Mobile Tech & Gadgets

These are the best chollos that Mediamarkt has in your campaign “Make a renewal”

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Until May 12 at 9 am, Mediamarkt its campaign is in force “Get a renewal”, With which to get technological devices at the best price. With savings of up to 400 euros on television, 130 euros in telephony and 200 euros in computer science (among other discounts), these are some of the best chollos we have found in this campaign. Smart TV TCL 55p655 by 289 euros: 55 inches and with Google TV. Samsung Galaxy S25 by 849 euros: 6.2 inches and 256 GB. MacBook Air M4 by 1,059 euros: 13.6 inches and 256 GB. Xiaomi Redmi Watch 5 Active by 26.99 euros: With 2.07 inches screen and Xiaomi Hyper OS 2.0. Wireless headphones Samsung Galaxy Buds Fe by 54 euros: With noise and very comfortable cancellation. SMART TV TCL 55P655 If you are thinking about renew your old TV, this TCL 55p655 It is a good option to take into account during this Mediamarkt campaign. Its usual price is 399 euros but, now, you can get it reduced to 289 euros. This is a television with panel goes from 55 inches With 4K resolution. It is compatible with HDR10 and works under the operating system Google TV. Its speakers offer a power of 30 W and come with HDMI 2.1, WIFI and Bluetooth. * Some price may have changed from the last review Samsung Galaxy S25 For those who seek to change mobile and have thought of a high -end terminal, this Samsung Galaxy S25 is now reduced during this Mediamarkt campaign. You can take it by 849 euroswith 100 euros discount Regarding its usual PVP. He Samsung Galaxy S25 Mount a 6.2 -inch Dynamic Amoled panel with FHD+resolution. The terminal brain is the Qualcomm Snapdragon 8 Elite processor, accompanied by a 12 GB RAM and 256 GB of internal memory. Its main camera is 50 MP and works under the Android 15 Operating Systemwith ONEUI 7 customization layer. Samsung Galaxy S25 AI Smartphone 256 GB Grau * Some price may have changed from the last review MacBook Air M4 The Macbook Air is Apple’s most economical laptop and, now, you can also get it on Mediamarkt. Specifically, this macbook air m4 has applied a 100 euros discount And you can take it by 1,059 euros. This MacBook Air M4 It has a 13.6 -inch Liquid Retina screen and its brain is the powerful M4 chip. Comes with 256 GB of storage and is very light (it only weighs 1.24 kilos). Its battery offers up to 18 hours of autonomy and allows you to enjoy Apple Intelligence. Apple 2025 MacBook Air of 13 inches with m4 chip * Some price may have changed from the last review Xiaomi Redmi Watch 5 Active Another of the chollos we have found in this Mediamarkt campaign is this smart watch of the Xiaomi firm. It is on offer for 29.99 euros although, in addition, you have a Extra three euros discount in cart, which makes it available for 26.99 euros. This Xiaomi Redmi Watch 5 Active It has a 2.07 -inch AMOLED screen with resolution of 432 x 514 pixels. It works under the Xiaomi Hyperos 2.0 operating system and is compatible with both Android and iOS mobiles. Xiaomi Redmi Watch 5 Active * Some price may have changed from the last review Samsung Galaxy Buds Fe wireless headphones The last of the chollos we have found in Mediamarkt that is worth these Samsung Bluetooth headphones. The Galaxy Buds Fe have a usual price of 69 euros but, now, you take them with 15 euros discountsince they are available for 54 euros. These wireless headphones of the Korean firm come with Noise cancellationwhich is activated with only one touch and also incorporate the transparency mode. Your battery promises up to 30 hours of playback and have IPX5 certification and a compact and ergonomic design. * Some price may have changed from the last review Some of the links of this article are affiliated and can report a benefit to Xataka. In case of non -availability, offers may vary. Image | Webedia, Samsung, TCL, Xiaomi and Apple In Xataka | Best iPhone. Which to buy and recommended models based on budget, tastes and quality price In Xataka | The quietest ceiling fan: which one to buy? Tips and recommendations

The Chandra X-ray Observatory shows us how a neutron star has “fractured a bone” to our galaxy

