We have found a plant capable of producing 40 cannabinoids. A closer plant evolutionarily to lettuce that to hemp

Cannabinoid compounds are closely related to gender plants Cannabishemp. A relationship that is manifested in the same name of these compounds, among which perhaps the most recognizable are THC (Delta-9-Tetrahydrocannabinol) and the CBD (Cannabidiol). However, this link is not exclusive. The Lanudo umbrella. The Lanudo Umbed (Helichrysum Umbraculigerum) is a plant originally from South Africa that stands out for containing 40 compounds of the cannabinoid familymany of them disconodful so far. This plant belongs to the genre known as paper or helicriso flower, a genus very raised from cannabis, and closer to plants such as sunflowers or lettuce. Beyond the striking of this fact (as contrast, in the plants of the genre Cannabis More than 100 cannabinoid compounds can be found), the team responsible for the analysis indicates that the finding can help us in the development of new therapies linked to these compounds. “We have found an important new source of cannabinoids and developed tools for sustained production, which can help explore its enormous therapeutic potential,” pointed in a press release Shirley (Paula) Berman, member of the team responsible for the finding. Diverse therapies. Although in some contexts we do not have solid evidence of its effectiveness, the therapeutic use of Cannabinoids It has been extending as long as the study of its biochemical and therapeutic properties progresses. A context in which these compounds do highlight is that of the relief of nausea in people in aggressive treatments such as chemotherapy. Other potential uses are in the treatment of pain, anxiety and epilepsy. As explained by the team responsible for the new study, the fact that molecular receptors capable of interacting with these compounds are common in humans and extending beyond our brain throughout the body makes their potential huge. This also explains that your study is so extensive, covering from neurodegenerative diseases to cancer. Synthesizing compounds. If we want to develop treatments through these compounds, understand how they are naturally synthesized in plants is vital. That is why it is relevant to the fact that the team managed to reveal the biochemical process used by the plant in the production of these compounds. In his study, the team used high -resolution mass spectroscopy, with which he identified the Cannabinoids contained in the plant. He combined with nuclear magnetic resonance with the aim of finding the structure of some of the compounds found. From there, the team could reveal the biochemical “path” followed by the plant when it comes to synthesizing these cannabinoids. The details of the process were published In an article In the magazine Nature Plants. CBG. Of the 40 compounds found in the plant, only half a dozen are present in marijuana. In fact, the team points out, neither the THC nor the CBD are present in the Lanudo umbrella. The compound that is common to both plants is the CBG (cannabigerol). From the ritual to the laboratory. The discovery of cannabinoids in this plant is not entirely new. The clues that pointed to this fact date back decades. As explained by the team responsible for the new study, the Lanudo umbrella used to be used in rituals in which he burned to generate “intoxicating” fumes, which encourages us that the tracks were already there. In Xataka | The marijuana paradox: in full legalizing fever, we are increasingly clear than smoking it is harmful Image | Sagit Meir / United States Fish and Wildlife Service

