We have a new clue about depression and we have found it in an unsuspected place: body temperature

Depression is something that goes beyond our brains. Like many other diseases, this psychological ailment is manifested in other aspects of our physiognomy. For example, in our body temperature. Temperature and depression. A study has identified A relationship between body temperature and depression. The team responsible for the analysis observed a positive relationship between the variables, that is, that the appearance of depressive symptoms was linked to a higher body temperature among the participants. The relationship was proportional. The severity of the symptoms, the greater the body temperatures were also. They also observed an apparent relationship between the variability of temperatures and depressive symptoms, but this did not show being statistically significant, so conclusions cannot be extracted in that aspect. Beyond the statistical incidence is little What is known of this relationship. For example, the equipment indicated that it is still an enigma if this increase in body temperature could be due to a loss of control capacity, an increase in temperature generation through metabolic processes, or if it was a combination of factors. More than 20,000 participants. To carry out the study, the team compiled information from 20,880 participants from 106 countries. During the study, which lasted for seven months in 2020, the participants carried a thermometer device to measure their body temperature and daily reported temperature and symptoms of depression. “Let us know, this is the biggest study to examine the association between body temperature (measured both self -assess and through portable sensors) and depressive symptoms in a geographically wide sample,” explained in a press release Psychiatrist Ashley Mason, co -author of work. The study It was published in the magazine Scientific Reports. An old suspicion. Although it is probably the most massive, this is not the first analysis that indicates this relationship. A study published in 2003 He pointed to the existence of this relationship and its possible link with the 5-HTT protein, the “serotonin transporter”. Another important indication has to do with the drugs usually used in the treatment of depression, selective serotonin reuptake inhibitors (SSRI) and serotonin and norepinephrine reuptake inhibitors (SNRI). In recent years, various studies have proven that these compounds reduce thermal tolerance of those who consume them. The main studies in this regard were analyzed In a literature review published in 2022. Correlation and cause. The present study finds a link between temperature and depression but does not indicate the possible form of the causal direction, if there were. It is impossible to determine, through known data if depression causes an increase in body temperature or if a high body temperature can increase our risk of appearing depression. Nor is it possible to rule out that there is an underlying cause of both that the analysis does not see: inflammatory stress or processes could independently cause both depressive symptomatology and an increase in body temperature. Cold or heat as therapy? Understanding what is happening can help us better understand depression and, therefore, bring us closer to the tools we are looking for to fight it. Until now the heat had been used to improve the patient status. These types of therapies could make sense through a “rebound effect”, helping the body to recover its capacity for thermal self -regulation, Add the equipment. In Xataka | The great mystery of our body temperature: it does not stop lowering globally and we still do not know why Image | Tankilevitch polyina *An earlier version of this article was published in June 2024

We had been trying to know what neurostrogens served why they served. We have just discovered a clue: they regulate the appetite

In recent years we have seen progress in the study of the hormones responsible for regulating our appetite and the feeling of satiety, hormones such as those that transmit from the stomach to the brain the information that we have already consumed our ration of food and we can stop. However, now we just found one of these hormones in an unexpected place, in hormones that until now we associated mainly with reproduction. From the stomach to the brain. A Japanese researchers team He has found A relationship between neurostrogens and appetite regulation. Neurostrogen. The Estrogens They are hormones that we usually associate mainly with female reproduction. In this context, aspects such as the development and maintenance of female sexual characteristics regulate. But this “family” of hormones has a diversity of members that cover other contexts. For example we can find the phytostrogen produced by plants or neurostrogens. The latter are produced by the brain, as their name suggests and until now they represented a mystery in our biochemistry since we do not know which or what their exact functions are. Looking for an answer. The team I investigated precisely The role of these brain hormones. For this they turned to mice in a laboratory. They compared several groups of mice, including some without the capacity to produce estrogen; and others to whom the production of neurostrogens had been inhibited. The latter was eliminated by aromatase, an enzyme used by the brain to synthesize these hormones. They thus verified that the group of mice that lacked ovaries and those without aromatase showed a greater body mass and greater food consumption compared to the mice of the control group. The team Then he reactivated The gene linked to aromatase, returning the enzyme to its brains. They saw that the mice went on to consume less food. MC4R. The team found that these mice to whom the ability to synthesize aromatase had been returned and with it neurostrogens showed a “marked increase” in the expression of the melanonortine 4 (MC4R) receptor, a receptor known for its role in the regulation of food consumption. This led the team to conclude that the neurostrogens produced through aromatase were involved in the expression of the receiver and that it was through it that were able to “suppress” the feeling of hunger. The role of leptin. The study, explains the responsible team, also indicated that neurostrogens could also increase the ability of the brain to leptin, one of the hormones whose function we already knew related to the regulation of appetite. “We observe that mice with restored neurostrogens responded more effectively to leptin treatment,” explained in a press release Takanori Hayashi, co -author of the study. “This may be due to the fact that neurostrogen increases the natural response of the body to the mechanisms that suppress appetite.” The details of the study were published In an article In the magazine The Febs Journal. The eye put into treatments. The team responsible for the study Mention the possibility that this discovery opens new therapeutic paths focused on development detracts for weight loss. They also point out that understanding the physiological function of neurostrogen could also help us find ways to regulate estrogen more precisely in our bodies, for example in contexts such as menopause or postpartum. In Xataka | We already know where the microplastics get the lettuce that you eat in the salad: from the air Image | Milad Fakurian / Sander Dalhuisen

