If the alcohol industry no longer had enough problems, it has now encountered one more: Ozempic

The drugs of the family of the GLP-1 hormone (peptide similar to type 1 glucagon) as Ozempic or Zepbound have meant a revolution in the world pharmaceutical market. The success of these medications aimed at the treatment of diabetes has to do with its slimming effect but the ramifications of this phenomenon go further. New tests. One of these ramifications has to do with alcohol consumption: a new study He has found evidence That the semaglutida, the active compound used by drugs such as Ozempic or Wegovy, can also help in the treatment of alcohol addiction. Chronicle of a social phenomenon. Ozempic began to gain popularity about two years ago when it began to be used not to keep glycemic levels under control in people with type II diabetes, but as a treatment to lose weight both in people with diabetes and in those who only wanted to lose weight. In parallel, several clinical trials endorsed this effect and the regulatory organisms approved the use of the drug for this second use. This success led to the appearance of other side effects associated with this compound, some of them positive. It was then that some laboratories got to work to test these effects. Among them An apparent reduction in alcohol consumption among those who were under this treatment. How does it work? The GLP-1 hormone performs several functions in our body, one of them being indicating that we have satiated our appetite. That is why the drugs that function as their analogues in our body generate the same feeling of satiety, which in turn implies that we will eat less and therefore lose weight. But soon some users began to realize that this not only affected food, but also the alcohol they consumed. Although the mechanism is not entirely clear, it is possible to intuit that it is the same mechanisms that enter into operation. There is another factor to take into account, and among the Side effects From ozempic drugs we can find stomach symptoms such as nausea and vomiting. This can also lead to alcoholic beverages less appealing, as well as other foods. 48 participants. The study was conducted through a randomized rehearsal with placebo. That is to say, It was distributed randomly to the 48 participants in two groups: one was treated with semaglutida and another with a placebo. They contrasted that the effects of treatment were greater than those of a simple placebo, that is, the participants drank less alcohol. While the number of days in which the participants drank these were not reduced in less volume. “These data suggest the potential of the semaglutida and drugs similar to covering an existing need for treatment for alcohol use disorder,” explained in a press release Klara Klein, member of the study responsible for the study. “Broader studies (…) are necessary to fully understand security and efficacy in people with (this) disorder, but these initial results are promising.” The team presented the details of the essay In an article In the magazine Jama Psychiatry. The analyzes continue. The reduced sample size in this study suggests that there is still a lot of work to be done. If we want to better understand Ozempic’s potential to fight addictions and similar disorders will need experiments with greater samples and studies that allow us to better understand the underlying biological mechanisms, as well as the potential risks of this use. All this while other teams investigate other potential risks and benefits of this drug family. An example of the potential benefits still to explore is In cardiac healthcontext in which we have begun to see some potential benefits but that, as in the case of excessive alcohol consumption, we must still explore more thoroughly. In Xataka | In Tinder there is a trend that is gaining weight between generation Z: quotes without a single drop of alcohol Image | Andreas m / Chemist4u

In a town in Badajoz they have encountered a strength of 5,000 years ago. And a Roman with a suspicious burial

The Spanish territory is is filling with solar panels. Whether it’s Taking advantage of the roofs of industrial estates or in huge Photovoltaic plants in the middle of the fieldenergy are clear that we must take advantage of the country’s solar potential. What happens is that, from time to time, they run into unforeseen events. Such as, with a huge strength of copper age. Photovoltaic archaeologists. This was precisely what happened in 2021, when Action was inspecting an olive grove to lift the Extremadura I-II-III photovoltaic complex. The plan was to have an installation that, together, provided 125 MW of renewable energy, enough to satisfy the annual consumption of more than 65,000 families. Then, I know They encountered With a wall. Or what should have been a wall 5,000 years ago. Cortijo Lobato. Near the municipality of Almendralejo in which Actiona was carrying out the works, the plant appeared of what, at some point, must have been an imposing fortification. As they tell The countryin the baptized as a Cortijo Lobato site, a fortress composed of three concentric walls, 25 semicircular towers and three grave with four meters wide and two depth was erected. The total area was about 13,000 square meters with a single entrance of less than a meter wide. The most important tower rose on a hill of more than 300 meters above sea level, a strategic point from which to control the surroundings. Around it, adobe walls between 1.3 and 1.5 meters wide that were reinforced with the aforementioned concentric exterior pits and walls. You can see the silhouette of the towers and the walls Undermining morality. César Pérez is the director of the excavations, belonging to the Archaeological Research Team of Tera, and argues that this intricate defensive complex not only had as its objective to be a physical barrier, but to discourage whoever wanted to cross it. The problem is that, although it was raised at some point 5,000 or 4,800 years ago, it seems that, 400 years, then it was destroyed. The culprit: a fire. And it is estimated that it was caused, because the wooden doors would be strategically placed outside any flammable material. In addition, numerous arrow points have been found, suggesting that, either it was an enemy attack, or an act of internal rebellion. The result was the same: the destruction of the complex. Three years of work. At the time of discovery, the archeology team focused on protecting the surroundings of Cortijo Lobato. Cease commented A few months ago, during the first three years, “it has been possible to delimit, conserve and it is now when it is being known in depth. We have the possibility to document it to make it known to society, which is to whom the site belongs. ” At the same time, energy continued with its plans to lift the complex, but adapting to the situation. “We had to modify the project as a kind of ‘tetris’ to adapt the configuration of the panels to the different areas of the deposit. In the end, we have managed to preserve the generation capacity at the same time that it was possible to protect all the areas of archaeological interest that have been discovered, ”said Jenifer Andreu, from Actiona. Roman mystery. However, the story had a little girl, which gave the discovery of a mysterious grave. Montserrat Girón is the Coordinator of Archaeological Teams of Tera and comments that they have focused on giving a first sweep to pave the way to following investigations. And it turns out that they have not only found the remains of the inhabitants of the 2800 BC, but also of the 5th century DC Specifically, an almost superficial tomb that had the remains of a male between 25 and 35 years old who lived in the time of the low Roman Empire. He was face down and with a military dagger on his back. You cannot know if nailed or not, but Montserrat jokes saying that, although it is a mystery, it does not look good. Face down and with a dagger on the back. It may be that of that person and be buried with him as a tribute … or who was killed The reason is that, beyond the dagger, the body was whole, except the feet, which seem to have been cut, and the grave had much smaller dimensions than necessary for a body of that size, indicating that it was a Hurd burial. As much as it may be, the efforts at this time is to continue investigating the area of ​​this huge bastion in which they have appeared multitude of vestiges such as loom plates, plates, flint arrow tips, chisels and even ornamental and religious elements. Images | Tera Act In Xataka | We have found new vestiges of the Roman era. We are not very sure what they did in a cave of the Pyrenees

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