We are obsessed with magnesium as a dietary supplement. Your “overdose” has a name: hypermagnesemia

In recent years, magnesium has become the star supplement for many people. Promoted as the definitive remedy to sleep betteravoid muscle cramps, slow aging or reduce stress, has managed to penetrate a society that has seen these benefits as a real lifesaver for their daily lives. However, taking magnesium without a laboratory-documented deficiency is not only useless, As we have commented on several occasionsbut it can trigger a very dangerous clinical condition. There are differences with respect to the vitamin complexes that we also sin of taking in an abusive way without an analysis involved. And in these cases the excess is usually easily eliminated through urine without major impact, but serum magnesium operates in a very narrow physiological range, and this means that when we saturate our body exceeding its safety limits, the adverse effects manifest themselves in a domino effect that compromises everything from the digestive system to the heart rate. And it’s something we fall into thinking that ‘the more the better’. The balance. Our body has all its parameters well regulated within a range of fairly well-defined values ​​so as not to generate pathology due to excess or deficiency. In this case, different references suggest that the normal value of magnesium in blood ranges between 1.7 and 2.2 mg/dL, and can reach 2.4 mg/dL in some laboratories. Hypermagnesemia is formally diagnosed when these levels exceed 2.5 or 2.6 mg/dL, and the truth is that it is easy to reach these extremes in the case of widespread supplementation when there is no clear deficit. Its effects. In the case of overdoing it with magnesium intakethe first warning that we are going to have will be in the digestive system, since the magnesium here will act by attracting water to the intestine, causing diarrhea, nausea, vomiting and abdominal cramps. But when we increase the excess to a moderate range of between 4 and 6 mg/dL, magnesium begins to act as a depressant of the nervous system and a vasodilator, which translates into a drop in blood pressure and muscle weakness. In serious cases. When levels exceed the barrier of 6 mg/dL, the condition becomes critical, and here the guidelines warn of a profound neuromuscular blockade that can lead to muscle paralysis, which can be fatal if it reaches the respiratory muscles. But it does not stop there, since the cardiovascular system also goes into crisis in this situation, and the electrocardiogram of these patients shows severe alterations that cause it to lose its natural rhythm. The role of the kidney. In completely healthy patients, this organ acts as an extremely filter efficient when it comes to excreting all the excess magnesium through urine. However, when we talk about people who have compromised kidney function, the kidney will not be able to work properly removing magnesium from supplements, so it will accumulate quickly, generating all the complications we have seen before. The physiology. For all this, you cannot take magnesium like a candy, trusting that all the benefits they sell us will magically come true. The recommendation is always to consult a doctor to determine this mineral, and supplement (if necessary) with a maximum between 250 and 300 mg of magnesium per day. Exceeding this dose, especially by consuming multiple supplements or abusing magnesium-containing laxatives, is playing Russian roulette with our electrolyte balance. Images | MIND FAVOR In Xataka | Like so many supplements before, we need to be clear about something about magnesium: it’s not going to work miracles.

There is such a fever for melatonin in children that in the US we already have cases of “overdose”

Over the last decade, melatonin has gone from being a specific resource for him jet lag to become a permanent tenant of millions of families and is present in many places to buy it. And it’s cheap, can be bought without a prescription and has an aura of “natural”. However, science is pointing to a problem it is creating: the use of these hormones in children has skyrocketed. Its main use. At a time when stress is accompanying us on a daily basis, insomnia is undoubtedly a serious problem for anyone, and solution that seems easier is melatonin. Under the pretext that it is something natural and without a prescription (in its lowest concentrations), it can be abused indiscriminately. The problem arises when children who cannot sleep well are also given a melatonin gummy so that they can sleep. Something that has already triggered cases of overdose and chronic treatments without medical supervision. The blind experiment. The study, led by the University of Kansas, has put figures to a trend that pediatricians have been observing in consultation for some time. By analyzing 19 studies (which include children up to 6 years old), researchers have drawn a worrying picture: between 2009 and 2021, accidental ingestions and overdoses of melatonin in minors in the US grew by 500%. And it is something that seems quite normal, since at the beginning the use of melatonin is applied to help sleep on a difficult night, but in the end it is becoming chronic by showing that between 40 and 50% of children who start the treatment continue taking it two or three years later. The problem is that today There is no solid data on the long-term safety or effectiveness of melatonin. in typically developing children. The legal vacuum. One of the big problems in Spain and the European Union is the product label. Currently, melatonin can be found as a dietary supplement in supermarkets, health food stores and countless other places. But it is also available as a medicine with pharmaceutical quality controls and intended primarily to treat chronodisruption severe. This is why some experts, such as Carlos Javier Egea Santaolalla, president of the Spanish Federation of Sleep Medicine Societies (FESMES), warn that this is a major public health problem. The proposed solution? That melatonin is always considered as a medication that must be prescribed to guarantee control of the duration and dose administered. Recommendations under supervision. It is the right thing to do when we talk about using melatonin in the little ones in the house, since it has been seen how it can be useful in children with ADHD to advance sleep. But the problem is that there are no studies that tell us about the consequences of using it for more than two years in a row. This is something that is also conveyed by the Spanish Sleep Society (SES), which recognizes that melatonin is a valuable tool in children with Attention Deficit Hyperactivity Disorder (ADHD) or Autism Spectrum Disorder (ASD). A quality problem. When purchasing melatonin as a supplement, the consumer is faced with a “lottery” of formulations. Previous studies have shown that the actual amount of hormone in an over-the-counter gummy or pill can vary drastically from what the label says (sometimes up to 400% more). For Spanish experts, medicalizing its use would not only limit unnecessary consumption, but would guarantee that what the child ingests is exactly what the doctor has prescribed. In this way, the scientific community has pointed out that melatonin is a powerful drug that disrupts the endocrine system, not a magic solution so that parents can rest. Images | Annie Spratt Myriam Zilles In Xataka | I got my hands on some “sleep headphones” in the hopes of finally falling asleep. It came out regular

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