Genetics offers some clue to answer the eternal question: What the hell goes through my cat’s head?

Who has lived with a cat has probably intrigued more than once by the sometimes incomprehensible Gatuna Psychology. Now, a project seeks to respond to some of the mysteries that surround the behavior of these felines in the hope that their psychology is not, after all, completely impossible to understand. Cats are sought. And the first step to achieve this is in Create a database with information about numerous cats of various races and contexts. It is precisely what the Darwin cat initiative team is doing, or Darwin’s Cats. Plans. He objective of this project It is to collect 100,000 cats enrolled in June 2026, although they have not yet reached the 10,000 mark. The team seeks to gather information on the behavior of felines through a questionnaire and information about the genetics of each individual. For the latter, participants will have to send a hair sample from the animal next to the questionnaire. Combining these data, the team hopes to obtain the highest database of its kind to investigate not only in the behavior of these domesticated animals, but also expand our knowledge about their health. Who wants to register your pet, yes, you must pay a donation of about $ 150, in order to finance the investigation. In Xataka Communicating with our cats has always been a complex task. A study has discovered the key: flashing Darwin’s ark. This project is not the first in its style for the team that undertakes it. The initiative is part of the work of the Darwin Ark Association (Darwin’s Ark), which a few years ago made Similar work With dogs. Behind the project There is a team of researchers linked to the Chan School of Medicine of the University of Massachusetts and Broad Institute. Inquiring in feline psychology. Perhaps because of the contrast between dogs and cats or perhaps because their behavior really is strange to us, the psychology of cats has intrigued many throughout the long history of coexistence between felines and humans. So strange is sometimes the behavior of these animals that we have come to apply evidence aimed at detecting psychopathy trends in these animals. In recent years, this field of study has put some emphasis In the genetics of cats when confirming some ideas about the existence of hereditary features in the personality of these animals. A quite widespread notion but that we are still understanding. {“Videid”: “x95dxwi”, “Autoplay”: fals, “Title”: “The strongest animal measures 1mm so are the most fearsome animals”, “Tag”: “Webedia-prod”, “Duration”: “343”} Health issue Understanding the genetics of these mammals goes beyond finding patterns in their behavior. It can also help us when detecting genetic components of some of the diseases that affect cats and thus be able to find ways to improve veterinary attention to these animals. Perhaps they can even help us prevent or cure some of the diseases and disorders that affect very present animals in our environment. In Xataka | The ‘Maullido Division’, when Russia released 5,000 cats to help in World War II Image | Vitolic Mana (Function () {Window._js_modules = Window._js_modules || {}; var headelement = document.getelegsbytagname (‘head’) (0); if (_js_modules.instagram) {var instagramscript = Document.Createlement (‘script’); }}) (); – The news Genetics offers some clue to answer the eternal question: What the hell goes through my cat’s head? It was originally posted in Xataka by Pablo Martínez-Juarez .

Log In

Forgot password?

Forgot password?

Enter your account data and we will send you a link to reset your password.

Your password reset link appears to be invalid or expired.

Log in

Privacy Policy

Add to Collection

No Collections

Here you'll find all collections you've created before.