Our body is full of almost indestructible “eternal chemicals.” It turns out that we have the solution in the intestine

“Eternal chemicals” is a name with great loudness. They are practically indestructible molecules, and the problem is that they are really harmful for both nature and us. In recent years we are taking it seriously and we have sought Remove them with guns with electron beams. Also through forms of break their molecular bondsand now a bacterium can become an ally to end these eternal chemicals.

And it will be as easy as taking a capsule.

A slow poison. The perfluoroalquiladas and the polyfluoroalquiladas, known as PFASThey are a relative of about 4,700 synthetic molecules that have great resistance due to the unions between fluorine and carbon atoms. They are very useful for that resistance, since the molecular union is very stable and does not react to external agents. The problem is that they are used in many products (hygiene, textiles, pesticides, containers or Even in the wine), they accumulate in nature by not being destroyed and, potentially, also in our body.

PFAS and their derivatives, such as trifluoacetic acid, are related to soil contamination and water sources. And the prolonged exposure to certain PFAS has been related With a higher risk of kidney cancer and testicles, alterations in the immune system, changes in cholesterol, fertility problems and increased blood pressure in pregnancy.

Intestinal bacteria. That is why we commented on some lines: we are looking for how to end them. It is difficult, but researchers from the University of Cambridge have TOP With an unexpected ally: human intestinal bacteria. Specifically, the Faecalibacterium prausnitziian intestinal bacterium that, together with others found in our body, has proven to be very effective absorbing pfas.

In experiments, and as they point out in Natureresearchers have found about 38 bacterial strains that absorb these eternal chemicals. Basically, they quickly accumulate great concentrations of PFAS minutes after exposure to them. How do they do it? Catching toxic compounds within cell groups, protecting both themselves and the host. Come on, putting the pfa in quarantine.

Swallowing more and more. To test it, the toxicology unit of the University of Cambridge experienced with mice that had ingested PFAS. They introduced nine bacterial strains in their organism and observed that these bacteria quickly trapped the PFAS and then were naturally expelled through the feces.

The interesting thing is that bacteria work more intensely at greater concentration, with constant elimination rates of between 25% and 74% of the PFAS present in the body.

Horizon. Studies are constantly published in which they tell us how they have discovered the potential of something to improve our life, but usually, the conclusion is usually a “we need more evidence and we will see.” In the case of bacteria that engulf eternal chemicals, researchers have something clearer what the road map is after those first experiments in mice.

In the next steps, they will explore the development of Probiotics specifically aimed at improving our defenses against PFAS, and they have it so clear that they have founded a startup of biotechnology To develop these products. The objective is that the first is ready by 2026 and what these specialized probiotics will do will be to capture chemicals before they are reabsorbed in the intestine and “encapsulate them” for excretion through the digestive system.

Images | Cambridge University

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