Most people take creatine for the gym. It is actually really useful against insomnia.

for a long time Creatine has been seen as a supplement intended for people who go to the gym to have a good muscle. However, this is changing completely to recommend that anyone take creatine for the many benefits of taking creatine to improve cognitive functions for example. Now, it is also being seen that it has a great component for the quality of life in people who suffer insomnia.

Sleep deprivation. The human brain represents only 2% of body weight, but consumes 20% of our body’s total energy. The main cfuel it has is ATPthe currency we use, and its ability to quickly resynthesize it determines our mental agility. But when there is sleep deprivation, energy levels drop and with it attention, memory and mood.

This is where creatine comes in, as a large study published in Nature in the year 2024which changed what we knew about acute creatine supplementation in anyone. In this case, the researchers demonstrated that a single high dose of creatine is capable of reversing the cognitive deficit caused by little sleep.

The results. Specifically, after 21 hours of wakefulness, the subjects showed a significant improvement in processing speed and working memory from taking creatine.

Furthermore, one of the effects of stopping sleep is brain acidification. In this case, creatine acts as a buffer, preventing drops in pH and positively altering the relationship between key metabolites such as phosphocreatine and inorganic phosphate. A discovery that complements the classic 2006 study which already indicated that doses of 20 grams a day for a week mitigated the deterioration in prefrontal cortex tasks and improved mood and balance after 24 hours without sleep.

Neuroprotection. As we age, the efficiency of cellular energy production decreases, which is why science is focusing on creatine as an agent. anti aging powerful. Something that is especially focused on women who are in perimenopause and postmenopause, where the protective effect of estrogens has been lost.

Of course, there is an important change in the dosage, since while the standard dose is 3-5 g, women over 40 may need between 8 and 10 g/day to see notable improvements in cognitive function and mitigation of hormonal “brain fog.” Furthermore, in women, in addition to improving cognition, there is also an improvement in the quality of muscle mass, which is a critical factor for longevity.

Older adults. A systematic review of 2025 and ESCEO studies directly associate creatine consumption with better cognitive health in adults over 60 years of age. In this case, creatine appears to compensate for the natural reduction of phosphocreatine stores in the aging brain, improving sustained attention and reducing mental fatigue.

The new paradigm. In this way, science is advancing to see that creatine is not just a matter of gaining muscle, since the brain is also a great consumer of this energy. The reality we have on the table is that creatine is one of the compounds most tested in humans, with an excellent safety profile even at high doses.

But in addition to all this, it is also the property that working memory has, since it is undoubtedly the most tangible benefit that we can have in the case of doing complex tasks that require great mental effort under very adverse conditions.

Images | HowToGym Sander Sammy

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