Six fears have defined their career

Jeff Bezos has founded two of the most successful companies in the last decade: Amazon and Blue Origin. His path to success was not only promoted by his leadership skills and his vision of the future, but also for seven fears that marked each and every one of the decisions he has made in his business career. These fears, far from being a weakness, became a force that motivated him to take risks, innovate and Build an empire which has transformed various industries. Since its inception, Bezos knew how to face their fears and turn them into Growth opportunities. 1. The fear of repentance Just as Jeff Bezos himself told Your graduation speech From Princeton, before founding Amazon, Jeff Bezos was a brilliant Wall Street analyst with a promising career. However, he abandoned the security and stability of a well -paid job to launch books online when no one did. To overcome this fear, Bezos developed what his “Repentance minimization framework“. This approach helps him make decisions based on what would bring him more peace of mind in the future, even if he implies taking risks in the present. As he said in An interview In 2001, one of the main fears that defined Bezos’ life was the fear to reach the end of his life and regret not having tried something important. “I realized that I wouldn’t regret trying something important, even if I failed. I knew that would chase me every day.” 2. The fear of losing competitiveness Bezos has always been very aware that success attracts competition, so it is necessary for companies to always remain at the forefront with a mentality that the millionaire called the mentality of “day 1” in its famous 1997 letter to investors of Amazon. This fear has led him to promote a culture of innovation Constant inside Amazon, always looking for one step forward. His obsession with the client and for continuously improving the services has kept him alert to the movements of his competitors to place one step ahead. “The second day is stagnation, followed by irrelevance, followed by an unbearable and painful decline, followed by death,” he said in his manifesto. A clear example of this was the Amazon Prime developmenta service that revolutionized the expectations of consumers in terms of fast shipments and digital content. This strategy was born from the fear of being overcome by other technological companies that also sought to captivate the public. 3. The fear of garages Directly related to the previous point. His “urgency” philosophy has driven him to act quickly in the design and development of new ambitious projects. For him, every moment counts, and inaction can be a more dangerous enemy than his own error. Jeff Bezos claims not to be afraid of his great competitors who, guiding himself by trends, can more or less predict. His true fear comes from a garage. “I am more afraid of two kids in a garage, than the competitors I already know,” assuredIn an interview. The great ideas and products that have changed the technology of the last 40 years have not come out of huge hierarchical structures in multinational, but have been the ideas of young people who have developed With just resourcesbut with large amounts of commitment and innovation. As he himself did when founding Amazon from the garage. 4. The fear of failure: CEO paranoia Although he is one of the most successful businessmen in the world, Bezos is not immune to fear of failure. It is not the only one. CEOs and managers of successful companies such as Jensen Huang de Nvidia or Peter Beck of Rocket Lab also They have confessed feel what is already known as “CEO paranoia”: a atrocious fear to fail and that their companies are ruined. However, these managers see failure as an essential part of the Innovation and growth process. They are aware that assuming risks means accepting that some ideas will not work, but also that these errors are opportunities to learn and improve. “I asked everyone here to wake up terrified every morning, with the sheets soaked in sweat,” assured The millionaire Fortune. 5. Failure as a lesson for success Despite being a successful millionaire, Jeff Bezos’ career has not been exempt from failures. However, instead of regretting them, he assumes them as part of a growth process. In his Letter to the 2015 shareholdersthe millionaire said: “I think we are the best place in the world to fail (we have a lot of practice!), And the failure and invention are inseparable twins. To invent you have to experiment, and if you know in advance that it will work, it is not an experiment.” An example of that culture of innovation were Alexaand Kindletwo disruptive products, which have finally established themselves in their respective areas. 6. Fear of uncertain future Jeff Bezos has always shown concern about the uncertainty of the future, both personal and global. This fear motivated him to found Blue Origin, his company from Space explorationwith the vision of finding solutions so that humanity can survive beyond the earth. “The land is finite and if the world economy and population will continue to expand, space is the only possible way,” collected Business Insider. Bezos believes that humanity must be able to expand towards other planets to ensure their survival. As he said in the Lex Friedman Podcastthis fear, far from being pessimistic, has become an engine to develop technologies that could change the fate of our species. In Xataka | The next border of the super farms is no longer to be Milmillonarios, is to be Billionaires: Musk, Zuckerberg and Bezos are candidates Image | Wikimedia Commons (Daniel Oberhaus)

The Fyre Festival was the most ruined festival in history. Now his ideologues want to celebrate it in Mexico

There are festivals and then is the Fyre Festival. What happened several years ago on an island in Bahamas will remain for the Annals of History, a non -chaotic festival that ended with its founder in jail and with two documentaries about their won legend as “the worst” of the events of this type in modern history. In fact, there will always be the doubt of whether the productions of Netflix and Hulu always They scam us telling the scam. Be that as it may, for May everything is “almost” ready for the second part. Context: The first failure. The first edition of the festival took place in 2017 and became a epic dye disaster When the attendees, mostly wealthy young people who had paid thousands of dollars for a luxury experience in the Bahamas (with VIP packages that reached 400,000 dollars), they found an event without infrastructure, without musical acts and with deplorable accommodations. The catastrophe (and fraud) was Such proportions which resulted in Millionaire losses For attendees and investors. Its founder, Billy McFarland, was arrested shortly after. In 2018, it was declared guilty of fraud and fraudwith a sentence of six years in prison and A 26 million debt of dollars, although it was released after fulfilling just under four. In spite of everything, McFarland has enthusiast The Today Show program. The second part. This is how we get to these days, although with a certain Leave Vú In the slogan: luxury, exclusivity and exorbitant prices. That is what promises again Fyre Festival 2. Now, with a new scheduled edition from May 30 to June 2, 2025 in Isla Mujeres, Mexico. According to The festival websiteattendees can enjoy avant -garde experiences, musical shows on the beach and world -class hospitality. In fact, tickets They are already on sale From this week, with prices ranging from $ 1,400 to 1.1 million dollars. The latter, The “Prometheus” packageincludes tickets for eight people, flights in “Fyre Air” from Miami to Cancun, helicopter transport and accommodation on a yacht or a four -bedroom villa. Also supposed exclusive experiences such as diving with whale sharks and sessions of Mixology. The first doubts. However, something does not just quad. The details are rather scarce From the official page: Official artists or suppliers have not been announced so far. In fact, if we go to the web we find something very rare: GPS coordinates From the event they point to a point in the sea, west of Isla Mujeres. In Mexico they know nothing. However, what makes all alarm signs jump is that from Isla Mujeres they are not aware of the event. In this regard, Edgar Gasca, from the Island Directorate of Isla Mujeres, was blunt to affirm: “We have no knowledge of this event or contact with any person or company about Him. For us, this is an event that does not exist”. In fact, Gasca He explained to the Guardian that upon learning of the announcement he investigated with the Ministry of Tourism of Quintana Roo and with the hotels that would supposedly offer accommodation for the event. The answer? Everyone denied having been contacted by the organizers. One of these hotels, Isla Mujeres impression, assured the British environment that has not received any request or communication from the festival and that are currently investigating the situation. Even the municipal president of Isla Mujeres, Athena Gómez Ricalde, has expressed his bewildermentaffirming that the only thing he knows about the festival is what he has read in networks: “They are trying to take advantage of the peace and tranquility we have built here for their own benefit.” A doubtful strategy. McFarland has tried justify lack of details ensuring that attendees knew that “they were taking a risk” when buying tickets and that the event is no longer under their direct control, but in the hands of new partners. Local authorities, however, suspect that the organizers’ strategy is Simply announce the eventmeasure interest and then try to obtain permits on the fly. GASCA described this naiveunderlining that to organize a great magnitude event, prior municipal authorization is required. Given the controversy, the Government of Isla Women has issued A public statement denying the existence of permits for the event. The organizers insist. Despite the official refusal, the Lostnight producer company also issued a statement ensuring that the festival will take place from May 30 to June 2, 2025. According to this statement, the event will have “exclusive places, high -end hotels and compliance with local regulations.” For its part, Unik Travel, another company involved, said there ESTABLISHED CONTACT WITH THE AUTHORITIES municipal and state to guarantee the legality and success of the festival. However, again, none of these statements has been accompanied by concrete evidence. Second parts …: With all this panorama it is little less than a recklessness to buy one of the tickets. The Multiple alarm signalsadded to the lack of transparency and the refusal of local authorities, have generated serious doubts about the viability of the Fyre Festival 2. For Gasca, The situation is clear: “This festival will not happen. There are red flags everywhere.” As proof of the lack of planning, Gasca has indicated what we commented before: that the festival coordinates on its website lead to a location In the middle of the oceanbetween Cancun and Isla women, which illustrates, at least, the precariousness of the project itself. Thus, it is reasonable to think that Netflix already It has a bale The second documentary. Image | Fyre Festival In Xataka | Has the documentary that the Timo of the Fyre Festival counted us? This is what we know In Xataka | A luxury festival that charged $ 12,000 per entrance becomes an uncontrolled yerm

