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In the fight against cancer there are many ‘weapons’ that we have at our disposalsuch as chemotherapy or radiotherapy. The problem is that these are assimilated like bombing a city to destroy a single house: it is achieved, but with a lot of collateral damage. But this can be solved if We attack only what interests usin this case a tumor cell, and science points to one of the rarest elements on the planet as a candidate to achieve this. Where are we now. The goal of science is to find the most specific therapies possible so that they attack a tumor cell and not a healthy cell with the aim of reducing the adverse effects of the treatment and also being more effective. For this there are different options such as immunotherapy or the use of very specific antibodies, but there is still a long way to go. A particle. He astatinewhose name comes from the Greek astats (“unstable”), lives up to its name. It is the rarest natural element on Earth and disappears almost as soon as it is formed and that is very interesting to us. Especially a ‘version’ of this element which is At-211 which has a half-life of only 7.2 hours. But this instability is part of its magic. At-211 is what Texas A&M scientists call a “Goldilocks” isotope: perfect for the job. Its advantages. Currently, heto traditional radiation used in cancer treatments have a great impact on the body when traveling over long distances. But At-211 emits alpha particles, which is a heavy, slow-moving helium nucleus, which when emitted releases an enormous amount of energy, but can only travel a tiny distance, just the thickness of a few cells. This is crucial. Targeted Alpha Therapy involves “gluing” an atom of At-211 to a molecule (such as an antibody) designed to specifically seek out and bind to cancer cells. At-211 travels through the body, ignoring healthy cells, and when it finds its target, it anchors to the tumor and releases its alpha particle. The result is a localized and devastating explosion of energy, which irreversibly destroys the DNA of the cancer cell. But since the particle cannot travel any further, the healthy cell next to it will not be affected, making this an almost perfect killer. Your problem. At first glance everything seems great, but… Why don’t we use it? The answer lies in its availability, since it is impossible to mine astatine, since with a life of 7.2 hours the clock is running against it. The only way to obtain it is to create it artificially in a cyclotron, a particle accelerator. The process basically involves firing a beam of alpha particles at a Bismuth-209 target. Now the advance that has been achieved is to create a fully automated system to produce and ship the AT-211 as quickly as possible so that it can be used. In Europe. With this advance, which has been made in Texas, processing time is reduced and the safety of technicians who do not have to handle this substance increases. And while Texas A&M resolves supply in the US, Europe is making a move. The project Accelerate.EUfunded by the European Union, was launched at the end of 2024 with a clear objective: to create a robust and sustainable manufacturing and treatment infrastructure for At-211 throughout Europe. The project focuses on especially difficult-to-treat cancers, such as pancreas, breast and brain tumors (glioblastomas), demonstrating that this therapy is a global strategic priority. The future therefore lies in the possibility of using one isotope to illuminate the tumor and then using another to kill it, inaugurating authentic personalized nuclear medicine. Images | freepik In Xataka | The most unexpected treatment against cancer is LED light, and it is giving good results