overcoming aging. Paradoxically, many of those pioneers they died long before to reach the extraordinary ages they defended. A race against an uncomfortable demographic reality. The bet is even more striking because it takes place in a country that continues to suffer some of the worst mortality indicators of the developed world. Male life expectancy in Russia He is currently around 68 years, well below that of the United States or Western Europe. In this context, the gigantic longevity program promoted by Putin it reflects both a scientific ambition and a national need. The question is whether printed organs, genetic treatments and minipigs capable of hosting future transplants will bring Russia closer to that vision of a increasingly longer life or if they will end up joining the long list of projects that promised to defeat aging and ended up crashing into a biological reality much more difficult to defeat. Image | IToldYa, Press Service of the President of the Russian Federation, Picryl In Xataka | We knew that living … Read more