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As if it were the radiography of a broken bone, the last image that has come to us from NASA shows us the image of a whitish structure whose natural silhouette has been “fractured” by the passage of a mysterious object. An object in whose nature we have been able to investigate thanks precisely to the recent observations. The fracture. The new image It was captured Combining captures of different astronomical observatories and shows us the fracture in G359.13142-0.20005 (abbreviated as G359.13) as well as the object that would have caused this fracture: a neutron star or pulsar. The “bone.” G359.13, the “bone” of this photo, is a cosmic structure called sometimes also as “snake.” This cosmic filament expands over about 230 light years and is about 26,000 light years from the earth, near the core of our galaxy. Filaments that emit radio waves that make them detectable from our planet. These structures are directed, NASA explainsby magnetic fields that run in parallel to them. The radio waves that come to us are caused by particles loaded with energy that form spirals along these magnetic fields. Joint work. The image has been possible Thanks to the combination of observations taken in different segments of the electromagnetic spectrum. As we pointed out, the “bone” of the photo is a visible structure in radio lengths, and its observation has been possible thanks to the Radiolescopes of the Merkat Observatory. When “diagnosing” the cause of this fracture, however, resort to X -rays. Those of Chandra Space Observatoryto be more exact. The reason is that the main suspect of causing this fracture is hidden in the structure itself. Fortunately, this mysterious object also emits in the frequency of X -rays, since what is hidden after this “fracture” seems to be a neutron star or, probably, a pulsar. According to NASA, this object would be emitting light both in the form of radio waves and X -ray, to which an additional x -ray source caused by electrons and positrons (its antiparticles) accelerated to large energies should be added. To millions of km/h. The fracture itself would have been caused by the irruption of the pulsar at exorbitant speeds. According to astronomer estimation, this speed would be between 1.6 million and 3.2 million kilometers per hour. A study linked to this image was published last year In an article In the magazine Monthly Notices of the Royal Astronomical Society, Change perspective. The image is a memory that sometimes things are not what they seem. The light that our eyes perceive is a tiny fraction of the emissions that exist in the cosmos. Sometimes the invisible to our eyes can be made visible using the correct instruments, while other times the opaque may not be so much if we change perspective. In Xataka | One of the objectives of the Webb Space Telescope was to look for signs of life on other planets. He just found them Image | NASA/CXC/Northwestern Univ./f. Yusef-Zadeh et al; RF/Sarao/Meerkat; NASA/CXC/SAO/N. Wolk

The fear of renewables

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The current energy model is again on the table after the blackout of April 28 in Spain. After a few weeks where the Spanish nation was covering 100% of your demand with renewable and exporting the remaining energyon the other side of the Pyrenees, France was observing with concern how their nuclear They have had to run into idle. And not because of a technical problem, but for an increasingly uncomfortable reality: the southern renewable boom is challenging northern nuclear hegemony. France resisting. While much of Europe has taken an address towards a system focused on clean energy, France redouble your commitment to nuclear energy With a production 70%. However, this scenario is not a technical preference, but a strategic ambition since the Gallic country seeks to be the battery of Europe. A centralized, controlled and export model. However, the renewable advance of countries such as Spain complicates that plan. In contrast. Spain, With a commitment determined by renewablesNot only has it reduced its dependence, but it begins to question the profitability of the French nuclear model. In April, he covered more than 60% of his demand with clean energy and exported a significant part to Francejust at the moment when several Gauling reactors were standing. As has explained for the avant -garde Eloy Sanz, professor at the University of King Juan Carlos I: “The debate is not just technical, it is deeply geopolitical.” And he added: “France wants to maintain its energy leadership position in Europe, but photovoltaic and wind are gaining ground and do so with increasingly low costs.” A silent competition. This conflict is not always perceived at first glance, but it is deep. In Brussels, the fight revolves around which technologies should receive public aid. Paris pressed for nuclear Be considered “green” and can opt for European funds, while countries like Spain are promoting a transition based on renewables, storage and intelligent demand management. The problems are at home. The France Academy of Sciences itself has criticized The new government energy plan (PPE3), describing it as “unrealistic” and “disconnected of reality. ”In addition, the controversy is not less: The French Nuclear Investment Planwhich includes up to 300,000 million euros To prolong and build new reactors, it has caused an internal political crisis, According to Le Point. France’s resistance is not born from fortress, but from the urgency of defending an increasingly discussed position. Maintain the position. France resists, yes. But it does not do it from the strength, but from the need to protect an increasingly questioned position. The renewable revolution in southern Europe is not just a promise of the future: it is already a reality that Tension pricesnetworks and policies. Energy leadership in Europe is in dispute, and this time, Spain arrives with a viable, exportable and increasingly difficult proposal to ignore. Image | François Goglins Xataka | The production of renewables in Europe is so strong that it is forcing nuclear power plants to work

We do not know if the AI ​​is going to eat your work, but the CEO of some startups are determined to convince you of it

