Ozempic He began his career as a drug against diabetes but became one of the most popular medications worldwide when we realized that among its “side effects” was weight loss. Since then we have been detecting other possible effects, positive and negative but surely the most surprising of these is on its effects on fertility.
Set deals with the phenomenon of the “Ozempic Babies”
The United Kingdom warns. The authority responsible for regulating drugs and health products in the United Kingdom, MHRA (Medicines and Healthcare Products Regulatory Agency) warned a few days ago of a “new” side effect associated with the consumption of Ozempic, that of an increase in pregnancy probability. While this is the first time that the organism warns about the effect, the first news about this occurred More than a year ago.
How it works. Ozempic is the brand with which Danish pharmaceuticals Novo Nordisk markets a diabetes treatment based on semaglutida. This compound also serves as a basis for Wegovyname under which the drug oriented to weight loss is marketed.
To understand why the same compound can function as a treatment against diabetes and as a thinning we have to understand how it acts in our body. The semaglutida works as an agonist of the peptide receptors similar to glucagon-1 (LPG-1), that is, it works as an analogue of this key hormone in the digestive process.
When we eat our body naturally secretes the GLP-1 hormone to transmit two messages. The first to the pancreas, so that it begins to segregate insulin with which to metabolize the sugars of the food. The second to the brain, so that this knows that we are satiated. Drugs like Zepbound and Mounjaro They act similarlyalthough the tirzepatida on which they are based works as a double analogue of LPG-1 and GIP hormones (gastric inhibitor polypeptide).
Ozempic Babies. A little over a year ago, dozens of women in treatment with any of these medications They started informing of a strange phenomenon: They were becoming pregnant despite being considered infertile or despite resorting to contraceptives. This phenomenon was soon baptized as the “Ozempic Babies“,” Ozempic babies. “
How do you do it? Since the phenomenon began to document, many wondered how it was possible. There are two mechanisms (alternative or complementary) that can explain this phenomenon. The first has to do with contraceptives, specifically with oral contraceptives.
One of Ozempic’s effects is that of slow down our digestionwhich in turn makes nutrients and other compounds absorb more slowly. In the preparation of an oral treatment, absorption speed is an important variable to take into account. Drugs such as contraceptives are designed for specific speeds, if these change too much, treatment can lose efficacy.
He Another mechanism that could explain this phenomenon has to do with its slimming effect. As experts also highlight, there is an inverse relationship between obesity and overweight and fertility. It is possible, that by facilitating weight loss the drug is also contributing to increasing the probabilities of pregnancy.
A double problem. The problem is double since it not only implies a greater probability of an unwanted pregnancy; also because this type of treatments They are contraindicated Not only for pregnant women, but also in those who seek to be. According to the recommendations, who wants to find a pregnancy should interrupt these treatments At least two months In advance to allow our body to return to normal and avoid unnecessary risks in a process as complex as gestation.
Positive effects and negative effects. The “fever” by Ozempic and the drugs of its class began with a side effect: a medication aimed at treating diabetes made those who consumed it lose weight. The demand for these compounds has allowed us to find other possible Side effectspositive and negative, on which we have a greater or lesser degree of certainty.
Possible adverse effects documented by the manufacturer itself can find problems such as aggravation of diabetic eye disease, potential allergic reactions and a variety of gastrointestinal symptoms, from nausea to constipation.
However, since it also began to be used We have found indications on other possible effects. Some positives such as helping the fight against addictions or possible effects on renal health either cardiovascular. In the negative face we have also found indications of loss of hair and eye problems.
Image | Chemist4u / Camylla Battani
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