Having a coffee for many is something that It is essential to start the day. It is something that in our country has become a cultural habit, but it is also a very relevant pharmacological event. Since although many people’s day doesn’t start until this coffee, our body already has its own “start-up” system built in as standard that we could be affecting.
A good debate. Recently has arisen an idea that has set a precedent: Ingesting caffeine immediately after waking up interferes with the body’s natural biology. Specifically, with cortisolwhich is the stress hormone that allows us to wake up in the morning and sustain us throughout the day. Given this, It is recommended to wait between 60 and 90 minutes to drink your first cup of coffee.. Although… How much truth does this have?
If we analyze the most recent clinical literature and population studies, we discover that Coffee in the morning is, in fact, a powerful ally for cardiovascular healthbut its maximum effectiveness depends on fine synchronization with our hormones.
Natural injection of energy. To understand the effect of coffee on our body, we must first understand what happens when you don’t drink it. When you open your eyes, your brain doesn’t turn on like a switch, but instead starts a chemical cascade known as Cortisol Awakening Response (CAR).
This is essential, since upon waking up, cortisol begins to increase and reaches its maximum peak approximately 30 to 60 minutes after opening the eyes. A hormone that is essential to activate us, and that is released in large quantities, for example when we are stressed or there is danger.
A limbo of signals. In this way, if we introduce caffeine right into the body when cortisol is rising, we may be generating unnecessary overstimulation, increasing nervousness or so-called jitters.
Furthermore, caffeine (despite the fact that it hurts for some) does not provide real energy to our body, but what it does is block the adenosine receptors, which is responsible for making us feel tired. In this way, when we wake up, there is still some of this signal in the body and if we block it suddenly and too soon, when the effect of the coffee wears off, this accumulated adenosine suddenly binds to its receptors and causes the famous mid-afternoon fatigue.
What science knows. To date, there are no controlled clinical trials that compare the long-term cognitive performance of a group of people who drink coffee immediately versus another who waits 90 minutes. But what we do know is that there is a tolerance effect.
A study published in PMC points out that in regular coffee consumers, the cortisol response to caffeine is significantly attenuated. That is, your body has already gotten used to that morning “hit” and the hormonal interference is much less than in an occasional consumer. In this way, when we remove the morning coffee, it may be much more difficult for a person to properly start their body as they lack that ‘drive’ to which their body has become accustomed.
The night battle. Where the science is clear is in the use of caffeine late in the day. A study in Science Translational Medicine showed that a double espresso three hours before bed delays the circadian clock by about 40 minutes, seriously affecting sleep quality.
Is it worth waiting? If you are one of those who feel intense anxiety after the first coffee or if you experience an unbearable drop in energy at two in the afternoon, the recommendation to wait 90 minutes has physiological plausibility and can be a valuable personal experiment. By delaying caffeine, you allow cortisol to do its job and residual adenosine to be cleared more naturally so you don’t have that unpleasant mid-afternoon tiredness.
However, for the healthy general population accustomed to coffeethere is no evidence that taking it as soon as you wake up is harmful. We are only left with that effect of dependence on coffee that interferes with the internal ‘caffeine’ of awakening that our body produces. This is why the 90-minute rule is more advice based on clinical observation and biological logic than on robust studies.
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