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AI comes for your work. It is the message that does not stop arriving since Chatgpt reached the market. And even before. The impact of artificial intelligence on the world of employment It can be hugebut for the moment They have not been noticed Its effects too much. That, they say more and more frequently the CEOs of technological companies, it will change. First, Shopify. Less than a month ago the CEO of Shopify, Tobi Lütke, He sent a memorandum To its employees with a clear directive: “Using AI effectively is now a fundamental expectation for everyone in Shopify.” In fact, he indicated that before expanding a workforce or investing in other tools, project managers should have exhausted all the ways to do that task with AI already available tools. Then Fiverr. The last to adopt a decision and speech of this type is Micha Kaufman, CEO of Fiverr, who in a memo to his employees emphasized the importance of protecting their careers in the face of the growing influence of AI. His message was overwhelming: “This is the unpleasant truth: AI comes for your work. Demons, it also comes for mine. This is a call of attention. It does not matter if you are a programmer, designer, product manager, data scientist, lawyer, customer service representative, seller or financial: the AI ​​comes for you. You must understand that what were previously considered” easy tasks “will no longer exist; what were considered” difficult tasks “will be” difficult tasks ” Easy, and what was considered “impossible tasks” will be the difficult thing. Finally (for the moment), Duolingo. Luis von Ahn, CEO of Duolingo, announced its template A few days ago his intention to be “an Ai-first. Among the measures that the company will take is to “gradually stop hiring freelancers to do the work of which AI can be commissioned.” Of course, Von Ahn apostilled, “Duolingo will continue to be a company that deeply cares about its employees. This does not replace the DUOS (company employees) with AI. It is about eliminating bottlenecks so we can do more with the spectacular duos we have now.” Many said it before, many will say it later. The message is explicit, but of course it is not new. The appearance of Chatgpt caused this type of predictions to become increasingly frequent, and little by little we have seen how the CEOs of large companies have talked about the impact that AI will cause on work. Above all, in the world of programming: Jensen Huang, CEO of Nvidia, was clear a year ago than No one should learn to programand they have also said Mark Garman (CEO of AWS) or Satya Nadella, CEO of Microsoft. Mark Zuckerberg joined that prediction a few days ago and assured that in 12-18 months the majority of the code would be written by an AI. And I didn’t talk about the machines autocomplete code, but that they would write it completely. First it will help us, then (perhaps) it will replace us. Many experts believe that AI It will enhance our productivity And it will help us do more And better work than ever. It is what happened with the computer or internet, but with AI there is a clear fear that I end up going beyond and completely doing our work. The possibility is there, although with other technological revolutions, there will be more threatened jobs and others that will be less. Bill Gates, for example, believes that Doctors and human teachers do not have much future And Sam Altman, CEO of OpenAI, states that the impact of AI on employment “It is a huge, huge problem“. Perhaps 140 years of history point to a surprising future profession. Hairdressers. Between 1871 and 2011 Technology created more jobs than destroyed. The 2015 study published In The Guardian It focused specifically on data from the Census of England and Wales, and that allowed to assess the impact of technology on the world of employment. The most physical works clearly fell into a fee, but while or other professions were created, or professionals were added to which there were already. For example, surprise: the number of hairdressers grew prodigiously throughout those 140 years: just 0.1% of the workforce in 1871, this group went on to represent 0.6% in 2011. But the impact is inevitable. There are more studies and forecasts that occurred before the current “revolution” of AI. In 2018 the World Economic Forum (WEF) He published his report ‘Future of Jobs 2018’. In their conclusions they pointed out that automation would eliminate 75 million jobs by 2025, but would create 133 million new functions. The balance has changed five years later. In your 2023 reportthis agency pointed out that in the next five years it is estimated that 83 million works will be lost and 69 million will be created. The funny thing is that lately workers They seem to be somewhat more optimistic With his future. Image | Fiat Chrysler Automobiles In Xataka | Thousands of employees use AI in their work. More and more do not want their bosses to discover it