Brussels has asked to apply 5% VAT to electricity to protect industries and homes

The year 2025 entered and the fiscal reduction of electricity ended in Spain, the same one that remained for three and a half years. We have gone from 5% to mitigate the effects of the energy crisis, to which return to its general type of 21%. However, Brussels have other plans. Brussels measure. The European Commission has presented An action plan to make energy more affordable in the EU. This includes a series of measures, such as energy reduction, in order to relieve electricity and energy costs for citizens and companies. The most outstanding measure is the proposal to apply a minimum VAT of 5% in electricity. Reduce VAT. The objective is based on reducing short -term costs for consumers and companies. The energy commissioner, Dan Jørgensen, has estimated Energy savings of 45,000 million in 2025, which will increase up to 130,000 million a year by 2030 and up to 260,000 million annually by 2040. In addition, from the EU they seek to “turn the current situation” characterized by dependence on foreign fossil fuels, the existence of a fragmented electrical system and a continuous increase in system costs. Gas dependence. The European Union has accelerated the emptying of its gas reserves in the last three years Due to the energy crisis. Gas is being one of the great War paradoxesbecause while European funds are destined for Ukraine to help it, Gas and oil are still bought from Russia. This dependence increases the cost of electricity production, especially when gas is used as a primary generation source. For its part, the price of gas has returned to high levels similar to those of 2022, especially affecting industries such as chemistry and metallurgical, which depend on both and energy source and raw material. This increase has been driven by cold temperatures and a lower renewable energy generation. The forecasts indicate that, if the demand remains high and the cold climate persists, the prices They could continue to go upwhich would impact the competitiveness and inflation of industrial products in Europe. So renewables? Another point is clean energies, Europe has a great renewable capacity, but as We have mentioned in Xataka, There are two factors that the EU still has to resolve: the famous “Dunkelflaute”, a period without wind or sun, which reduces the generation of renewables, and an aged electricity, which makes it difficult to transmit. These factors have made the dependence on fossil sources increase, raising costs. The consequences are reflected in a more volatile electricity market and the impact on consumers. And what happens in Spain? The year began with a series of fiscal changes in the country, such as VAT increase. This return to previous tax levels (21%) after the fiscal reduction implemented to mitigate the energy crisis has raised short -term costs. Although this has not been the only climb, they have also increased The Electricity Tax (IEE) and The Value Tax of Electric Power Production (IVPEE). However, a system of Progressive reduction in the social bonus For vulnerable homes, which could mitigate the effects on the most affected by the climb. On the other hand, the fees options, such as the PVPC rate and fixed or variable rates in the free market, will allow consumers to adapt their consumption and select a rate that best suits their needs and patterns of use, which can help optimize costs despite fiscal increases. Although Spain has advanced Towards a greater proportion of renewable energy, factors such as tax rise, dependence on fossil fuels and an aging of the energy network still affect the costs of electricity Image | Pxhere Xataka | Thousands of trapped people, chaos in the streets and a country looking for answers: Chile has faced the worst blackout in 14 years

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