In those wheat macaroni that are in your shopping basket, in the jar of lentils or even in the beer there may be traces of glyphosatewhich is probably the most used herbicide on the planet. Weeds are common in agriculture and this chemical is highly effective. However, you can minimize its presence by avoiding ultra-processed cereals, opting for local products from the EU or better yet, buying organic.
We were looking wrong. We know that glyphosate is present in the environment and the European Union regulates the limits maximum residues, but the reality is that there has always been difficulty in accurately measuring how much reaches our body. Because until now, we almost always looked in urine. This international study published in Science Direct The focus has changed to feces and here things change.
Feces are the black box. Because this research has revealed that feces are a much more precise black box for the analysis of glyphosate in humans than urine and reveal an alarming reality: exposure to glyphosate is much higher than official statistics say. Urine testing was just the tip of the iceberg.
The reason for this is how our body absorbs and rejects it: glyphosate is expelled through the feces due to its low intestinal absorption rate. Since it cannot pass through the wall of the intestine to reach the blood (from there it would go to the kidneys), it remains trapped there and ends up expelled in the feces. In a 24-hour period, 90% leaves in the feces and only a small amount reaches the urine (between 0.5% and 6% in humans).
Why is it important. Because the international standard for monitoring glyphosate it’s urinewhich implies an underestimation and therefore an underestimation of the risk. Furthermore, this finding affects not only people directly related to agriculture; it is enough to consume common products present in the diet.
And it doesn’t just affect humans: the study also shows its presence in farm animals, domestic cats and even bats, which means that the herbicide is moving throughout the food chain. In short: the study forces us to rethink how we monitor the presence of chemicals when safeguarding public health and the ecosystem.
Modus operandi. This study proposes the use of feces as an alternative and potentially better matrix than urine for glyphosate and its metabolite AMPA (until now, the usual). To do this, they analyzed 716 human fecal samples and 249 animals from 11 countries (10 European and Argentina) taken in 2021. The research team used an advanced analytical chemistry technique called hydrophilic interaction chromatography coupled to tandem mass spectrometry (HILIC-MS/MS).
Thus, glyphosate was detected in 71% of the European samples and in 100% of the Argentinian samples and are much higher than those present in the urine samples for the same individuals, 35% and 86% respectively. They saw glyphosate in conventional and eco farmers, residents of agricultural areas and general consumers.
An alarming biological conclusion. If there is one thing that is clear from the study, it is that if 90% of glyphosate is in the feces and not in the urine, it means that this chemical spends much more time in direct contact with the digestive system than we thought. And therefore, the current safety limits are probably based on incomplete and undersized data, which underestimates the real health risk.
It is not only the toxicity itself (which is low), but also the cumulative effect on the microbiota and long-term cellular damage. And glyphosate can act as a selective antibiotic that alters the intestinal microbiota, killing beneficial bacteria and allowing the proliferation of pathogenic ones, is cataloged As it is probably carcinogenic to humans, it can act as an endocrine disruptor to our hormonal system or induce oxidative stress.
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Cover | Giorgio Trovato and Ibadah Mimpi

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