In favor and against an increasingly international and ‘desestationalized’ diet

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Yesterday There were creeks in the supermarket. Round, orange and bittersweet, the fruits of the loquat of Japan are one of those little miracles that gives us May. And I know it is an anecdote: a handful of thousands of tons of an absurdly seasonal product distributed by the supermarkets of five or six Spanish provinces. But it made me smile, first; And frown, later. Because yesterday, looking at those two bars in the middle of the ocean of fruits and vegetables, I realize that we almost always eat the same. Yes, a varied and balanced diet: provided we do not get out of the same 20 or 30 fruit and vegetable references. There is a battle in the world of distribution forever, let’s eat the same; so that our diet is the most standardized the same; so that there are no media in the supermarket. It may seem exaggerated, but there are examples to thousands. If we think about it, the idea of ​​being able to go down to the store and find avocados whatever the time of the year is almost magical. Avocado flowering in Spain It occurs in April. Also in March and May, but especially in April. The collection and marketing, on the other hand, goes from October to March. What happens in the spring and summer months? Where do the avocados that fill the shelves of the supermarkets come from? The answer is that of Peru. Of other sites, but fundamentally from Peru. The market and globalization has achieved something incredibly difficult: to be able to have seasonal products throughout the year. Sometimes, bringing them from other areas of the world (as in the case of avocado); Other times, looking for macrovarities that allow their cultivation throughout the year. That is what happens with potatoes (extra -time, early, half -season and late) and tomatoes. The Jungle Law. In this sense, international trade and international coordination select products with the ability to generate sufficient demand to ensure its supply during the year is profitable. As not all products allow it, nor all consumer groups are large enough: the current result is that many traditional products can only be found at the local level and those of great consumption The shelves of the supermarkets fill half the world. In our pantry there is a fierce knife fight from which only the most suitable products for these plethoric market societies come out. Is such a standardized diet ‘a good idea? Without a doubt, it has positive things. For the love of God, we can eat avocados at any month of the yearHow are you not going to have positive things? For thousands of years humanity has had to eat what it touched, but now we are very close to simply eat what we feel like. And that, even in a subject so crossed by cultural, social and personal factors Like food, it limits the future of gastronomy: it unifies it little by little, it makes it less diverse and more insecure. But, without a doubt, more appealing: a breakfast buffet in a hotel of many stars: the best – the most popular – of each kitchen in the world. While science fiction writers imagined a future with astronaut food, A kind of Soylent with steroids. What we are discovering is that the diet is changing, yes; But towards the promise that in the end We will all eat more or less the same. Image | NRD In Xataka | How, when and why the tomatoes will know Tomato again?

In his second trailer, ‘Gta VI’ aims to exploit one of the great ideas so far absent in the franchise: love

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Although it sounds strange at this point, the Second trailer of ‘GTA VI‘points to something unexpected: Rockstar has matured. Or at least, he intends to continue with his purpose of making games more adults than those who gave him fame, an intention that started with ‘Red Dead Redemption 2‘. For the first time in the franchise, we see unthinkable maturity notes a few years ago. Hello to love. The plot core of ‘GTA VI’ will undoubtedly be the love story between Lucia and Jason, something unusual in a franchise full of promiscuity, prostitution, unsatisfactory marriages and lonely antiheroes and without time for love. This is what Rockstar tells us in the official synopsis: “Jason and Lucia always knew that the letters were against them, but when a blow that seemed easy to go wrong, they are trapped on the darkest side of the most sunny place in America, in the midst of a criminal conspiracy that extends throughout the state of Leonida, and forced to depend more than ever of each other if they want to go out alive.” Goodbye to the cartoon. If something puts on the table the new trailer of ‘GTA VI’ is A graphic realism never seen in the serieseven though we could be talking only about kinematics. And that realism has to bring hand in hand A change in the arguments that develop. Let us remember what the characters of ‘GTA III’, ‘Vice City’ or ‘Liberty City’ were: excessive, big heads, of schematic movements, almost cartoons. That has ended, and emotionally, the characters have to live up to it, in the same way, as we pointed out in their day, The demands of female representation have changed. A clear inspiration. Before we know more details about the argument (there are already rumors that Jason It could be an undercover policeman), the clearest reference of GTA VI are Bonnie Parker and Clyde Barrowthe couple of robbers of banks who lived a bloody romance in the Chicago of the thirties. In this trailer we see Jason and wore a bank together, the first picking up the second when it comes out of jail, and sharing some beers, a sunset and some passionate scenes that perspire a certain unusual tenderness in the ‘GTA’ games. But a shadow looms on them. The thing may not end well: Rockstar games, especially the recent ones, usually deal with betrayal, one way or another. In ‘GTA v‘, where we were driving alternately to the three protagonists, in the end we were asked to choose between betraying our classmates or accepting a last mission with them. In ‘Red Dead Redemption’, betrayal when the protagonist seemed to have reached peace was inevitable. And in this ‘GTA VI’, if we alternately control the protagonists in the ‘GTA V’ style, the player could have to resort to a similar decision: loyalty to his partner or fulfill a mission. The model is ‘Red Dead Redemption 2’. It is the most sophisticated and deep game at the level of characters that has set rockstar to date. He left behind the grotesque composition of the protagonists of ‘GTA V’ and opted for emotion: in ‘RDR2’ we see Arthur Morgan learn with the player valuable lessons about betrayal, responsibility and – while he faces his own death, and as it is inevitable taking into account the title of the game – redemption. If Rockstar looks for a reference for maturity and adult characters, his own masterpiece is his model. A logical trajectory. From ‘Red Dead Redemption’, published fifteen years ago, the detour to more mature and adult arguments is indisputable. He was followed by the police key ‘La Noire’, the turn of ‘Max Payne’ in its third part towards personal hells and the second installment of ‘Red Dead Redemption’. Only ‘GTA V’ and, obviously, the verbenero ‘GTA online‘, to which you have to feed apart, they have left that line. But even recognizing that the fifth installment of the franchise is a look at more frivolous and caricaturescos times, posed unprecedented issues and approaches in the criminal saga. For now, noise and fury. For now, all this are conjectures, such as The brilliant idea that all we are seeing is the start of the game and Jason dies in the early hours of history. We cannot deduce from the second trailer what are going to be the key points of the argument, but the official information makes it clear that the relationship between Lucía and Jason (include or not deaths, betrayal or something else) will be openly romantic. And what is clear from the tone and visual style of the trailer is the potential of the game of giving an unprecedented impulse to the depth of the stories that are told in video games. And Rockstar is not known for letting this type of opportunities pass. Header | Rockstar In Xataka | The delay of ‘GTA VI’ goes far beyond a mere change in the calendar. It is an earthquake for industry

Opinions, first contact and photos

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More practical and more comfortable. Those are the main identity of the new electric renault 4, an alternative to the Renault 5 that clearly has a more youthful approach, more than a driver than this SUV version that is not so linked to its past but that is equally careful. The electric Renault 4 is one of those cars that one arrives with the promise of another car. It is very likely that the client will land at the concessionaire attracted by the electric Renault 5 and when he sees the rear seats and the trunk is decided by this option that is Much more practical For a family with children. It is easier to accommodate these in the rear seats. In fact, adults will travel more easily. And, above all, it has a trunk and a much wider load space. This is our first contact with this reinvention of Renault 4. Electric Renault 4 Technical Card Renault 4 Body type. B-SUV of five seats Measures and weight. 4.14 meters long, 1.77 meters wide, 1.50 meters high and 2.54 meters of wheelbase. From 1,410 kg of weight (no more details are specified) TRUNK. 420 liters Maximum power. 110 kW (150 hp) WLTP consumption. 14.7 kWh/100 km for 40 kWh battery version. 15.1 kWh/100 km for the 5 kWh battery version. Environmental Distinctive. Zero emissions Driving aids (ADAS). Confirmed the minimum required by the European Union. Front and rear emergency braking. Centering lane with adaptive cruise control. OTHERS. Open R link built on Android Automotive, compatible with Android Auto and Apple Carplay. Electric hybrid. No. Plug -in hybrid. No. electric Yes. 90 kW versions (122 hp) with 40 kWh battery and 110 kW (150 hp) with 52 kWh battery. price and launch Already available: 40 kWh battery: from 28,752 euros 52 kWh battery: from 31,632 euros A car that is bought with the head It should seem obvious when one is going to leave “thirty -many thousand euros” in a product. We try to look for rationality in objects such as a computer, hiring the fiber of the mobile, when choosing the supermarket we bought. But buying a car is still A point of irrationalityto buy with the heart. To assume that we aspire to have that car for at least a decade ahead. And that’s why aesthetics remains key. That is why brands continue to invest in aspirational products because they know they attract new customers. And that if these new customers do not buy that car will be made with another that is cheaper or more practical but they will already be in their networks. A formula that is only possible if certain identity signs are maintained. With the Renault 5 and 4 that happens. I have rarely felt as observed as in Our first contact of Renault 5. Beauty is that purely subjective element that, curiously, makes majority public to the same product. Some goal will have. Renault has managed to attract looks with his Renault 5. A beautiful car, careful, well topped but whose rear seats and their trunk can leave out many families. For them, the French have that electric Renault 4. A little wider inside, more space in the rear seats and a qualitative leap in the trunk that grows to 420 kilometers. It is not so striking like him Fivedoes not have that captivating but Renualt air has managed to remember the classic 4 cans with an aesthetic that trusts most of its links with the past to a front grill with two round headlights and two rear optical groups that modernize the original. To this is added that, as we say, Renault has made him care. The configuration is the same as in the Renault 5, 10 -inch screen for the central and 7 or 10.1 inches (depending on version) for the instrument frame, both supported in the same frame that takes advantage of Android Automotive to display a set of brilliant graphics and results that are especially striking for the can of the panels. The rest of the cabin shines where his brother model did. The splash furniture presents an illuminated infographic with the name of the model, has well -chosen padded and the seats are comfortable. The steering wheel feels of good quality. And all this is presented with an attractive and brave color palette that breaks with the anodinos (and almost standard in the market) white, black and the wide gray range in all its tones and saturated. If we talk about your system of Infoentrateas we said, there is no complaint. The menus are simple to control and everything is there where you expect. A strip of four direct accesses on the left side and direct access to multimedia systems and a second function in the right. Panel, the latter, which can be hidden. In the center we have the Google Maps map with real -time traffic information. Everything unfolds quickly and without suffering any LAG. It is appreciated that under the central panel the well -known physical controls of air conditioning are maintained. The information in the instrument frame is well distributed, with a configurable central panel to the driver’s taste (including the map) and a right side in which the information related to consumption is shown. Compatibility with Apple Carplay and its wide versatility, carrying Apple’s map to the instrument picture if you want. The button that deactivates adas aids to the driver with a simple touch (activates a personalized configuration) and physical controls in the steering wheel, well distributed and easy to handle is also maintained. What still seems uncomfortable is the arrangement of the controls of the right where the transmission lever, the watering wiper, multimedia control and, now, the cams are crowded. Because the electric renault 4 adds some cams that allow controlling the regenerative braking to the point of adding the One pedalthe function with which we can control the car only with the accelerator. Regeneration when lifting foot is strong enough … Read more

We had been trying to know what neurostrogens served why they served. We have just discovered a clue: they regulate the appetite

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In recent years we have seen progress in the study of the hormones responsible for regulating our appetite and the feeling of satiety, hormones such as those that transmit from the stomach to the brain the information that we have already consumed our ration of food and we can stop. However, now we just found one of these hormones in an unexpected place, in hormones that until now we associated mainly with reproduction. From the stomach to the brain. A Japanese researchers team He has found A relationship between neurostrogens and appetite regulation. Neurostrogen. The Estrogens They are hormones that we usually associate mainly with female reproduction. In this context, aspects such as the development and maintenance of female sexual characteristics regulate. But this “family” of hormones has a diversity of members that cover other contexts. For example we can find the phytostrogen produced by plants or neurostrogens. The latter are produced by the brain, as their name suggests and until now they represented a mystery in our biochemistry since we do not know which or what their exact functions are. Looking for an answer. The team I investigated precisely The role of these brain hormones. For this they turned to mice in a laboratory. They compared several groups of mice, including some without the capacity to produce estrogen; and others to whom the production of neurostrogens had been inhibited. The latter was eliminated by aromatase, an enzyme used by the brain to synthesize these hormones. They thus verified that the group of mice that lacked ovaries and those without aromatase showed a greater body mass and greater food consumption compared to the mice of the control group. The team Then he reactivated The gene linked to aromatase, returning the enzyme to its brains. They saw that the mice went on to consume less food. MC4R. The team found that these mice to whom the ability to synthesize aromatase had been returned and with it neurostrogens showed a “marked increase” in the expression of the melanonortine 4 (MC4R) receptor, a receptor known for its role in the regulation of food consumption. This led the team to conclude that the neurostrogens produced through aromatase were involved in the expression of the receiver and that it was through it that were able to “suppress” the feeling of hunger. The role of leptin. The study, explains the responsible team, also indicated that neurostrogens could also increase the ability of the brain to leptin, one of the hormones whose function we already knew related to the regulation of appetite. “We observe that mice with restored neurostrogens responded more effectively to leptin treatment,” explained in a press release Takanori Hayashi, co -author of the study. “This may be due to the fact that neurostrogen increases the natural response of the body to the mechanisms that suppress appetite.” The details of the study were published In an article In the magazine The Febs Journal. The eye put into treatments. The team responsible for the study Mention the possibility that this discovery opens new therapeutic paths focused on development detracts for weight loss. They also point out that understanding the physiological function of neurostrogen could also help us find ways to regulate estrogen more precisely in our bodies, for example in contexts such as menopause or postpartum. In Xataka | We already know where the microplastics get the lettuce that you eat in the salad: from the air Image | Milad Fakurian / Sander Dalhuisen

how difficult it is to protect copper in a 15,000 km network

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“You cannot monitor 24 hours 15,000 kilometers of network, but you will have to put more means.” The phrase left her yesterday during An interview In Antena3 the president of Renfe, Álvaro Fernández de Heredia, and is interesting for several reasons. First for what he says. Second, for how he says it. And third (and fundamental), when he says. The rail operator complaint comes after the bird line between Madrid and Sevilla lived chaotic hours on Sunday by the Cable theft of copper in several points of the layout. What happened is serious, but it reveals something more worrying: how difficult it is to shield a network thousands of kilometers. Collapse on the Madrid-Seville line. The bird line between Madrid and Seville (The dean of the Spanish high -speed network) did not go through its best moment on Sunday night and Monday morning. Delays Stakes arrested for hours. Collapsed stations. AND More than 16,000 passengers affected. Although the collapse coincided with An incident starring an Iryo train, both Adif as the Minister of Transportation, Óscar Puentethey did not take long to relate what happened to the theft of cable on the line. “A serious sabotage act”. Sunday night, with the bird line between Madrid and Seville still knocked out, Oscar Puente spoke already of a “serious sabotage act” and pointed specifically to the theft of cable at various points distributed within about 10 kilometers. The thefts were recorded in five different locations distributed among the PK 102+200 and 92+800in the province of Toledo. In total the thieves took 150 m of copper cable. Click on the image to go to Tweet. A booty of 300 euros. The big question that was bouncing on Sunday and has continued to do so yesterday and today is what is the reason behind what bridge closets “sabotage.” Copper It has been revalued coinciding With the tariff war unleashed by Trump, but a priori the metal stolen in the Toledo line is rather scarce. The Government delegation has made accounts and calculates that its value Barely reaches 300 eurosso it has suggested that the real objective was to “block the road.” “That cable, which has very little value, is optimal for primar service to the line,” ditch. Bridge insists on talking about “A coordinated action” perpetrated by someone who “knew what was going” while the issue of the political debate. The PP has even related to the “obvious deterioration” of public services and He has demanded an “audit of the entire network”. Beyond the political or research sand that It has already opened A court of Toledo, what happened in the bird line between Madrid and Seville raises a fundamental question: Is it so easy to steal on the network? It is not the first time that the rail network suffers a robbery or sabotage. In 2022 The Civil Guard stopped to a band that was dedicated to stealing copper in the bird line in Valladolid, Palencia and Burgos. In total it had been made with a boot of 185,000 euros. And years before, In 2015he had already arrested 28 people from a Madrid organization related to the theft of more than 30,000 m of rail cable in several communities. In that case it was estimated that their “blows” had cost about 840,000 euros. The Rodalies case. The above are only two examples that can be easily found in the newspaper library. There are moredistributed by different latitudes of the Spanish geography, and that not only affect the high speed network. Does Just a year Without going any further Catalonia suffered the theft of 40 meters of cable on the Rodalies network at 300 m from the Montcada-Bifurcació station. The incident in turn caused an over -teaching that ended up affecting the service. Yesterday Europa Press It echoed From a balance of the security forces that show that only in 2024 they registered 4,433 copper wiring and conductive materials, 87% more than a five years. In total, 987 people were arrested and investigated, double that in 2019. The balance is general and does not only relate the robberies that affect the rail network, but still gives an approximate idea of ​​how frequent these types of crimes and also how it has been able to affect them the price increase of copper. A great network, a great challenge. The key was given yesterday by Fernández de Heredia during Your interview In Antena3: Spain has a wide (very wide) railway network and that is at the same time a chance and a huge security challenge. The Adif and Adif Av enclos 15,519 kilometers of network, of which 9,984 are electrified and just over 3,700 high -speed connections of different types. And that is just the Railway Network owned by ADIF. To control them in 2021 the organism He tendered a contract of surveillance and security services for three years (from April 2022 to March 2025) that amounted to 210.8 million euros. But still the challenge of monitoring the entire network is considerable. The bridge itself He explained That the 150 meters of stolen cable over the weekend were taken out of difficult access areas, between forest and olive groves. “We will have to put more means”. “You cannot monitor 24 hours 15,000 kilometers of network, but more means will have to be put to avoid it because the disorder caused by these robberies to travelers is very high,” He insisted yesterday The president of Renfe. In the past and before terrorist threats the government came to use the army to monitor the lines, as happened In July 2005after the attacks suffered in London. Images | Nelso Silva (Flickr) and TRANSPORT MINISTRY (X) In Xataka | The US has been dreaming of its first high -speed train decades: the California project is being a real nightmare

The second trailer of ‘GTA VI’ looks crazy, and is a sample of how good it feels to go against the industry

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The wait until May 26, 2026 will be made long. In a strange ad, Rockstar confirmed a few days ago that the release date of ‘GTA VI‘It was delayed from an indefinite moment of this 2025 At the end of May next year. It is something that It has several readingsbut one of them was that they would soon launch a new trailer that, finally, would set the final launch date and, announcing the delay in advance, would cushion the blow. This has been. The company has just launched the Second Trailer of ‘Grand Theft Aut VI’ And … he is overwhelming. If the first launched in 2013 already allowed us to theorize whether it was something moving in real time or was a pre-control scene, this second trailer points to tour the same path. And the reason is that there are scenes of ‘GTA VI’ that are a real madness. ‘GTA VI’ will squeeze a decaffeinated generation First of all, I have to clarify that we can only judge the visual quality of the game with the means that we have available so far. To perform deeper analysis, we will have to waitat least, at the moment we have GamePlay scenes itself, but I think we can start making illusions with what Rockstar is cooking. For three reasons, in addition. The first is that, as I said, the first game of the game has already allowed experts to discuss its nature. Digital Foundry is a British media specialized in the visual and technical analysis of video games and They debated Long and lay on whether the trailer was in real time (that is, the engine of the game and scenes extracted from it) or a scene rendered beforehand. Some visual errors as Jaggies -S. Sierra- allowed the pixel counting, and the washed image of the edges points to the use of some type of tool such as FSR or DLSS. The second reason is that Rockstar is not Ubisoft and it is not a company that has accustomed us to CGI videos before the launch of the game itself or to Visual Downgrades. The third reason to believe that the game will end up seeing as in these trailers is that we have ‘Red Dead Redemption 2‘As an example. The 2018 title, without having received a patch for the current generation, continues to be better than many games of this generation, and that was designed to function in 2013 consoles. Come on, what There are hopes in ‘GTA VI’ at the visual level. And, as we say, we have reasons (and not only for these precedents). Trailer screenshot The new video begins very, very high, with some characters modeling that seem spectacular, very realistic animations both bodily and facial, without falling into the exaggeration of features, and all this bathed for what, I think, is the element that makes the trailer look as well as it looks. Because the textured seems very good to me, but the lighting that bathes each scene is to not believe it. Among all the moments, the one who has left me speechless is one at the beginning, when we see Jason returning in his car, at night, and observes a police detention. Trailer screenshot The flashes, The position of light spotlights And elements such as that good textured, the most realistic color palette than in the previous installment of the saga and gestures make me create that scene completely. But it is not the only one: Trailer screenshot Trailer screenshot Trailer screenshot I am somewhat tired of the term “photorealism” we have been abusing from the launch of the first ‘Modern Warfare’, but it really is the only term that occurs to me to describe what I am seeing. Then there are the characters, with a certain caricaturized and stereotyped touch, but the physicists of elements and hairstyles, Reflexes on surfaces (The interior of the car is amazing) or the vegetation play to make the scenes … surprising. Perfect? No, of course, and we see distant elements such as the sand or water that have visual artifacts, as well as some textures such as Lucia’s hair at some time that seem flat, but the general level is so, so high that, for the first time from ‘Alan Wake 2‘ and ‘Warhammer Space Marine II‘, I feel that this generation of consoles is worth something. And with more merit if possible in the Rockstar title, since it is an open world, with the complexity that this implies. Rockstar promotional image Rockstar promotional image Rockstar promotional image It may be making many illusions, but it comforts me that people in Rockstar think that the game is going to see like this. Not current workers, something impossible in one of the most hermetic studies in the environment, but veterans of the company. One is Ryan Fuechliffe, member of Rockstar from 2009 to 2021 and who commented that ‘GTA VI’ will offer a “revolutionary” realism. Mike York, who worked as an animator in the company, also commented That the game will probably go to 30 frames per second because Rockstar was focusing on visual quality. But, although I seemed to me … wild, you have to have your feet on the floor. Obbe Vermeij, former technical director of ‘GTA 3’ to ‘GTA IV’ He pointed out That, although the first trailer was “incredible”, the technical jump may not be as large as the one seen in ‘GTA V’ and that could disappoint some players. As I have already said, you have to wait to see Gameplay because, obviously, these two videos that Rockstar has revealed play a lot with the rules of the visual language of cinema. Chamber tremors, paneos and angles that are typical of the kinematics of well -positioned virtual games and cameras and we will have to wait to watch the first video with gameplay. However, I return to my argument of ‘Red Dead Redemption 2’: Seven years later, the adventure of the … Read more

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